标题
Regulating the discriminatory response to antigen by T-cell receptor
作者
关键词
-
出版物
BIOSCIENCE REPORTS
Volume 42, Issue 3, Pages -
出版商
Portland Press Ltd.
发表日期
2022-03-09
DOI
10.1042/bsr20212012
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The Cytokine Profiles and Immune Response Are Increased in COVID-19 Patients with Type 2 Diabetes Mellitus
- (2021) Mao Zheng et al. Journal of Diabetes Research
- PLCγ1 promotes phase separation of T cell signaling components
- (2021) Longhui Zeng et al. JOURNAL OF CELL BIOLOGY
- Fundamentals of T Cell Metabolism and Strategies to Enhance Cancer Immunotherapy
- (2021) Guillermo O. Rangel Rivera et al. Frontiers in Immunology
- Positive feedback between the T cell kinase Zap70 and its substrate LAT acts as a clustering-dependent signaling switch
- (2021) Elliot Dine et al. Cell Reports
- Allosteric activation of T cell antigen receptor signaling by quaternary structure relaxation
- (2021) Anna-Lisa Lanz et al. Cell Reports
- The discriminatory power of the T cell receptor
- (2021) Johannes Pettmann et al. eLife
- The Clinical Aspect of Adaptor Molecules in T Cell Signaling: Lessons Learnt From Inborn Errors of Immunity
- (2021) Yael Dinur-Schejter et al. Frontiers in Immunology
- Evolution of CD8+ T Cell Receptor (TCR) Engineered Therapies for the Treatment of Cancer
- (2021) Yimo Sun et al. Cells
- Novel ZAP-70-Related Immunodeficiency Presenting with Epstein–Barr Virus Lymphoproliferative Disorder and Hemophagocytic Lymphohistiocytosis
- (2021) Moriah Forster et al. Case Reports in Immunology
- CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity
- (2021) Lingyun Long et al. NATURE
- Differences in the dynamics of the tandem‐SH2 modules of the Syk and ZAP ‐70 tyrosine kinases
- (2021) Helen T. Hobbs et al. PROTEIN SCIENCE
- THEMIS-SHP1 Recruitment by 4-1BB Tunes LCK-Mediated Priming of Chimeric Antigen Receptor-Redirected T Cells
- (2020) Chuang Sun et al. CANCER CELL
- An allosteric hot spot in the tandem-SH2 domain of ZAP-70 regulates T-cell signaling
- (2020) Kaustav Gangopadhyay et al. BIOCHEMICAL JOURNAL
- Recent insights of T cell receptor-mediated signaling pathways for T cell activation and development
- (2020) Jeong-Ryul Hwang et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Metabolic signaling in T cells
- (2020) Justin A. Shyer et al. CELL RESEARCH
- Mechanisms determining a differential threshold for sensing Src family kinase activity by B and T cell antigen receptors
- (2020) Simon Borna et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent Axis
- (2020) Ana Campos Codo et al. Cell Metabolism
- Coreceptors and TCR Signaling – the Strong and the Weak of It
- (2020) Alexander M. Mørch et al. Frontiers in Cell and Developmental Biology
- Intrinsic Disorder in the T Cell Receptor Creates Cooperativity and Controls ZAP70 Binding
- (2020) Lara Clemens et al. BIOPHYSICAL JOURNAL
- Tyrosine 192 within the SH2 domain of the Src-protein tyrosine kinase p56Lck regulates T-cell activation independently of Lck/CD45 interactions
- (2020) Matthias Kästle et al. Cell Communication and Signaling
- Proofreading through spatial gradients
- (2020) Vahe Galstyan et al. eLife
- TCR microclusters form spatially segregated domains and sequentially assemble in calcium-dependent kinetic steps
- (2019) Jason Yi et al. Nature Communications
- T cell stemness and dysfunction in tumors are triggered by a common mechanism
- (2019) Suman Kumar Vodnala et al. SCIENCE
- Optogenetic control shows that kinetic proofreading regulates the activity of the T cell receptor
- (2019) O Sascha Yousefi et al. eLife
- Light-based tuning of ligand half-life supports kinetic proofreading model of T cell signaling
- (2019) Doug K Tischer et al. eLife
- Beyond TCR Signaling: Emerging Functions of Lck in Cancer and Immunotherapy
- (2019) Bommhardt et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- TCR–pMHC kinetics under force in a cell-free system show no intrinsic catch bond, but a minimal encounter duration before binding
- (2019) Laurent Limozin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Metabolic Dysregulations and Epigenetics: A Bidirectional Interplay that Drives Tumor Progression
- (2019) Crispo et al. Cells
- Structural basis of assembly of the human T cell receptor–CD3 complex
- (2019) De Dong et al. NATURE
- Slow phosphorylation of a tyrosine residue in LAT optimizes T cell ligand discrimination
- (2019) Wan-Lin Lo et al. NATURE IMMUNOLOGY
- Engineered T Cell Therapy for Cancer in the Clinic
- (2019) Lijun Zhao et al. Frontiers in Immunology
- Evolution of Alternative Adaptive Immune Systems in Vertebrates
- (2018) Thomas Boehm et al. Annual Review of Immunology
- ZAP-70 in Signaling, Biology, and Disease
- (2018) Byron B. Au-Yeung et al. Annual Review of Immunology
- Unraveling the Complex Interplay Between T Cell Metabolism and Function
- (2018) Ramon I. Klein Geltink et al. Annual Review of Immunology
- CAR T-cell Therapy: A New Era in Cancer Immunotherapy
- (2018) Miliotou N. Androulla et al. CURRENT PHARMACEUTICAL BIOTECHNOLOGY
- Human T Cell Development, Localization, and Function throughout Life
- (2018) Brahma V. Kumar et al. IMMUNITY
- TCR Signaling: Mechanisms of Initiation and Propagation
- (2018) Adam H. Courtney et al. TRENDS IN BIOCHEMICAL SCIENCES
- αβ T Cell Receptor Mechanosensing Forces out Serial Engagement
- (2018) Yinnian Feng et al. TRENDS IN IMMUNOLOGY
- A Stretch of Negatively Charged Amino Acids of Linker for Activation of T-Cell Adaptor Has a Dual Role in T-Cell Antigen Receptor Intracellular Signaling
- (2018) Mikel M. Arbulo-Echevarria et al. Frontiers in Immunology
- Store-Operated Ca 2+ Entry Controls Clonal Expansion of T Cells through Metabolic Reprogramming
- (2017) Martin Vaeth et al. IMMUNITY
- Mutations in linker for activation of T cells (LAT) lead to a novel form of severe combined immunodeficiency
- (2017) Chiara Bacchelli et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- A Phosphosite within the SH2 Domain of Lck Regulates Its Activation by CD45
- (2017) Adam H. Courtney et al. MOLECULAR CELL
- Encoding optical control in LCK kinase to quantitatively investigate its activity in live cells
- (2017) Ardiyanto Liaunardy-Jopeace et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Mechanosensing drives acuity ofαβT-cell recognition
- (2017) Yinnian Feng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- De novo phosphorylation and conformational opening of the tyrosine kinase Lck act in concert to initiate T cell receptor signaling
- (2017) Lars Philipsen et al. Science Signaling
- Tonic Signals: Why Do Lymphocytes Bother?
- (2017) Darienne R. Myers et al. TRENDS IN IMMUNOLOGY
- Encoding optical control in LCK kinase to quantitatively investigate its activity in live cells
- (2017) Ardiyanto Liaunardy-Jopeace et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Lck activation: puzzling the pieces together
- (2017) Luca Simeoni Oncotarget
- De novo phosphorylation and conformational opening of the tyrosine kinase Lck act in concert to initiate T cell receptor signaling
- (2017) Lars Philipsen et al. Science Signaling
- Metabolic Adaptation of Human CD4+ and CD8+ T-Cells to T-Cell Receptor-Mediated Stimulation
- (2017) Nicholas Jones et al. Frontiers in Immunology
- Cytotoxic T Cells Use Mechanical Force to Potentiate Target Cell Killing
- (2016) Roshni Basu et al. CELL
- Novel Mutation of ZAP-70-related Combined Immunodeficiency: First Case from the National Iranian Registry and Review of the Literature
- (2016) Afshin Shirkani et al. IMMUNOLOGICAL INVESTIGATIONS
- A novel human autoimmune syndrome caused by combined hypomorphic and activating mutations in ZAP-70
- (2016) Alice Y. Chan et al. JOURNAL OF EXPERIMENTAL MEDICINE
- SH2 Domains Serve as Lipid-Binding Modules for pTyr-Signaling Proteins
- (2016) Mi-Jeong Park et al. MOLECULAR CELL
- Ionic immune suppression within the tumour microenvironment limits T cell effector function
- (2016) Robert Eil et al. NATURE
- A cycle of Zap70 kinase activation and release from the TCR amplifies and disperses antigenic stimuli
- (2016) Zachary B Katz et al. NATURE IMMUNOLOGY
- Recruitment of calcineurin to the TCR positively regulates T cell activation
- (2016) Debjani Dutta et al. NATURE IMMUNOLOGY
- An electrostatic selection mechanism controls sequential kinase signaling downstream of the T cell receptor
- (2016) Neel H Shah et al. eLife
- Distinct Mechanisms Regulate Lck Spatial Organization in Activated T Cells
- (2016) Natasha Kapoor-Kaushik et al. Frontiers in Immunology
- Cytoskeletal forces during signaling activation in Jurkat T-cells
- (2015) King Lam Hui et al. MOLECULAR BIOLOGY OF THE CELL
- Genomic profiling of Sézary syndrome identifies alterations of key T cell signaling and differentiation genes
- (2015) Linghua Wang et al. NATURE GENETICS
- T cell receptor dwell times control the kinase activity of Zap70
- (2015) Christian Klammt et al. NATURE IMMUNOLOGY
- Signaling in Lymphocyte Activation
- (2015) Doreen Cantrell Cold Spring Harbor Perspectives in Biology
- The Structural Basis for Activation and Inhibition of ZAP-70 Kinase Domain
- (2015) Roland G. Huber et al. PLoS Computational Biology
- TCR Signaling in T Cell Memory
- (2015) Mark A. Daniels et al. Frontiers in Immunology
- Glucose Metabolism Regulates T Cell Activation, Differentiation, and Functions
- (2015) Clovis S. Palmer et al. Frontiers in Immunology
- Deconstructing the Peptide-MHC Specificity of T Cell Recognition
- (2014) Michael E. Birnbaum et al. CELL
- Coreceptor Scanning by the T Cell Receptor Provides a Mechanism for T Cell Tolerance
- (2014) Ondrej Stepanek et al. CELL
- The Glucose Transporter Glut1 Is Selectively Essential for CD4 T Cell Activation and Effector Function
- (2014) Andrew N. Macintyre et al. Cell Metabolism
- A THEMIS:SHP1 complex promotes T-cell survival
- (2014) W. Paster et al. EMBO JOURNAL
- The pool of preactivated Lck in the initiation of T-cell signaling: a critical re-evaluation of the Lck standby model
- (2014) Ondřej Ballek et al. IMMUNOLOGY AND CELL BIOLOGY
- Phosphatase CD45 Both Positively and Negatively Regulates T Cell Receptor Phosphorylation in Reconstituted Membrane Protein Clusters
- (2014) Gabriela Furlan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Glucose Uptake Is Limiting in T Cell Activation and Requires CD28-Mediated Akt-Dependent and Independent Pathways
- (2014) S. R. Jacobs et al. JOURNAL OF IMMUNOLOGY
- The signaling symphony: T cell receptor tunes cytokine-mediated T cell differentiation
- (2014) Weishan Huang et al. JOURNAL OF LEUKOCYTE BIOLOGY
- The self-obsession of T cells: how TCR signaling thresholds affect fate 'decisions' and effector function
- (2014) Kristin A Hogquist et al. NATURE IMMUNOLOGY
- Insights into the initiation of TCR signaling
- (2014) Arup K Chakraborty et al. NATURE IMMUNOLOGY
- CD28 and CD3 have complementary roles in T-cell traction forces
- (2014) Keenan T. Bashour et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fine-tuning T cell receptor signaling to control T cell development
- (2014) Guo Fu et al. TRENDS IN IMMUNOLOGY
- Metabolic Regulation of T Lymphocytes
- (2013) Nancie J. MacIver et al. Annual Review of Immunology
- The role of membrane rafts in Lck transport, regulation and signalling in T-cells
- (2013) Leandro N. Ventimiglia et al. BIOCHEMICAL JOURNAL
- TCR activation kinetics and feedback regulation in primary human T cells
- (2013) Mateusz Poltorak et al. Cell Communication and Signaling
- Cutting Edge: Cell Surface Linker for Activation of T Cells Is Recruited to Microclusters and Is Active in Signaling
- (2013) L. Balagopalan et al. JOURNAL OF IMMUNOLOGY
- Multipoint Binding of the SLP-76 SH2 Domain to ADAP Is Critical for Oligomerization of SLP-76 Signaling Complexes in Stimulated T Cells
- (2013) N. P. Coussens et al. MOLECULAR AND CELLULAR BIOLOGY
- Structural Basis for Activation of ZAP-70 by Phosphorylation of the SH2-Kinase Linker
- (2013) Q. Yan et al. MOLECULAR AND CELLULAR BIOLOGY
- Distinct TCR signaling pathways drive proliferation and cytokine production in T cells
- (2013) Clifford S Guy et al. NATURE IMMUNOLOGY
- Enhanced Function of Redirected Human T Cells Expressing Linker for Activation of T Cells That Is Resistant to Ubiquitylation
- (2012) Naoki Kunii et al. HUMAN GENE THERAPY
- Non-catalytic tyrosine-phosphorylated receptors
- (2012) Omer Dushek et al. IMMUNOLOGICAL REVIEWS
- Regulation of TCR signalling by tyrosine phosphatases: from immune homeostasis to autoimmunity
- (2012) Stephanie M. Stanford et al. IMMUNOLOGY
- Primary T-cell immunodeficiency with immunodysregulation caused by autosomal recessive LCK deficiency
- (2012) Fabian Hauck et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Fatty acyl chain-dependent but charge-independent association of the SH4 domain of Lck with lipid membranes
- (2012) Anoop Rawat et al. JOURNAL OF BIOSCIENCES
- Reduced TCR signaling potential impairs negative selection but does not result in autoimmune disease
- (2012) SuJin Hwang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Signaling Pathways That Regulate T Cell Development and Differentiation
- (2012) L. J. Berg JOURNAL OF IMMUNOLOGY
- Loss-of-function mutations within the IL-2 inducible kinase ITK in patients with EBV-associated lymphoproliferative diseases
- (2012) R M Linka et al. LEUKEMIA
- Evolution of innate and adaptive immune systems in jawless vertebrates
- (2012) Jun Kasamatsu MICROBIOLOGY AND IMMUNOLOGY
- LAT-Independent Erk Activation via Bam32-PLC-γ1-Pak1 Complexes: GTPase-Independent Pak1 Activation
- (2012) Alexandre K. Rouquette-Jazdanian et al. MOLECULAR CELL
- How does the kinase Lck phosphorylate the T cell receptor? Spatial organization as a regulatory mechanism
- (2012) Jérémie Rossy et al. Frontiers in Immunology
- The Serial Engagement Model 17 Years After: From TCR Triggering to Immunotherapy
- (2012) Salvatore Valitutti Frontiers in Immunology
- The integrin LFA-1 signals through ZAP-70 to regulate expression of high-affinity LFA-1 on T lymphocytes
- (2011) R. Evans et al. BLOOD
- T Cell Receptor Structures: Three for the Price of One
- (2011) Nicholas R.J. Gascoigne IMMUNITY
- T Cell Receptor Signaling Is Limited by Docking Geometry to Peptide-Major Histocompatibility Complex
- (2011) Jarrett J. Adams et al. IMMUNITY
- Fine-tuning of proximal TCR signaling by ZAP-70 tyrosine residues in Jurkat cells
- (2011) M. Szabo et al. INTERNATIONAL IMMUNOLOGY
- Molecular Mechanism of Selective Recruitment of Syk Kinases by the Membrane Antigen-Receptor Complex
- (2011) Peter J. Bond et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Subcellular Localization of Hexokinases I and II Directs the Metabolic Fate of Glucose
- (2011) Scott John et al. PLoS One
- Basic residues in the T-cell receptor cytoplasmic domain mediate membrane association and modulate signaling
- (2011) H. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Initiation of TCR Phosphorylation and Signal Transduction
- (2011) Nicholas R. J. Gascoigne et al. Frontiers in Immunology
- Mislocalization of Lck impairs thymocyte differentiation and can promote development of thymomas
- (2010) R. J. Salmond et al. BLOOD
- CD45-Csk Phosphatase-Kinase Titration Uncouples Basal and Inducible T Cell Receptor Signaling during Thymic Development
- (2010) Julie Zikherman et al. IMMUNITY
- Constitutively Active Lck Kinase in T Cells Drives Antigen Receptor Signal Transduction
- (2010) Konstantina Nika et al. IMMUNITY
- The biologic importance of tumor-infiltrating lymphocytes
- (2010) F. Stephen Hodi et al. JOURNAL OF CUTANEOUS PATHOLOGY
- Phospholipase Cγ1 is essential for T cell development, activation, and tolerance
- (2010) Guoping Fu et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Glutamine Uptake and Metabolism Are Coordinately Regulated by ERK/MAPK during T Lymphocyte Activation
- (2010) E. L. Carr et al. JOURNAL OF IMMUNOLOGY
- Induction of Glucose Metabolism in Stimulated T Lymphocytes Is Regulated by Mitogen-Activated Protein Kinase Signaling
- (2010) Aimee J. Marko et al. PLoS One
- CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery
- (2010) M. N. Artyomov et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ZAP-70: An Essential Kinase in T-cell Signaling
- (2010) H. Wang et al. Cold Spring Harbor Perspectives in Biology
- Structural Biology of the T-cell Receptor: Insights into Receptor Assembly, Ligand Recognition, and Initiation of Signaling
- (2010) K. W. Wucherpfennig et al. Cold Spring Harbor Perspectives in Biology
- T Cell Activation
- (2009) Jennifer E. Smith-Garvin et al. Annual Review of Immunology
- Insufficient Deactivation of the Protein Tyrosine Kinase Lck Amplifies T-Cell Responsiveness in Acute Coronary Syndrome
- (2009) Sergey Pryshchep et al. CIRCULATION RESEARCH
- Chemokine-Induced Zap70 Kinase-Mediated Dissociation of the Vav1-Talin Complex Activates α4β1 Integrin for T Cell Adhesion
- (2009) David García-Bernal et al. IMMUNITY
- The structure, regulation, and function of ZAP-70
- (2009) Byron B. Au-Yeung et al. IMMUNOLOGICAL REVIEWS
- Origin and evolution of the adaptive immune system: genetic events and selective pressures
- (2009) Martin F. Flajnik et al. NATURE REVIEWS GENETICS
- B lymphocytes: how they develop and function
- (2008) T. W. LeBien et al. BLOOD
- Regulation of T Cell Receptor Activation by Dynamic Membrane Binding of the CD3ɛ Cytoplasmic Tyrosine-Based Motif
- (2008) Chenqi Xu et al. CELL
- Clinical heterogeneity can hamper the diagnosis of patients with ZAP70 deficiency
- (2008) Tuba Turul et al. EUROPEAN JOURNAL OF PEDIATRICS
- The Balance between T Cell Receptor Signaling and Degradation at the Center of the Immunological Synapse Is Determined by Antigen Quality
- (2008) Sašo Čemerski et al. IMMUNITY
- T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity
- (2008) Jennifer D. Stone et al. IMMUNOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started