T Cell Activation

A Role for CD8 in the Developmental Tuning of Antigen Recognition and CD3 Conformational Change

(2014) D. Gil et al.   JOURNAL OF IMMUNOLOGY

The Proline-Rich Sequence of CD3  as an Amplifier of Low-Avidity TCR Signaling

(2014) P. Tailor et al.   JOURNAL OF IMMUNOLOGY

Glucose Uptake Is Limiting in T Cell Activation and Requires CD28-Mediated Akt-Dependent and Independent Pathways

(2014) S. R. Jacobs et al.   JOURNAL OF IMMUNOLOGY

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology

The Actin Cytoskeleton in T Cell Activation

(2008) Janis K. Burkhardt et al.   Annual Review of Immunology

Regulation of T Cell Receptor Activation by Dynamic Membrane Binding of the CD3ɛ Cytoplasmic Tyrosine-Based Motif

(2008) Chenqi Xu et al.   CELL

Calcium signaling in lymphocytes

(2008) Masatsugu Oh-hora et al.   CURRENT OPINION IN IMMUNOLOGY

Immune regulation and control of regulatory T cells by OX40 and 4-1BB

(2008) Takanori So et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Complementation In Trans of Altered Thymocyte Development in Mice Expressing Mutant Forms of the Adaptor Molecule SLP76

(2008) Martha S. Jordan et al.   IMMUNITY

T Cell Costimulation via the Integrin VLA-4 Inhibits the Actin-Dependent Centralization of Signaling Microclusters Containing the Adaptor SLP-76

(2008) Ken Nguyen et al.   IMMUNITY

Spatiotemporal Regulation of T Cell Costimulation by TCR-CD28 Microclusters and Protein Kinase C θ Translocation

(2008) Tadashi Yokosuka et al.   IMMUNITY

The Balance between T Cell Receptor Signaling and Degradation at the Center of the Immunological Synapse Is Determined by Antigen Quality

(2008) Sašo Čemerski et al.   IMMUNITY

T-cell activation through immunological synapses and kinapses

(2008) Michael L. Dustin   IMMUNOLOGICAL REVIEWS

TULA proteins regulate activity of the protein tyrosine kinase Syk

(2008) Rachana Agrawal et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Structural and Functional Evidence that Nck Interaction with CD3ε Regulates T-Cell Receptor Activity

(2008) Koh Takeuchi et al.   JOURNAL OF MOLECULAR BIOLOGY

T-Cell Receptor-Induced NF- B Activation Is Negatively Regulated by E3 Ubiquitin Ligase Cbl-b

(2008) G. Qiao et al.   MOLECULAR AND CELLULAR BIOLOGY

The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers

(2008) Aubin Penna et al.   NATURE

Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activation

(2008) Riina M. Luik et al.   NATURE

The proline-rich sequence of CD3ε controls T cell antigen receptor expression on and signaling potency in preselection CD4+CD8+ thymocytes

(2008) Michaël Mingueneau et al.   NATURE IMMUNOLOGY

Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance

(2008) Masatsugu Oh-hora et al.   NATURE IMMUNOLOGY

T cell antigen receptor stimulation induces MALT1 paracaspase–mediated cleavage of the NF-κB inhibitor A20

(2008) Beatrice Coornaert et al.   NATURE IMMUNOLOGY

The proteolytic activity of the paracaspase MALT1 is key in T cell activation

(2008) Fabien Rebeaud et al.   NATURE IMMUNOLOGY

NFAT Binding and Regulation of T Cell Activation by the Cytoplasmic Scaffolding Homer Proteins

(2008) G. N. Huang et al.   SCIENCE

TCR Triggering by the pMHC Complex: Valency, Affinity, and Dynamics

(2008) R. Varma   Science Signaling

A permissive geometry model for TCR–CD3 activation

(2008) Susana Minguet et al.   TRENDS IN BIOCHEMICAL SCIENCES

The receptor deformation model of TCR triggering

(2007) Zhengyu Ma et al.   FASEB JOURNAL