Salidroside Inhibits CCl4-Induced Liver Fibrosis in Mice by Reducing Activation and Migration of HSC Induced by Liver Sinusoidal Endothelial Cell-Derived Exosomal SphK1

Kadsura heteroclita stem ethanol extract protects against carbon tetrachloride-induced liver injury in mice via suppression of oxidative stress, inflammation, and apoptosis

(2020) Huang-he Yu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Inhibitory effects of nodakenin on inflammation and cell death in lipopolysaccharide-induced liver injury mice

(2020) Ji-Ye Lim et al.   PHYTOMEDICINE

Shedding Light on Extracellular Vesicle Biogenesis and Bioengineering

(2020) Fei Teng et al.   Advanced Science

The Role of S1P and the Related Signaling Pathway in the Development of Tissue Fibrosis

(2019) Erjin Wang et al.   Frontiers in Pharmacology

Salidroside represses proliferation, migration and invasion of human lung cancer cells through AKT and MEK/ERK signal pathway

(2019) Mei Ren et al.   Artificial Cells Nanomedicine and Biotechnology

Neuroprotective effect of salidroside against central nervous system inflammation-induced cognitive deficits: A pivotal role of sirtuin 1-dependent Nrf-2/HO-1/NF-κB pathway

(2019) Ning Xu et al.   PHYTOTHERAPY RESEARCH

Ameliorative effect of salidroside from Rhodiola Rosea L. on the gut microbiota subject to furan-induced liver injury in a mouse model

(2019) Yuan Yuan et al.   FOOD AND CHEMICAL TOXICOLOGY

The role of sphingosine kinase 2 in alcoholic liver disease

(2019) Eric K. Kwong et al.   DIGESTIVE AND LIVER DISEASE

Caspases in Cell Death, Inflammation, and Disease

(2019) Nina Van Opdenbosch et al.   IMMUNITY

Mitochondria as multifaceted regulators of cell death

(2019) Florian J. Bock et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

SPHK1 deficiency protects mice from acetaminophen-induced ER stress and mitochondrial permeability transition

(2019) Longjun Li et al.   CELL DEATH AND DIFFERENTIATION

Advances in anti hepatic fibrotic therapy with Traditional Chinese Medicine herbal formula

(2019) Hui Li   JOURNAL OF ETHNOPHARMACOLOGY

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Salidroside ameliorates autophagy and activation of hepatic stellate cells in mice via NF-κB and TGF-β1/Smad3 pathways

(2018) Jiao Feng et al.   Drug Design Development and Therapy

Apoptosis and necroptosis in the liver: a matter of life and death

(2018) Robert F. Schwabe et al.   Nature Reviews Gastroenterology & Hepatology

Salidroside Attenuates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease via AMPK-Dependent TXNIP/NLRP3 Pathway

(2018) Tao Zheng et al.   Oxidative Medicine and Cellular Longevity

Liver-Derived Exosomes and Their Implications in Liver Pathobiology

(2018) Sumi Sung et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Therapeutic use of curcumin-encapsulated and curcumin-primed exosomes

(2018) Mohammad N. Oskouie et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Salidroside protects rat liver against ischemia/reperfusion injury by regulating the GSK-3β/Nrf2-dependent antioxidant response and mitochondrial permeability transition

(2017) Linlin Cai et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Berberine protects HK-2 cells from hypoxia/reoxygenation induced apoptosis via inhibiting SPHK1 expression

(2017) Jianrao Lu et al.   Journal of Natural Medicines

Mechanisms of hepatic stellate cell activation

(2017) Takuma Tsuchida et al.   Nature Reviews Gastroenterology & Hepatology

Exosomes derived from palmitic acid-treated hepatocytes induce fibrotic activation of hepatic stellate cells

(2017) Young-Sun Lee et al.   Scientific Reports

An optimized method for mouse liver sinusoidal endothelial cell isolation

(2016) Jeremy Meyer et al.   EXPERIMENTAL CELL RESEARCH

Caspases Connect Cell-Death Signaling to Organismal Homeostasis

(2016) Lorenzo Galluzzi et al.   IMMUNITY

Sphingosine kinase-1, S1P transporter spinster homolog 2 and S1P2 mRNA expressions are increased in liver with advanced fibrosis in human

(2016) Masaya Sato et al.   Scientific Reports

Liver sinusoidal endothelial cells in hepatic fibrosis

(2015) Laurie D. DeLeve   HEPATOLOGY

Exosome Adherence and Internalization by Hepatic Stellate Cells Triggers Sphingosine 1-Phosphate-dependent Migration

(2015) Ruisi Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sphingosine kinase/sphingosine 1-phosphate (S1P)/S1P receptor axis is involved in liver fibrosis-associated angiogenesis

(2013) Le Yang et al.   JOURNAL OF HEPATOLOGY

Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy

(2013) Peter E. Czabotar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Effects of salidroside on exhaustive exercise-induced oxidative stress in rats

(2012) JIANSHENG XU et al.   Molecular Medicine Reports

Soluble Serum CD81 Is Elevated in Patients with Chronic Hepatitis C and Correlates with Alanine Aminotransferase Serum Activity

(2012) Martin-Walter Welker et al.   PLoS One

Pathogenesis of Liver Fibrosis

(2011) Virginia Hernandez-Gea et al.   Annual Review of Pathology-Mechanisms of Disease

Sample preparation method for isolation of single-cell types from mouse liver for proteomic studies

(2011) Wei Liu et al.   PROTEOMICS

Sphingosine 1-phosphate (S1P)/S1P receptors are involved in human liver fibrosis by action on hepatic myofibroblasts motility

(2010) Changyong Li et al.   JOURNAL OF HEPATOLOGY

The response of fenestrations, actin, and caveolin-1 to vascular endothelial growth factor in SK Hep1 cells

(2008) Victoria C. Cogger et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY