标题
The β Cell in Diabetes: Integrating Biomarkers With Functional Measures
作者
关键词
-
出版物
ENDOCRINE REVIEWS
Volume -, Issue -, Pages -
出版商
The Endocrine Society
发表日期
2021-06-28
DOI
10.1210/endrev/bnab021
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The First Genome-Wide Association Study for Type 2 Diabetes in Youth: The Progress in Diabetes Genetics in Youth (ProDiGY) Consortium
- (2021) Shylaja Srinivasan et al. DIABETES
- OGTT Glucose Response Curves, Insulin Sensitivity, and β-Cell Function in RISE: Comparison Between Youth and Adults at Randomization and in Response to Interventions to Preserve β-Cell Function
- (2021) Silva A. Arslanian et al. DIABETES CARE
- Pathophysiology-based subphenotyping of individuals at elevated risk for type 2 diabetes
- (2021) Robert Wagner et al. NATURE MEDICINE
- Pancreatic β-cell heterogeneity in health and diabetes: classes, sources, and subtypes
- (2021) Mario A Miranda et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Pancreatic beta cell autophagy is impaired in type 1 diabetes
- (2021) Charanya Muralidharan et al. DIABETOLOGIA
- Residual β cell function in long-term type 1 diabetes associates with reduced incidence of hypoglycemia
- (2021) Rose A. Gubitosi-Klug et al. JOURNAL OF CLINICAL INVESTIGATION
- Monogenic diabetes: a gateway to precision medicine in diabetes
- (2021) Haichen Zhang et al. JOURNAL OF CLINICAL INVESTIGATION
- Lumacaftor/ivacaftor in cystic fibrosis: effects on glucose metabolism and insulin secretion
- (2021) C. Colombo et al. JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
- Association of glycemia with insulin sensitivity and β-cell function in adults with early type 2 diabetes on metformin alone
- (2021) Kristina M. Utzschneider et al. JOURNAL OF DIABETES AND ITS COMPLICATIONS
- A Selective Look at Autophagy in Pancreatic β-Cells
- (2021) Gemma L. Pearson et al. DIABETES
- Genetic Susceptibility Determines β-Cell Function and Fasting Glycemia Trajectories Throughout Childhood: A 12-Year Cohort Study (EarlyBird 76)
- (2020) Jerome Carayol et al. DIABETES CARE
- Impaired counterregulatory responses to hypoglycaemia following oral glucose in adults with cystic fibrosis
- (2020) Moira L. Aitken et al. DIABETOLOGIA
- PAM haploinsufficiency does not accelerate the development of diet- and human IAPP-induced diabetes in mice
- (2020) Yi-Chun Chen et al. DIABETOLOGIA
- Insights into pancreatic islet cell dysfunction from type 2 diabetes mellitus genetics
- (2020) Nicole A. J. Krentz et al. Nature Reviews Endocrinology
- Trends in Incidence of Type 1 and Type 2 Diabetes Among Youths — Selected Counties and Indian Reservations, United States, 2002–2015
- (2020) Jasmin Divers et al. MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
- Patch-Seq Links Single-Cell Transcriptomes to Human Islet Dysfunction in Diabetes
- (2020) Joan Camunas-Soler et al. Cell Metabolism
- Revisiting Proinsulin Processing: Evidence That Human β-Cells Process Proinsulin With Prohormone Convertase (PC) 1/3 But Not PC2
- (2020) Adam Ramzy et al. DIABETES
- Pancreatic β-cells in type 1 and type 2 diabetes mellitus: different pathways to failure
- (2020) Décio L. Eizirik et al. Nature Reviews Endocrinology
- Pancreatic steatosis associates with impaired insulin secretion in genetically predisposed individuals
- (2020) Róbert Wagner et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Linearization of the Disposition Index equation allows evaluation of secretion-sensitivity coupling slopes
- (2020) Kieren J. Mather et al. JOURNAL OF DIABETES AND ITS COMPLICATIONS
- A Review of the Pathophysiology and Management of Diabetes in Pregnancy
- (2020) Aoife M. Egan et al. MAYO CLINIC PROCEEDINGS
- A combined risk score enhances prediction of type 1 diabetes among susceptible children
- (2020) Lauric A. Ferrat et al. NATURE MEDICINE
- Circulating unmethylated CHTOP and INS DNA fragments provide evidence of possible islet cell death in youth with obesity and diabetes
- (2020) Farooq Syed et al. Clinical Epigenetics
- A Long Non-coding RNA, LOC157273, Is an Effector Transcript at the Chromosome 8p23.1-PPP1R3B Metabolic Traits and Type 2 Diabetes Risk Locus
- (2020) Alisa K. Manning et al. Frontiers in Genetics
- Multiplexing DNA methylation markers to detect circulating cell-free DNA derived from human pancreatic β cells
- (2020) Daniel Neiman et al. JCI Insight
- Early beta cell dysfunction vs insulin hypersecretion as the primary event in the pathogenesis of dysglycaemia
- (2020) Nathalie Esser et al. DIABETOLOGIA
- Approach to the Patient with MODY-Monogenic Diabetes
- (2020) David T Broome et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Lumacaftor/ivacaftor therapy fails to increase insulin secretion in F508del/F508del CF patients
- (2020) Amir Moheet et al. Journal of Cystic Fibrosis
- β‐cells in youth with impaired glucose tolerance or early type 2 diabetes secrete more insulin and are more responsive than in adults
- (2020) Kristina M. Utzschneider et al. PEDIATRIC DIABETES
- Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D
- (2020) Ana Viñuela et al. Nature Communications
- Receptor occupancy of dual glucagon-like peptide 1/glucagon receptor agonist SAR425899 in individuals with type 2 diabetes
- (2020) Olof Eriksson et al. Scientific Reports
- Single-Cell Transcriptome Profiling Reveals β Cell Maturation in Stem Cell-Derived Islets after Transplantation
- (2020) Punn Augsornworawat et al. Cell Reports
- 2-year remission of type 2 diabetes and pancreas morphology: a post-hoc analysis of the DiRECT open-label, cluster-randomised trial
- (2020) Ahmad Al-Mrabeh et al. Lancet Diabetes & Endocrinology
- mRNA Processing: An Emerging Frontier in the Regulation of Pancreatic β Cell Function
- (2020) Nicole D. Moss et al. Frontiers in Genetics
- The healthy exocrine pancreas contains preproinsulin-specific CD8 T cells that attack islets in type 1 diabetes
- (2020) Christine Bender et al. Science Advances
- Paracrine and autocrine control of insulin secretion in human islets: evidence and pending questions
- (2020) Jean-Claude Henquin AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- 2. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes—2021
- (2020) DIABETES CARE
- Limitations of the fasting proinsulin to insulin ratio as a measure of β‐cell health in people with and without impaired glucose tolerance
- (2020) Aoife M. Egan et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- A Noncoding Variant Near PPP1R3B Promotes Liver Glycogen Storage and MetS, but Protects Against Myocardial Infarction
- (2020) Bratati Kahali et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Golimumab and Beta-Cell Function in Youth with New-Onset Type 1 Diabetes
- (2020) Teresa Quattrin et al. NEW ENGLAND JOURNAL OF MEDICINE
- CD4+CD25+CD127hi cell frequency predicts disease progression in type 1 diabetes
- (2020) Aditi Narsale et al. JCI Insight
- Probing the Meaning of Persistent Propeptide Release in Type 1 Diabetes
- (2019) Steven E. Kahn et al. DIABETES CARE
- Development and Standardization of an Improved Type 1 Diabetes Genetic Risk Score for Use in Newborn Screening and Incident Diagnosis
- (2019) Seth A. Sharp et al. DIABETES CARE
- The Central Role of Glucokinase in Glucose Homeostasis: A Perspective 50 Years After Demonstrating the Presence of the Enzyme in Islets of Langerhans
- (2019) Franz M. Matschinsky et al. Frontiers in Physiology
- Heterogeneous Expression of Proinsulin Processing Enzymes in Beta Cells of Non-diabetic and Type 2 Diabetic Humans
- (2019) Gladys Teitelman JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- Beta cells in type 1 diabetes: mass and function; sleeping or dead?
- (2019) Richard A. Oram et al. DIABETOLOGIA
- Epigenetics in Human Obesity and Type 2 Diabetes
- (2019) Charlotte Ling et al. Cell Metabolism
- Analysis of circulating lncRNA expression profiles in patients with diabetes mellitus and diabetic nephropathy: Differential expression profile of circulating lncRNA
- (2019) Ying Yang et al. CLINICAL NEPHROLOGY
- Predicting Islet Cell Autoimmunity and Type 1 Diabetes: An 8-Year TEDDY Study Progress Report
- (2019) Jeffrey P. Krischer et al. DIABETES CARE
- Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls
- (2019) Jason Flannick et al. NATURE
- Improving the Theranostic Potential of Exendin 4 by Reducing the Renal Radioactivity through Brush Border Membrane Enzyme-Mediated Degradation
- (2019) Mingru Zhang et al. BIOCONJUGATE CHEMISTRY
- Standardizing T-Cell Biomarkers in Type 1 Diabetes: Challenges and Recent Advances
- (2019) Simi Ahmed et al. DIABETES
- Cells Deploy a Two-Pronged Strategy to Rectify Misfolded Proinsulin Aggregates
- (2019) Corey N. Cunningham et al. MOLECULAR CELL
- Lysosomal degradation of newly formed insulin granules contributes to β cell failure in diabetes
- (2019) Adrien Pasquier et al. Nature Communications
- Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk
- (2019) William W. Greenwald et al. Nature Communications
- Serum miR-204 is an early biomarker of type 1 diabetes-associated pancreatic beta-cell loss
- (2019) Guanlan Xu et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Epigenome-Wide Association Study of Incident Type 2 Diabetes in a British Population: EPIC-Norfolk Study
- (2019) Alexia Cardona et al. DIABETES
- Glucolipotoxicity Alters Insulin Secretion via Epigenetic Changes in Human Islets
- (2019) Elin Hall et al. DIABETES
- Genetic Variants Predisposing Most Strongly to Type 1 Diabetes Diagnosed Under Age 7 Years Lie Near Candidate Genes That Function in the Immune System and in Pancreatic β-Cells
- (2019) Jamie R.J. Inshaw et al. DIABETES CARE
- WITHDRAWN: Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the International Diabetes Federation Diabetes Atlas, 9th edition
- (2019) Pouya Saeedi et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Intrauterine programming of obesity and type 2 diabetes
- (2019) Denise S. Fernandez-Twinn et al. DIABETOLOGIA
- Genetic Risk Scores for Diabetes Diagnosis and Precision Medicine
- (2019) Miriam S Udler et al. ENDOCRINE REVIEWS
- Exosomes and Their Noncoding RNA Cargo Are Emerging as New Modulators for Diabetes Mellitus
- (2019) Wenguang Chang et al. Cells
- Longitudinal Pattern of First-Phase Insulin Response Is Associated With Genetic Variants Outside the Class II HLA Region in Children With Multiple Autoantibodies
- (2019) Maarit K. Koskinen et al. DIABETES
- Maternal Gestational Diabetes Mellitus and Newborn DNA Methylation: Findings From the Pregnancy and Childhood Epigenetics Consortium
- (2019) Caitlin G. Howe et al. DIABETES CARE
- Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes
- (2019) Manuela Battaglia et al. DIABETES CARE
- Absence of Islet Autoantibodies and Modestly Raised Glucose Values at Diabetes Diagnosis Should Lead to Testing for MODY: Lessons From a 5-Year Pediatric Swedish National Cohort Study
- (2019) Annelie Carlsson et al. DIABETES CARE
- Profiling of RNAs from Human Islet-Derived Exosomes in a Model of Type 1 Diabetes
- (2019) Preethi Krishnan et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Genetic modifiers of cystic fibrosis-related diabetes have extensive overlap with type 2 diabetes and related traits
- (2019) Melis A Aksit et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Cystic fibrosis related diabetes: Pathophysiology, screening and diagnosis
- (2019) Andrea Granados et al. Journal of Cystic Fibrosis
- Micro(RNA) Management and Mismanagement of the Islet
- (2019) Lena Eliasson et al. JOURNAL OF MOLECULAR BIOLOGY
- Effects on pancreatic Beta and other Islet cells of the glucose-dependent insulinotropic polypeptide
- (2019) Rabeet Khan et al. PEPTIDES
- Abnormalities in proinsulin processing in islets from individuals with longstanding T1D
- (2019) Emily K. Sims et al. Translational Research
- MicroRNA Signatures as Future Biomarkers for Diagnosis of Diabetes States
- (2019) Srividya Vasu et al. Cells
- Understanding the complexity of socioeconomic disparities in type 2 diabetes risk: a study of 4.3 million people in Sweden
- (2019) Maria Wemrell et al. BMJ Open Diabetes Research & Care
- Single-cell ATAC-Seq in human pancreatic islets and deep learning upscaling of rare cells reveals cell-specific type 2 diabetes regulatory signatures
- (2019) Vivek Rai et al. Molecular Metabolism
- Obesity, metabolic disease and the pancreas—Quantitative imaging of pancreatic fat
- (2018) Naomi S Sakai et al. BRITISH JOURNAL OF RADIOLOGY
- The Pericyte of the Pancreatic Islet Regulates Capillary Diameter and Local Blood Flow
- (2018) Joana Almaça et al. Cell Metabolism
- Immune Recognition of β-Cells: Neoepitopes as Key Players in the Loss of Tolerance
- (2018) Eddie A. James et al. DIABETES
- Islet Long Noncoding RNAs: A Playbook for Discovery and Characterization
- (2018) Ruth A. Singer et al. DIABETES
- Islet Interleukin-1β Immunoreactivity Is an Early Feature of Cystic Fibrosis That May Contribute to β-Cell Failure
- (2018) Rebecca L. Hull et al. DIABETES CARE
- Metabolic Contrasts Between Youth and Adults With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes: I. Observations Using the Hyperglycemic Clamp
- (2018) DIABETES CARE
- Metabolic Contrasts Between Youth and Adults With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes: II. Observations Using the Oral Glucose Tolerance Test
- (2018) DIABETES CARE
- Impact of Insulin and Metformin Versus Metformin Alone on β-Cell Function in Youth With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes
- (2018) DIABETES CARE
- MicroRNA expression profile in plasma from type 1 diabetic patients: Case-control study and bioinformatic analysis
- (2018) Taís S. Assmann et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Meta-genome-wide association studies identify a locus on chromosome 1 and multiple variants in the MHC region for serum C-peptide in type 1 diabetes
- (2018) Delnaz Roshandel et al. DIABETOLOGIA
- Prospective evaluation of insulin and incretin dynamics in obese adults with and without diabetes for 2 years after Roux-en-Y gastric bypass
- (2018) Jonathan Q. Purnell et al. DIABETOLOGIA
- Beta cell extracellular vesicle miR-21-5p cargo is increased in response to inflammatory cytokines and serves as a biomarker of type 1 diabetes
- (2018) Alexander J. Lakhter et al. DIABETOLOGIA
- Decreased VMAT2 in the pancreas of humans with type 2 diabetes mellitus measured in vivo by PET imaging
- (2018) Gary W. Cline et al. DIABETOLOGIA
- Relationship between genetic variation at PPP1R3B and levels of liver glycogen and triglyceride
- (2018) Stefan Stender et al. HEPATOLOGY
- Identification of non-HLA genes associated with development of islet autoimmunity and type 1 diabetes in the prospective TEDDY cohort
- (2018) Ashok Sharma et al. JOURNAL OF AUTOIMMUNITY
- Anti-Inflammatory Therapy With Canakinumab for the Prevention and Management of Diabetes
- (2018) Brendan M. Everett et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes
- (2018) Anubha Mahajan et al. NATURE GENETICS
- Pancreatic β-Cell Electrical Activity and Insulin Secretion: Of Mice and Men
- (2018) Patrik Rorsman et al. PHYSIOLOGICAL REVIEWS
- Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: A prospective study in children
- (2018) Ezio Bonifacio et al. PLOS MEDICINE
- Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci
- (2018) Matthias Thurner et al. eLife
- Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables
- (2018) Emma Ahlqvist et al. Lancet Diabetes & Endocrinology
- Sex differences underlying pancreatic islet biology and its dysfunction
- (2018) Maureen Gannon et al. Molecular Metabolism
- Cystic Fibrosis-Related Diabetes
- (2018) Kayani Kayani et al. Frontiers in Endocrinology
- Conventional and Neo-Antigenic Peptides Presented by β Cells Are Targeted by Circulating Naïve CD8+ T Cells in Type 1 Diabetic and Healthy Donors
- (2018) Sergio Gonzalez-Duque et al. Cell Metabolism
- Increased Beta Cell Workload Modulates Proinsulin/Insulin Ratio in Humans
- (2018) Teresa Mezza et al. DIABETES
- Type 2 Diabetes Associated Genetic Variants Regulate Chromatin Accessibility in Human Islets
- (2018) Shubham Khetan et al. DIABETES
- Islet prohormone processing in health and disease
- (2018) Yi-Chun Chen et al. DIABETES OBESITY & METABOLISM
- Use of the PET ligand florbetapir for in vivo imaging of pancreatic islet amyloid deposits in hIAPP transgenic mice
- (2018) Andrew T. Templin et al. DIABETOLOGIA
- Biomarkers of islet beta cell stress and death in type 1 diabetes
- (2018) Emily K. Sims et al. DIABETOLOGIA
- Immunological biomarkers for the development and progression of type 1 diabetes
- (2018) Chantal Mathieu et al. DIABETOLOGIA
- Novel epigenetic-sensitive clinical challenges both in type 1 and type 2 diabetes
- (2018) Linda Sommese et al. JOURNAL OF DIABETES AND ITS COMPLICATIONS
- A pilot study of pancreatic islet amyloid PET imaging with [18F]FDDNP
- (2018) Zhi Lu et al. NUCLEAR MEDICINE COMMUNICATIONS
- A Global Perspective of Latent Autoimmune Diabetes in Adults
- (2018) Rajashree Mishra et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis
- (2018) Miriam S. Udler et al. PLOS MEDICINE
- Ketosis-Prone Diabetes (Flatbush Diabetes): an Emerging Worldwide Clinically Important Entity
- (2018) Harold E. Lebovitz et al. Current Diabetes Reports
- Diabetes and HIV
- (2018) Emile Camille Noubissi et al. Current Diabetes Reports
- Low Level Insulin Content Within Abundant Non-Beta Islet Endocrine Cells in Long-Standing Type 1 Diabetes
- (2018) Carol J. Lam et al. DIABETES
- GLP-1 Receptor in Pancreatic α-Cells Regulates Glucagon Secretion in a Glucose-Dependent Bidirectional Manner
- (2018) Yanqing Zhang et al. DIABETES
- Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes
- (2018) Emily K. Sims et al. DIABETES CARE
- The Shape of the Glucose Response Curve During an Oral Glucose Tolerance Test: Forerunner of Heightened Glycemic Failure Rates and Accelerated Decline in β-Cell Function in TODAY
- (2018) Silva Arslanian et al. DIABETES CARE
- Neoepitopes: a new take on beta cell autoimmunity in type 1 diabetes
- (2018) Stuart I. Mannering et al. DIABETOLOGIA
- Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps
- (2018) Anubha Mahajan et al. NATURE GENETICS
- Variation in Maturity-Onset Diabetes of the Young Genes Influence Response to Interventions for Diabetes Prevention
- (2017) Liana K Billings et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Measurement of Pro-Islet Amyloid Polypeptide (1–48) in Diabetes and Islet Transplants
- (2017) Jaques A. Courtade et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Assessment of β Cell Mass and Function by AIRmax and Intravenous Glucose in High-Risk Subjects for Type 1 Diabetes
- (2017) Wei Hao et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling
- (2017) Chunhua Dai et al. JOURNAL OF CLINICAL INVESTIGATION
- Autoreactive T cells in type 1 diabetes
- (2017) Alberto Pugliese JOURNAL OF CLINICAL INVESTIGATION
- Discovery, characterization, and clinical development of the glucagon-like peptides
- (2017) Daniel J. Drucker et al. JOURNAL OF CLINICAL INVESTIGATION
- Shape of the OGTT glucose curve and risk of impaired glucose metabolism in the EGIR-RISC cohort
- (2017) Melania Manco et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Autoimmunity against a defective ribosomal insulin gene product in type 1 diabetes
- (2017) Maria J L Kracht et al. NATURE MEDICINE
- Adult-onset autoimmune diabetes: current knowledge and implications for management
- (2017) Raffaella Buzzetti et al. Nature Reviews Endocrinology
- CF-related diabetes: Containing the metabolic miscreant of cystic fibrosis
- (2017) Amir Moheet et al. PEDIATRIC PULMONOLOGY
- A divergent population of autoantigen-responsive CD4 + T cells in infants prior to β cell autoimmunity
- (2017) Anne-Kristin Heninger et al. Science Translational Medicine
- Metabolic and immune effects of immunotherapy with proinsulin peptide in human new-onset type 1 diabetes
- (2017) Mohammad Alhadj Ali et al. Science Translational Medicine
- Heterozygous RFX6 protein truncating variants are associated with MODY with reduced penetrance
- (2017) Kashyap A. Patel et al. Nature Communications
- Analysis of inflammatory cytokine and TLR expression levels in Type 2 Diabetes with complications
- (2017) Saket Gupta et al. Scientific Reports
- Type 1 Diabetes Candidate Genes Linked to Pancreatic Islet Cell Inflammation and Beta-Cell Apoptosis
- (2017) Joachim Størling et al. Genes
- Radioiodinated Exendin-4 Is Superior to the Radiometal-Labelled Glucagon-Like Peptide-1 Receptor Probes Overcoming Their High Kidney Uptake
- (2017) Tilman Läppchen et al. PLoS One
- Pancreatic fat content by magnetic resonance imaging in subjects with prediabetes, diabetes, and controls from a general population without cardiovascular disease
- (2017) Sophia D. Heber et al. PLoS One
- Pancreatic size and fat content in diabetes: A systematic review and meta-analysis of imaging studies
- (2017) Tiago Severo Garcia et al. PLoS One
- Distinct fecal and oral microbiota composition in human type 1 diabetes, an observational study
- (2017) Pieter F. de Groot et al. PLoS One
- Plasma-derived exosome characterization reveals a distinct microRNA signature in long duration Type 1 diabetes
- (2017) Marta Garcia-Contreras et al. Scientific Reports
- CFTR silencing in pancreatic β-cells reveals a functional impact on glucose-stimulated insulin secretion and oxidative stress response
- (2016) Thierry Ntimbane et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Development of 99mTc-Labeled Pyridyl Benzofuran Derivatives To Detect Pancreatic Amylin in Islet Amyloid Model Mice
- (2016) Masashi Yoshimura et al. BIOCONJUGATE CHEMISTRY
- Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes
- (2016) Åsa Segerstolpe et al. Cell Metabolism
- Antithymocyte Globulin Plus G-CSF Combination Therapy Leads to Sustained Immunomodulatory and Metabolic Effects in a Subset of Responders With Established Type 1 Diabetes
- (2016) Michael J. Haller et al. DIABETES
- Differential Insulitic Profiles Determine the Extent of β-Cell Destruction and the Age at Onset of Type 1 Diabetes
- (2016) Pia Leete et al. DIABETES
- SERCA2 Deficiency Impairs Pancreatic β-Cell Function in Response to Diet-Induced Obesity
- (2016) Xin Tong et al. DIABETES
- Next-Generation Sequencing Reveals ThatHLA-DRB3,-DRB4, and-DRB5May Be Associated With Islet Autoantibodies and Risk for Childhood Type 1 Diabetes
- (2016) Lue Ping Zhao et al. DIABETES
- Type 1 Diabetes Genetic Risk Score: A Novel Tool to Discriminate Monogenic and Type 1 Diabetes
- (2016) Kashyap A. Patel et al. DIABETES
- Primary Human and Rat β-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity
- (2016) Chiara Cianciaruso et al. DIABETES
- Elevations in the Fasting Serum Proinsulin–to–C-Peptide Ratio Precede the Onset of Type 1 Diabetes
- (2016) Emily K. Sims et al. DIABETES CARE
- Lack of Independent Association Between Fatty Pancreas and Incidence of Type 2 Diabetes: 5-Year Japanese Cohort Study
- (2016) Hajime Yamazaki et al. DIABETES CARE
- Reversion of β-Cell Autoimmunity Changes Risk of Type 1 Diabetes: TEDDY Study
- (2016) Kendra Vehik et al. DIABETES CARE
- Loss of prohormone convertase 2 promotes beta cell dysfunction in a rodent transplant model expressing human pro-islet amyloid polypeptide
- (2016) Jaques A. Courtade et al. DIABETOLOGIA
- Morphology of the pancreas in type 2 diabetes: effect of weight loss with or without normalisation of insulin secretory capacity
- (2016) Ahmad Al-Mrabeh et al. DIABETOLOGIA
- Autophagy is a major regulator of beta cell insulin homeostasis
- (2016) Yael Riahi et al. DIABETOLOGIA
- Interleukin-1 antagonism moderates the inflammatory state associated with Type 1 diabetes during clinical trials conducted at disease onset
- (2016) Susanne M. Cabrera et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- T cells in type 1 diabetes: Instructors, regulators and effectors: A comprehensive review
- (2016) Iria Gomez-Tourino et al. JOURNAL OF AUTOIMMUNITY
- Glucagon-Like Peptide-1 Receptor PET/CT with 68Ga-NOTA-Exendin-4 for Detecting Localized Insulinoma: A Prospective Cohort Study
- (2016) Y. Luo et al. JOURNAL OF NUCLEAR MEDICINE
- Approaches to Improve the Pharmacokinetics of Radiolabeled Glucagon-Like Peptide-1 Receptor Ligands Using Antagonistic Tracers
- (2016) S. N. Rylova et al. JOURNAL OF NUCLEAR MEDICINE
- Genetic risk factors for type 1 diabetes
- (2016) Flemming Pociot et al. LANCET
- Long-Term Outcomes of Biliopancreatic Diversion on Glycemic Control, Insulin Sensitivity and Beta Cell Function
- (2016) Ana Carolina Junqueira Vasques et al. OBESITY SURGERY
- Insulitis in the pathogenesis of type 1 diabetes
- (2016) Alberto Pugliese PEDIATRIC DIABETES
- Genetic susceptibility to type 1 diabetes in childhood - estimation of HLA class II associated disease risk and class II effect in various phases of islet autoimmunity
- (2016) J Ilonen et al. PEDIATRIC DIABETES
- Identification of tissue-specific cell death using methylation patterns of circulating DNA
- (2016) Roni Lehmann-Werman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion
- (2016) T. Delong et al. SCIENCE
- Use of the Electronic Medical Record to Assess Pancreas Size in Type 1 Diabetes
- (2016) John Virostko et al. PLoS One
- Prediction of Impending Type 1 Diabetes through Automated Dual-Label Measurement of Proinsulin:C-Peptide Ratio
- (2016) Annelien Van Dalem et al. PLoS One
- Distinct Roles of β-Cell Mass and Function During Type 1 Diabetes Onset and Remission
- (2015) Helena Chmelova et al. DIABETES
- Function of Isolated Pancreatic Islets From Patients at Onset of Type 1 Diabetes: Insulin Secretion Can Be Restored After Some Days in a Nondiabetogenic Environment In Vitro
- (2015) Lars Krogvold et al. DIABETES
- Insulitis and β-Cell Mass in the Natural History of Type 1 Diabetes
- (2015) Martha Campbell-Thompson et al. DIABETES
- Predicting Type 1 Diabetes Using Biomarkers
- (2015) Ezio Bonifacio DIABETES CARE
- A Type 1 Diabetes Genetic Risk Score Can Aid Discrimination Between Type 1 and Type 2 Diabetes in Young Adults
- (2015) Richard A. Oram et al. DIABETES CARE
- Pancreatic adipose tissue infiltration, parenchymal steatosis and beta cell function in humans
- (2015) Paul Begovatz et al. DIABETOLOGIA
- The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study
- (2015) Jeffrey P. Krischer et al. DIABETOLOGIA
- Epigenome-wide association study identifiesTXNIPgene associated with type 2 diabetes mellitus and sustained hyperglycemia
- (2015) Carolina Soriano-Tárraga et al. HUMAN MOLECULAR GENETICS
- Non-HLA gene effects on the disease process of type 1 diabetes: From HLA susceptibility to overt disease
- (2015) Johanna Lempainen et al. JOURNAL OF AUTOIMMUNITY
- β Cell death and dysfunction during type 1 diabetes development in at-risk individuals
- (2015) Kevan C. Herold et al. JOURNAL OF CLINICAL INVESTIGATION
- Preoperative β-cell function in patients with type 2 diabetes is important for the outcome of Roux-en-Y gastric bypass surgery
- (2015) Michael Taulo Lund et al. JOURNAL OF PHYSIOLOGY-LONDON
- The effect of early, comprehensive genomic testing on clinical care in neonatal diabetes: an international cohort study
- (2015) Elisa De Franco et al. LANCET
- Cross-sectional and Test-Retest Characterization of PET with [18F]FP-(+)-DTBZ for β Cell Mass Estimates in Diabetes
- (2015) Matthew J. Freeby et al. MOLECULAR IMAGING AND BIOLOGY
- Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers
- (2015) Suna Onengut-Gumuscu et al. NATURE GENETICS
- Urocortin3 mediates somatostatin-dependent negative feedback control of insulin secretion
- (2015) Talitha van der Meulen et al. NATURE MEDICINE
- Altered Volume, Morphology and Composition of the Pancreas in Type 2 Diabetes
- (2015) Mavin Macauley et al. PLoS One
- Noninvasive mapping of pancreatic inflammation in recent-onset type-1 diabetes patients
- (2015) Jason L. Gaglia et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aged insulin granules display reduced microtubule-dependent mobility and are disposed within actin-positive multigranular bodies
- (2015) Peter Hoboth et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pancreatic Steatosis Demonstrated at MR Imaging in the General Population: Clinical Relevance
- (2015) Jens-Peter Kühn et al. RADIOLOGY
- Insulin secretion in patients with latent autoimmune diabetes (LADA): half way between type 1 and type 2 diabetes: action LADA 9
- (2015) Marta Hernandez et al. BMC Endocrine Disorders
- Genetics of Type 2 Diabetes—Pitfalls and Possibilities
- (2015) Rashmi Prasad et al. Genes
- Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study
- (2015) John C Chambers et al. Lancet Diabetes & Endocrinology
- Type 2 diabetes mellitus
- (2015) Ralph A. DeFronzo et al. Nature Reviews Disease Primers
- Association between Family History Risk Categories and Prevalence of Diabetes in Chinese Population
- (2015) Jinping Zhang et al. PLoS One
- Both Fasting and Glucose-Stimulated Proinsulin Levels Predict Hyperglycemia and Incident Type 2 Diabetes: A Population-Based Study of 9,396 Finnish Men
- (2015) Jagadish Vangipurapu et al. PLoS One
- Differences in pancreatic volume, fat content, and fat density measured by multidetector-row computed tomography according to the duration of diabetes
- (2014) Soo Lim et al. ACTA DIABETOLOGICA
- Fatty Pancreas, Insulin Resistance and β-Cell Function: A Population Study Using Fat-Water Magnetic Resonance Imaging
- (2014) Vincent Wai-Sun Wong et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Adverse Epigenetic Signatures by Histone Methyltransferase Set7 Contribute to Vascular Dysfunction in Patients With Type 2 Diabetes MellitusCLINICAL PERSPECTIVE
- (2014) Francesco Paneni et al. Circulation-Cardiovascular Genetics
- Role of Type 1 Diabetes–Associated SNPs on Risk of Autoantibody Positivity in the TEDDY Study
- (2014) Carina Törn et al. DIABETES
- β-Cell Function, Incretin Effect, and Incretin Hormones in Obese Youth Along the Span of Glucose Tolerance From Normal to Prediabetes to Type 2 Diabetes
- (2014) Sara F. Michaliszyn et al. DIABETES
- Reduction in CD4 Central Memory T-Cell Subset in Costimulation Modulator Abatacept-Treated Patients With Recent-Onset Type 1 Diabetes Is Associated With Slower C-Peptide Decline
- (2014) T. Orban et al. DIABETES
- Impact of Islet Autoimmunity on the Progressive β-Cell Functional Decline in Type 2 Diabetes
- (2014) Barbara M. Brooks-Worrell et al. DIABETES CARE
- Insulin secretion measured by stimulated C-peptide in long-established Type 1 diabetes in the Diabetes Control and Complications Trial (DCCT)/ Epidemiology of Diabetes Interventions and Complications (EDIC) cohort: a pilot study
- (2014) P. McGee et al. DIABETIC MEDICINE
- Association of proinflammatory cytokines and islet resident leucocytes with islet dysfunction in type 2 diabetes
- (2014) Matthew J. Butcher et al. DIABETOLOGIA
- Non-invasive quantification of the beta cell mass by SPECT with 111In-labelled exendin
- (2014) Maarten Brom et al. DIABETOLOGIA
- Islet amyloid formation is an important determinant for inducing islet inflammation in high-fat-fed human IAPP transgenic mice
- (2014) Daniel T. Meier et al. DIABETOLOGIA
- Feature ranking of type 1 diabetes susceptibility genes improves prediction of type 1 diabetes
- (2014) Christiane Winkler et al. DIABETOLOGIA
- Estimated proinsulin processing activity of prohormone convertase (PC) 1/3 rather than PC2 is decreased in pancreatic ^|^beta;-cells of type 2 diabetic patients
- (2014) Sachihiko Ozawa et al. ENDOCRINE JOURNAL
- The Influence of Rare Genetic Variation inSLC30A8on Diabetes Incidence and β-Cell Function
- (2014) Liana K. Billings et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes
- (2014) Valgerdur Steinthorsdottir et al. NATURE GENETICS
- Islet Remodeling in Female Mice with Spontaneous Autoimmune and Streptozotocin-Induced Diabetes
- (2014) Annette Plesner et al. PLoS One
- Zinc transporter 8 (ZnT8) and β cell function
- (2014) Howard W. Davidson et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Biomarkers in type 1 diabetes
- (2014) James E. Tooley et al. Current Opinion in Endocrinology Diabetes and Obesity
- Glucose-induced electrical activities and insulin secretion in pancreatic islet β-cells are modulated by CFTR
- (2014) Jing Hui Guo et al. Nature Communications
- Feasibility of Amylin Imaging in Pancreatic Islets with β-Amyloid Imaging Probes
- (2014) Masashi Yoshimura et al. Scientific Reports
- Decreased miR-146 expression in peripheral blood mononuclear cells is correlated with ongoing islet autoimmunity in type 1 diabetes patients 1型糖尿病患者外周血单个核细胞miR-146表达下调与胰岛持续免疫失衡相关
- (2014) Minglan Yang et al. Journal of Diabetes
- Genome-Wide Associations between Genetic and Epigenetic Variation Influence mRNA Expression and Insulin Secretion in Human Pancreatic Islets
- (2014) Anders H. Olsson et al. PLoS Genetics
- Genome-Wide DNA Methylation Analysis of Human Pancreatic Islets from Type 2 Diabetic and Non-Diabetic Donors Identifies Candidate Genes That Influence Insulin Secretion
- (2014) Tasnim Dayeh et al. PLoS Genetics
- Metabolic Signaling in Fuel-Induced Insulin Secretion
- (2013) Marc Prentki et al. Cell Metabolism
- Class II Major Histocompatibility Complex Plays an Essential Role in Obesity-Induced Adipose Inflammation
- (2013) Tuo Deng et al. Cell Metabolism
- Novel Diabetes Autoantibodies and Prediction of Type 1 Diabetes
- (2013) Janet M. Wenzlau et al. Current Diabetes Reports
- Resident Macrophages Mediate Islet Amyloid Polypeptide–Induced Islet IL-1β Production and β-Cell Dysfunction
- (2013) Clara Y. Westwell-Roper et al. DIABETES
- Acceleration of the Loss of the First-Phase Insulin Response During the Progression to Type 1 Diabetes in Diabetes Prevention Trial-Type 1 Participants
- (2013) J. M. Sosenko et al. DIABETES
- Next Generation Sequencing Reveals the Association of DRB3*02:02 With Type 1 Diabetes
- (2013) H. A. Erlich et al. DIABETES
- Death and Dysfunction of Transplanted -Cells: Lessons Learned From Type 2 Diabetes?
- (2013) K. J. Potter et al. DIABETES
- Patterns of -Cell Autoantibody Appearance and Genetic Associations During the First Years of Life
- (2013) J. Ilonen et al. DIABETES
- Genetic Risk of Progression to Type 2 Diabetes and Response to Intensive Lifestyle or Metformin in Prediabetic Women With and Without a History of Gestational Diabetes Mellitus
- (2013) Shannon D. Sullivan et al. DIABETES CARE
- Endocrine Secretory Reserve and Proinsulin Processing in Recipients of Islet of Langerhans Versus Whole Pancreas Transplants
- (2013) N. M. Elkhafif et al. DIABETES CARE
- Cost-Effectiveness of MODY Genetic Testing: Translating Genomic Advances Into Practical Health Applications
- (2013) Rochelle N. Naylor et al. DIABETES CARE
- Can New-Onset Diabetes After Kidney Transplant Be Prevented?
- (2013) H. A. Chakkera et al. DIABETES CARE
- Age-dependent decline of β-cell function in type 1 diabetes after diagnosis: a multi-centre longitudinal study
- (2013) A. Barker et al. DIABETES OBESITY & METABOLISM
- Steroid-induced diabetes: a clinical and molecular approach to understanding and treatment
- (2013) Jessica L. Hwang et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- The majority of patients with long-duration type 1 diabetes are insulin microsecretors and have functioning beta cells
- (2013) Richard A. Oram et al. DIABETOLOGIA
- Seroconversion to Multiple Islet Autoantibodies and Risk of Progression to Diabetes in Children
- (2013) Anette G. Ziegler et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Roux-en-Y Gastric Bypass and Sleeve Gastrectomy: Mechanisms of Diabetes Remission and Role of Gut Hormones
- (2013) M. Nannipieri et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- The relative associations of β-cell function and insulin sensitivity with glycemic status and incident glycemic progression in migrant Asian Indians in the United States: The MASALA study
- (2013) Unjali P. Gujral et al. JOURNAL OF DIABETES AND ITS COMPLICATIONS
- Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future
- (2013) Steven E Kahn et al. LANCET
- Improving prediction of type 1 diabetes by testing non-HLA genetic variants in addition to HLA markers
- (2013) Andrea K Steck et al. PEDIATRIC DIABETES
- Regional Differences in Islet Distribution in the Human Pancreas - Preferential Beta-Cell Loss in the Head Region in Patients with Type 2 Diabetes
- (2013) Xiaojun Wang et al. PLoS One
- Impact of Three Oral Antidiabetic Drugs on Markers of β-Cell Function in Patients with Type 2 Diabetes: A Meta-Analysis
- (2013) Jin Lu et al. PLoS One
- Vesicular monoamine transporter, type 2 (vmat2) expression as it compares to insulin and pancreatic polypeptide in the head, body and tail of the human pancreas
- (2013) Matthew Freeby et al. Islets
- Environmental Triggers of Type 1 Diabetes
- (2013) M. Knip et al. Cold Spring Harbor Perspectives in Medicine
- Antigen Targets of Type 1 Diabetes Autoimmunity
- (2013) B. O. Roep et al. Cold Spring Harbor Perspectives in Medicine
- GLIS3, a Susceptibility Gene for Type 1 and Type 2 Diabetes, Modulates Pancreatic Beta Cell Apoptosis via Regulation of a Splice Variant of the BH3-Only Protein Bim
- (2013) Tatiane C. Nogueira et al. PLoS Genetics
- Glucagon-like peptide-1 receptor imaging for the localisation of insulinomas: a prospective multicentre imaging study
- (2013) Emanuel Christ et al. Lancet Diabetes & Endocrinology
- Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure
- (2012) Chutima Talchai et al. CELL
- Saturated Fatty Acid and TLR Signaling Link β Cell Dysfunction and Islet Inflammation
- (2012) Kosei Eguchi et al. Cell Metabolism
- Attenuation of islet-specific T cell responses is associated with C-peptide improvement in autoimmune type 2 diabetes patients
- (2012) B. M. Brooks-Worrell et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- HLA-B7-Restricted Islet Epitopes Are Differentially Recognized in Type 1 Diabetic Children and Adults and Form Weak Peptide-HLA Complexes
- (2012) M. Scotto et al. DIABETES
- Transgenerational Glucose Intolerance WithIgf2/H19Epigenetic Alterations in Mouse Islet Induced by Intrauterine Hyperglycemia
- (2012) Guo-Lian Ding et al. DIABETES
- Islet -Cell Endoplasmic Reticulum Stress Precedes the Onset of Type 1 Diabetes in the Nonobese Diabetic Mouse Model
- (2012) S. A. Tersey et al. DIABETES
- Expression of endoplasmic reticulum stress markers in the islets of patients with type 1 diabetes
- (2012) I. Marhfour et al. DIABETOLOGIA
- DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients
- (2012) Michael Volkmar et al. EMBO JOURNAL
- Translational Control of Glucose-Induced Islet Amyloid Polypeptide Production in Pancreatic Islets
- (2012) Cristina Alarcon et al. ENDOCRINOLOGY
- Glucagon-like peptide-1 receptor imaging with [Lys40(Ahx-HYNIC-99mTc/EDDA)NH2]-exendin-4 for the detection of insulinoma
- (2012) Anna Sowa-Staszczak et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- A strategy for combining minor genetic susceptibility genes to improve prediction of disease in type 1 diabetes
- (2012) C Winkler et al. GENES AND IMMUNITY
- Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients
- (2012) Ken T. Coppieters et al. JOURNAL OF EXPERIMENTAL MEDICINE
- In Vivo Imaging of Endogenous Pancreatic -Cell Mass in Healthy and Type 1 Diabetic Subjects Using 18F-Fluoropropyl-Dihydrotetrabenazine and PET
- (2012) M. D. Normandin et al. JOURNAL OF NUCLEAR MEDICINE
- Brain Amyloid Imaging — FDA Approval of Florbetapir F18 Injection
- (2012) Lucie Yang et al. NEW ENGLAND JOURNAL OF MEDICINE
- β-Cell Loss and β-Cell Apoptosis in Human Type 2 Diabetes Are Related to Islet Amyloid Deposition
- (2011) Catherine A. Jurgens et al. AMERICAN JOURNAL OF PATHOLOGY
- Genetics of the HLA Region in the Prediction of Type 1 Diabetes
- (2011) Janelle A. Noble et al. Current Diabetes Reports
- Effects of Rosiglitazone, Glyburide, and Metformin on -Cell Function and Insulin Sensitivity in ADOPT
- (2011) S. E. Kahn et al. DIABETES
- Updated Genetic Score Based on 34 Confirmed Type 2 Diabetes Loci Is Associated With Diabetes Incidence and Regression to Normoglycemia in the Diabetes Prevention Program
- (2011) M.-F. Hivert et al. DIABETES
- Abnormal DNA methylation in CD4+ T cells from people with latent autoimmune diabetes in adults
- (2011) Yijun Li et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Exendin-4 increases islet amyloid deposition but offsets the resultant beta cell toxicity in human islet amyloid polypeptide transgenic mouse islets
- (2011) K. Aston-Mourney et al. DIABETOLOGIA
- Value of the radiolabelled GLP-1 receptor antagonist exendin(9–39) for targeting of GLP-1 receptor-expressing pancreatic tissues in mice and humans
- (2011) Beatrice Waser et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Pathogenesis of Type 1 Diabetes: Implications for Incidence Trends
- (2011) Mikael Knip Hormone Research in Paediatrics
- The Role of β-Cell Function and Insulin Sensitivity in the Remission of Type 2 Diabetes after Gastric Bypass Surgery
- (2011) M. Nannipieri et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Dynamics of insulin secretion and the clinical implications for obesity and diabetes
- (2011) Susumu Seino et al. JOURNAL OF CLINICAL INVESTIGATION
- Increased T Cell Proliferative Responses to Islet Antigens Identify Clinical Responders to Anti-CD20 Monoclonal Antibody (Rituximab) Therapy in Type 1 Diabetes
- (2011) K. C. Herold et al. JOURNAL OF IMMUNOLOGY
- IL-1 Blockade Attenuates Islet Amyloid Polypeptide-Induced Proinflammatory Cytokine Release and Pancreatic Islet Graft Dysfunction
- (2011) C. Westwell-Roper et al. JOURNAL OF IMMUNOLOGY
- GLUT2 (SLC2A2) is not the principal glucose transporter in human pancreatic beta cells: Implications for understanding genetic association signals at this locus
- (2011) Laura J. McCulloch et al. MOLECULAR GENETICS AND METABOLISM
- Improved Quantification of Islet Transplants by Magnetic Resonance Imaging With Resovist
- (2011) Ki-Soo Park et al. PANCREAS
- Islet Amyloid Polypeptide, Islet Amyloid, and Diabetes Mellitus
- (2011) Per Westermark et al. PHYSIOLOGICAL REVIEWS
- Detection of cell death in diabetes using differentially methylated circulating DNA
- (2011) E. M. Akirav et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Serum levels of proamylin and amylin in normal subjects and patients with impaired glucose regulation and type 2 diabetes mellitus
- (2010) Xiaoya Zheng et al. ACTA DIABETOLOGICA
- Isolation and preservation of peripheral blood mononuclear cells for analysis of islet antigen-reactive T cell responses: position statement of the T-Cell Workshop Committee of the Immunology of Diabetes Society
- (2010) R. Mallone et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Naturally Arising Human CD4 T-Cells That Recognize Islet Autoantigens and Secrete Interleukin-10 Regulate Proinflammatory T-Cell Responses via Linked Suppression
- (2010) T. I. M. Tree et al. DIABETES
- Residual Insulin Production and Pancreatic -Cell Turnover After 50 Years of Diabetes: Joslin Medalist Study
- (2010) H. A. Keenan et al. DIABETES
- Identification of Autoantibody-Negative Autoimmune Type 2 Diabetic Patients
- (2010) B. M. Brooks-Worrell et al. DIABETES CARE
- The shape of plasma glucose concentration curve during OGTT predicts future risk of type 2 diabetes
- (2010) Muhammad A. Abdul-Ghani et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- Pancreatic fat is negatively associated with insulin secretion in individuals with impaired fasting glucose and/or impaired glucose tolerance: a nuclear magnetic resonance study
- (2010) Martin Heni et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- Toxic oligomers and islet beta cell death: guilty by association or convicted by circumstantial evidence?
- (2010) S. Zraika et al. DIABETOLOGIA
- Proinsulin levels in patients with pancreatic diabetes are associated with functional changes in insulin secretion rather than pancreatic β-cell area
- (2010) Thomas G K Breuer et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- β-Cell Secretory Capacity and Demand in Recipients of Islet, Pancreas, and Kidney Transplants
- (2010) Michael R. Rickels et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Ectopic Fat Storage in the Pancreas, Liver, and Abdominal Fat Depots: Impact on β-Cell Function in Individuals with Impaired Glucose Metabolism
- (2010) N. J. van der Zijl et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Noninvasive imaging of pancreatic islet inflammation in type 1A diabetes patients
- (2010) Jason L. Gaglia et al. JOURNAL OF CLINICAL INVESTIGATION
- Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes
- (2010) Seth L Masters et al. NATURE IMMUNOLOGY
- Binding characteristics of 9-fluoropropyl-(+)-dihydrotetrabenzazine (AV-133) to the vesicular monoamine transporter type 2 in rats
- (2010) Hsin-Hsin Tsao et al. NUCLEAR MEDICINE AND BIOLOGY
- Evaluation of Fasting State-/Oral Glucose Tolerance Test-Derived Measures of Insulin Release for the Detection of Genetically Impaired β-Cell Function
- (2010) Silke A. Herzberg-Schäfer et al. PLoS One
- Magnetic Resonance Imaging of Pancreatic Islets Transplanted Into the Liver in Humans
- (2010) František Saudek et al. TRANSPLANTATION
- Secondary diabetes associated with principal endocrinopathies: the impact of new treatment modalities
- (2009) Eugenia Resmini et al. ACTA DIABETOLOGICA
- Impaired Proinsulin Processing is a Characteristic of Transplanted Islets
- (2009) A. M. Klimek et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Positron Emission Tomography in Clinical Islet Transplantation
- (2009) O. Eriksson et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Disproportionate Hyperproinsulinemia, β-Cell Restricted Prohormone Convertase 2 Deficiency, and Cell Cycle Inhibitors Expression by Human Islets Transplanted into Athymic Nude Mice: Insights into Nonimmune-Mediated Mechanisms of Delayed Islet Graft Failure
- (2009) Alberto M. Davalli et al. CELL TRANSPLANTATION
- Different Effects of FK506, Rapamycin, and Mycophenolate Mofetil on Glucose-Stimulated Insulin Release and Apoptosis in Human Islets
- (2009) James D. Johnson et al. CELL TRANSPLANTATION
- In vivovisualization of transplanted pancreatic islets by MRI: comparison betweenin vivo, histological and electron microscopy findings
- (2009) Pasquina Marzola et al. Contrast Media & Molecular Imaging
- Changes in Insulin Sensitivity and Insulin Release in Relation to Glycemia and Glucose Tolerance in 6,414 Finnish Men
- (2009) A. Stancakova et al. DIABETES
- From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus
- (2009) R. A. DeFronzo DIABETES
- Regression From Pre-Diabetes to Normal Glucose Regulation in the Diabetes Prevention Program
- (2009) L. Perreault et al. DIABETES CARE
- Preservation of -Cell Function in Autoantibody-Positive Youth With Diabetes
- (2009) C. J. Greenbaum et al. DIABETES CARE
- Evaluation of proposed oral disposition index measures in relation to the actual disposition index
- (2009) R. Retnakaran et al. DIABETIC MEDICINE
- Autophagy in human type 2 diabetes pancreatic beta cells
- (2009) M. Masini et al. DIABETOLOGIA
- Glucagon-Like Peptide-1 Receptor Imaging for Localization of Insulinomas
- (2009) Emanuel Christ et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Trajectories of glycaemia, insulin sensitivity, and insulin secretion before diagnosis of type 2 diabetes: an analysis from the Whitehall II study
- (2009) Adam G Tabák et al. LANCET
- Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
- (2009) Jeffrey C Barrett et al. NATURE GENETICS
- The role of inflammation in insulitis and β-cell loss in type 1 diabetes
- (2009) Décio L. Eizirik et al. Nature Reviews Endocrinology
- Clinical Magnetic Resonance Imaging of Pancreatic Islet Grafts After Iron Nanoparticle Labeling
- (2008) C. Toso et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Autoantibodies in type 1 diabetes
- (2008) Craig E. Taplin et al. AUTOIMMUNITY
- Analysis of islet inflammation in human type 1 diabetes
- (2008) A. Willcox et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- HLA DR-DQ Haplotypes and Genotypes and Type 1 Diabetes Risk: Analysis of the Type 1 Diabetes Genetics Consortium Families
- (2008) H. Erlich et al. DIABETES
- Lymphocytes From Patients With Type 1 Diabetes Display a Distinct Profile of Chromatin Histone H3 Lysine 9 Dimethylation: An Epigenetic Study in Diabetes
- (2008) F. Miao et al. DIABETES
- Oral Disposition Index Predicts the Development of Future Diabetes Above and Beyond Fasting and 2-h Glucose Levels
- (2008) K. M. Utzschneider et al. DIABETES CARE
- Genetic Determinants and Epidemiology of Cystic Fibrosis-Related Diabetes: Results from a British cohort of children and adults
- (2008) A. I. Adler et al. DIABETES CARE
- Primary Defects in -Cell Function Further Exacerbated by Worsening of Insulin Resistance Mark the Development of Impaired Glucose Tolerance in Obese Adolescents
- (2008) A. M.G. Cali et al. DIABETES CARE
- Impaired Hyperglycemia-Induced Delay in Gastric Emptying in Patients With Type 1 Diabetes Deficient for Islet Amyloid Polypeptide
- (2008) H. J. Woerle et al. DIABETES CARE
- Restoring a functional β-cell mass in diabetes
- (2008) D. Pipeleers et al. DIABETES OBESITY & METABOLISM
- Pancreatic β-cell mass in European subjects with type 2 diabetes
- (2008) J. Rahier et al. DIABETES OBESITY & METABOLISM
- Classical and model-based estimates of beta-cell function during a mixed meal vs. an OGTT in a population-based cohort
- (2008) Josina M. Rijkelijkhuizen et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Expression of the GLP-1 Receptor in Mouse, Rat, and Human Pancreas
- (2008) Ditte Tornehave et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- Relationship between pancreatic vesicular monoamine transporter 2 (VMAT2) and insulin expression in human pancreas
- (2008) Yoshifumi Saisho et al. JOURNAL OF MOLECULAR HISTOLOGY
- Concordance for Islet Autoimmunity among Monozygotic Twins
- (2008) Maria J. Redondo et al. NEW ENGLAND JOURNAL OF MEDICINE
- Genotype Score in Addition to Common Risk Factors for Prediction of Type 2 Diabetes
- (2008) James B. Meigs et al. NEW ENGLAND JOURNAL OF MEDICINE
- Clinical Risk Factors, DNA Variants, and the Development of Type 2 Diabetes
- (2008) Valeriya Lyssenko et al. NEW ENGLAND JOURNAL OF MEDICINE
- Extent of Beta Cell Destruction Is Important but Insufficient to Predict the Onset of Type 1 Diabetes Mellitus
- (2008) David J. Klinke PLoS One
- Pancreatic scintigraphy with 99mTc-interleukin-2 at diagnosis of type 1 diabetes and after 1 year of nicotinamide therapy
- (2007) M. Chianelli et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started