Western diet as a trigger of Alzheimer’s disease: From metabolic syndrome and systemic inflammation to neuroinflammation and neurodegeneration

Unhealthy foods may attenuate the beneficial relation of a Mediterranean diet to cognitive decline

(2021) Puja Agarwal et al.   Alzheimers & Dementia

Agomelatine effects on fat-enriched diet induced neuroinflammation and depression-like behavior in rats

(2021) Redouane Rebai et al.   BIOMEDICINE & PHARMACOTHERAPY

The Neuroinflammatory and Neurotoxic Potential of Palmitic Acid Is Mitigated by Oleic Acid in Microglial Cells and Microglial-Neuronal Co-cultures

(2021) Jimmy Beaulieu et al.   MOLECULAR NEUROBIOLOGY

Genome-wide meta-analysis, fine-mapping and integrative prioritization implicate new Alzheimer’s disease risk genes

(2021) Jeremy Schwartzentruber et al.   NATURE GENETICS

Western Diet Induces Impairment of Liver-Brain Axis Accelerating Neuroinflammation and Amyloid Pathology in Alzheimer's Disease

(2021) Angelika Wiȩckowska-Gacek et al.   Frontiers in Aging Neuroscience

Gut microbial taxa elevated by dietary sugar disrupt memory function

(2021) Emily E. Noble et al.   Translational Psychiatry

Inflammatory pathways in Alzheimer’s disease mediated by gut microbiota

(2021) Xiao-hang Qian et al.   AGEING RESEARCH REVIEWS

Late-life obesity is a protective factor for prodromal Alzheimer’s disease: a longitudinal study

(2020) Zhen Sun et al.   Aging-US

Midlife Modifiable Risk Factors for Dementia: A Systematic Review and Meta-analysis of 34 Prospective Cohort Studies

(2020) Xiao-Ying Li et al.   Current Alzheimer Research

Dystrophic microglia in late‐onset Alzheimer's disease

(2020) Wolfgang J. Streit et al.   GLIA

What Are the Molecular Mechanisms by Which Functional Bacterial Amyloids Influence Amyloid Beta Deposition and Neuroinflammation in Neurodegenerative Disorders?

(2020) Robert P. Friedland et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Lipopolysaccharide induces neuroinflammation in microglia by activating the MTOR pathway and downregulating Vps34 to inhibit autophagosome formation

(2020) Xiaoxia Ye et al.   Journal of Neuroinflammation

Interpretation of risk loci from genome-wide association studies of Alzheimer's disease

(2020) Shea J Andrews et al.   LANCET NEUROLOGY

Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain

(2020) Julia Marschallinger et al.   NATURE NEUROSCIENCE

Glymphatic System Impairment in Alzheimer’s Disease and Idiopathic Normal Pressure Hydrocephalus

(2020) Benjamin C. Reeves et al.   TRENDS IN MOLECULAR MEDICINE

Chronic Adipose Tissue Inflammation Linking Obesity to Insulin Resistance and Type 2 Diabetes

(2020) Federica Zatterale et al.   Frontiers in Physiology

The Impact of Dietary Components on Regulatory T Cells and Disease

(2020) Rebeca Arroyo Hornero et al.   Frontiers in Immunology

Hippocampal-dependent appetitive control is impaired by experimental exposure to a Western-style diet

(2020) Richard J. Stevenson et al.   Royal Society Open Science

Amyloid β-protein and beyond: the path forward in Alzheimer’s disease

(2020) Dominic M Walsh et al.   CURRENT OPINION IN NEUROBIOLOGY

Obesity and Alzheimer’s disease: Molecular bases

(2020) Pasquale Picone et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Is Alzheimer’s Disease a Liver Disease of the Brain?

(2020) Margaret F. Bassendine et al.   JOURNAL OF ALZHEIMERS DISEASE

The blood–brain barrier in health and disease: Important unanswered questions

(2020) Caterina P. Profaci et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lipopolysaccharide activates microglia via neuraminidase 1 desialylation of Toll‐like Receptor 4

(2020) David Hans Allendorf et al.   JOURNAL OF NEUROCHEMISTRY

Maternal high-fat diet induces sex-specific changes to glucocorticoid and inflammatory signaling in response to corticosterone and lipopolysaccharide challenge in adult rat offspring

(2020) Sanoji Wijenayake et al.   Journal of Neuroinflammation

A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease

(2020) Nicolas R. Barthélemy et al.   NATURE MEDICINE

Influence of Western diet and APOE genotype on Alzheimer's disease risk

(2020) P.M. Sullivan   NEUROBIOLOGY OF DISEASE

Alzheimer’s Risk Factors Age, APOE Genotype, and Sex Drive Distinct Molecular Pathways

(2020) Na Zhao et al.   NEURON

Metabolic Reprograming of Microglia in the Regulation of the Innate Inflammatory Response

(2020) Clotilde Lauro et al.   Frontiers in Immunology

Peripheral clearance of brain-derived Aβ in Alzheimer's disease: pathophysiology and therapeutic perspectives

(2020) Yuan Cheng et al.   Translational Neurodegeneration

Targeting and Crossing the Blood-Brain Barrier with Extracellular Vesicles

(2020) Julien Saint-Pol et al.   Cells

Healthy Brain, Healthy Life: a review of diet and exercise interventions to promote brain health and reduce Alzheimer’s disease risk

(2020) Bradley J. Baranowski et al.   Applied Physiology Nutrition and Metabolism

Diet, inflammation and the gut microbiome: Mechanisms for obesity-associated cognitive impairment

(2020) Sarah-Jane Leigh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Early diagnosis of Alzheimer’s disease: the role of biomarkers including advanced EEG signal analysis. Report from the IFCN-sponsored panel of experts

(2020) P.M. Rossini et al.   CLINICAL NEUROPHYSIOLOGY

25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner

(2020) Man Ying Wong et al.   Journal of Neuroinflammation

Dementia prevention, intervention, and care: 2020 report of the Lancet Commission

(2020) Gill Livingston et al.   LANCET

Brain insulin resistance in Alzheimer's disease and related disorders: mechanisms and therapeutic approaches

(2020) Derek Kellar et al.   LANCET NEUROLOGY

Short-chain fatty acids (SCFAs) alone or in combination regulate select immune functions of microglia-like cells

(2020) Tyler J. Wenzel et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

A Short‐Term Western Diet Impairs Cholesterol Homeostasis and Key Players of Beta Amyloid Metabolism in Brain of Middle Aged Rats

(2020) Maria Stefania Spagnuolo et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Metabolic Inflammation in Obesity – At the Crossroads Between Fatty Acid and Cholesterol Metabolism

(2020) Sean Curley et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Synergy between amyloid-β and tau in Alzheimer’s disease

(2020) Marc Aurel Busche et al.   NATURE NEUROSCIENCE

The age-related microglial transformation in Alzheimer's disease pathogenesis

(2020) Chunxu Yuan et al.   NEUROBIOLOGY OF AGING

New mechanism of neuroinflammation in Alzheimer's disease: The activation of NLRP3 inflammasome mediated by gut microbiota

(2020) Heping Shen et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

APOE Alleles and Diet in Brain Aging and Alzheimer’s Disease

(2020) Hussein N. Yassine et al.   Frontiers in Aging Neuroscience

High-fat diet-induced adipose tissue and liver inflammation and steatosis in mice are reduced by inhibiting sialidases

(2020) Darrell Pilling et al.   AMERICAN JOURNAL OF PATHOLOGY

Lychee seed polyphenol inhibits Aβ-induced activation of NLRP3 inflammasome via the LRP1/AMPK mediated autophagy induction

(2020) Wen-Qiao Qiu et al.   BIOMEDICINE & PHARMACOTHERAPY

Shifting paradigms: The central role of microglia in Alzheimer's disease

(2020) Tina Schwabe et al.   NEUROBIOLOGY OF DISEASE

Lifestyle intervention to prevent Alzheimer’s disease

(2020) Yi Ko et al.   REVIEWS IN THE NEUROSCIENCES

Metabolic Defects Caused by High-Fat Diet Modify Disease Risk through Inflammatory and Amyloidogenic Pathways in a Mouse Model of Alzheimer’s Disease

(2020) Austin M. Reilly et al.   Nutrients

Microglia prevent beta-amyloid plaque formation in the early stage of an Alzheimer’s disease mouse model with suppression of glymphatic clearance

(2020) Weixi Feng et al.   Alzheimers Research & Therapy

Germ‐free mice are not protected against diet‐induced obesity and metabolic dysfunction

(2020) Chiara H. Moretti et al.   Acta Physiologica

Targeting microglial autophagic degradation in NLRP3 inflammasome-mediated neurodegenerative diseases

(2020) An-Guo Wu et al.   AGEING RESEARCH REVIEWS

Adipose Tissue Inflammation and Metabolic Dysfunction in Obesity

(2020) Tatsuo Kawai et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Sulfated polysaccharides from Undaria pinnatifida improved high fat diet-induced metabolic syndrome, gut microbiota dysbiosis and inflammation in BALB/c mice

(2020) Pingrui Jiang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Comprehensive Review on Alzheimer’s Disease: Causes and Treatment

(2020) Zeinab Breijyeh et al.   MOLECULES

The Effect of Short-Term Feeding of a High-Coconut Oil or High-Fat Diet on Neuroinflammation and the Performance of an Object–Place Task in Rats

(2020) Badrah Saeed Alghamdi   NEUROCHEMICAL RESEARCH

Gut microbiota in dementia. Critical review of novel findings and their potential application

(2020) Mateusz Łuc et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Inflammation initiates a vicious cycle between obesity and nonalcoholic fatty liver disease

(2020) Yunfei Luo et al.   Immunity Inflammation and Disease

Tinospora cordifolia ameliorates brain functions impairments associated with high fat diet induced obesity

(2020) Harpal Singh et al.   NEUROCHEMISTRY INTERNATIONAL

A Multilevel View of the Development of Alzheimer’s Disease

(2020) Jesús Avila et al.   NEUROSCIENCE

The impact of the microbiota-gut-brain axis on Alzheimer’s disease pathophysiology

(2020) Tejaswini Doifode et al.   PHARMACOLOGICAL RESEARCH

Vascular dysfunction—The disregarded partner of Alzheimer's disease

(2019) Melanie D. Sweeney et al.   Alzheimers & Dementia

Lipopolysaccharide-induced alteration of mitochondrial morphology induces a metabolic shift in microglia modulating the inflammatory response in vitro and in vivo

(2019) Syam Nair et al.   GLIA

Brain-Gut-Microbiota Axis in Alzheimer’s Disease

(2019) Karol Kowalski et al.   Journal of Neurogastroenterology and Motility

Neurochemical Modifications in the Hippocampus, Cortex and Hypothalamus of Mice Exposed to Long-Term High-Fat Diet

(2019) Blanca Lizarbe et al.   Frontiers in Neuroscience

Aquaporin-4 Water Channel in the Brain and Its Implication for Health and Disease

(2019) Simone Mader et al.   Cells

Activation of microglia and astrocytes: a roadway to neuroinflammation and Alzheimer’s disease

(2019) Darshpreet Kaur et al.   INFLAMMOPHARMACOLOGY

Effect of the HDAC Inhibitor, Sodium Butyrate, on Neurogenesis in a Rat Model of Neonatal Hypoxia–Ischemia: Potential Mechanism of Action

(2019) Joanna Jaworska et al.   MOLECULAR NEUROBIOLOGY

Role of cholesterol and sphingolipids in brain development and neurological diseases

(2019) Ghulam Hussain et al.   Lipids in Health and Disease

Alterations in cholesterol metabolism as a risk factor for developing Alzheimer's disease: Potential novel targets for treatment

(2019) Raúl Loera-Valencia et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

The Role of Gut Microbiota in Pathogenesis of Alzheimer's Disease

(2019) Mehmet Bostanciklioğlu   JOURNAL OF APPLIED MICROBIOLOGY

The role of DNA methylation and hydroxymethylation in immunosenescence

(2019) Nicholas D. Johnson et al.   AGEING RESEARCH REVIEWS

Brain serotonin in high-fat diet-induced weight gain, anxiety and spatial memory in rats

(2019) Darakhshan Jabeen Haleem et al.   NUTRITIONAL NEUROSCIENCE

NLRP3 inflammasome inhibition with MCC950 improves diabetes-mediated cognitive impairment and vasoneuronal remodeling after ischemia

(2019) Rebecca Ward et al.   PHARMACOLOGICAL RESEARCH

Saturated fatty acids induce NLRP3 activation in human macrophages through K+ efflux resulting from phospholipid saturation and Na, K-ATPase disruption

(2019) Marco A. Gianfrancesco et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The effect of palmitic acid on inflammatory response in macrophages: an overview of molecular mechanisms

(2019) Jan Korbecki et al.   INFLAMMATION RESEARCH

Ciprofloxacin and levofloxacin attenuate microglia inflammatory response via TLR4/NF-kB pathway

(2019) Morena Zusso et al.   Journal of Neuroinflammation

Deciphering the Role of WNT Signaling in Metabolic Syndrome–Linked Alzheimer’s Disease

(2019) Abuzer Ali et al.   MOLECULAR NEUROBIOLOGY

Protective effect of Curcuma amada acetone extract against high-fat and high-sugar diet-induced obesity and memory impairment

(2019) Lakshmi Sudeepthi Nissankara Rao et al.   NUTRITIONAL NEUROSCIENCE

Liver Dysfunction as a Novel Player in Alzheimer’s Progression: Looking Outside the Brain

(2019) Lisbell D. Estrada et al.   Frontiers in Aging Neuroscience

Habitual sugar intake and cognitive impairment among multi-ethnic Malaysian older adults

(2019) C.P. Chong et al.   Clinical Interventions in Aging

Intersection of pathological tau and microglia at the synapse

(2019) Thomas Vogels et al.   Acta Neuropathologica Communications

Non-Alcoholic Fatty Liver Disease, and the Underlying Altered Fatty Acid Metabolism, Reveals Brain Hypoperfusion and Contributes to the Cognitive Decline in APP/PS1 Mice

(2019) Anthony Pinçon et al.   Metabolites

Apolipoprotein E gene polymorphism and the risk of cardiovascular disease and type 2 diabetes

(2019) Sudong Liu et al.   BMC Cardiovascular Disorders

The gut microbiome and metabolic syndrome

(2019) Kruttika Dabke et al.   JOURNAL OF CLINICAL INVESTIGATION

Amyloid-beta impairs insulin signaling by accelerating autophagy-lysosomal degradation of LRP-1 and IR-β in blood-brain barrier endothelial cells in vitro and in 3XTg-AD mice

(2019) Chaitanya Chakravarthi Gali et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

The neuroprotective role of microglial cells against amyloid beta‐mediated toxicity in organotypic hippocampal slice cultures

(2019) Maren Richter et al.   BRAIN PATHOLOGY

Western Diet and the Immune System: An Inflammatory Connection

(2019) Anette Christ et al.   IMMUNITY

Green Tea Polyphenol (−)-Epigallocatechin Gallate (EGCG) Attenuates Neuroinflammation in Palmitic Acid-Stimulated BV-2 Microglia and High-Fat Diet-Induced Obese Mice

(2019) Limin Mao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Blood–Brain Barrier and Its Intercellular Junctions in Age-Related Brain Disorders

(2019) Laura Costea et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Transcriptome profiling of brain myeloid cells revealed activation of Itgal, Trem1, and Spp1 in western diet-induced obesity

(2019) Hongtian Yang et al.   Journal of Neuroinflammation

The endotoxin hypothesis of neurodegeneration

(2019) Guy C. Brown   Journal of Neuroinflammation

A high-sucrose diet aggravates Alzheimer's disease pathology, attenuates hypothalamic leptin signaling, and impairs food-anticipatory activity in APPswe/PS1dE9 mice

(2019) Skye Hsin-Hsien Yeh et al.   NEUROBIOLOGY OF AGING

Role of Microglial Cells in Alzheimer’s Disease Tau Propagation

(2019) Ena Španić et al.   Frontiers in Aging Neuroscience

Metabolically healthy obesity reduces the risk of Alzheimer’s disease in elders: a longitudinal study

(2019) Ling-Zhi Ma et al.   Aging-US

Endothelial Cell Calcium Signaling during Barrier Function and Inflammation

(2019) Prarthana J. Dalal et al.   AMERICAN JOURNAL OF PATHOLOGY

mTOR‐mediated metabolic reprogramming shapes distinct microglia functions in response to lipopolysaccharide and ATP

(2019) Yaling Hu et al.   GLIA

Vascular Risk Factors and Alzheimer’s Disease: Blood-Brain Barrier Disruption, Metabolic Syndromes, and Molecular Links

(2019) Jin-Ting He et al.   JOURNAL OF ALZHEIMERS DISEASE

LIPID RAFTS AND NEURODEGENERATION: Structural and functional roles in physiologic aging and neurodegenerative diseases

(2019) Sara Grassi et al.   JOURNAL OF LIPID RESEARCH

Linking APOE-ε4, blood-brain barrier dysfunction, and inflammation to Alzheimer's pathology

(2019) Joost M. Riphagen et al.   NEUROBIOLOGY OF AGING

Aging and Alzheimer's disease pathology

(2019) Renpei Sengoku   NEUROPATHOLOGY

The effect of high fat, high sugar, and combined high fat-high sugar diets on spatial learning and memory in rodents: A meta-analysis

(2019) Kirsten N. Abbott et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Functional morphology of the blood–brain barrier in health and disease

(2018) Stefan Liebner et al.   ACTA NEUROPATHOLOGICA

The role of aquaporin-4 in synaptic plasticity, memory and disease

(2018) Jacqueline A. Hubbard et al.   BRAIN RESEARCH BULLETIN

Sustained high-fat diet modulates inflammation, insulin signalling and cognition in mice and a modified xenin peptide ameliorates neuropathology in a chronic high-fat model

(2018) Paul Denver et al.   DIABETES OBESITY & METABOLISM

Dysregulated bile acid synthesis and dysbiosis are implicated in Western diet–induced systemic inflammation, microglial activation, and reduced neuroplasticity

(2018) Prasant Kumar Jena et al.   FASEB JOURNAL

Human Gut Microbiota in Health and Alzheimer’s Disease

(2018) Leszek Szablewski   JOURNAL OF ALZHEIMERS DISEASE

Increased Prevalence of Obesity/Type 2 Diabetes and Lower Levels of Lithium in Rural Texas Counties May Explain Greater Alzheimer’s Disease Risk

(2018) Bradley J. Baranowski et al.   JOURNAL OF ALZHEIMERS DISEASE

Role of Blood-Brain Barrier in Alzheimer’s Disease

(2018) Zhiyou Cai et al.   JOURNAL OF ALZHEIMERS DISEASE

Gut Microbiota is Altered in Patients with Alzheimer’s Disease

(2018) Zhen-Qian Zhuang et al.   JOURNAL OF ALZHEIMERS DISEASE

Cognitive impairment in metabolically-obese, normal-weight rats: identification of early biomarkers in peripheral blood mononuclear cells

(2018) Margalida Cifre et al.   Molecular Neurodegeneration

Increased Levels of 27-Hydroxycholesterol Induced by Dietary Cholesterol in Brain Contribute to Learning and Memory Impairment in Rats

(2018) Xiaona Zhang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Mechanisms of NAFLD development and therapeutic strategies

(2018) Scott L. Friedman et al.   NATURE MEDICINE

Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders

(2018) Melanie D. Sweeney et al.   Nature Reviews Neurology

“Lipid raft aging” in the human frontal cortex during nonpathological aging: gender influences and potential implications in Alzheimer's disease

(2018) Mario Díaz et al.   NEUROBIOLOGY OF AGING

Oxidant/Antioxidant Imbalance in Alzheimer’s Disease: Therapeutic and Diagnostic Prospects

(2018) Joanna Wojsiat et al.   Oxidative Medicine and Cellular Longevity

Diet, gut microbiota composition and feeding behavior

(2018) Jiyoung S. Kim et al.   PHYSIOLOGY & BEHAVIOR

Reduced cognitive function, increased blood-brain-barrier transport and inflammatory responses, and altered brain metabolites in LDLr -/-and C57BL/6 mice fed a western diet

(2018) Jennifer M. Rutkowsky et al.   PLoS One

Comparing Effects of Transforming Growth Factor β1 on Microglia From Rat and Mouse: Transcriptional Profiles and Potassium Channels

(2018) Starlee Lively et al.   Frontiers in Cellular Neuroscience

Interrelation of Diet, Gut Microbiome, and Autoantibody Production

(2018) Ioanna Petta et al.   Frontiers in Immunology

Immunosenescence and Inflamm-Aging As Two Sides of the Same Coin: Friends or Foes?

(2018) Tamas Fulop et al.   Frontiers in Immunology

High salt diet exacerbates colitis in mice by decreasing Lactobacillus levels and butyrate production

(2018) Pedro M. Miranda et al.   Microbiome

Microbiota modulation by eating patterns, dietary and macronutrient composition; impact on food intake

(2018) Elizabeth A. Klingbeil et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Alzheimer's disease and Type 2 Diabetes mellitus are distinct diseases with potential overlapping metabolic dysfunction upstream of observed cognitive decline

(2018) Yevgen Chornenkyy et al.   BRAIN PATHOLOGY

Loss of Astrocyte Polarization in the Tg-ArcSwe Mouse Model of Alzheimer's Disease

(2018) Jing Yang et al.   JOURNAL OF ALZHEIMERS DISEASE

Diabetes and Hypercholesterolemia Increase Blood-Brain Barrier Permeability and Brain Amyloid Deposition: Beneficial Effects of the LpPLA2 Inhibitor Darapladib

(2018) Nimish K. Acharya et al.   JOURNAL OF ALZHEIMERS DISEASE

Microglial signatures and their role in health and disease

(2018) Oleg Butovsky et al.   NATURE REVIEWS NEUROSCIENCE

Relevance of gutmicrobiota in cognition, behaviour and Alzheimer’s disease

(2018) Vanessa de J.R. De-Paula et al.   PHARMACOLOGICAL RESEARCH

Non-Alcoholic Fatty Liver Disease in Overweight Children: Role of Fructose Intake and Dietary Pattern

(2018) Anika Nier et al.   Nutrients

Rapid and reversible impairment of episodic memory by a high-fat diet in mice

(2018) Fiona H. McLean et al.   Scientific Reports

Diet induced obesity is independent of metabolic endotoxemia and TLR4 signalling, but markedly increases hypothalamic expression of the acute phase protein, SerpinA3N

(2018) Matthew J. Dalby et al.   Scientific Reports

Butyrate and Dietary Soluble Fiber Improve Neuroinflammation Associated With Aging in Mice

(2018) Stephanie M. Matt et al.   Frontiers in Immunology

Gut Microbiome in Obesity, Metabolic Syndrome, and Diabetes

(2018) Xinpu Chen et al.   Current Diabetes Reports

CD11a expression distinguishes infiltrating myeloid cells from plaque-associated microglia in Alzheimer's disease

(2018) Ankita K. Shukla et al.   GLIA

TLR4 inhibitor TAK-242 attenuates the adverse neural effects of diet-induced obesity

(2018) V. Alexandra Moser et al.   Journal of Neuroinflammation

On the fluxes of side-chain oxidized oxysterols across blood-brain and blood-CSF barriers and origin of these steroids in CSF (Review)

(2018) Ingemar Björkhem et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

The glymphatic pathway in neurological disorders

(2018) Martin Kaag Rasmussen et al.   LANCET NEUROLOGY

Dynamics and functions of lipid droplets

(2018) James A. Olzmann et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lifestyle interventions to prevent cognitive impairment, dementia and Alzheimer disease

(2018) Miia Kivipelto et al.   Nature Reviews Neurology

Blood-Brain Barrier: From Physiology to Disease and Back

(2018) Melanie D. Sweeney et al.   PHYSIOLOGICAL REVIEWS

The integration of inflammaging in age-related diseases

(2018) Tamas Fulop et al.   SEMINARS IN IMMUNOLOGY

Gut Microbiota and Their Neuroinflammatory Implications in Alzheimer’s Disease

(2018) Vo Giau et al.   Nutrients

Impact of Metabolic Syndrome on Neuroinflammation and the Blood–Brain Barrier

(2018) Peter Van Dyken et al.   Frontiers in Neuroscience

Rusty Microglia: Trainers of Innate Immunity in Alzheimer's Disease

(2018) Adonis Sfera et al.   Frontiers in Neurology

High-fat diet worsens the impact of aging on microglial function and morphology in a region-specific manner

(2018) Sarah J. Spencer et al.   NEUROBIOLOGY OF AGING

Sex differences in the phagocytic and migratory activity of microglia and their impairment by palmitic acid

(2017) Natalia Yanguas-Casás et al.   GLIA

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

(2017) Susanne Krasemann et al.   IMMUNITY

Autophagy and Microglia: Novel Partners in Neurodegeneration and Aging

(2017) Ainhoa Plaza-Zabala et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Blood-Brain Barrier Dysfunction and the Pathogenesis of Alzheimer’s Disease

(2017) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Gut Microbiota and Alzheimer’s Disease

(2017) Chunmei Jiang et al.   JOURNAL OF ALZHEIMERS DISEASE

Interaction of amyloid-β (Aβ) oligomers with neurexin 2α and neuroligin 1 mediates synapse damage and memory loss in mice

(2017) Jordano Brito-Moreira et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Western diet induces colonic nitrergic myenteric neuropathy and dysmotility in mice via saturated fatty acid- and lipopolysaccharide-induced TLR4 signalling

(2017) François Reichardt et al.   JOURNAL OF PHYSIOLOGY-LONDON

Long-term Impact of Weight Loss Intervention on Changes in Cognitive Function: Exploratory Analyses from the Action for Health in Diabetes Randomized Controlled Clinical Trial

(2017) Mark A Espeland et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Dementia prevention, intervention, and care

(2017) Gill Livingston et al.   LANCET

Pioglitazone ameliorates Aβ42 deposition in rats with diet-induced insulin resistance associated with AKT/GSK3β activation

(2017) Sisi Yang et al.   Molecular Medicine Reports

Inflammation, metaflammation and immunometabolic disorders

(2017) Gökhan S. Hotamisligil   NATURE

Microglia emerge as central players in brain disease

(2017) Michael W Salter et al.   NATURE MEDICINE

Suche nach Risikogenen bei der Alzheimer-Erkrankung

(2017) I. Karaca et al.   NERVENARZT

Cholesterol-metabolizing enzyme cytochrome P450 46A1 as a pharmacologic target for Alzheimer's disease

(2017) Natalia Mast et al.   NEUROPHARMACOLOGY

A four-day Western-style dietary intervention causes reductions in hippocampal-dependent learning and memory and interoceptive sensitivity

(2017) Tuki Attuquayefio et al.   PLoS One

The relationship between obesity and cognitive health and decline

(2017) Louise Dye et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

The hippocampus and the regulation of human food intake.

(2017) Richard J. Stevenson et al.   PSYCHOLOGICAL BULLETIN

Alzheimer's disease and metabolic syndrome: A link from oxidative stress and inflammation to neurodegeneration

(2017) Eduardo Rojas-Gutierrez et al.   SYNAPSE

The blood brain barrier in Alzheimer’s disease

(2017) A. Chakraborty et al.   VASCULAR PHARMACOLOGY

On the path to 2025: understanding the Alzheimer’s disease continuum

(2017) Paul S. Aisen et al.   Alzheimers Research & Therapy

The role of microbial amyloid in neurodegeneration

(2017) Robert P. Friedland et al.   PLoS Pathogens

Association of Perivascular Localization of Aquaporin-4 With Cognition and Alzheimer Disease in Aging Brains

(2017) Douglas M. Zeppenfeld et al.   JAMA Neurology

Intermittent Fasting Protects against Alzheimer’s Disease Possible through Restoring Aquaporin-4 Polarity

(2017) Jingzhu Zhang et al.   Frontiers in Molecular Neuroscience

T Lymphocytes and Inflammatory Mediators in the Interplay between Brain and Blood in Alzheimer’s Disease: Potential Pools of New Biomarkers

(2017) Anna Mietelska-Porowska et al.   Journal of Immunology Research

The Effects of a High-Energy Diet on Hippocampal Function and Blood-Brain Barrier Integrity in the Rat

(2017) Scott E. Kanoski et al.   JOURNAL OF ALZHEIMERS DISEASE

Effect of high fat diet on phenotype, brain transcriptome and lipidome in Alzheimer’s model mice

(2017) Kyong Nyon Nam et al.   Scientific Reports

Gut microbiome alterations in Alzheimer’s disease

(2017) Nicholas M. Vogt et al.   Scientific Reports

Impact of enriched environment on production of tau, amyloid precursor protein and, amyloid-β peptide in high-fat and high-sucrose-fed rats

(2016) Yavuz Selvi et al.   ACTA NEUROPSYCHIATRICA

The risk of overweight/obesity in mid-life and late life for the development of dementia: a systematic review and meta-analysis of longitudinal studies

(2016) Emilio Pedditizi et al.   AGE AND AGEING

Distinct inflammatory phenotypes of microglia and monocyte-derived macrophages in Alzheimer's disease models: effects of aging and amyloid pathology

(2016) Elodie Martin et al.   AGING CELL

Apolipoprotein E4 association with metabolic syndrome depends on body fatness

(2016) Elena Torres-Perez et al.   ATHEROSCLEROSIS

Saturated fatty acids trigger TLR4-mediated inflammatory response

(2016) D.M. Rocha et al.   ATHEROSCLEROSIS

Western diets induce blood-brain barrier leakage and alter spatial strategies in rats.

(2016) Sara L. Hargrave et al.   BEHAVIORAL NEUROSCIENCE

Short-term exposure to a diet high in fat and sugar, or liquid sugar, selectively impairs hippocampal-dependent memory, with differential impacts on inflammation

(2016) J.E. Beilharz et al.   BEHAVIOURAL BRAIN RESEARCH

Neurovascular dysfunction and neurodegeneration in dementia and Alzheimer's disease

(2016) Amy R. Nelson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Membrane raft domains and remodeling in aging brain

(2016) Julie Colin et al.   BIOCHIMIE

Imbalanced cholesterol metabolism in Alzheimer's disease

(2016) Zhao Xue-shan et al.   CLINICA CHIMICA ACTA

Differential Kv1.3, KCa3.1, and Kir2.1 expression in “classically” and “alternatively” activated microglia

(2016) Hai M. Nguyen et al.   GLIA

Communicating systems in the body: how microbiota and microglia cooperate

(2016) Daniel Erny et al.   IMMUNOLOGY

High-fat diet feeding differentially affects the development of inflammation in the central nervous system

(2016) Owein Guillemot-Legris et al.   Journal of Neuroinflammation

Non-alcoholic fatty liver disease induces signs of Alzheimer’s disease (AD) in wild-type mice and accelerates pathological signs of AD in an AD model

(2016) Do-Geun Kim et al.   Journal of Neuroinflammation

Astrocyte-Microglia Cross Talk through Complement Activation Modulates Amyloid Pathology in Mouse Models of Alzheimer's Disease

(2016) H. Lian et al.   JOURNAL OF NEUROSCIENCE

Mango Supplementation Modulates Gut Microbial Dysbiosis and Short-Chain Fatty Acid Production Independent of Body Weight Reduction in C57BL/6 Mice Fed a High-Fat Diet

(2016) Babajide Ojo et al.   JOURNAL OF NUTRITION

Associations Between Hepatic Functions and Plasma Amyloid-Beta Levels—Implications for the Capacity of Liver in Peripheral Amyloid-Beta Clearance

(2016) Ye-Ran Wang et al.   MOLECULAR NEUROBIOLOGY

Diet–microbiota interactions as moderators of human metabolism

(2016) Justin L. Sonnenburg et al.   NATURE

Suppression of glymphatic fluid transport in a mouse model of Alzheimer's disease

(2016) Weiguo Peng et al.   NEUROBIOLOGY OF DISEASE

Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer’s disease

(2016) Leah C. Graham et al.   Scientific Reports

Human gut microbiota: the links with dementia development

(2016) Rashad Alkasir et al.   Protein & Cell

Impact of enriched environment on production of tau, amyloid precursor protein and, amyloid-β peptide in high-fat and high-sucrose-fed rats

(2016) Yavuz Selvi et al.   ACTA NEUROPSYCHIATRICA

Impact of Dietary Lipids on Colonic Function and Microbiota: An Experimental Approach Involving Orlistat-Induced Fat Malabsorption in Human Volunteers

(2016) Pamela Morales et al.   Clinical and Translational Gastroenterology

Sexually dimorphic brain fatty acid composition in low and high fat diet-fed mice

(2016) Carlos Rodriguez-Navas et al.   Molecular Metabolism

Changes in brain oxysterols at different stages of Alzheimer's disease: Their involvement in neuroinflammation

(2016) Gabriella Testa et al.   Redox Biology

Adipose Tissue Remodeling: Its Role in Energy Metabolism and Metabolic Disorders

(2016) Sung Sik Choe et al.   Frontiers in Endocrinology

27-Hydroxycholesterol mediates negative effects of dietary cholesterol on cognition in mice

(2015) Maura Heverin et al.   BEHAVIOURAL BRAIN RESEARCH

Fructose consumption reduces hippocampal synaptic plasticity underlying cognitive performance

(2015) Pedro Cisternas et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Obese-type Gut Microbiota Induce Neurobehavioral Changes in the Absence of Obesity

(2015) Annadora J. Bruce-Keller et al.   BIOLOGICAL PSYCHIATRY

Western diet is associated with a smaller hippocampus: a longitudinal investigation

(2015) Felice N. Jacka et al.   BMC Medicine

Microglial M1/M2 polarization and metabolic states

(2015) Ruben Orihuela et al.   BRITISH JOURNAL OF PHARMACOLOGY

Monounsaturated Fatty Acid–Enriched High-Fat Diets Impede Adipose NLRP3 Inflammasome–Mediated IL-1β Secretion and Insulin Resistance Despite Obesity

(2015) Orla M. Finucane et al.   DIABETES

Cholesterol-induced astrocyte activation is associated with increased amyloid precursor protein expression and processing

(2015) Evangelina Avila-Muñoz et al.   GLIA

Prevalence of the Metabolic Syndrome in the United States, 2003-2012

(2015) Maria Aguilar et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Palmitoleate Reverses High Fat-induced Proinflammatory Macrophage Polarization via AMP-activated Protein Kinase (AMPK)

(2015) Kenny L. Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipopolysaccharide-induced blood-brain barrier disruption: roles of cyclooxygenase, oxidative stress, neuroinflammation, and elements of the neurovascular unit

(2015) William A. Banks et al.   Journal of Neuroinflammation

A high-sugar high-fat diet induced metabolic syndrome shows some symptoms of Alzheimer’s disease in rats

(2015) L. Niu et al.   Journal of Nutrition Health & Aging

Host microbiota constantly control maturation and function of microglia in the CNS

(2015) Daniel Erny et al.   NATURE NEUROSCIENCE

Age- and location-related changes in microglial function

(2015) Rodney M. Ritzel et al.   NEUROBIOLOGY OF AGING

The Glymphatic System: A Beginner’s Guide

(2015) Nadia Aalling Jessen et al.   NEUROCHEMICAL RESEARCH

Lipidomic Profiling of Liver Tissue from Obesity-Prone and Obesity-Resistant Mice Fed a High Fat Diet

(2015) Miso Nam et al.   Scientific Reports

Plaque-associated lipids in Alzheimer’s diseased brain tissue visualized by nonlinear microscopy

(2015) Juris Kiskis et al.   Scientific Reports

Cholesterol metabolism and homeostasis in the brain

(2015) Juan Zhang et al.   Protein & Cell

Neuroprotective Effects ofClostridium butyricumagainst Vascular Dementia in Mice via Metabolic Butyrate

(2015) Jiaming Liu et al.   Biomed Research International

Dietary lipids are differentially associated with hippocampal-dependent relational memory in prepubescent children

(2014) Carol L Baym et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Luteolin protects against high fat diet-induced cognitive deficits in obesity mice

(2014) Yi Liu et al.   BEHAVIOURAL BRAIN RESEARCH

High-fat diet consumption disrupts memory and primes elevations in hippocampal IL-1β, an effect that can be prevented with dietary reversal or IL-1 receptor antagonism

(2014) Julia L. Sobesky et al.   BRAIN BEHAVIOR AND IMMUNITY

Adipose Tissue Macrophages Promote Myelopoiesis and Monocytosis in Obesity

(2014) Prabhakara R. Nagareddy et al.   Cell Metabolism

The effects of diet-induced obesity on B cell function

(2014) S. R. Shaikh et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Role of cholesterol metabolism in the pathogenesis of Alzheimerʼs disease

(2014) Bernadette Allinquant et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Insulin Reverses the High-Fat Diet-Induced Increase in Brain A  and Improves Memory in an Animal Model of Alzheimer Disease

(2014) M. Vandal et al.   DIABETES

Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis

(2014) Nagendra Singh et al.   IMMUNITY

Cereal Byproducts Have Prebiotic Potential in Mice Fed a High-Fat Diet

(2014) Karin Berger et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Short-Term High-Fat-and-Fructose Feeding Produces Insulin Signaling Alterations Accompanied by Neurite and Synaptic Reduction and Astroglial Activation in the Rat Hippocampus

(2014) Erika Calvo-Ochoa et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Differential roles of microglia and monocytes in the inflamed central nervous system

(2014) Ryo Yamasaki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dietary intervention rescues maternal obesity induced behavior deficits and neuroinflammation in offspring

(2014) Silvia S Kang et al.   Journal of Neuroinflammation

Impairment of Glymphatic Pathway Function Promotes Tau Pathology after Traumatic Brain Injury

(2014) Jeffrey J. Iliff et al.   JOURNAL OF NEUROSCIENCE

High-fat diet increases tau expression in the brain of T2DM and AD mice independently of peripheral metabolic status

(2014) Mari Takalo et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Long-term Impact of Behavioral Weight Loss Intervention on Cognitive Function

(2014) M. A. Espeland et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Vascular pathology of 20-month-old hypercholesterolemia mice in comparison to triple-transgenic and APPSwDI Alzheimer's disease mouse models

(2014) Lindsay A. Hohsfield et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Sodium Butyrate Prevents Memory Impairment by Re-establishing BDNF and GDNF Expression in Experimental Pneumococcal Meningitis

(2014) Tatiana Barichello et al.   MOLECULAR NEUROBIOLOGY

Crosstalk between Adipocytes and Immune Cells in Adipose Tissue Inflammation and Metabolic Dysregulation in Obesity

(2014) Jin Young Huh et al.   MOLECULES AND CELLS

High-fat diet-induced memory impairment in triple-transgenic Alzheimer's disease (3xTgAD) mice is independent of changes in amyloid and tau pathology

(2014) Elysse M. Knight et al.   NEUROBIOLOGY OF AGING

Water influx into cerebrospinal fluid is significantly reduced in senile plaque bearing transgenic mice, supporting beta-amyloid clearance hypothesis of Alzheimer’s disease

(2014) Hironaka Igarashi et al.   NEUROLOGICAL RESEARCH

Working memory and reward association learning impairments in obesity

(2014) Géraldine Coppin et al.   NEUROPSYCHOLOGIA

Immunohistochemical analysis of tau phosphorylation and astroglial activation with enhanced leptin receptor expression in diet-induced obesity mouse hippocampus

(2014) Shunsuke Koga et al.   NEUROSCIENCE LETTERS

Expression of Aquaporin 4 and Breakdown of the Blood-Brain Barrier after Hypoglycemia-Induced Brain Edema in Rats

(2014) Jiangshan Deng et al.   PLoS One

Blood-brain barrier disruption: mechanistic links between Western diet consumption and dementia

(2014) Ted M. Hsu et al.   Frontiers in Aging Neuroscience

Systemic inflammation, blood-brain barrier vulnerability and cognitive/non-cognitive symptoms in Alzheimer disease: relevance to pathogenesis and therapy

(2014) Shuko Takeda et al.   Frontiers in Aging Neuroscience

The low-density lipoprotein receptor-related protein 1 and amyloid-β clearance in Alzheimer’s disease

(2014) Takahisa Kanekiyo et al.   Frontiers in Aging Neuroscience

Arterial Stiffness and β-Amyloid Progression in Nondemented Elderly Adults

(2014) Timothy M. Hughes et al.   JAMA Neurology

The longer-term impacts of Western diet on human cognition and the brain

(2013) Heather Francis et al.   APPETITE

Body Mass Index, Weight Change, and Clinical Progression in Mild Cognitive Impairment and Alzheimer Disease

(2013) Lilah M. Besser et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Short exposure to a diet rich in both fat and sugar or sugar alone impairs place, but not object recognition memory in rats

(2013) Jessica E. Beilharz et al.   BRAIN BEHAVIOR AND IMMUNITY

T-Cell Costimulation Protects Obesity-Induced Adipose Inflammation and Insulin Resistance

(2013) J. Zhong et al.   DIABETES

Habitual fat intake predicts memory function in younger women

(2013) E. Leigh Gibson et al.   Frontiers in Human Neuroscience

Western diet induces dysbiosis with increasedE coliin CEABAC10 mice,alters host barrier function favouring AIEC colonisation

(2013) Margarita Martinez-Medina et al.   GUT

Liver damage is not reversed during the lean period in diet-induced weight cycling in mice

(2013) Sandra Barbosa-da-Silva et al.   HEPATOLOGY RESEARCH

Hypercholesterolemia accelerates amyloid β-induced cognitive deficits

(2013) SUN HAENG PARK et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Involvement of interleukin-1β in the autophagic process of microglia: relevance to Alzheimer’s disease

(2013) Arnaud François et al.   Journal of Neuroinflammation

Is obesity a brain disease?

(2013) Gabi Shefer et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Toll-Like Receptor 4 Knockout Mice Are Protected against Endoplasmic Reticulum Stress Induced by a High-Fat Diet

(2013) Nicolas Pierre et al.   PLoS One

Sex-Specific Effects of High Fat Diet on Indices of Metabolic Syndrome in 3xTg-AD Mice: Implications for Alzheimer's Disease

(2013) Anna M. Barron et al.   PLoS One

Alzheimer's disease and the microbiome

(2013) Surjyadipta Bhattacharjee et al.   Frontiers in Cellular Neuroscience

Mechanisms of Obesity-Induced Inflammation and Insulin Resistance: Insights into the Emerging Role of Nutritional Strategies

(2013) Maeve A. McArdle et al.   Frontiers in Endocrinology

Role of the blood-brain barrier in the evolution of feeding and cognition

(2012) William A. Banks   Annals of the New York Academy of Sciences

Increased oxidized low-density lipoprotein causes blood-brain barrier disruption in early-onset preeclampsia through LOX-1

(2012) Malou P. H. Schreurs et al.   FASEB JOURNAL

Palmitate and Lipopolysaccharide Trigger Synergistic Ceramide Production in Primary Macrophages

(2012) Joel D. Schilling et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characteristics of Aquaporin Expression Surrounding Senile Plaques and Cerebral Amyloid Angiopathy in Alzheimer Disease

(2012) Akihiko Hoshi et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Gut microbiota and gastrointestinal health: current concepts and future directions

(2012) Q. Aziz et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Amyloid Precursor Protein and Proinflammatory Changes Are Regulated in Brain and Adipose Tissue in a Murine Model of High Fat Diet-Induced Obesity

(2012) Kendra L. Puig et al.   PLoS One

Withania somnifera reverses Alzheimer's disease pathology by enhancing low-density lipoprotein receptor-related protein in liver

(2012) N. Sehgal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Higher reported saturated fat and refined sugar intake is associated with reduced hippocampal-dependent memory and sensitivity to interoceptive signals.

(2011) Heather M. Francis et al.   BEHAVIORAL NEUROSCIENCE

Saturated fatty acids activate microglia via Toll-like receptor 4/NF-κB signalling

(2011) Zhen Wang et al.   BRITISH JOURNAL OF NUTRITION

Inflammation Is Necessary for Long-Term but Not Short-Term High-Fat Diet-Induced Insulin Resistance

(2011) Y. S. Lee et al.   DIABETES

Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β

(2011) Nicolas Dupont et al.   EMBO JOURNAL

Greater Fructose Consumption Is Associated with Cardiometabolic Risk Markers and Visceral Adiposity in Adolescents

(2011) Norman K. Pollock et al.   JOURNAL OF NUTRITION

Regulation of Inflammation by Short Chain Fatty Acids

(2011) Marco A.R. Vinolo et al.   Nutrients

Adverse Associations between Visceral Adiposity, Brain Structure, and Cognitive Performance in Healthy Elderly

(2011) Vivian Isaac et al.   Frontiers in Aging Neuroscience

Insulin Resistance and Alzheimer-like Reductions in Regional Cerebral Glucose Metabolism for Cognitively Normal Adults With Prediabetes or Early Type 2 Diabetes

(2010) Laura D. Baker et al.   ARCHIVES OF NEUROLOGY

Increased Food Intake Leads to Obesity and Insulin Resistance in the Tg2576 Alzheimer’s Disease Mouse Model

(2010) Motoyuki Kohjima et al.   ENDOCRINOLOGY

Aquaporin Expression in the Brains of Patients With or Without Cerebral Amyloid Angiopathy

(2010) Parham Moftakhar et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Hypercholesterolemia in rats impairs the cholinergic system and leads to memory deficits

(2010) Celine Ullrich et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Western diet consumption and cognitive impairment: Links to hippocampal dysfunction and obesity

(2010) Scott E. Kanoski et al.   PHYSIOLOGY & BEHAVIOR

Cognitive impairment following high fat diet consumption is associated with brain inflammation

(2009) Paul J. Pistell et al.   JOURNAL OF NEUROIMMUNOLOGY

Histone deacetylase inhibitors up-regulate astrocyte GDNF and BDNF gene transcription and protect dopaminergic neurons

(2008) Xuefei Wu et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice

(2008) Lakshmi Thirumangalakudi et al.   JOURNAL OF NEUROCHEMISTRY

High-fat diet aggravates amyloid-beta and tau pathologies in the 3xTg-AD mouse model

(2008) Carl Julien et al.   NEUROBIOLOGY OF AGING