标题
A common signature of cellular senescence; does it exist?
作者
关键词
Aging, Atypical cell divisions, Autophagy, Cell cycle, Cellular senescence, Chromatin reorganization, Nuclear structure, polyploidisation, Senescence-associated secretory phenotype
出版物
AGEING RESEARCH REVIEWS
Volume 71, Issue -, Pages 101458
出版商
Elsevier BV
发表日期
2021-09-07
DOI
10.1016/j.arr.2021.101458
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Mitotic checkpoint defects: en route to cancer and drug resistance
- (2021) Sinjini Sarkar et al. CHROMOSOME RESEARCH
- CELL CYCLE STRESS IN NORMAL HUMAN CELLS: A ROUTE TO “FIRST CELLS” (WITH/WITHOUT FITNESS GAIN) AND CANCER-LIKE CELL-SHAPE CHANGES
- (2021) Kirsten H Walen SEMINARS IN CANCER BIOLOGY
- Cellular aging beyond cellular senescence: Markers of senescence prior to cell cycle arrest in vitro and in vivo
- (2021) Mikolaj Ogrodnik AGING CELL
- Cell cycle re-entry and arrest in G2/M phase induces senescence and fibrosis in Fuchs Endothelial Corneal Dystrophy
- (2021) Tomas L. White et al. FREE RADICAL BIOLOGY AND MEDICINE
- Nuclear localization of p65 reverses therapy induced senescence
- (2021) Sameer Salunkhe et al. JOURNAL OF CELL SCIENCE
- Deterioration of nuclear morphology and architecture: A hallmark of senescence and aging
- (2021) Rashmi Upadhyay Pathak et al. AGEING RESEARCH REVIEWS
- Algorithmic assessment of cellular senescence in experimental and clinical specimens
- (2021) J. Kohli et al. Nature Protocols
- Chromatin-Directed Proteomics Identifies ZNF84 as a p53-Independent Regulator of p21 in Genotoxic Stress Response
- (2021) Anna Strzeszewska-Potyrała et al. Cancers
- Dissecting primary and secondary senescence to enable new senotherapeutic strategies
- (2021) Tesfahun Dessale Admasu et al. AGEING RESEARCH REVIEWS
- Intratumor Heterogeneity and Therapy Resistance: Contributions of Dormancy, Apoptosis Reversal (Anastasis) and Cell Fusion to Disease Recurrence
- (2020) Razmik Mirzayans et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- A proteomic atlas of senescence-associated secretomes for aging biomarker development
- (2020) Nathan Basisty et al. PLOS BIOLOGY
- Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells
- (2020) Emanuela Mensà et al. Journal of Extracellular Vesicles
- Nuclear envelope dysfunction and its contribution to the aging process
- (2020) Filipa Martins et al. AGING CELL
- Senescence in Post-Mitotic Cells: A Driver of Aging?
- (2020) Thomas von Zglinicki et al. ANTIOXIDANTS & REDOX SIGNALING
- Functional heterogeneity in senescence
- (2020) Kristina Kirschner et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- “Mitotic Slippage” and Extranuclear DNA in Cancer Chemoresistance: A Focus on Telomeres
- (2020) Kristine Salmina et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Oncogene-induced senescence: From biology to therapy
- (2020) Haoran Zhu et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Long-lived post-mitotic cell aging: is a telomere clock at play?
- (2020) Maria Sol Jacome-Burbano et al. MECHANISMS OF AGEING AND DEVELOPMENT
- The Bright and Dark Side of Extracellular Vesicles in the Senescence-Associated Secretory Phenotype
- (2020) Ryan Wallis et al. MECHANISMS OF AGEING AND DEVELOPMENT
- 4D Genome Rewiring during Oncogene-Induced and Replicative Senescence
- (2020) Satish Sati et al. MOLECULAR CELL
- Senescent Cells: Emerging Targets for Human Aging and Age-Related Diseases
- (2020) Shuling Song et al. TRENDS IN BIOCHEMICAL SCIENCES
- Therapy-Induced Senescence: An “Old” Friend Becomes the Enemy
- (2020) Tareq Saleh et al. Cancers
- Senolytic drugs: from discovery to translation
- (2020) J. L. Kirkland et al. JOURNAL OF INTERNAL MEDICINE
- Induction and transmission of oncogene-induced senescence
- (2020) Nattaphong Rattanavirotkul et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- A guide to assessing cellular senescence in vitro and in vivo
- (2020) Estela González‐Gualda et al. FEBS Journal
- Improved Autophagic Flux in Escapers from Doxorubicin-Induced Senescence/Polyploidy of Breast Cancer Cells
- (2020) Agnieszka Bojko et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- IQGAP1-dysfunction leads to induction of senescence in human vascular smooth muscle cells
- (2020) Wioleta Grabowska et al. MECHANISMS OF AGEING AND DEVELOPMENT
- ATM-deficient neural precursors develop senescence phenotype with disturbances in autophagy
- (2020) Piotr Sunderland et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Senescence-activated enhancer landscape orchestrates the senescence-associated secretory phenotype in murine fibroblasts
- (2020) Yiting Guan et al. NUCLEIC ACIDS RESEARCH
- Cell dormancy plasticity: quiescence deepens into senescence through a dimmer switch
- (2020) Kotaro Fujimaki et al. PHYSIOLOGICAL GENOMICS
- Epilipidomics of Senescent Dermal Fibroblasts Identify Lysophosphatidylcholines as Pleiotropic Senescence-Associated Secretory Phenotype (SASP) Factors
- (2020) Marie-Sophie Narzt et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Cellular senescence in ageing: from mechanisms to therapeutic opportunities
- (2020) Raffaella Di Micco et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Therapy-induced polyploidization and senescence: Coincidence or interconnection?
- (2020) Ewa Sikora et al. SEMINARS IN CANCER BIOLOGY
- Targeting tumor cell senescence and polyploidy as potential therapeutic strategies
- (2020) Tareq Saleh et al. SEMINARS IN CANCER BIOLOGY
- Inhibition of NADPH Oxidases Activity by Diphenyleneiodonium Chloride as a Mechanism of Senescence Induction in Human Cancer Cells
- (2020) Katarzyna Piszczatowska et al. Antioxidants
- Regulation of senescence escape by TSP1 and CD47 following chemotherapy treatment
- (2019) Jordan Guillon et al. Cell Death & Disease
- L1 drives IFN in senescent cells and promotes age-associated inflammation
- (2019) Marco De Cecco et al. NATURE
- Nuclear pore density controls heterochromatin reorganization during senescence
- (2019) Charlene Boumendil et al. GENES & DEVELOPMENT
- Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence
- (2019) Rhys Anderson et al. EMBO JOURNAL
- Excessive Cell Growth Causes Cytoplasm Dilution And Contributes to Senescence
- (2019) Gabriel E. Neurohr et al. CELL
- Tumor Cell Escape from Therapy-Induced Senescence as a Model of Disease Recurrence after Dormancy
- (2019) Tareq Saleh et al. CANCER RESEARCH
- Stress-activated miR-204 governs senescent phenotypes of chondrocytes to promote osteoarthritis development
- (2019) Donghyun Kang et al. Science Translational Medicine
- A functional genetic screen defines the AKT-induced senescence signaling network
- (2019) Keefe T. Chan et al. CELL DEATH AND DIFFERENTIATION
- Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3
- (2019) Michela Borghesan et al. Cell Reports
- The “life code”: a theory that unifies the human life cycle and the origin of human tumors
- (2019) Liu Jinsong SEMINARS IN CANCER BIOLOGY
- SILAC Analysis Reveals Increased Secretion of Hemostasis-Related Factors by Senescent Cells
- (2019) Christopher D. Wiley et al. Cell Reports
- Targeting normal and cancer senescent cells as a strategy of senotherapy
- (2019) Ewa Sikora et al. AGEING RESEARCH REVIEWS
- Proteostasis failure and cellular senescence in long‐term cultured postmitotic rat neurons
- (2019) Shoma Ishikawa et al. AGING CELL
- Cellular Senescence: Defining a Path Forward
- (2019) Vassilis Gorgoulis et al. CELL
- Senescence in polyploid giant cancer cells: A road that leads to chemoresistance
- (2019) Deblina Bharadwaj et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Diversity of the Senescence Phenotype of Cancer Cells Treated with Chemotherapeutic Agents
- (2019) Agnieszka Bojko et al. Cells
- Chronic inflammation in the etiology of disease across the life span
- (2019) David Furman et al. NATURE MEDICINE
- Small extracellular vesicles and their miRNA cargo are anti-apoptotic members of the senescence-associated secretory phenotype
- (2018) Lucia Terlecki-Zaniewicz et al. Aging-US
- Polyploidy in tissue homeostasis and regeneration
- (2018) Jan Inge Øvrebø et al. DEVELOPMENT
- Mechanisms and functions of cellular senescence
- (2018) Nicolás Herranz et al. JOURNAL OF CLINICAL INVESTIGATION
- PTENdeletion in luminal cells of mature prostate induces replication stress and senescence in vivo
- (2018) Maxime Parisotto et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The senescent bystander effect is caused by ROS-activated NF-κB signalling
- (2018) Glyn Nelson et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Stress, cell senescence and organismal ageing
- (2018) João Pedro de Magalhães et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Is DNA damage indispensable for stress-induced senescence?
- (2018) Anna Bielak-Zmijewska et al. MECHANISMS OF AGEING AND DEVELOPMENT
- HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and Induces CTCF Clustering across Cell Types
- (2018) Anne Zirkel et al. MOLECULAR CELL
- Cellular Senescence in Postmitotic Cells: Beyond Growth Arrest
- (2018) Przemyslaw Sapieha et al. TRENDS IN CELL BIOLOGY
- Senescence-associated secretory factors induced by cisplatin in melanoma cells promote non-senescent melanoma cell growth through activation of the ERK1/2-RSK1 pathway
- (2018) Xuerong Sun et al. Cell Death & Disease
- Insight into the role of PIKK family members and NF-кB in DNAdamage-induced senescence and senescence-associated secretory phenotype of colon cancer cells
- (2018) Anna Strzeszewska et al. Cell Death & Disease
- Correction to: Comparison of multiple transcriptomes exposes unified and divergent features of quiescent and activated skeletal muscle stem cells
- (2018) Natalia Pietrosemoli et al. Skeletal Muscle
- Roles of Polyploid/Multinucleated Giant Cancer Cells in Metastasis and Disease Relapse Following Anticancer Treatment
- (2018) et al. Cancers
- Aging, Cell Senescence, and Chronic Disease
- (2018) Tamara Tchkonia et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- The Senescence–Stemness Alliance – A Cancer-Hijacked Regeneration Principle
- (2018) Maja Milanovic et al. TRENDS IN CELL BIOLOGY
- Persistent repair intermediates induce senescence
- (2018) F. M. Feringa et al. Nature Communications
- A nuclear lamina-chromatin-Ran GTPase axis modulates nuclear import and DNA damage signaling
- (2018) Natalia Dworak et al. AGING CELL
- Tumor cell escape from therapy-induced senescence
- (2018) Tareq Saleh et al. BIOCHEMICAL PHARMACOLOGY
- The dynamic nature of senescence in cancer
- (2018) Soyoung Lee et al. NATURE CELL BIOLOGY
- Coaching from the sidelines: the nuclear periphery in genome regulation
- (2018) Abigail Buchwalter et al. NATURE REVIEWS GENETICS
- NK cell–mediated cytotoxicity contributes to tumor control by a cytostatic drug combination
- (2018) Marcus Ruscetti et al. SCIENCE
- The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration
- (2017) Birgit Ritschka et al. GENES & DEVELOPMENT
- Massive reshaping of genome–nuclear lamina interactions during oncogene-induced senescence
- (2017) Christelle Lenain et al. GENOME RESEARCH
- Senescence-associated reprogramming promotes cancer stemness
- (2017) Maja Milanovic et al. NATURE
- Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence
- (2017) Selene Glück et al. NATURE CELL BIOLOGY
- cGAS is essential for cellular senescence
- (2017) Hui Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Small extracellular vesicles secreted from senescent cells promote cancer cell proliferation through EphA2
- (2017) Masaki Takasugi et al. Nature Communications
- Protein and chemotherapy profiling of extracellular vesicles harvested from therapeutic induced senescent triple negative breast cancer cells
- (2017) E L Kavanagh et al. Oncogenesis
- Impact of lysosome status on extracellular vesicle content and release
- (2016) Erez Eitan et al. AGEING RESEARCH REVIEWS
- Prelamin A impairs 53BP1 nuclear entry by mislocalizing NUP153 and disrupting the Ran gradient
- (2016) Andrew M. Cobb et al. AGING CELL
- Unbiased analysis of senescence associated secretory phenotype (SASP) to identify common components following different genotoxic stresses
- (2016) Servet Özcan et al. Aging-US
- How autophagy both activates and inhibits cellular senescence
- (2016) Chanhee Kang et al. Autophagy
- Aberrant localization of lamin B receptor (LBR) in cellular senescence in human cells
- (2016) Rumi Arai et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Loss of lamin B receptor is necessary to induce cellular senescence
- (2016) Emilie Lukášová et al. BIOCHEMICAL JOURNAL
- Distinct Functions of Senescence-Associated Immune Responses in Liver Tumor Surveillance and Tumor Progression
- (2016) Tobias Eggert et al. CANCER CELL
- Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype
- (2016) Christopher D. Wiley et al. Cell Metabolism
- Morphological and Functional Characteristic of Senescent Cancer Cells
- (2016) Ewa Sikora et al. CURRENT DRUG TARGETS
- Is Senescence Reversible?
- (2016) Shweta Chakradeo et al. CURRENT DRUG TARGETS
- Autophagy deficient melanocytes display a senescence associated secretory phenotype that includes oxidized lipid mediators
- (2016) Chunya Ni et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- HMGB2 orchestrates the chromatin landscape of senescence-associated secretory phenotype gene loci
- (2016) Katherine M. Aird et al. JOURNAL OF CELL BIOLOGY
- Old cells, new tricks: chromatin structure in senescence
- (2016) Aled John Parry et al. MAMMALIAN GENOME
- Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
- (2016) Darren J. Baker et al. NATURE
- NOTCH1 mediates a switch between two distinct secretomes during senescence
- (2016) Matthew Hoare et al. NATURE CELL BIOLOGY
- Spatial organization of chromatin domains and compartments in single chromosomes
- (2016) Siyuan Wang et al. SCIENCE
- The Chromatin Landscape of Cellular Senescence
- (2016) Steven W. Criscione et al. TRENDS IN GENETICS
- BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance
- (2016) N. Tasdemir et al. Cancer Discovery
- NOX4 downregulation leads to senescence of human vascular smooth muscle cells
- (2016) Dorota Przybylska et al. Oncotarget
- Bafilomycin A1 triggers proliferative potential of senescent cancer cells in vitro and in NOD/SCID mice
- (2016) Halina Was et al. Oncotarget
- Is senescence-associated β-galactosidase a marker of neuronal senescence?
- (2016) Malgorzata Piechota et al. Oncotarget
- IL1- and TGFβ-Nox4 signaling, oxidative stress and DNA damage response are shared features of replicative, oncogene-induced, and drug-induced paracrine ‘Bystander senescence’
- (2016) Sona Hubackova et al. Aging-US
- Cell cycle arrest is not yet senescence, which is not just cell cycle arrest: terminology for TOR-driven aging
- (2016) Mikhail V. Blagosklonny Aging-US
- Replicatively senescent cells are arrested in G1 and G2 phases
- (2016) Zhiyong Mao et al. Aging-US
- Specific lipofuscin staining as a novel biomarker to detect replicative and stress-induced senescence. A method applicable in cryo-preserved and archival tissues
- (2016) EA Georgakopoulou et al. Aging-US
- Autophagy-mediated degradation of nuclear envelope proteins during oncogene-induced senescence
- (2015) Christelle Lenain et al. CARCINOGENESIS
- The senescent microenvironment promotes the emergence of heterogeneous cancer stem-like cells
- (2015) Luis Jaime Castro-Vega et al. CARCINOGENESIS
- Role of stress-activated OCT4A in the cell fate decisions of embryonal carcinoma cells treated with etoposide
- (2015) Anda Huna et al. CELL CYCLE
- Senescence from G2 arrest, revisited
- (2015) Véronique Gire et al. CELL CYCLE
- MacroH2A1 and ATM Play Opposing Roles in Paracrine Senescence and the Senescence-Associated Secretory Phenotype
- (2015) Hongshan Chen et al. MOLECULAR CELL
- Autophagy mediates degradation of nuclear lamina
- (2015) Zhixun Dou et al. NATURE
- MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation
- (2015) Remi-Martin Laberge et al. NATURE CELL BIOLOGY
- The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4
- (2015) C. Kang et al. SCIENCE
- In vitro evidence for senescent multinucleated melanocytes as a source for tumor-initiating cells
- (2015) C Leikam et al. Cell Death & Disease
- Global Reorganization of the Nuclear Landscape in Senescent Cells
- (2015) Tamir Chandra et al. Cell Reports
- Contribution of Topological Domains and Loop Formation to 3D Chromatin Organization
- (2015) Vuthy Ea et al. Genes
- Polyploidy Formation in Doxorubicin-Treated Cancer Cells Can Favor Escape from Senescence
- (2015) Grazyna Mosieniak et al. NEOPLASIA
- Sustained activation of DNA damage response in irradiated apoptosis-resistant cells induces reversible senescence associated with mTOR downregulation and expression of stem cell markers
- (2014) Zhanna V Chitikova et al. CELL CYCLE
- Gene expression profiling of replicative and induced senescence
- (2014) Maggie Purcell et al. CELL CYCLE
- Transient Activation of p53 in G2 Phase Is Sufficient to Induce Senescence
- (2014) Lenno Krenning et al. MOLECULAR CELL
- Necessary and Sufficient Role for a Mitosis Skip in Senescence Induction
- (2014) Yoshikazu Johmura et al. MOLECULAR CELL
- Ki67 is a promising molecular target in the diagnosis of cancer (Review)
- (2014) LIAN TAO LI et al. Molecular Medicine Reports
- The role of senescent cells in ageing
- (2014) Jan M. van Deursen NATURE
- Stable Cellular Senescence Is Associated with Persistent DDR Activation
- (2014) Marzia Fumagalli et al. PLoS One
- Enhancing Chemotherapy Efficacy in Pten -Deficient Prostate Tumors by Activating the Senescence-Associated Antitumor Immunity
- (2014) Alberto Toso et al. Cell Reports
- Cytoprotective and nonprotective autophagy in cancer therapy
- (2013) David A. Gewirtz Autophagy
- A comparison of replicative senescence and doxorubicin-induced premature senescence of vascular smooth muscle cells isolated from human aorta
- (2013) Anna Bielak-Zmijewska et al. BIOGERONTOLOGY
- Programmed Cell Senescence during Mammalian Embryonic Development
- (2013) Daniel Muñoz-Espín et al. CELL
- Senescence Is a Developmental Mechanism that Contributes to Embryonic Growth and Patterning
- (2013) Mekayla Storer et al. CELL
- The Proliferation-Quiescence Decision Is Controlled by a Bifurcation in CDK2 Activity at Mitotic Exit
- (2013) Sabrina L. Spencer et al. CELL
- DNA damage causes TP53-dependent coupling of self-renewal and senescence pathways in embryonal carcinoma cells
- (2013) Thomas R. Jackson et al. CELL CYCLE
- MEK drives cyclin D1 hyperelevation during geroconversion
- (2013) O V Leontieva et al. CELL DEATH AND DIFFERENTIATION
- Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape
- (2013) P. P. Shah et al. GENES & DEVELOPMENT
- Ionizing Radiation-Induced Responses in Human Cells with Differing TP53 Status
- (2013) Razmik Mirzayans et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Lysosome-mediated processing of chromatin in senescence
- (2013) Andre Ivanov et al. JOURNAL OF CELL BIOLOGY
- p53-dependent chemokine production by senescent tumor cells supports NKG2D-dependent tumor elimination by natural killer cells
- (2013) Alexandre Iannello et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A complex secretory program orchestrated by the inflammasome controls paracrine senescence
- (2013) Juan Carlos Acosta et al. NATURE CELL BIOLOGY
- Quantitative assessment of higher-order chromatin structure of the INK4/ARF locus in human senescent cells
- (2012) Akiyuki Hirosue et al. AGING CELL
- A senescent cell bystander effect: senescence-induced senescence
- (2012) Glyn Nelson et al. AGING CELL
- Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response
- (2012) Diana Jurk et al. AGING CELL
- Nuclear Cloning and Direct Reprogramming: The Long and the Short Path to Stockholm
- (2012) Rudolf Jaenisch Cell Stem Cell
- Inhibition of ATM blocks the etoposide-induced DNA damage response and apoptosis of resting human T cells
- (2012) Z. Korwek et al. DNA REPAIR
- Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions
- (2012) Anitha Suram et al. EMBO JOURNAL
- Polyploidy road to therapy-induced cellular senescence and escape
- (2012) Qin Wang et al. INTERNATIONAL JOURNAL OF CANCER
- Curcumin induces permanent growth arrest of human colon cancer cells: Link between senescence and autophagy
- (2012) Grazyna Mosieniak et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Lamin B1 loss is a senescence-associated biomarker
- (2012) Adam Freund et al. MOLECULAR BIOLOGY OF THE CELL
- Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation
- (2012) Marzia Fumagalli et al. NATURE CELL BIOLOGY
- Senescence-associated secretory phenotype favors the emergence of cancer stem-like cells
- (2012) J Cahu et al. Cell Death & Disease
- Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence
- (2012) Graeme Hewitt et al. Nature Communications
- Conserved cysteine residues in the mammalian lamin A tail are essential for cellular responses to ROS generation
- (2011) Vanja Pekovic et al. AGING CELL
- Formation of solid tumors by a single multinucleated cancer cell
- (2011) Zhang Weihua et al. CANCER
- Cancer stem cells and escape from drug-induced premature senescence in human lung tumor cells: Implications for drug resistance and in vitro drug screening models
- (2011) Michal Sabisz et al. CELL CYCLE
- Pseudo-DNA damage response in senescent cells
- (2011) Tatyana V. Pospelova et al. CELL CYCLE
- p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype
- (2011) Adam Freund et al. EMBO JOURNAL
- Hypertrophy hypothesis as an alternative explanation of the phenomenon of replicative aging of yeast
- (2011) Tomasz Biliński et al. FEMS YEAST RESEARCH
- Control of the senescence-associated secretory phenotype by NF- B promotes senescence and enhances chemosensitivity
- (2011) Y. Chien et al. GENES & DEVELOPMENT
- Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblasts
- (2011) Kan Cao et al. JOURNAL OF CLINICAL INVESTIGATION
- Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer
- (2011) Raffaella Di Micco et al. NATURE CELL BIOLOGY
- AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy
- (2011) M V Astle et al. ONCOGENE
- Silencing Nuclear Pore Protein Tpr Elicits a Senescent-Like Phenotype in Cancer Cells
- (2011) Brigitte David-Watine PLoS One
- Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes
- (2011) M. Narita et al. SCIENCE
- Impact of cellular senescence signature on ageing research
- (2010) Ewa Sikora et al. AGEING RESEARCH REVIEWS
- A chemotherapy-associated senescence bystander effect in breast cancer cells
- (2010) Xu Di et al. CANCER BIOLOGY & THERAPY
- Aging: ROS or TOR
- (2010) Mikhail V Blagosklonny CELL CYCLE
- Polyploidy: The Link Between Senescence and Cancer
- (2010) G. Mosieniak et al. CURRENT PHARMACEUTICAL DESIGN
- Replication stress and oxidative damage contribute to aberrant constitutive activation of DNA damage signalling in human gliomas
- (2010) J Bartkova et al. ONCOGENE
- Inflammatory networks during cellular senescence: causes and consequences
- (2010) Adam Freund et al. TRENDS IN MOLECULAR MEDICINE
- Senescence-Associated Oxidative DNA Damage Promotes the Generation of Neoplastic Cells
- (2009) K. Gosselin et al. CANCER RESEARCH
- Age-Dependent Deterioration of Nuclear Pore Complexes Causes a Loss of Nuclear Integrity in Postmitotic Cells
- (2009) Maximiliano A. D'Angelo et al. CELL
- Senescence impairs successful reprogramming to pluripotent stem cells
- (2009) A. Banito et al. GENES & DEVELOPMENT
- The DNA-damage response in human biology and disease
- (2009) Stephen P. Jackson et al. NATURE
- Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion
- (2009) Francis Rodier et al. NATURE CELL BIOLOGY
- Cell surface-bound IL-1 is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network
- (2009) A. V. Orjalo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome
- (2009) E. Lieberman-Aiden et al. SCIENCE
- Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network
- (2008) Thomas Kuilman et al. CELL
- Chemokine Signaling via the CXCR2 Receptor Reinforces Senescence
- (2008) Juan C. Acosta et al. CELL
- Tumor cells can escape DNA-damaging cisplatin through DNA endoreduplication and reversible polyploidy
- (2008) Pierre-Emmanuel Puig et al. CELL BIOLOGY INTERNATIONAL
- The evolution of haploidy and diploidy
- (2008) Sarah P. Otto et al. CURRENT BIOLOGY
- Induction of senescence with doxorubicin leads to increased genomic instability of HCT116 cells
- (2008) Malgorzata A. Sliwinska et al. MECHANISMS OF AGEING AND DEVELOPMENT
- The metabolic syndrome, IGF-1, and insulin action
- (2008) Yasumichi Arai et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions
- (2008) Lars Guelen et al. NATURE
- Structure, dynamics and function of nuclear pore complexes
- (2008) Maximiliano A. D’Angelo et al. TRENDS IN CELL BIOLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started