Nrf2-mediated anti-inflammatory polarization of macrophages as therapeutic targets for osteoarthritis
出版年份 2022 全文链接
标题
Nrf2-mediated anti-inflammatory polarization of macrophages as therapeutic targets for osteoarthritis
作者
关键词
-
出版物
Frontiers in Immunology
Volume 13, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2022-08-12
DOI
10.3389/fimmu.2022.967193
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Itaconate and fumarate derivatives inhibit priming and activation of the canonical NLRP3 inflammasome in macrophages
- (2022) Christopher Hoyle et al. IMMUNOLOGY
- 4‐octyl Itaconate inhibits lipopolysaccharide (LPS)‐induced osteoarthritis via activating Nrf2 signalling pathway
- (2022) Qingchen Zhang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Four-Octyl Itaconate Protects Chondrocytes against H2O2-Induced Oxidative Injury and Attenuates Osteoarthritis Progression by Activating Nrf2 Signaling
- (2022) Peng Zhang et al. Oxidative Medicine and Cellular Longevity
- Melatonin: A novel candidate for the treatment of osteoarthritis
- (2022) Yijian Zhang et al. AGEING RESEARCH REVIEWS
- Itaconate attenuates osteoarthritis by inhibiting STING/NF-κB axis in chondrocytes and promoting M2 polarization in macrophages
- (2022) Libin Ni et al. BIOCHEMICAL PHARMACOLOGY
- Recent Advances in Understanding Nrf2 Agonism and Its Potential Clinical Application to Metabolic and Inflammatory Diseases
- (2022) Min-Ji Kim et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Epigallocatechin Gallate Protects against Hypoxia-Induced Inflammation in Microglia via NF-κB Suppression and Nrf-2/HO-1 Activation
- (2022) So-Ra Kim et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Inhalation of MSC-EVs is a noninvasive strategy for ameliorating acute lung injury
- (2022) Ruijing Zhao et al. JOURNAL OF CONTROLLED RELEASE
- Melatonin abolished proinflammatory factor expression and antagonized osteoarthritis progression in vivo
- (2022) Shan-Chi Liu et al. Cell Death & Disease
- Cell-free fat extract attenuates osteoarthritis via chondrocytes regeneration and macrophages immunomodulation
- (2022) Zhuoxuan Jia et al. Stem Cell Research & Therapy
- The Role of M1/M2 Macrophage Polarization in Rheumatoid Arthritis Synovitis
- (2022) Maurizio Cutolo et al. Frontiers in Immunology
- Heme Oxygenase-1: An Anti-Inflammatory Effector in Cardiovascular, Lung, and Related Metabolic Disorders
- (2022) Stefan W. Ryter Antioxidants
- Effect of Pulsed Low-Intensity Ultrasonography on Symptom Relief and Tibiofemoral Articular Cartilage Thickness Among Veterans Affairs Enrollees With Knee Osteoarthritis
- (2022) Allen D. Sawitzke et al. JAMA Network Open
- Pulsed-Ultrasound Irradiation Induces the Production of Itaconate and Attenuates Inflammatory Responses in Macrophages
- (2022) Atomu Yamaguchi et al. Journal of Inflammation Research
- Effect of Dietary Polyphenols on Osteoarthritis—Molecular Mechanisms
- (2022) Mateja Sirše Life-Basel
- Opsonized nanoparticles target and regulate macrophage polarization for osteoarthritis therapy: A trapping strategy
- (2022) Longfa Kou et al. JOURNAL OF CONTROLLED RELEASE
- Pentraxin 3 regulated by miR-224-5p modulates macrophage reprogramming and exacerbates osteoarthritis associated synovitis by targeting CD32
- (2022) Jianbin Yin et al. Cell Death & Disease
- Granulocyte macrophage colony-stimulating factor has come of age: from a vaccine adjuvant to antiviral immunotherapy
- (2021) Maria Petrina et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Quercetin suppresses apoptosis of chondrocytes induced by IL‑1β via inactivation of p38 MAPK signaling pathway
- (2021) Xiang-Peng Wang et al. Experimental and Therapeutic Medicine
- Pharmacological Targeting of Heme Oxygenase-1 in Osteoarthritis
- (2021) Yohei Sanada et al. Antioxidants
- A Comparative Review of Autologous Conditioned Serum and Autologous Protein Solution for Treatment of Osteoarthritis in Horses
- (2021) Livia Camargo Garbin et al. Frontiers in Veterinary Science
- The immunosuppressive and pro-tumor functions of CCL18 at the tumor microenvironment
- (2021) Ana Patrícia Cardoso et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Maresin 1 alleviates the inflammatory response, reduces oxidative stress and protects against cardiac injury in LPS-induced mice
- (2021) Dan Li et al. LIFE SCIENCES
- Polarized cytokine release from airway epithelium differentially influences macrophage phenotype
- (2021) W. Skronska-Wasek et al. MOLECULAR IMMUNOLOGY
- TRPV1 alleviates osteoarthritis by inhibiting M1 macrophage polarization via Ca2+/CaMKII/Nrf2 signaling pathway
- (2021) Zhongyang Lv et al. Cell Death & Disease
- Auranofin-Mediated NRF2 Induction Attenuates Interleukin 1 Beta Expression in Alveolar Macrophages
- (2021) Stephanie B. Wall et al. Antioxidants
- Myeloid Nrf2 deficiency aggravates non-alcoholic steatohepatitis progression by regulating YAP-mediated NLRP3 inflammasome signaling
- (2021) Peng Wang et al. iScience
- Anti-inflammatory and M2 macrophage polarization-promoting effect of mesenchymal stem cell-derived exosomes
- (2021) Maedeh Arabpour et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- A Targeted Nanosystem for Detection of Inflammatory Diseases via Fluorescent/Optoacoustic Imaging and Therapy via Modulating Nrf2/NF‐κB Pathways
- (2021) Juan Ouyang et al. Small
- Quercetin‐Loaded Ceria Nanocomposite Potentiate Dual‐Directional Immunoregulation via Macrophage Polarization against Periodontal Inflammation
- (2021) Yu Wang et al. Small
- The Macrophage Response Is Driven by Mesenchymal Stem Cell-Mediated Metabolic Reprogramming
- (2021) Noymar Luque-Campos et al. Frontiers in Immunology
- 5-Hydroxymaltol Derived from Beetroot Juice through Lactobacillus Fermentation Suppresses Inflammatory Effect and Oxidant Stress via Regulating NF-kB, MAPKs Pathway and NRF2/HO-1 Expression
- (2021) Su-Lim Kim et al. Antioxidants
- Quercetin Alleviates Osteoarthritis Progression in Rats by Suppressing Inflammation and Apoptosis via Inhibition of IRAK1/NLRP3 Signaling
- (2021) Wenjun Li et al. Journal of Inflammation Research
- The role of the electron transport chain in immunity
- (2021) Maureen Yin et al. FASEB JOURNAL
- The protective effect of quercetin on macrophage pyroptosis via TLR2/Myd88/NF-κB and ROS/AMPK pathway
- (2021) Xing Luo et al. LIFE SCIENCES
- NRF2 Exerts Anti-Inflammatory Effects in LPS-Induced gEECs by Inhibiting the Activation of the NF-κB
- (2021) Hongchu Bao et al. MEDIATORS OF INFLAMMATION
- Nrf2 Regulation by Curcumin: Molecular Aspects for Therapeutic Prospects
- (2021) Seyed Hossein Shahcheraghi et al. MOLECULES
- Rosiglitazone Suppresses Renal Crystal Deposition by Ameliorating Tubular Injury Resulted from Oxidative Stress and Inflammatory Response via Promoting the Nrf2/HO-1 Pathway and Shifting Macrophage Polarization
- (2021) Hongyan Lu et al. Oxidative Medicine and Cellular Longevity
- Fumarate is a terminal electron acceptor in the mammalian electron transport chain
- (2021) Jessica B. Spinelli et al. SCIENCE
- Regulatory Effects of Quercetin on M1/M2 Macrophage Polarization and Oxidative/Antioxidative Balance
- (2021) Cheng-Fang Tsai et al. Nutrients
- Exosomes secreted by FNDC5-BMMSCs protect myocardial infarction by anti-inflammation and macrophage polarization via NF-κB signaling pathway and Nrf2/HO-1 axis
- (2021) Hongjuan Ning et al. Stem Cell Research & Therapy
- Macrophage Polarization and Its Role in Liver Disease
- (2021) Cheng Wang et al. Frontiers in Immunology
- Reactive Oxygen Species in Macrophages: Sources and Targets
- (2021) Marcella Canton et al. Frontiers in Immunology
- Monocytes, Macrophages, and Their Potential Niches in Synovial Joints – Therapeutic Targets in Post-Traumatic Osteoarthritis?
- (2021) Patrick Haubruck et al. Frontiers in Immunology
- NOTCH4 Exhibits Anti-Inflammatory Activity in Activated Macrophages by Interfering With Interferon-γ and TLR4 Signaling
- (2021) Susana López-López et al. Frontiers in Immunology
- Resolvin D1 ‐loaded nanoliposomes promote M2 macrophage polarization and are effective in the treatment of Osteoarthritis
- (2021) Ameya A. Dravid et al. Bioengineering & Translational Medicine
- Joint synovial macrophages as a potential target for intra-articular treatment of osteoarthritis-related pain
- (2021) D. Wang et al. OSTEOARTHRITIS AND CARTILAGE
- Krebs Cycle Reborn in Macrophage Immunometabolism
- (2020) Dylan G. Ryan et al. Annual Review of Immunology
- The acetyltransferase p300 regulates NRF2 stability and localization
- (2020) Athina Ganner et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Nrf2/ARE is a key pathway for curcumin-mediated protection of TMJ chondrocytes from oxidative stress and inflammation
- (2020) Chao Jiang et al. CELL STRESS & CHAPERONES
- The role of JAK/STAT signaling pathway and its inhibitors in diseases
- (2020) Ping Xin et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Regulation of Adipocyte and Macrophage Functions by mTORC1 and 2 in Metabolic Diseases
- (2020) William T. Festuccia MOLECULAR NUTRITION & FOOD RESEARCH
- Macrophages regulate the progression of osteoarthritis
- (2020) H. Zhang et al. OSTEOARTHRITIS AND CARTILAGE
- Preconditioning of mesenchymal stromal cells with low-intensity ultrasound: influence on chondrogenesis and directed SOX9 signaling pathways
- (2020) Neety Sahu et al. Stem Cell Research & Therapy
- Cerevisterol Alleviates Inflammation via Suppression of MAPK/NF-κB/AP-1 and Activation of the Nrf2/HO-1 Signaling Cascade
- (2020) Md Badrul Alam et al. Biomolecules
- Steady Augmentation of Anti-Osteoarthritic Actions of Rapamycin by Liposome-Encapsulation in Collaboration with Low-Intensity Pulsed Ultrasound
- (2020) Chung-Hwan Chen et al. International Journal of Nanomedicine
- The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation
- (2020) Alexander Hooftman et al. Cell Metabolism
- Dual delivery of stem cells and insulin-like growth Factor-1 in coacervate-embedded composite hydrogels for enhanced cartilage regeneration in osteochondral defects
- (2020) Hyeran Cho et al. JOURNAL OF CONTROLLED RELEASE
- Redox Regulation of STAT1 and STAT3 Signaling
- (2020) Elena Butturini et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- NOTCH3 signaling is essential for NF-κB activation in TLR-activated macrophages
- (2020) Susana López-López et al. Scientific Reports
- Prevention of acute kidney injury by low intensity pulsed ultrasound via anti-inflammation and anti-apoptosis
- (2020) Chih-Kang Chiang et al. Scientific Reports
- Mesenchymal stem cell-derived extracellular vesicles alter disease outcomes via endorsement of macrophage polarization
- (2020) Jiangmei Wang et al. Stem Cell Research & Therapy
- Electrophilic Nrf2 activators and itaconate inhibit inflammation at low dose and promote IL-1β production and inflammatory apoptosis at high dose
- (2020) Jonathan Muri et al. Redox Biology
- SOD1 suppresses pro-inflammatory immune responses by protecting against oxidative stress in colitis
- (2020) Jiyoung Hwang et al. Redox Biology
- An Overview of Nrf2 Signaling Pathway and Its Role in Inflammation
- (2020) Sarmistha Saha et al. MOLECULES
- Adipose mesenchymal stem cell-derived antioxidative extracellular vesicles exhibit anti-oxidative stress and immunomodulatory effects under PM2.5 exposure
- (2020) Yongheng Gao et al. TOXICOLOGY
- Melatonin in macrophage biology: Current understanding and future perspectives
- (2019) Yaoyao Xia et al. JOURNAL OF PINEAL RESEARCH
- Specificity, versatility, and control of TGF-β family signaling
- (2019) Rik Derynck et al. Science Signaling
- Clinical implications of macrophage dysfunction in the development of osteoarthritis of the knee
- (2019) Jinwei Xie et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Hippo signaling controls NLRP 3 Activation and governs immunoregulation of mesenchymal stem cells in mouse liver injury
- (2019) Changyong Li et al. HEPATOLOGY
- Metabolic immunomodulation of macrophage functional plasticity in nonhealing wounds
- (2019) Catherine B. Anders et al. CURRENT OPINION IN INFECTIOUS DISEASES
- TLR4 activation alters labile heme levels to regulate BACH1 and heme oxygenase-1 expression in macrophages
- (2019) Kritika Sudan et al. FREE RADICAL BIOLOGY AND MEDICINE
- Curcumin attenuates collagen-induced rat arthritis via anti-inflammatory and apoptotic effects
- (2019) Qirui Wang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Curcumin attenuates oxidative stress in RAW264.7 cells by increasing the activity of antioxidant enzymes and activating the Nrf2-Keap1 pathway
- (2019) Xinyu Lin et al. PLoS One
- Locally renewing resident synovial macrophages provide a protective barrier for the joint
- (2019) Stephan Culemann et al. NATURE
- Inhibitory effects of berberine on proinflammatory M1 macrophage polarization through interfering with the interaction between TLR4 and MyD88
- (2019) Jing Gong et al. BMC Complementary and Alternative Medicine
- Berberine Attenuates Cholesterol Accumulation in Macrophage Foam Cells via Suppressing AP-1 Activity and Activation of Nrf2/ HO-1 Pathway
- (2019) Xue-Juan Yang et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Modulation of M2 macrophage polarization by the crosstalk between Stat6 and Trim24
- (2019) Tao Yu et al. Nature Communications
- Glutathione Induced Immune-Stimulatory Activity by Promoting M1-Like Macrophages Polarization via Potential ROS Scavenging Capacity
- (2019) Da Hye Kwon et al. Antioxidants
- Nuclear Factor Kappa B Signaling Complexes in Acute Inflammation
- (2019) Sergio Rius-Pérez et al. ANTIOXIDANTS & REDOX SIGNALING
- Quercetin alleviates rat osteoarthritis by inhibiting inflammation and apoptosis of chondrocytes, modulating synovial macrophages polarization to M2 macrophages
- (2019) Yue Hu et al. FREE RADICAL BIOLOGY AND MEDICINE
- Quercetin Promotes Diabetic Wound Healing via Switching Macrophages From M1 to M2 Polarization
- (2019) Jia Fu et al. JOURNAL OF SURGICAL RESEARCH
- Acid-activatable polymeric curcumin nanoparticles as therapeutic agents for osteoarthritis
- (2019) Changsun Kang et al. Nanomedicine-Nanotechnology Biology and Medicine
- Lumican is upregulated in osteoarthritis and contributes to TLR4-induced pro-inflammatory activation of cartilage degradation and macrophage polarization
- (2019) G. Barreto et al. OSTEOARTHRITIS AND CARTILAGE
- Iron nanoparticle-labeled murine mesenchymal stromal cells in an osteoarthritic model persists and suggests anti-inflammatory mechanism of action
- (2019) Amanda M. Hamilton et al. PLoS One
- Intrarenal Transplantation of Hypoxic Preconditioned Mesenchymal Stem Cells Improves Glomerulonephritis through Anti-Oxidation, Anti-ER Stress, Anti-Inflammation, Anti-Apoptosis, and Anti-Autophagy
- (2019) Hao-Hsiang Chang et al. Antioxidants
- Ulinastatin attenuates LPS-induced inflammation in mouse macrophage RAW264.7 cells by inhibiting the JNK/NF-κB signaling pathway and activating the PI3K/Akt/Nrf2 pathway
- (2018) Si-tong Li et al. ACTA PHARMACOLOGICA SINICA
- Synovial macrophage M1 polarisation exacerbates experimental osteoarthritis partially through R-spondin-2
- (2018) Haiyan Zhang et al. ANNALS OF THE RHEUMATIC DISEASES
- Cartilage repair in degenerative osteoarthritis mediated by squid type II collagen via immunomodulating activation of M2 macrophages, inhibiting apoptosis and hypertrophy of chondrocytes
- (2018) Meilu Dai et al. BIOMATERIALS
- Quercetin attenuates mitochondrial dysfunction and biogenesis via upregulated AMPK/SIRT1 signaling pathway in OA rats
- (2018) Linan Qiu et al. BIOMEDICINE & PHARMACOTHERAPY
- Neochlorogenic acid inhibits against LPS-activated inflammatory responses through up-regulation of Nrf2/HO-1 and involving AMPK pathway
- (2018) Sun Young Park et al. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
- Macrophage plasticity, polarization, and function in health and disease
- (2018) Abbas Shapouri-Moghaddam et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach
- (2018) Antonio Cuadrado et al. PHARMACOLOGICAL REVIEWS
- The Pharmacokinetics of Fumaric Acid Esters Reveal Their In Vivo Effects
- (2018) Ulrich Mrowietz et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Peripheral Mechanisms Contributing to Osteoarthritis Pain
- (2018) Delfien Syx et al. Current Rheumatology Reports
- NF-kappaB: Two Sides of the Same Coin
- (2018) Bruno Pires et al. Genes
- Interferon Gamma Induces Reversible Metabolic Reprogramming of M1 Macrophages to Sustain Cell Viability and Pro-Inflammatory Activity
- (2018) Feilong Wang et al. EBioMedicine
- Therapeutic potential of hyaluronic acid/chitosan nanoparticles for the delivery of curcuminoid in knee osteoarthritis and an in�vitro evaluation in chondrocytes
- (2018) Jian Wang et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
- (2018) Evanna L. Mills et al. NATURE
- Intra-Articular Delivery of Quercetin Using Thermosensitive Hydrogel Attenuate Cartilage Degradation in an Osteoarthritis Rat Model
- (2018) Sze-Wing Mok et al. Cartilage
- Chemokine-Induced Macrophage Polarization in Inflammatory Conditions
- (2018) Pieter Ruytinx et al. Frontiers in Immunology
- Pro-inflammatory cytokines: The link between obesity and osteoarthritis
- (2018) Tiantian Wang et al. CYTOKINE & GROWTH FACTOR REVIEWS
- M2b macrophage polarization and its roles in diseases
- (2018) Le-xun Wang et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Redox regulation of cardiovascular inflammation – Immunomodulatory function of mitochondrial and Nox-derived reactive oxygen and nitrogen species
- (2017) Philip Wenzel et al. FREE RADICAL BIOLOGY AND MEDICINE
- Melatonin protects mice against stress-induced inflammation through enhancement of M2 macrophage polarization
- (2017) Woo-Jin Yi et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Peanut arachidin-1 enhances Nrf2-mediated protective mechanisms against TNF-α-induced ICAM-1 expression and NF-κB activation in endothelial cells
- (2017) Lih-Geeng Chen et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Paralemmin-3 contributes to lipopolysaccharide-induced inflammatory response and is involved in lipopolysaccharide-Toll-like receptor-4 signaling in alveolar macrophages
- (2017) Xu-Xin Chen et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Targeting and modulating infarct macrophages with hemin formulated in designed lipid-based particles improves cardiac remodeling and function
- (2017) Tamar Ben-Mordechai et al. JOURNAL OF CONTROLLED RELEASE
- Chondroitin sulphate inhibits NF-κB activity induced by interaction of pathogenic and damage associated molecules
- (2017) T.V. Stabler et al. OSTEOARTHRITIS AND CARTILAGE
- The Nrf2-ARE signaling pathway: An update on its regulation and possible role in cancer prevention and treatment
- (2017) Violetta Krajka-Kuźniak et al. Pharmacological Reports
- Future therapeutic targets in rheumatoid arthritis?
- (2017) Tommy Tsang Cheung et al. Seminars in Immunopathology
- The Roles of Insulin-Like Growth Factors in Mesenchymal Stem Cell Niche
- (2017) Amer Youssef et al. Stem Cells International
- Glutathione Fine-Tunes the Innate Immune Response toward Antiviral Pathways in a Macrophage Cell Line Independently of Its Antioxidant Properties
- (2017) Marina Diotallevi et al. Frontiers in Immunology
- Negative Immune Regulator TIPE2 Promotes M2 Macrophage Differentiation through the Activation of PI3K-AKT Signaling Pathway
- (2017) Ruiling Liu et al. PLoS One
- Carbocisteine attenuates TNF-α-induced inflammation in human alveolar epithelial cells in vitro through suppressing NF-κB and ERK1/2 MAPK signaling pathways
- (2016) Wei Wang et al. ACTA PHARMACOLOGICA SINICA
- Dimethyl fumarate ameliorates dextran sulfate sodium-induced murine experimental colitis by activating Nrf2 and suppressing NLRP3 inflammasome activation
- (2016) Xiuting Liu et al. BIOCHEMICAL PHARMACOLOGY
- Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages
- (2016) Evanna L. Mills et al. CELL
- Reprogramming mitochondrial metabolism in macrophages as an anti-inflammatory signal
- (2016) Evanna L. Mills et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Curcumin and tetrahydrocurcumin both prevent osteoarthritis symptoms and decrease the expressions of pro-inflammatory cytokines in estrogen-deficient rats
- (2016) Sunmin Park et al. Genes and Nutrition
- IGF-I induces adipose derived mesenchymal cell chondrogenic differentiation in vitro and enhances chondrogenesis in vivo
- (2016) Quan Zhou et al. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
- NADPH Oxidases Are Essential for Macrophage Differentiation
- (2016) Qing Xu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis
- (2016) William H. Robinson et al. Nature Reviews Rheumatology
- IL-10 reduces apoptosis and extracellular matrix degradation after injurious compression of mature articular cartilage
- (2016) P. Behrendt et al. OSTEOARTHRITIS AND CARTILAGE
- Cartilage inflammation and degeneration is enhanced by pro-inflammatory (M1) macrophages in vitro , but not inhibited directly by anti-inflammatory (M2) macrophages
- (2016) L. Utomo et al. OSTEOARTHRITIS AND CARTILAGE
- Direct in vivo evidence of activated macrophages in human osteoarthritis
- (2016) V.B. Kraus et al. OSTEOARTHRITIS AND CARTILAGE
- Structural Biology and Evolution of the TGF-β Family
- (2016) Andrew P. Hinck et al. Cold Spring Harbor Perspectives in Biology
- Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription
- (2016) Eri H. Kobayashi et al. Nature Communications
- Resveratrol Interferes with IL1-β-Induced Pro-Inflammatory Paracrine Interaction between Primary Chondrocytes and Macrophages
- (2016) Emeric Limagne et al. Nutrients
- Curcumin and tetrahydrocurcumin both prevent osteoarthritis symptoms and decrease the expressions of pro-inflammatory cytokines in estrogen-deficient rats
- (2016) Sunmin Park et al. Genes and Nutrition
- The JAK-STAT Pathway: Impact on Human Disease and Therapeutic Intervention
- (2015) John J. O'Shea et al. Annual Review of Medicine
- Colony stimulating factor-1 receptor signaling networks inhibit mouse macrophage inflammatory responses by induction of microRNA-21
- (2015) C. I. Caescu et al. BLOOD
- Quercetin: A flavonol with multifaceted therapeutic applications?
- (2015) Gabriele D'Andrea FITOTERAPIA
- Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization
- (2015) Abhishek K. Jha et al. IMMUNITY
- NZ suppresses TLR4/NF-κB signalings and NLRP3 inflammasome activation in LPS-induced RAW264.7 macrophages
- (2015) Pengjun Xiang et al. INFLAMMATION RESEARCH
- Chondrocyte Apoptosis in the Pathogenesis of Osteoarthritis
- (2015) Hyun Hwang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Osteoarthritis
- (2015) S Glyn-Jones et al. LANCET
- Arthritic and non-arthritic synovial fluids modulate IL10 and IL1RA gene expression in differentially activated primary human monocytes
- (2015) S. Lopa et al. OSTEOARTHRITIS AND CARTILAGE
- STAT1 deficiency redirects IFN signalling toward suppression of TLR response through a feedback activation of STAT3
- (2015) Hun Sik Kim et al. Scientific Reports
- Serum and Synovial Fluid Levels of CCL18 are Correlated with Radiographic Grading of Knee Osteoarthritis
- (2015) Guohui Yang MEDICAL SCIENCE MONITOR
- Regulation of Notch 1 signaling in THP-1 cells enhances M2 macrophage differentiation
- (2014) Reetu D. Singla et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Heme oxygenase-1 and anti-inflammatory M2 macrophages
- (2014) Yuji Naito et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Dimethyl fumarate protection against collagen II degradation
- (2014) Ye Li et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The role of macrophage phenotype in vascularization of tissue engineering scaffolds
- (2014) Kara L. Spiller et al. BIOMATERIALS
- Extrapineal melatonin: sources, regulation, and potential functions
- (2014) Darío Acuña-Castroviejo et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Nrf2 Knockout Attenuates the Anti-Inflammatory Effects of Phenethyl Isothiocyanate and Curcumin
- (2014) Sarandeep S. S. Boyanapalli et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Loss of NADPH Oxidase–Derived Superoxide Skews Macrophage Phenotypes to Delay Type 1 Diabetes
- (2014) Lindsey E. Padgett et al. DIABETES
- Transcription Factors NRF2 and NF-κB Are Coordinated Effectors of the Rho Family, GTP-binding Protein RAC1 during Inflammation
- (2014) Antonio Cuadrado et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Activation of a TGF- -Specific Multistep Gene Expression Program in Mature Macrophages Requires Glucocorticoid-Mediated Surface Expression of TGF- Receptor II
- (2014) A. Gratchev et al. JOURNAL OF IMMUNOLOGY
- Melatonin: a well-documented antioxidant with conditional pro-oxidant actions
- (2014) Hong-Mei Zhang et al. JOURNAL OF PINEAL RESEARCH
- TLR4 signalling in osteoarthritis—finding targets for candidate DMOADs
- (2014) Rodolfo Gómez et al. Nature Reviews Rheumatology
- Human osteoarthritic synovium impacts chondrogenic differentiation of mesenchymal stem cells via macrophage polarisation state
- (2014) N. Fahy et al. OSTEOARTHRITIS AND CARTILAGE
- TNF and MAP kinase signalling pathways
- (2014) Guadalupe Sabio et al. SEMINARS IN IMMUNOLOGY
- The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
- (2014) John D. Hayes et al. TRENDS IN BIOCHEMICAL SCIENCES
- Metabolic Reprograming in Macrophage Polarization
- (2014) Silvia Galván-Peña et al. Frontiers in Immunology
- Redox Control of Inflammation in Macrophages
- (2013) Bernhard Brüne et al. ANTIOXIDANTS & REDOX SIGNALING
- RXR Inhibits the NRF2-ARE Signaling Pathway through a Direct Interaction with the Neh7 Domain of NRF2
- (2013) H. Wang et al. CANCER RESEARCH
- Mesenchymal Stromal Cells: Sensors and Switchers of Inflammation
- (2013) Maria Ester Bernardo et al. Cell Stem Cell
- BTB and CNC Homolog 1 (Bach1) Deficiency Ameliorates TNBS Colitis in Mice
- (2013) Akihito Harusato et al. INFLAMMATORY BOWEL DISEASES
- Accelerated Development of Pulmonary Fibrosis via Cu,Zn-superoxide Dismutase-induced Alternative Activation of Macrophages
- (2013) Chao He et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- M2-like macrophages are responsible for collagen degradation through a mannose receptor–mediated pathway
- (2013) Daniel H. Madsen et al. JOURNAL OF CELL BIOLOGY
- CCL18 Activates Fibroblast-like Synoviocytes in Patients with Rheumatoid Arthritis
- (2013) A. TAKAYASU et al. JOURNAL OF RHEUMATOLOGY
- The epidemiology and impact of pain in osteoarthritis
- (2013) T. Neogi OSTEOARTHRITIS AND CARTILAGE
- The TSC-mTOR pathway regulates macrophage polarization
- (2013) Vanessa Byles et al. Nature Communications
- MafK positively regulates NF-κB activity by enhancing CBP-mediated p65 acetylation
- (2013) Yu-Jin Hwang et al. Scientific Reports
- Mesenchymal Stem Cells in Tissue Repair
- (2013) Amy M. DiMarino et al. Frontiers in Immunology
- Potential therapeutic effects of the simultaneous targeting of the Nrf2 and NF-κB pathways in diabetic neuropathy
- (2013) Veera Ganesh Yerra et al. Redox Biology
- IL-4 and IL-13 employ discrete signaling pathways for target gene expression in alternatively activated monocytes/macrophages
- (2012) Ashish Bhattacharjee et al. FREE RADICAL BIOLOGY AND MEDICINE
- Modulation of macrophage activation and programming in immunity
- (2012) Guangwei Liu et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Tumor associated macrophages and neutrophils in tumor progression
- (2012) Maria R. Galdiero et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Acanthopanax senticosus has a heme oxygenase-1 signaling-dependent effect on Porphyromonas gingivalis lipopolysaccharide-stimulated macrophages
- (2012) Hye Soo Kim et al. JOURNAL OF ETHNOPHARMACOLOGY
- Macrophage plasticity and polarization in tissue repair and remodelling
- (2012) Alberto Mantovani et al. JOURNAL OF PATHOLOGY
- Melatonin modulates TLR4-mediated inflammatory genes through MyD88- and TRIF-dependent signaling pathways in lipopolysaccharide-stimulated RAW264.7 cells
- (2012) Mi-Zhen Xia et al. JOURNAL OF PINEAL RESEARCH
- Structural and Functional Characterization of Nrf2 Degradation by the Glycogen Synthase Kinase 3/ -TrCP Axis
- (2012) P. Rada et al. MOLECULAR AND CELLULAR BIOLOGY
- USP15 stabilizes TGF-β receptor I and promotes oncogenesis through the activation of TGF-β signaling in glioblastoma
- (2012) Pieter J A Eichhorn et al. NATURE MEDICINE
- Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization
- (2012) A. Arranz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Plasma proteins present in osteoarthritic synovial fluid can stimulate cytokine production via Toll-like receptor 4
- (2012) Dong Sohn et al. ARTHRITIS RESEARCH & THERAPY
- MAP Kinase Pathways
- (2012) D. K. Morrison Cold Spring Harbor Perspectives in Biology
- Regulation of Macrophage Polarization and Wound Healing
- (2012) Christopher J. Ferrante et al. Advances in Wound Care
- Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway
- (2011) Ralf A. Linker et al. BRAIN
- Nuclear factor p65 interacts with Keap1 to repress the Nrf2-ARE pathway
- (2011) Miao Yu et al. CELLULAR SIGNALLING
- Activation of stress signaling pathways by electrophilic oxidized and nitrated lipids
- (2011) Emilia Kansanen et al. FREE RADICAL BIOLOGY AND MEDICINE
- Molecular Mechanism for Adiponectin-dependent M2 Macrophage Polarization
- (2011) Palash Mandal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TNF Mediates the Sustained Activation of Nrf2 in Human Monocytes
- (2011) S. A. Rushworth et al. JOURNAL OF IMMUNOLOGY
- IGF-1 and PDGF-bb Suppress IL-1β-Induced Cartilage Degradation through Down-Regulation of NF-κB Signaling: Involvement of Src/PI-3K/AKT Pathway
- (2011) Azadeh Montaseri et al. PLoS One
- Prostaglandin E2 induces interleukin-6 expression in human chondrocytes via cAMP/protein kinase A- and phosphatidylinositol 3-kinase-dependent NF-κB activation
- (2010) Pu Wang et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Cancer Chemoprevention Mechanisms Mediated Through the Keap1–Nrf2 Pathway
- (2010) John D. Hayes et al. ANTIOXIDANTS & REDOX SIGNALING
- The role of synovial macrophages and macrophage-produced mediators in driving inflammatory and destructive responses in osteoarthritis
- (2010) Jan Bondeson et al. ARTHRITIS AND RHEUMATISM
- Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential
- (2010) Ananta Paine et al. BIOCHEMICAL PHARMACOLOGY
- Expression of heme oxygenase-1 in human leukemic cells and its regulation by transcriptional repressor Bach1
- (2010) Takuya Miyazaki et al. CANCER SCIENCE
- Role of proinflammatory cytokines in the pathophysiology of osteoarthritis
- (2010) Mohit Kapoor et al. Nature Reviews Rheumatology
- Modification of osteoarthritis in the guinea pig with pulsed low-intensity ultrasound treatment
- (2010) I. Gurkan et al. OSTEOARTHRITIS AND CARTILAGE
- The Inflammasomes: Guardians of the Body
- (2009) Fabio Martinon et al. Annual Review of Immunology
- Notch1 upregulates LPS-induced macrophage activation by increasing NF-κB activity
- (2009) Eva Monsalve et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Prolonged cigarette smoke exposure decreases heme oxygenase-1 and alters Nrf2 and Bach1 expression in human macrophages: Roles of the MAP kinases ERK1/2and JNK
- (2009) D. Goven et al. FEBS LETTERS
- The role of c-Jun phosphorylation in EpRE activation of phase II genes
- (2009) Smadar Levy et al. FREE RADICAL BIOLOGY AND MEDICINE
- The anti-inflammatory effects of adiponectin are mediated via a heme oxygenase-1-dependent pathway in rat Kupffer cells
- (2009) Palash Mandal et al. HEPATOLOGY
- Regulation of interferon and Toll-like receptor signaling during macrophage activation by opposing feedforward and feedback inhibition mechanisms
- (2009) Xiaoyu Hu et al. IMMUNOLOGICAL REVIEWS
- Increase in ALK1/ALK5 Ratio as a Cause for Elevated MMP-13 Expression in Osteoarthritis in Humans and Mice
- (2009) E. N. Blaney Davidson et al. JOURNAL OF IMMUNOLOGY
- Heme Oxygenase-1 Contributes to an Alternative Macrophage Activation Profile Induced by Apoptotic Cell Supernatants
- (2009) Nicole Weis et al. MOLECULAR BIOLOGY OF THE CELL
- KEAP1 E3 Ligase-Mediated Downregulation of NF-κB Signaling by Targeting IKKβ
- (2009) Dung-Fang Lee et al. MOLECULAR CELL
- Platelet-Derived Growth Factor BB Mediates the Tropism of Human Mesenchymal Stem Cells for Malignant Gliomas
- (2009) Nobuhiro Hata et al. NEUROSURGERY
- Alternative Activation of Macrophages: An Immunologic Functional Perspective
- (2008) Fernando O. Martinez et al. Annual Review of Immunology
- NF-κB/p65 antagonizes Nrf2-ARE pathway by depriving CBP from Nrf2 and facilitating recruitment of HDAC3 to MafK
- (2008) Guang-Hui Liu et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Regulation of TGF-β family signaling by E3 ubiquitin ligases
- (2008) Yasumichi Inoue et al. CANCER SCIENCE
- Innate immune system activation in osteoarthritis: is osteoarthritis a chronic wound?
- (2008) Carla R Scanzello et al. CURRENT OPINION IN RHEUMATOLOGY
- IL-10 overexpression differentially affects cartilage matrix gene expression in response to TNF-α in human articular chondrocytes in vitro
- (2008) R.D. Müller et al. CYTOKINE
- IGF-1 regulation of type II collagen and MMP-13 expression in rat endplate chondrocytes via distinct signaling pathways
- (2008) M. Zhang et al. OSTEOARTHRITIS AND CARTILAGE
- Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema
- (2008) D Goven et al. THORAX
- Notch signaling is activated by TLR stimulation and regulates macrophage functions
- (2007) Tanapat Palaga et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Macrophage activation and polarization
- (2007) Fernando Oneissi Martinez Frontiers in Bioscience-Landmark
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now