标题
Modulation of cellular processes by histone and non-histone protein acetylation
作者
关键词
-
出版物
NATURE REVIEWS MOLECULAR CELL BIOLOGY
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2022-01-18
DOI
10.1038/s41580-021-00441-y
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- Lysine Glutarylation Is a Protein Posttranslational Modification Regulated by SIRT5
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- SIRT2 induces the checkpoint kinase BubR1 to increase lifespan
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- The SAGA coactivator complex acts on the whole transcribed genome and is required for RNA polymerase II transcription
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- Ketogenesis prevents diet-induced fatty liver injury and hyperglycemia
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- Histone Methylation Has Dynamics Distinct from Those of Histone Acetylation in Cell Cycle Reentry from Quiescence
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- NEDD9 Regulates Actin Dynamics through Cortactin Deacetylation in an AURKA/HDAC6–Dependent Manner
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- Regulation of Autophagy by Cytosolic Acetyl-Coenzyme A
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- Regulation of RNA polymerase II activation by histone acetylation in single living cells
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- BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones
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- Histone deacetylase (HDAC) 1 and 2 are essential for accurate cell division and the pluripotency of embryonic stem cells
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- A Cascade of Histone Modifications Induces Chromatin Condensation in Mitosis
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- Sirt1 Extends Life Span and Delays Aging in Mice through the Regulation of Nk2 Homeobox 1 in the DMH and LH
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- Intracellular distribution of human SIRT7 and mapping of the nuclear/nucleolar localization signal
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- Histone Acetyltransferase 1 Promotes Homologous Recombination in DNA Repair by Facilitating Histone Turnover
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- Widespread and Enzyme-independentNϵ-Acetylation andNϵ-Succinylation of Proteins in the Chemical Conditions of the Mitochondrial Matrix
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- Regulation of a Dynamic Interaction between Two Microtubule-binding Proteins, EB1 and TIP150, by the Mitotic p300/CBP-associated Factor (PCAF) Orchestrates Kinetochore Microtubule Plasticity and Chromosome Stability during Mitosis
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- The role of the nucleosome acidic patch in modulating higher order chromatin structure
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- Acetylation of RNA Polymerase II Regulates Growth-Factor-Induced Gene Transcription in Mammalian Cells
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- SIRT4 Coordinates the Balance between Lipid Synthesis and Catabolism by Repressing Malonyl CoA Decarboxylase
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- Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli
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- SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways
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- SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine
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- MOZ increases p53 acetylation and premature senescence through its complex formation with PML
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- Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways
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- Circadian Clock NAD+ Cycle Drives Mitochondrial Oxidative Metabolism in Mice
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- αTAT1 is the major α-tubulin acetyltransferase in mice
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- Lysine Succinylation Is a Frequently Occurring Modification in Prokaryotes and Eukaryotes and Extensively Overlaps with Acetylation
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- Histone Deacetylase 2 (HDAC2) Regulates Chromosome Segregation and Kinetochore Function via H4K16 Deacetylation during Oocyte Maturation in Mouse
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- Metabolic Regulation of Epigenetics
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- SIRT3 Functions in the Nucleus in the Control of Stress-Related Gene Expression
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- SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation
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- The coactivator role of histone deacetylase 3 in IL-1-signaling involves deacetylation of p65 NF-κB
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- EB1 acetylation by P300/CBP-associated factor (PCAF) ensures accurate kinetochore-microtubule interactions in mitosis
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- Combinatorial Patterning of Chromatin Regulators Uncovered by Genome-wide Location Analysis in Human Cells
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- Nicotinamide Mononucleotide, a Key NAD+ Intermediate, Treats the Pathophysiology of Diet- and Age-Induced Diabetes in Mice
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- Acetyl-CoA Induces Cell Growth and Proliferation by Promoting the Acetylation of Histones at Growth Genes
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- Gene bookmarking accelerates the kinetics of post-mitotic transcriptional re-activation
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- Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes
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- Sirt5 Is a NAD-Dependent Protein Lysine Demalonylase and Desuccinylase
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- Proteome-Wide Mapping of the Drosophila Acetylome Demonstrates a High Degree of Conservation of Lysine Acetylation
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- The acetylation of tau inhibits its function and promotes pathological tau aggregation
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- Hdac3 Is Essential for the Maintenance of Chromatin Structure and Genome Stability
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- The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α
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- Emphasizing the positive: A role for histone deacetylases in transcriptional activation
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- Interdependence of AMPK and SIRT1 for Metabolic Adaptation to Fasting and Exercise in Skeletal Muscle
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- The ATAC acetyl transferase complex controls mitotic progression by targeting non-histone substrates
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- Gcn5 regulates the dissociation of SWI/SNF from chromatin by acetylation of Swi2/Snf2
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- HDAC3 Is Negatively Regulated by the Nuclear Protein DBC1
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- Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy
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- Genome-wide Mapping of HATs and HDACs Reveals Distinct Functions in Active and Inactive Genes
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- SIRT5 Deacetylates Carbamoyl Phosphate Synthetase 1 and Regulates the Urea Cycle
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- BubR1 acetylation at prometaphase is required for modulating APC/C activity and timing of mitosis
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- Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes
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- Subunit Composition and Substrate Specificity of a MOF-containing Histone Acetyltransferase Distinct from the Male-specific Lethal (MSL) Complex
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- CBP and p300 are cytoplasmic E4 polyubiquitin ligases for p53
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- Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
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- ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation
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- Nicotinic Acid, Nicotinamide, and Nicotinamide Riboside: A Molecular Evaluation of NAD+ Precursor Vitamins in Human Nutrition
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- Probing Nucleosome Function: A Highly Versatile Library of Synthetic Histone H3 and H4 Mutants
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- The NAD+-Dependent Deacetylase SIRT1 Modulates CLOCK-Mediated Chromatin Remodeling and Circadian Control
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- SIRT1 Regulates Circadian Clock Gene Expression through PER2 Deacetylation
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- Glucose Restriction Inhibits Skeletal Myoblast Differentiation by Activating SIRT1 through AMPK-Mediated Regulation of Nampt
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- Tissue-specific regulation of SIRT1 by calorie restriction
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- Molecular Architecture of Quartet MOZ/MORF Histone Acetyltransferase Complexes
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- The Double-Histone-Acetyltransferase Complex ATAC Is Essential for Mammalian Development
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- The structural basis of protein acetylation by the p300/CBP transcriptional coactivator
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- Combinatorial patterns of histone acetylations and methylations in the human genome
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- A comprehensive library of histone mutants identifies nucleosomal residues required for H3K4 methylation
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