High Mobility Group Box-1 (HMGB1) Participates in the Pathogenesis of Alcoholic Liver Disease (ALD)

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(2014) Daniel Antoine et al.   MOLECULAR MEDICINE

JAK/STAT1 signaling promotes HMGB1 hyperacetylation and nuclear translocation

(2014) B. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Osteopontin binding to lipopolysaccharide lowers tumor necrosis factor-α and prevents early alcohol-induced liver injury in mice

(2013) Xiaodong Ge et al.   HEPATOLOGY

Hepatocyte-specific high-mobility group box 1 deletion worsens the injury in liver ischemia/reperfusion: A role for intracellular high-mobility group box 1 in cellular protection

(2013) Hai Huang et al.   HEPATOLOGY

Protein phosphatase 2A dephosphorylates phosphoserines in nucleocytoplasmic shuttling and secretion of high mobility group box 1

(2013) Junichi Taira et al.   JOURNAL OF BIOCHEMISTRY

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(2013) Wei Li et al.   MOLECULAR MEDICINE

Mouse model of chronic and binge ethanol feeding (the NIAAA model)

(2013) Adeline Bertola et al.   Nature Protocols

Effect of Lipopolysaccharide Administration on the Number, Phenotype and Content of Nuclear Molecules in Blood Microparticles of Normal Human Subjects

(2013) A. Soop et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Regulation of HMGB1 release by inflammasomes

(2013) Ben Lu et al.   Protein & Cell

Arachidonic acid stimulates TNFα production in Kupffer cells via a reactive oxygen species-pERK1/2-Egr1-dependent mechanism

(2012) Francisco Javier Cubero et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

High mobility group box-1 is phosphorylated by protein kinase C zeta and secreted in colon cancer cells

(2012) Hanna Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

TLR activation regulates damage-associated molecular pattern isoforms released during pyroptosis

(2012) Sanna Nyström et al.   EMBO JOURNAL

Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release

(2012) Emilie Venereau et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity

(2012) Daniel J. Antoine et al.   JOURNAL OF HEPATOLOGY

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(2012) Huan Yang et al.   MOLECULAR MEDICINE

Novel role of PKR in inflammasome activation and HMGB1 release

(2012) Ben Lu et al.   NATURE

Argininosuccinate synthase conditions the response to acute and chronic ethanol-induced liver injury in mice

(2011) Tung Ming Leung et al.   HEPATOLOGY

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(2011) Hanna Schierbeck et al.   MOLECULAR MEDICINE

High Mobility Group Box 1 Release from Hepatocytes during Ischemia and Reperfusion Injury Is Mediated by Decreased Histone Deacetylase Activity

(2010) John Evankovich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inflammasome-Dependent Release of the Alarmin HMGB1 in Endotoxemia

(2010) M. Lamkanfi et al.   JOURNAL OF IMMUNOLOGY

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(2010) Daniel Antoine et al.   MOLECULAR MEDICINE

Interferon Regulatory Factor 1 Mediates Acetylation and Release of High Mobility Group Box 1 from Hepatocytes During Murine Liver Ischemia-Reperfusion Injury

(2010) Rajeev Dhupar et al.   SHOCK

The extracellular release of Schistosoma mansoni HMGB1 nuclear protein is mediated by acetylation

(2009) Vitor Coutinho Carneiro et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

NLRP3 (NALP3, Cryopyrin) Facilitates In Vivo Caspase-1 Activation, Necrosis, and HMGB1 Release via Inflammasome-Dependent and -Independent Pathways

(2009) S. B. Willingham et al.   JOURNAL OF IMMUNOLOGY

HMGB1 Is Phosphorylated by Classical Protein Kinase C and Is Secreted by a Calcium-Dependent Mechanism

(2009) Y. J. Oh et al.   JOURNAL OF IMMUNOLOGY

Non-histone nuclear factor HMGB1 is phosphorylated and secreted in colon cancers

(2009) Hyun Ju Kang et al.   LABORATORY INVESTIGATION

CD24 and Siglec-10 Selectively Repress Tissue Damage-Induced Immune Responses

(2009) G.-Y. Chen et al.   SCIENCE

High-Mobility Group Box-1 Protein and Keratin-18, Circulating Serum Proteins Informative of Acetaminophen-Induced Necrosis and Apoptosis In Vivo

(2009) Daniel J. Antoine et al.   TOXICOLOGICAL SCIENCES