The role of protein synthesis and digestive enzymes in acinar cell injury

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Unfolded protein response

(2012) Stewart Siyan Cao et al.   CURRENT BIOLOGY

Increased Activation of Hereditary Pancreatitis-associated Human Cationic Trypsinogen Mutants in Presence of Chymotrypsin C

(2012) András Szabó et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stress management at the ER: Regulators of ER stress-induced apoptosis

(2012) Adrienne M. Gorman et al.   PHARMACOLOGY & THERAPEUTICS

Tauroursodeoxycholic acid reduces endoplasmic reticulum stress, acinar cell damage, and systemic inflammation in acute pancreatitis

(2011) Ersin Seyhun et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The ER–mitochondria interface: The social network of cell death

(2011) Stefan Grimm   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Intra-acinar Trypsinogen Activation Mediates Early Stages of Pancreatic Injury but Not Inflammation in Mice With Acute Pancreatitis

(2011) Rajinder Dawra et al.   GASTROENTEROLOGY

Intracellular activation of trypsinogen in transgenic mice induces acute but not chronic pancreatitis

(2011) S. Gaiser et al.   GUT

The homocysteine-inducible endoplasmic reticulum (ER) stress protein Herp counteracts mutant α-synuclein-induced ER stress via the homeostatic regulation of ER-resident calcium release channel proteins

(2011) Cherine Belal et al.   HUMAN MOLECULAR GENETICS

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

Adaptive Unfolded Protein Response Attenuates Alcohol-Induced Pancreatic Damage

(2010) Aurelia Lugea et al.   GASTROENTEROLOGY

HSP72 Protects Cells from ER Stress-induced Apoptosis via Enhancement of IRE1α-XBP1 Signaling through a Physical Interaction

(2010) Sanjeev Gupta et al.   PLOS BIOLOGY

Ras Activity Levels Control the Development of Pancreatic Diseases

(2009) Baoan Ji et al.   GASTROENTEROLOGY

Hereditary pancreatitis caused by mutation-induced misfolding of human cationic trypsinogen: A novel disease mechanism

(2009) Éva Kereszturi et al.   HUMAN MUTATION

Intracellular Trypsin Induces Pancreatic Acinar Cell Death but Not NF-κB Activation

(2009) Baoan Ji et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

From endoplasmic-reticulum stress to the inflammatory response

(2008) Kezhong Zhang et al.   NATURE