Interleukin-1 antagonism moderates the inflammatory state associated with Type 1 diabetes during clinical trials conducted at disease onset

Molecular Signatures Differentiate Immune States in Type 1 Diabetic Families

(2014) Yi-Guang Chen et al.   DIABETES

Combination Therapy With an Anti–IL-1β Antibody and GAD65 DNA Vaccine Can Reverse Recent-Onset Diabetes in the RIP-GP Mouse Model

(2014) Philippe P. Pagni et al.   DIABETES

Identification of a Molecular Signature in Human Type 1 Diabetes Mellitus Using Serum and Functional Genomics

(2014) X. Wang et al.   JOURNAL OF IMMUNOLOGY

Impaired Resolution of Inflammation in theEndoglinHeterozygous Mouse Model of Chronic Colitis

(2014) Madonna R. Peter et al.   MEDIATORS OF INFLAMMATION

Modulation of virus-induced innate immunity and type 1 diabetes by IL-1 blockade

(2013) Naoko Hara et al.   Innate Immunity

Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled trials

(2013) Antoinette Moran et al.   LANCET

Fall in C-Peptide During First 2 Years From Diagnosis: Evidence of at Least Two Distinct Phases From Composite Type 1 Diabetes TrialNet Data

(2012) C. J. Greenbaum et al.   DIABETES

Effects of Gevokizumab on Glycemia and Inflammatory Markers in Type 2 Diabetes

(2012) C. Cavelti-Weder et al.   DIABETES CARE

Transcriptional signatures as a disease-specific and predictive inflammatory biomarker for type 1 diabetes

(2012) H Levy et al.   GENES AND IMMUNITY

Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases

(2012) Charles A. Dinarello et al.   NATURE REVIEWS DRUG DISCOVERY

Synergistic Reversal of Type 1 Diabetes in NOD Mice With Anti-CD3 and Interleukin-1 Blockade: Evidence of Improved Immune Regulation

(2011) V. Ablamunits et al.   DIABETES

Teplizumab for treatment of type 1 diabetes (Protégé study): 1-year results from a randomised, placebo-controlled trial

(2011) Nicole Sherry et al.   LANCET

Identification of a Serum-Induced Transcriptional Signature Associated With Type 1 Diabetes in the BioBreeding Rat

(2010) M. Kaldunski et al.   DIABETES

Etiology of Type 1 Diabetes

(2010) John A. Todd   IMMUNITY

Staphylococcus aureus Stimulates Neutrophil Targeting Chemokine Expression in Keratinocytes through an Autocrine IL-1α Signaling Loop

(2010) Florina Olaru et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Blockade of interleukin 1 in type 1 diabetes mellitus

(2010) Thomas Mandrup-Poulsen et al.   Nature Reviews Endocrinology

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function

(2009) Mark D. Pescovitz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cell surface-bound IL-1  is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network

(2009) A. V. Orjalo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA