Increased Levels of 27-Hydroxycholesterol Induced by Dietary Cholesterol in Brain Contribute to Learning and Memory Impairment in Rats

A High-Cholesterol Diet Increases 27-Hydroxycholesterol and Modifies Estrogen Receptor Expression and Neurodegeneration in Rabbit Hippocampus

(2017) Sylwia W. Brooks et al.   JOURNAL OF ALZHEIMERS DISEASE

Cholesterol as a modifying agent of the neurovascular unit structure and function under physiological and pathological conditions

(2017) Ewelina Czuba et al.   METABOLIC BRAIN DISEASE

27-Hydroxycholesterol regulates cholesterol synthesis and transport in C6 glioma cells

(2017) Yu An et al.   NEUROTOXICOLOGY

Neuroprotective effects of phytosterol esters against high cholesterol-induced cognitive deficits in aged rat

(2017) Xu Rui et al.   Food & Function

Endolysosome Mechanisms Associated with Alzheimer's Disease-like Pathology in Rabbits Ingesting Cholesterol-Enriched Diet

(2017) Xuesong Chen et al.   JOURNAL OF ALZHEIMERS DISEASE

Lysosomal cathepsins and their regulation in aging and neurodegeneration

(2016) Veronika Stoka et al.   AGEING RESEARCH REVIEWS

Cholesterol, 24-Hydroxycholesterol, and 27-Hydroxycholesterol as Surrogate Biomarkers in Cerebrospinal Fluid in Mild Cognitive Impairment and Alzheimer’s Disease: A Meta-Analysis

(2016) Hua-Long Wang et al.   JOURNAL OF ALZHEIMERS DISEASE

Relationship between oxysterols and mild cognitive impairment in the elderly: a case–control study

(2016) Quanri Liu et al.   Lipids in Health and Disease

Changes in astrocyte functional markers and β-amyloid metabolism-related proteins in the early stages of hypercholesterolemia

(2016) Y.L. Chen et al.   NEUROSCIENCE

Increased Aβ pathology in aged Tg2576 mice born to mothers fed a high fat diet

(2016) Shereen Nizari et al.   Scientific Reports

Changes in brain oxysterols at different stages of Alzheimer's disease: Their involvement in neuroinflammation

(2016) Gabriella Testa et al.   Redox Biology

27-Hydroxycholesterol mediates negative effects of dietary cholesterol on cognition in mice

(2015) Maura Heverin et al.   BEHAVIOURAL BRAIN RESEARCH

CYP46A1 inhibition, brain cholesterol accumulation and neurodegeneration pave the way for Alzheimer’s disease

(2015) Fathia Djelti et al.   BRAIN

Lovastatin Differentially Affects Neuronal Cholesterol and Amyloid-βProductionin vivoandin vitro

(2015) Aydé Mendoza-Oliva et al.   CNS Neuroscience & Therapeutics

27-Hydroxycholesterol contributes to disruptive effects on learning and memory by modulating cholesterol metabolism in the rat brain

(2015) D.-D. Zhang et al.   NEUROSCIENCE

Oxidized cholesterol as the driving force behind the development of Alzheimer’s disease

(2015) Paola Gamba et al.   Frontiers in Aging Neuroscience

Cholesterol metabolism and homeostasis in the brain

(2015) Juan Zhang et al.   Protein & Cell

More than Cholesterol Transporters: Lipoprotein Receptors in CNS Function and Neurodegeneration

(2014) Courtney Lane-Donovan et al.   NEURON

Autophagy failure in Alzheimer's disease and the role of defective lysosomal acidification

(2013) Devin M. Wolfe et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Markers of cholesterol transport are associated with amyloid deposition in the brain

(2013) Timothy M. Hughes et al.   NEUROBIOLOGY OF AGING

Protective effects of bilobalide on Aβ25–35 induced learning and memory impairments in male rats

(2013) Yanyan Yin et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Gadd153 and NF-κB Crosstalk Regulates 27-Hydroxycholesterol-Induced Increase in BACE1 and β-Amyloid Production in Human Neuroblastoma SH-SY5Y Cells

(2013) Gurdeep Marwarha et al.   PLoS One

A high cholesterol diet ameliorates hippocampus-related cognitive and pathological deficits in ovariectomized mice

(2012) Liu Li et al.   BEHAVIOURAL BRAIN RESEARCH

Endolysosome involvement in LDL cholesterol-induced Alzheimer's disease-like pathology in primary cultured neurons

(2012) Liang Hui et al.   LIFE SCIENCES

Dietary cholesterol alters memory and synaptic structural plasticity in young rat brain

(2012) Bai-liu Ya et al.   NEUROLOGICAL SCIENCES

Reduced Fear Memory and Anxiety-like Behavior in Mice Lacking Formylpeptide Receptor 1

(2011) Ji-Liang Gao et al.   BEHAVIOR GENETICS

Silencing GADD153/CHOP Gene Expression Protects against Alzheimer's Disease-Like Pathology Induced by 27-Hydroxycholesterol in Rabbit Hippocampus

(2011) Jaya R. P. Prasanthi et al.   PLoS One

Liver X Receptor Agonist Treatment Ameliorates Amyloid Pathology and Memory Deficits Caused by High-Fat Diet in APP23 Mice

(2010) N. F. Fitz et al.   JOURNAL OF NEUROSCIENCE

The oxysterol 27-hydroxycholesterol increases β-amyloid and oxidative stress in retinal pigment epithelial cells

(2010) Bhanu Dasari et al.   BMC Ophthalmology