A new antibiotic kills pathogens without detectable resistance

Lassomycin, a Ribosomally Synthesized Cyclic Peptide, Kills Mycobacterium tuberculosis by Targeting the ATP-Dependent Protease ClpC1P1P2

(2014) Ekaterina Gavrish et al.   CHEMISTRY & BIOLOGY

Prioritized Current Unmet Needs for Antibacterial Therapies

(2014) B Spellberg et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Bacterial phylogeny structures soil resistomes across habitats

(2014) Kevin J. Forsberg et al.   NATURE

An environmental bacterial taxon with a large and distinct metabolic repertoire

(2014) Micheal C. Wilson et al.   NATURE

A roadmap for natural product discovery based on large-scale genomics and metabolomics

(2014) James R Doroghazi et al.   Nature Chemical Biology

MurJ is the flippase of lipid-linked precursors for peptidoglycan biogenesis

(2014) L.-T. Sham et al.   SCIENCE

Transcription inhibition by the depsipeptide antibiotic salinamide A

(2014) David Degen et al.   eLife

Genome sequence-based species delimitation with confidence intervals and improved distance functions

(2013) Jan P Meier-Kolthoff et al.   BMC BIOINFORMATICS

Activated ClpP kills persisters and eradicates a chronic biofilm infection

(2013) B. P. Conlon et al.   NATURE

Platforms for antibiotic discovery

(2013) Kim Lewis   NATURE REVIEWS DRUG DISCOVERY

Minimal inhibitory and mutant prevention concentrations of azithromycin, clarithromycin and erythromycin for clinical isolates of Streptococcus pneumoniae

(2012) K. Metzler et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Interaction of Type A Lantibiotics with Undecaprenol-Bound Cell Envelope Precursors

(2012) Anna Müller et al.   Microbial Drug Resistance

Recover the lost art of drug discovery

(2012) Kim Lewis   NATURE

Penicillin: the medicine with the greatest impact on therapeutic outcomes

(2011) Nelson Kardos et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Identification of FtsW as a transporter of lipid-linked cell wall precursors across the membrane

(2011) Tamimount Mohammadi et al.   EMBO JOURNAL

Tackling antibiotic resistance

(2011) Karen Bush et al.   NATURE REVIEWS MICROBIOLOGY

NRPSpredictor2—a web server for predicting NRPS adenylation domain specificity

(2011) Marc Röttig et al.   NUCLEIC ACIDS RESEARCH

Use of Ichip for High-Throughput In Situ Cultivation of "Uncultivable" Microbial Species

(2010) D. Nichols et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Siderophores from Neighboring Organisms Promote the Growth of Uncultured Bacteria

(2010) Anthony D'Onofrio et al.   CHEMISTRY & BIOLOGY

Plectasin, a Fungal Defensin, Targets the Bacterial Cell Wall Precursor Lipid II

(2010) T. Schneider et al.   SCIENCE

Standard operating procedure for calculating genome-to-genome distances based on high-scoring segment pairs

(2010) Alexander F. Auch et al.   Standards in Genomic Sciences

Digital DNA-DNA hybridization for microbial species delineation by means of genome-to-genome sequence comparison

(2010) Alexander F. Auch et al.   Standards in Genomic Sciences

The Lipopeptide Antibiotic Friulimicin B Inhibits Cell Wall Biosynthesis through Complex Formation with Bactoprenol Phosphate

(2009) T. Schneider et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

An oldie but a goodie – cell wall biosynthesis as antibiotic target pathway

(2009) Tanja Schneider et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Effect of Polysorbate 80 on Oritavancin Binding to Plastic Surfaces: Implications for Susceptibility Testing

(2008) F. F. Arhin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Short Peptide Induces an "Uncultivable" Microorganism To Grow In Vitro

(2008) D. Nichols et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The RAST Server: Rapid Annotations using Subsystems Technology

(2008) Ramy K Aziz et al.   BMC GENOMICS