When healing turns into killing – the pathophysiology of pancreatic and hepatic fibrosis
出版年份 2022 全文链接
标题
When healing turns into killing – the pathophysiology of pancreatic and hepatic fibrosis
作者
关键词
-
出版物
JOURNAL OF PHYSIOLOGY-LONDON
Volume 600, Issue 11, Pages 2579-2612
出版商
Wiley
发表日期
2022-04-18
DOI
10.1113/jp281135
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- CRISPR-Cas9 screen identifies oxidative phosphorylation as essential for cancer cell survival at low extracellular pH
- (2022) Johanna Michl et al. Cell Reports
- Monocarboxylate Transporters Are Involved in Extracellular Matrix Remodelling in Pancreatic Ductal Adenocarcinoma
- (2022) Ayşe Ufuk et al. Cancers
- Deletion of Mcpip1 in Mcpip1fl/flAlbCre mice recapitulates the phenotype of human primary biliary cholangitis
- (2021) Jerzy Kotlinowski et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASH
- (2021) Jinrui Dong et al. Nature Communications
- Fibroblast cells reveal their ancestry
- (2021) Christopher D. Buckley NATURE
- The Roles of Calcium and ATP in the Physiology and Pathology of the Exocrine Pancreas
- (2021) Ole H. Petersen et al. PHYSIOLOGICAL REVIEWS
- Cellular Mechanisms of Liver Fibrosis
- (2021) Pragyan Acharya et al. Frontiers in Pharmacology
- Salidroside Inhibits CCl4-Induced Liver Fibrosis in Mice by Reducing Activation and Migration of HSC Induced by Liver Sinusoidal Endothelial Cell-Derived Exosomal SphK1
- (2021) Qiannan Ye et al. Frontiers in Pharmacology
- Adipocyte Fatty Acid Binding Protein Promotes the Onset and Progression of Liver Fibrosis via Mediating the Crosstalk between Liver Sinusoidal Endothelial Cells and Hepatic Stellate Cells
- (2021) Xiaoping Wu et al. Advanced Science
- Matrix stiffness and its influence on pancreatic diseases
- (2021) Weifan Zhang et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Co-encapsulation of collagenase type I and silibinin in chondroitin sulfate coated multilayered nanoparticles for targeted treatment of liver fibrosis
- (2021) Jingwen Luo et al. CARBOHYDRATE POLYMERS
- CYP2E1 in Alcoholic and Non-Alcoholic Liver Injury. Roles of ROS, Reactive Intermediates and Lipid Overload
- (2021) Riina Harjumäki et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Pancreatic Cancer
- (2021) Wungki Park et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Fasudil prevents liver fibrosis via activating natural killer cells and suppressing hepatic stellate cells
- (2021) Qiu-Ju Han et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Single-cell RNA-seq reveals fibroblast heterogeneity and increased mesenchymal fibroblasts in human fibrotic skin diseases
- (2021) Cheng-Cheng Deng et al. Nature Communications
- Stromal hyaluronan accumulation is associated with low immune response and poor prognosis in pancreatic cancer
- (2021) Kyösti Tahkola et al. Scientific Reports
- Tumor stiffening reversion through collagen crosslinking inhibition improves T cell migration and anti-PD-1 treatment
- (2021) Alba Nicolas-Boluda et al. eLife
- Stiffness is associated with hepatic stellate cell heterogeneity during liver fibrosis
- (2021) Enis Kostallari et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Nicotine facilitates pancreatic fibrosis by promoting activation of pancreatic stellate cells via α7nAChR-mediated JAK2/STAT3 signaling pathway in rats
- (2021) Zhiren Li et al. TOXICOLOGY LETTERS
- Silymarin as Supportive Treatment in Liver Diseases: A Narrative Review
- (2020) Anton Gillessen et al. ADVANCES IN THERAPY
- ROS in cancer therapy: the bright side of the moon
- (2020) Bruno Perillo et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Mechanisms of Fibrosis Development in NASH
- (2020) Robert F. Schwabe et al. GASTROENTEROLOGY
- Inflammation and fibrosis in chronic liver diseases including non-alcoholic fatty liver disease and hepatitis C
- (2020) Sudeep Tanwar et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Protonation of Piezo1 Impairs Cell-Matrix Interactions of Pancreatic Stellate Cells
- (2020) Anna Kuntze et al. Frontiers in Physiology
- Signaling in the Physiology and Pathophysiology of Pancreatic Stellate Cells – a Brief Review of Recent Advances
- (2020) Agnieszka A. Kusiak et al. Frontiers in Physiology
- Islet pericytes convert into profibrotic myofibroblasts in a mouse model of islet vascular fibrosis
- (2020) Luciana Mateus Gonçalves et al. DIABETOLOGIA
- Evaluation of liver fibrosis in patients with Wilson’s disease
- (2020) Adam Przybyłkowski et al. EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
- Pancreatic Cancer and Its Microenvironment—Recent Advances and Current Controversies
- (2020) Kinga B. Stopa et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- TGF-β1 secreted by pancreatic stellate cells promotes stemness and tumourigenicity in pancreatic cancer cells through L1CAM downregulation
- (2020) Donatella Delle Cave et al. ONCOGENE
- Hepatocyte mitochondria-derived danger signals directly activate hepatic stellate cells and drive progression of liver fibrosis
- (2020) Ping An et al. Nature Communications
- Liver Fibrosis: Mechanistic Concepts and Therapeutic Perspectives
- (2020) Natascha Roehlen et al. Cells
- Human Pluripotent Stem Cell-Derived Organoids as Models of Liver Disease
- (2020) Muhammad Nadzim Bin Ramli et al. GASTROENTEROLOGY
- Randomized Phase III Trial of Pegvorhyaluronidase Alfa With Nab-Paclitaxel Plus Gemcitabine for Patients With Hyaluronan-High Metastatic Pancreatic Adenocarcinoma
- (2020) Eric Van Cutsem et al. JOURNAL OF CLINICAL ONCOLOGY
- Chronic pancreatitis
- (2020) Georg Beyer et al. LANCET
- Liver regeneration: biological and pathological mechanisms and implications
- (2020) George K. Michalopoulos et al. Nature Reviews Gastroenterology & Hepatology
- Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination
- (2020) Lars Muhl et al. Nature Communications
- Electron paramagnetic resonance spectroscopy reveals alterations in the redox state of endogenous copper and iron complexes in photodynamic stress-induced ischemic mouse liver
- (2020) Monika A. Jakubowska et al. Redox Biology
- Role of Exocrine and Endocrine Insufficiency in the Management of Patients with Chronic Pancreatitis
- (2020) Carmelo Diéguez-Castillo et al. Journal of Clinical Medicine
- Cell Therapy for Advanced Liver Diseases: Repair or Rebuild
- (2020) Benjamin J. Dwyer et al. JOURNAL OF HEPATOLOGY
- Acute pancreatitis
- (2020) Lotte Boxhoorn et al. LANCET
- Persistent recovery of pancreatic function in patients with cystic fibrosis after ivacaftor
- (2020) Danielle Munce et al. PEDIATRIC PULMONOLOGY
- Phase I clinical trial repurposing all-trans retinoic acid as a stromal targeting agent for pancreatic cancer
- (2020) Hemant M. Kocher et al. Nature Communications
- Stroma-Targeting Therapy in Pancreatic Cancer: One Coin With Two Sides?
- (2020) Bolun Jiang et al. Frontiers in Oncology
- Notch in mechanotransduction – from molecular mechanosensitivity to tissue mechanostasis
- (2020) Oscar M. J. A. Stassen et al. JOURNAL OF CELL SCIENCE
- Fibrosis: from mechanisms to medicines
- (2020) Neil C. Henderson et al. NATURE
- Experimental Acute Pancreatitis Models: History, Current Status, and Role in Translational Research
- (2020) Xinmin Yang et al. Frontiers in Physiology
- Tumor-stromal crosstalk in pancreatic cancer and tissue fibrosis
- (2019) Divya Thomas et al. Molecular Cancer
- The therapeutic potential of induced hepatocyte-like cells generated by direct reprogramming on hepatic fibrosis
- (2019) Suhyun Park et al. Stem Cell Research & Therapy
- Interaction Mechanisms Between the NOX4/ROS and RhoA/ROCK1 Signaling Pathways as New Anti- fibrosis Targets of Ursolic Acid in Hepatic Stellate Cells
- (2019) Chenkai Huang et al. Frontiers in Pharmacology
- ERK Pathway in Activated, Myofibroblast-Like, Hepatic Stellate Cells: A Critical Signaling Crossroad Sustaining Liver Fibrosis
- (2019) Beatrice Foglia et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- siRNA- and miRNA-based therapeutics for liver fibrosis
- (2019) Zhen Zhao et al. Translational Research
- Targeting TGF βR2‐mutant tumors exposes vulnerabilities to stromal TGF β blockade in pancreatic cancer
- (2019) Huocong Huang et al. EMBO Molecular Medicine
- Mechanotransduction in Liver Diseases
- (2019) Ningling Kang SEMINARS IN LIVER DISEASE
- A mechanism for the activation of the mechanosensitive Piezo1 channel by the small molecule Yoda1
- (2019) Wesley M. Botello-Smith et al. Nature Communications
- Association between Smoking and Liver Fibrosis among Patients with Nonalcoholic Fatty Liver Disease
- (2019) Hongjie Ou et al. Canadian Journal of Gastroenterology and Hepatology
- Mechanisms Underlying Hepatitis C Virus-Associated Hepatic Fibrosis
- (2019) Mousumi Khatun et al. Cells
- TGF-β in Hepatic Stellate Cell Activation and Liver Fibrogenesis—Updated 2019
- (2019) Dewidar et al. Cells
- Pancreatic stellate cells in the islets as a novel target to preserve the pancreatic β‐cell mass and function
- (2019) Yeoree Yang et al. Journal of Diabetes Investigation
- Yes-Associated Protein 1 Plays Major Roles in Pancreatic Stellate Cell Activation and Fibroinflammatory Responses
- (2019) Cheng Hu et al. Frontiers in Physiology
- Activin-A causes Hepatic stellate cell activation via the induction of TNFα and TGFβ in Kupffer cells
- (2018) Foteini Kiagiadaki et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Generation of Hepatic Stellate Cells from Human Pluripotent Stem Cells Enables In Vitro Modeling of Liver Fibrosis
- (2018) Mar Coll et al. Cell Stem Cell
- HMGB1-induced autophagy facilitates hepatic stellate cells activation: a new pathway in liver fibrosis
- (2018) Jing Li et al. CLINICAL SCIENCE
- A novel flow cytometry tool for fibrosis scoring through hepatic stellate cell differentiation
- (2018) Johnny Amer et al. CYTOMETRY PART A
- Acute Pancreatitis and Pancreatic Cancer Risk: A Nationwide Matched-Cohort Study in Denmark
- (2018) Jakob Kirkegård et al. GASTROENTEROLOGY
- Mechanosensing and fibrosis
- (2018) Daniel J. Tschumperlin et al. JOURNAL OF CLINICAL INVESTIGATION
- Resveratrol Inhibits ROS-Promoted Activation and Glycolysis of Pancreatic Stellate Cells via Suppression of miR-21
- (2018) Bin Yan et al. Oxidative Medicine and Cellular Longevity
- Pathogenesis of non-alcoholic fatty liver disease in children and adolescence: From “two hit theory” to “multiple hit model”
- (2018) Yan-Lan Fang et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Fibroblast-to-myofibroblast transition in bronchial asthma
- (2018) Marta Michalik et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- CXCL6-EGFR-induced Kupffer cells secrete TGF-β1 promoting hepatic stellate cell activation via the SMAD2/BRD4/C-MYC/EZH2 pathway in liver fibrosis
- (2018) Xiaobo Cai et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- IVACAFTOR restores FGF19 regulated bile acid homeostasis in cystic fibrosis patients with an S1251N or a G551D gating mutation
- (2018) Ivo P. van de Peppel et al. Journal of Cystic Fibrosis
- Alcoholic liver disease
- (2018) Helmut K. Seitz et al. Nature Reviews Disease Primers
- Carvedilol attenuates liver fibrosis by suppressing autophagy and promoting apoptosis in hepatic stellate cells
- (2018) Dongxiao Meng et al. BIOMEDICINE & PHARMACOTHERAPY
- The renin-angiotensin system as a target to solve the riddle of endocrine pancreas homeostasis
- (2018) Francielle Graus-Nunes et al. BIOMEDICINE & PHARMACOTHERAPY
- GPER is a mechanoregulator of pancreatic stellate cells and the tumor microenvironment
- (2018) Ernesto Cortes et al. EMBO REPORTS
- Substance P Promotes Liver Sinusoidal Endothelium-Mediated Hepatic Regeneration by NO/HGF Regulation
- (2018) Jiyuan Piao et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Wound Healing: A Cellular Perspective
- (2018) Melanie Rodrigues et al. PHYSIOLOGICAL REVIEWS
- Cystic Fibrosis of the Pancreas: The Role of CFTR Channel in the Regulation of Intracellular Ca2+ Signaling and Mitochondrial Function in the Exocrine Pancreas
- (2018) Tamara Madácsy et al. Frontiers in Physiology
- Methyl ferulic acid attenuates liver fibrosis and hepatic stellate cell activation through the TGF-β1/Smad and NOX4/ROS pathways
- (2018) Qi Cheng et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Hepatitis C virus-induced CCL5 secretion from macrophages activates hepatic stellate cells
- (2017) Reina Sasaki et al. HEPATOLOGY
- Nanoparticles for the treatment of liver fibrosis
- (2017) Suchithra Poilil Surendran et al. International Journal of Nanomedicine
- Brazilian guidelines for the diagnosis and treatment of cystic fibrosis
- (2017) Rodrigo Abensur Athanazio et al. Jornal Brasileiro de Pneumologia
- Metabolic syndrome and severity of fibrosis in nonalcoholic fatty liver disease: An age-dependent risk profiling study
- (2017) Salvatore Petta et al. LIVER INTERNATIONAL
- Role and regulation of autophagy and apoptosis by nitric oxide in hepatic stellate cells during acute liver failure
- (2017) Li Jin et al. LIVER INTERNATIONAL
- Human hepatocyte transplantation for liver disease: current status and future perspectives
- (2017) V Iansante et al. PEDIATRIC RESEARCH
- Biology of pancreatic stellate cells—more than just pancreatic cancer
- (2017) Pawel E. Ferdek et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- TRPC6 channels modulate the response of pancreatic stellate cells to hypoxia
- (2017) Nikolaj Nielsen et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- The Impact of Renin-Angiotensin System Blockade on Renal Outcomes and Mortality in Pre-Dialysis Patients with Advanced Chronic Kidney Disease
- (2017) Yun Jung Oh et al. PLoS One
- Roles of pH and the Na + /H + exchanger NHE1 in cancer: From cell biology and animal models to an emerging translational perspective?
- (2017) Christian Stock et al. SEMINARS IN CANCER BIOLOGY
- Cardiovascular consequences of metabolic syndrome
- (2017) Johnathan D. Tune et al. Translational Research
- Efficacy and safety of pancreatic enzyme replacement therapy on exocrine pancreatic insufficiency: a meta-analysis
- (2017) Can Gan et al. Oncotarget
- Inhibition of Jak/STAT signaling reduces the activation of pancreatic stellate cells in vitro and limits caerulein-induced chronic pancreatitis in vivo
- (2017) Hannah M. Komar et al. Scientific Reports
- Substrate Rigidity Controls Activation and Durotaxis in Pancreatic Stellate Cells
- (2017) Dariusz Lachowski et al. Scientific Reports
- Calcium signalling in pancreatic stellate cells: Mechanisms and potential roles
- (2016) Oleksiy Gryshchenko et al. CELL CALCIUM
- Medical and Surgical Treatment Options for Nonalcoholic Steatohepatitis
- (2016) Kathleen E. Corey et al. DIGESTIVE DISEASES AND SCIENCES
- Role of TRPC1 channels in pressure-mediated activation of murine pancreatic stellate cells
- (2016) Benedikt Fels et al. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
- Beyond pancreatic insufficiency and liver disease in cystic fibrosis
- (2016) Stephanie Demeyer et al. EUROPEAN JOURNAL OF PEDIATRICS
- Isolation and characterization of human islet stellate cells
- (2016) Min Zha et al. EXPERIMENTAL CELL RESEARCH
- Targeting the renin–angiotensin system in liver fibrosis
- (2016) Pau Sancho-Bru et al. Hepatology International
- Hepatic expression of Sonic Hedgehog induces liver fibrosis and promotes hepatocarcinogenesis in a transgenic mouse model
- (2016) Sook In Chung et al. JOURNAL OF HEPATOLOGY
- Transplantation of a human iPSC-derived hepatocyte sheet increases survival in mice with acute liver failure
- (2016) Yasuhito Nagamoto et al. JOURNAL OF HEPATOLOGY
- Bile acids induce necrosis in pancreatic stellate cells dependent on calcium entry and sodium-driven bile uptake
- (2016) Pawel E. Ferdek et al. JOURNAL OF PHYSIOLOGY-LONDON
- Bile as a key aetiological factor of acute but not chronic pancreatitis: a possible theory revealed
- (2016) Péter Hegyi JOURNAL OF PHYSIOLOGY-LONDON
- Clinical Advancements in the Targeted Therapies against Liver Fibrosis
- (2016) Ruchi Bansal et al. MEDIATORS OF INFLAMMATION
- The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)
- (2016) Elena Buzzetti et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Diabetes Mellitus Is Associated With an Exocrine Pancreatopathy
- (2016) Sonmoon Mohapatra et al. PANCREAS
- Pancreatic stellate cells regulate blood vessel density in the stroma of pancreatic ductal adenocarcinoma
- (2016) Francesco Di Maggio et al. PANCREATOLOGY
- Oriented collagen fibers direct tumor cell intravasation
- (2016) Weijing Han et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Anti-viral role of toll like receptor 4 in hepatitis B virus infection: An in vitro study
- (2016) Dipanwita Das et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Metabolic alterations and hepatitis C: From bench to bedside
- (2016) Ming-Ling Chang WORLD JOURNAL OF GASTROENTEROLOGY
- MicroRNA-378 limits activation of hepatic stellate cells and liver fibrosis by suppressing Gli3 expression
- (2016) Jeongeun Hyun et al. Nature Communications
- ATRA mechanically reprograms pancreatic stellate cells to suppress matrix remodelling and inhibit cancer cell invasion
- (2016) Antonios Chronopoulos et al. Nature Communications
- IFN and CCL2 Cooperate to Redirect Tumor-Infiltrating Monocytes to Degrade Fibrosis and Enhance Chemotherapy Efficacy in Pancreatic Carcinoma
- (2016) K. B. Long et al. Cancer Discovery
- HCV derived from sera of HCV-infected patients induces pro-fibrotic effects in human primary fibroblasts by activating GLI2
- (2016) M. Granato et al. Scientific Reports
- Skin fibrosis: Models and mechanisms
- (2016) N.N. Do et al. Current Research in Translational Medicine
- Characterization of the MMP/TIMP Imbalance and Collagen Production Induced by IL-1β or TNF-α Release from Human Hepatic Stellate Cells
- (2016) Sacha Robert et al. PLoS One
- Suppression of ROS Production by Exendin-4 in PSC Attenuates the High Glucose-Induced Islet Fibrosis
- (2016) Ji-Won Kim et al. PLoS One
- Involvement of Pancreatic Stellate Cells in Regeneration of Remnant Pancreas after Partial Pancreatectomy
- (2016) Shigenori Ota et al. PLoS One
- Stiffening hydrogels for investigating the dynamics of hepatic stellate cell mechanotransduction during myofibroblast activation
- (2016) Steven R. Caliari et al. Scientific Reports
- Experimental models of liver fibrosis
- (2015) Sara Crespo Yanguas et al. ARCHIVES OF TOXICOLOGY
- Desmoplasia in Primary Tumors and Metastatic Lesions of Pancreatic Cancer
- (2015) C. J. Whatcott et al. CLINICAL CANCER RESEARCH
- Antioxidant therapy for patients with chronic pancreatitis: A systematic review and meta-analysis
- (2015) Dongkai Zhou et al. CLINICAL NUTRITION
- Pancreatic stellate cell
- (2015) Minote Apte et al. CURRENT OPINION IN GASTROENTEROLOGY
- Frequency of Progression From Acute to Chronic Pancreatitis and Risk Factors: A Meta-analysis
- (2015) Sharanya J. Sankaran et al. GASTROENTEROLOGY
- Liver fibrosis occurs through dysregulation of MyD88-dependent innate B-cell activity
- (2015) Manoj Thapa et al. HEPATOLOGY
- Metabolic Reprogramming Is Required for Myofibroblast Contractility and Differentiation
- (2015) Karen Bernard et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural and functional hepatocyte polarity and liver disease
- (2015) Paul Gissen et al. JOURNAL OF HEPATOLOGY
- Kupffer Cells Support Hepatitis B Virus–Mediated CD8+T Cell Exhaustion via Hepatitis B Core Antigen–TLR2 Interactions in Mice
- (2015) Min Li et al. JOURNAL OF IMMUNOLOGY
- Pancreatic pathophysiology in cystic fibrosis
- (2015) Katherine N Gibson-Corley et al. JOURNAL OF PATHOLOGY
- Ca2+signals mediated by bradykinin type 2 receptors in normal pancreatic stellate cells can be inhibited by specific Ca2+channel blockade
- (2015) Oleksiy Gryshchenko et al. JOURNAL OF PHYSIOLOGY-LONDON
- Functions of Coenzyme Q10 Supplementation on Liver Enzymes, Markers of Systemic Inflammation, and Adipokines in Patients Affected by Nonalcoholic Fatty Liver Disease: A Double-Blind, Placebo-Controlled, Randomized Clinical Trial
- (2015) Farnaz Farsi et al. JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION
- Periductal stromal collagen topology of pancreatic ductal adenocarcinoma differs from that of normal and chronic pancreatitis
- (2015) Cole R Drifka et al. MODERN PATHOLOGY
- Inhibition of liver fibrosis using vitamin A-coupled liposomes to deliver matrix metalloproteinase-2 siRNA in vitro
- (2015) YIPING LI et al. Molecular Medicine Reports
- The role of fat and alcohol in acute pancreatitis: A dangerous liaison
- (2015) David N. Criddle PANCREATOLOGY
- Non-Canonical Wnt Predominates in Activated Rat Hepatic Stellate Cells, Influencing HSC Survival and Paracrine Stimulation of Kupffer Cells
- (2015) Laura Corbett et al. PLoS One
- The Use of Nanoparticles to Deliver Nitric Oxide to Hepatic Stellate Cells for Treating Liver Fibrosis and Portal Hypertension
- (2015) Hien T. T. Duong et al. Small
- Inhibition of IRS-1 by hepatitis C virus infection leads to insulin resistance in a PTEN-dependent manner
- (2015) Ting-ting Gao et al. Virology Journal
- Tumors: Wounds That Do Not Heal--Redux
- (2015) H. F. Dvorak Cancer Immunology Research
- Cancer-Stellate Cell Interactions Perpetuate the Hypoxia-Fibrosis Cycle in Pancreatic Ductal Adenocarcinoma
- (2015) Mert Erkan et al. NEOPLASIA
- Oral Coenzyme Q10 Supplementation in Patients with Nonalcoholic Fatty Liver Disease: Effects on Serum Vaspin, Chemerin, Pentraxin 3, Insulin Resistance and Oxidative Stress
- (2014) Mahdieh Abbasalizad Farhangi et al. ARCHIVES OF MEDICAL RESEARCH
- Acid-base transport in pancreatic cancer: Molecular mechanisms and clinical potential
- (2014) Su Chii Kong et al. Biochemistry and Cell Biology
- Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival
- (2014) Berna C. Özdemir et al. CANCER CELL
- Stromal Elements Act to Restrain, Rather Than Support, Pancreatic Ductal Adenocarcinoma
- (2014) Andrew D. Rhim et al. CANCER CELL
- Neutralizing Murine TGF R2 Promotes a Differentiated Tumor Cell Phenotype and Inhibits Pancreatic Cancer Metastasis
- (2014) K. T. Ostapoff et al. CANCER RESEARCH
- Crosstalk between fibroblasts and inflammatory cells
- (2014) S. Van Linthout et al. CARDIOVASCULAR RESEARCH
- Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy
- (2014) Mara H. Sherman et al. CELL
- Calcium signalling and secretory epithelia
- (2014) O.H. Petersen CELL CALCIUM
- Sonic Hedgehog Paracrine Signaling Activates Stromal Cells to Promote Perineural Invasion in Pancreatic Cancer
- (2014) X. Li et al. CLINICAL CANCER RESEARCH
- Prevailing Role of Contact Guidance in Intrastromal T-cell Trapping in Human Pancreatic Cancer
- (2014) N. Hartmann et al. CLINICAL CANCER RESEARCH
- High Mobility Group Box-1 (HMGB1) Participates in the Pathogenesis of Alcoholic Liver Disease (ALD)
- (2014) Xiaodong Ge et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The chemistry, physiology and pathology of pH in cancer
- (2014) P. Swietach et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Dimethyl Fumarate Protects Pancreatic Islet Cells and Non-Endocrine Tissue in L-Arginine-Induced Chronic Pancreatitis
- (2014) Lourdes Robles et al. PLoS One
- Hepatocyte Produced Matrix Metalloproteinases Are Regulated by CD147 in Liver Fibrogenesis
- (2014) Sarah R. Calabro et al. PLoS One
- Chronic hepatitis C and liver fibrosis
- (2014) Giada Sebastiani WORLD JOURNAL OF GASTROENTEROLOGY
- Isolation and characterization of islet stellate cells in rat
- (2014) Min Zha et al. Islets
- Silymarin coated gold nanoparticles ameliorates CCl4-induced hepatic injury and cirrhosis through down regulation of hepatic stellate cells and attenuation of Kupffer cells
- (2014) Nurul Kabir et al. RSC Advances
- Fibroblasts in fibrosis: novel roles and mediators
- (2014) Ryan T. Kendall et al. Frontiers in Pharmacology
- Prolonged high fat/alcohol exposure increases TRPV4 and its functional responses in pancreatic stellate cells
- (2013) L. P. Zhang et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Pancreas Organogenesis: From Lineage Determination to Morphogenesis
- (2013) Hung Ping Shih et al. Annual Review of Cell and Developmental Biology
- Reactive Oxygen Species in Inflammation and Tissue Injury
- (2013) Manish Mittal et al. ANTIOXIDANTS & REDOX SIGNALING
- Hepatitis C virus nonstructural protein 5A favors upregulation of gluconeogenic and lipogenic gene expression leading towards insulin resistance: a metabolic syndrome
- (2013) Fahed Parvaiz et al. ARCHIVES OF VIROLOGY
- Oxidative stress plays a role in high glucose-induced activation of pancreatic stellate cells
- (2013) Gyeong Ryul Ryu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The pathogenesis of cardiac fibrosis
- (2013) Ping Kong et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Newly diagnosed diabetes mellitus after acute pancreatitis: a systematic review and meta-analysis
- (2013) Stephanie L M Das et al. GUT
- Macrophage-secreted cytokines drive pancreatic acinar-to-ductal metaplasia through NF-κB and MMPs
- (2013) Geou-Yarh Liou et al. JOURNAL OF CELL BIOLOGY
- IFN-γ inhibits liver progenitor cell proliferation in HBV-infected patients and in 3,5-diethoxycarbonyl-1,4-dihydrocollidine diet-fed mice
- (2013) Hong-lei Weng et al. JOURNAL OF HEPATOLOGY
- Cytokine and Chemokine Responses in the Acute Phase of Hepatitis B Virus Replication in Naive and Previously Vaccinated Blood and Plasma Donors
- (2013) S. M. Keating et al. JOURNAL OF INFECTIOUS DISEASES
- Differential Serum Levels of Eosinophilic Eotaxins in Primary Sclerosing Cholangitis, Primary Biliary Cirrhosis, and Autoimmune Hepatitis
- (2013) Abdolamir Landi et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Hepatitis C Virus Induces Interleukin-1 (IL-1 )/IL-18 in Circulatory and Resident Liver Macrophages
- (2013) S. Shrivastava et al. JOURNAL OF VIROLOGY
- The role of protein synthesis and digestive enzymes in acinar cell injury
- (2013) Craig D. Logsdon et al. Nature Reviews Gastroenterology & Hepatology
- STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease
- (2013) J. Petrasek et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epithelial-to-mesenchymal transition predicts prognosis of pancreatic cancer
- (2013) Suguru Yamada et al. SURGERY
- Emerging concepts in pancreatic cancer medicine: targeting the tumor stroma
- (2013) Albrecht Neesse et al. OncoTargets and Therapy
- The Cystic Fibrosis of Exocrine Pancreas
- (2013) M. Wilschanski et al. Cold Spring Harbor Perspectives in Medicine
- Mass Spectrometry-based Quantitative Proteomic Profiling of Human Pancreatic and Hepatic Stellate Cell Lines
- (2013) Joao A. Paulo et al. GENOMICS PROTEOMICS & BIOINFORMATICS
- Ursodeoxycholic acid therapy in cystic fibrosis liver disease - a retrospective long-term follow-up case-control study
- (2012) M. Kappler et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Extracellular matrix degradation in liver fibrosis: Biochemistry and regulation
- (2012) John P. Iredale et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma
- (2012) Paolo P. Provenzano et al. CANCER CELL
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- (2010) A. Vonlaufen et al. GUT
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- (2010) Jong Hak Won et al. MOLECULAR BIOLOGY OF THE CELL
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