The chemistry, physiology and pathology of pH in cancer

Considering Protonation as a Posttranslational Modification Regulating Protein Structure and Function

(2013) André Schönichen et al.   Annual Review of Biophysics

Acidity Generated by the Tumor Microenvironment Drives Local Invasion

(2013) V. Estrella et al.   CANCER RESEARCH

Carbonic Anhydrase IX Promotes Tumor Growth and Necrosis In Vivo and Inhibition Enhances Anti-VEGF Therapy

(2012) A. McIntyre et al.   CLINICAL CANCER RESEARCH

Acid-extrusion from Tissue: The Interplay Between Membrane Transporters and pH Buffers

(2012) Alzbeta Hulikova et al.   CURRENT PHARMACEUTICAL DESIGN

Contribution of Na+,HCO3−-cotransport to cellular pH control in human breast cancer: A role for the breast cancer susceptibility locus NBCn1 (SLC4A7)

(2012) Ebbe Boedtkjer et al.   INTERNATIONAL JOURNAL OF CANCER

Regulation of intracellular pH in cancer cell lines under normoxia and hypoxia

(2012) Alzbeta Hulikova et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The Na+/H+ exchanger NHE1, but not the Na+, cotransporter NBCn1, regulates motility of MCF7 breast cancer cells expressing constitutively active ErbB2

(2011) Gitte Lauritzen et al.   CANCER LETTERS

Intrinsic CO2 Permeability of Cell Membranes and Potential Biological Relevance of CO2 Channels

(2011) Walter F. Boron et al.   CHEMPHYSCHEM

Dual Role of CO2/HCO3−Buffer in the Regulation of Intracellular pH of Three-dimensional Tumor Growths

(2011) Alzbeta Hulikova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interfering with pH regulation in tumours as a therapeutic strategy

(2011) Dario Neri et al.   NATURE REVIEWS DRUG DISCOVERY

Protons and Ca2+: Ionic Allies in Tumor Progression?

(2011) Maike Glitsch   PHYSIOLOGY

CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors

(2011) R. Le Floch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sharpey-Schafer Lecture: Gas channels

(2010) Walter F. Boron   EXPERIMENTAL PHYSIOLOGY

Hydrogen ion dynamics in human red blood cells

(2010) Pawel Swietach et al.   JOURNAL OF PHYSIOLOGY-LONDON

T Tubules and Surface Membranes Provide Equally Effective Pathways of Carbonic Anhydrase-Facilitated Lactic Acid Transport in Skeletal Muscle

(2010) Janine Hallerdei et al.   PLoS One

The Role of Carbonic Anhydrase 9 in Regulating Extracellular and Intracellular pH in Three-dimensional Tumor Cell Growths

(2009) Pawel Swietach et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Physiology of Cell Volume Regulation in Vertebrates

(2009) Else K. Hoffmann et al.   PHYSIOLOGICAL REVIEWS

Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX

(2009) V. Alterio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia-Inducible Carbonic Anhydrase IX and XII Promote Tumor Cell Growth by Counteracting Acidosis through the Regulation of the Intracellular pH

(2008) J. Chiche et al.   CANCER RESEARCH

Putative Re-entrant Loop 1 of AE2 Transmembrane Domain Has a Major Role in Acute Regulation of Anion Exchange by pH

(2008) Andrew K. Stewart et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tumor-associated Carbonic Anhydrase 9 Spatially Coordinates Intracellular pH in Three-dimensional Multicellular Growths

(2008) Pawel Swietach et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intracellular pH regulation in heart

(2008) Richard D. Vaughan-Jones et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Adaptation to hypoxia and acidosis in carcinogenesis and tumor progression

(2008) Jennifer S. Fang et al.   SEMINARS IN CANCER BIOLOGY

Measuring and Modeling Chloride-Hydroxyl Exchange in the Guinea-Pig Ventricular Myocyte

(2007) S.A. Niederer et al.   BIOPHYSICAL JOURNAL