Cell dormancy plasticity: quiescence deepens into senescence through a dimmer switch

Spontaneously slow-cycling subpopulations of human cells originate from activation of stress-response pathways

(2019) Mingwei Min et al.   PLOS BIOLOGY

Cellular Senescence: Defining a Path Forward

(2019) Vassilis Gorgoulis et al.   CELL

Graded regulation of cellular quiescence depth between proliferation and senescence by a lysosomal dimmer switch

(2019) Kotaro Fujimaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elimination of quiescent slow-cycling cells via reducing quiescence depth by natural compounds purified from Ganoderma lucidum

(2017) Jian Dai et al.   Oncotarget

Autophagy maintains stemness by preventing senescence

(2016) Laura García-Prat et al.   NATURE

CDK6 Levels Regulate Quiescence Exit in Human Hematopoietic Stem Cells

(2015) Elisa Laurenti et al.   Cell Stem Cell

Single-Cell Transcriptomics Reveals a Population of Dormant Neural Stem Cells that Become Activated upon Brain Injury

(2015) Enric Llorens-Bobadilla et al.   Cell Stem Cell

Cellular senescence in aging and age-related disease: from mechanisms to therapy

(2015) Bennett G Childs et al.   NATURE MEDICINE

mTORC1 controls the adaptive transition of quiescent stem cells from G0 to GAlert

(2014) Joseph T. Rodgers et al.   NATURE

Long-Term Quiescent Fibroblast Cells Transit into Senescence

(2014) Shiva Marthandan et al.   PLoS One

Modelling mammalian cellular quiescence

(2014) G. Yao   Interface Focus

The Proliferation-Quiescence Decision Is Controlled by a Bifurcation in CDK2 Activity at Mitotic Exit

(2013) Sabrina L. Spencer et al.   CELL

Quiescent fibroblasts are protected from proteasome inhibition–mediated toxicity

(2012) Aster Legesse-Miller et al.   MOLECULAR BIOLOGY OF THE CELL

Four faces of cellular senescence

(2011) Francis Rodier et al.   JOURNAL OF CELL BIOLOGY

Origin of bistability underlying mammalian cell cycle entry

(2011) G. Yao et al.   Molecular Systems Biology

Autophagy Impairment Induces Premature Senescence in Primary Human Fibroblasts

(2011) Hyun Tae Kang et al.   PLoS One

Control of the Reversibility of Cellular Quiescence by the Transcriptional Repressor HES1

(2008) L. Sang et al.   SCIENCE