KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification

CDK1 Prevents Unscheduled PLK4-STIL Complex Assembly in Centriole Biogenesis

(2016) Sihem Zitouni et al.   CURRENT BIOLOGY

Subunits of ADA-two-A-containing (ATAC) or Spt-Ada-Gcn5-acetyltrasferase (SAGA) Coactivator Complexes Enhance the Acetyltransferase Activity of GCN5

(2015) Anne Riss et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Binding of STIL to Plk4 activates kinase activity to promote centriole assembly

(2015) Tyler C. Moyer et al.   JOURNAL OF CELL BIOLOGY

2016 update of the PRIDE database and its related tools

(2015) Juan Antonio Vizcaíno et al.   NUCLEIC ACIDS RESEARCH

Autoinhibition and relief mechanism for Polo-like kinase 4

(2015) Joseph E. Klebba et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reversible centriole depletion with an inhibitor of Polo-like kinase 4

(2015) Y. L. Wong et al.   SCIENCE

Acetylation of cyclin-dependent kinase 5 is mediated by GCN5

(2014) Juhyung Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Drugging MYCN through an Allosteric Transition in Aurora Kinase A

(2014) William Clay Gustafson et al.   CANCER CELL

Lysine acetylation: enzymes, bromodomains and links to different diseases: Figure 1.

(2014) Linya You et al.   Essays in Biochemistry

The centrosome duplication cycle in health and disease

(2014) Erich A. Nigg et al.   FEBS LETTERS

Mechanisms of HsSAS-6 assembly promoting centriole formation in human cells

(2014) Debora Keller et al.   JOURNAL OF CELL BIOLOGY

The Discovery of Polo-Like Kinase 4 Inhibitors: Design and Optimization of Spiro[cyclopropane-1,3′[3H]indol]-2′(1′H)-ones as Orally Bioavailable Antitumor Agents

(2014) Peter B. Sampson et al.   JOURNAL OF MEDICINAL CHEMISTRY

Causes and consequences of centrosome abnormalities in cancer

(2014) S. A. Godinho et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

CHARMM36 all-atom additive protein force field: Validation based on comparison to NMR data

(2013) Jing Huang et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Differential Role of the Protein Matrix on the Binding of a Catalytic Aspartate to Mg2+ vs Ca2+: Application to Ribonuclease H

(2013) C. Satheesan Babu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Manteia, a predictive data mining system for vertebrate genes and its applications to human genetic diseases

(2013) Olivier Tassy et al.   NUCLEIC ACIDS RESEARCH

Suppression of centrosome duplication and amplification by deacetylases

(2012) Hongbo Ling et al.   CELL CYCLE

Lysine Acetylation Is Widespread on Proteins of Diverse Function and Localization in the Protozoan Parasite Toxoplasma gondii

(2012) Victoria Jeffers et al.   EUKARYOTIC CELL

ATAC-king the complexity of SAGA during evolution

(2012) G. Spedale et al.   GENES & DEVELOPMENT

Proteome-wide Analysis of Lysine Acetylation Suggests its Broad Regulatory Scope inSaccharomyces cerevisiae

(2012) Peter Henriksen et al.   MOLECULAR & CELLULAR PROTEOMICS

Position-Specific Analysis and Prediction for Protein Lysine Acetylation Based on Multiple Features

(2012) Sheng-Bao Suo et al.   PLoS One

Proteomic Analysis of Lysine Acetylation Sites in Rat Tissues Reveals Organ Specificity and Subcellular Patterns

(2012) Alicia Lundby et al.   Cell Reports

3D-structured illumination microscopy provides novel insight into architecture of human centrosomes

(2012) Katharina F. Sonnen et al.   Biology Open

A possible overestimation of the effect of acetylation on lysine residues in KQ mutant analysis

(2011) Hirofumi Fujimoto et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Catalytic Control in the EGF Receptor and Its Connection to General Kinase Regulatory Mechanisms

(2011) Natalia Jura et al.   MOLECULAR CELL

PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse

(2011) P. V. Hornbeck et al.   NUCLEIC ACIDS RESEARCH

Search for Diphoton Events with Large Missing Transverse Energy in 7 TeV Proton-Proton Collisions with the ATLAS Detector

(2011) G. Aad et al.   PHYSICAL REVIEW LETTERS

Proteome-Wide Mapping of the Drosophila Acetylome Demonstrates a High Degree of Conservation of Lysine Acetylation

(2011) B. T. Weinert et al.   Science Signaling

Histone Deacetylase 8 Is Required for Centrosome Cohesion and Influenza A Virus Entry

(2011) Yohei Yamauchi et al.   PLoS Pathogens

Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation

(2010) Qihuang Jin et al.   EMBO JOURNAL

The ATAC acetyl transferase complex controls mitotic progression by targeting non-histone substrates

(2010) Meritxell Orpinell et al.   EMBO JOURNAL

The Tale of Protein Lysine Acetylation in the Cytoplasm

(2010) Karin Sadoul et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Polo-like kinase 4 kinase activity limits centrosome overduplication by autoregulating its own stability

(2010) Andrew J. Holland et al.   JOURNAL OF CELL BIOLOGY

Cep152 interacts with Plk4 and is required for centriole duplication

(2010) Emily M. Hatch et al.   JOURNAL OF CELL BIOLOGY

GCN5 Is a Positive Regulator of Origins of DNA Replication in Saccharomyces cerevisiae

(2010) Maria Claudia Espinosa et al.   PLoS One

Plk4 is required for cytokinesis and maintenance of chromosomal stability

(2010) C. O. Rosario et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polo-like kinase 4: the odd one out of the family

(2010) James E Sillibourne et al.   Cell Division

GCN5-mediated Transcriptional Control of the Metabolic Coactivator PGC-1β through Lysine Acetylation

(2009) Timothy J. Kelly et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CHARMM: The biomolecular simulation program

(2009) B. R. Brooks et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Autophosphorylation of Polo-like Kinase 4 and Its Role in Centriole Duplication

(2009) James E. Sillibourne et al.   MOLECULAR BIOLOGY OF THE CELL

Acetylation by GCN5 regulates CDC6 phosphorylation in the S phase of the cell cycle

(2009) Roberta Paolinelli et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The transcriptional co-activator PCAF regulates cdk2 activity

(2009) Francesca Mateo et al.   NUCLEIC ACIDS RESEARCH

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

Human ATAC Is a GCN5/PCAF-containing Acetylase Complex with a Novel NC2-like Histone Fold Module That Interacts with the TATA-binding Protein

(2008) Yuan-Liang Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysine Acetylation Is a Highly Abundant and Evolutionarily Conserved Modification inEscherichia Coli

(2008) Junmei Zhang et al.   MOLECULAR & CELLULAR PROTEOMICS

Acetylation of Conserved Lysines in the Catalytic Core of Cyclin-Dependent Kinase 9 Inhibits Kinase Activity and Regulates Transcription

(2008) A. Sabo et al.   MOLECULAR AND CELLULAR BIOLOGY

Lysine Acetylation: Codified Crosstalk with Other Posttranslational Modifications

(2008) Xiang-Jiao Yang et al.   MOLECULAR CELL