标题
Blood-Brain Barrier Dysfunction and the Pathogenesis of Alzheimer’s Disease
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 18, Issue 9, Pages 1965
出版商
MDPI AG
发表日期
2017-09-13
DOI
10.3390/ijms18091965
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The role of peripheral immune cells in the CNS in steady state and disease
- (2017) Marco Prinz et al. NATURE NEUROSCIENCE
- Association of Perivascular Localization of Aquaporin-4 With Cognition and Alzheimer Disease in Aging Brains
- (2017) Douglas M. Zeppenfeld et al. JAMA Neurology
- Impact of sex and APOE4 on cerebral amyloid angiopathy in Alzheimer’s disease
- (2016) Mitsuru Shinohara et al. ACTA NEUROPATHOLOGICA
- Vascular basement membranes as pathways for the passage of fluid into and out of the brain
- (2016) Alan W. J. Morris et al. ACTA NEUROPATHOLOGICA
- Vascular contributions to cognitive impairment, clinical Alzheimer's disease, and dementia in older persons
- (2016) A. Kapasi et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Apolipoprotein E as a Therapeutic Target in Alzheimer’s Disease: A Review of Basic Research and Clinical Evidence
- (2016) Yu Yamazaki et al. CNS DRUGS
- Hyperglycemia Increases the Production of Amyloid Beta-Peptide Leading to Decreased Endothelial Tight Junction
- (2016) A-Ching Chao et al. CNS Neuroscience & Therapeutics
- A 40 Reduces P-Glycoprotein at the Blood-Brain Barrier through the Ubiquitin-Proteasome Pathway
- (2016) A. M. S. Hartz et al. JOURNAL OF NEUROSCIENCE
- Pericytes of the neurovascular unit: key functions and signaling pathways
- (2016) Melanie D Sweeney et al. NATURE NEUROSCIENCE
- In vitro discrimination of the role of LRP1 at the BBB cellular level: Focus on brain capillary endothelial cells and brain pericytes
- (2015) Pietra Candela et al. BRAIN RESEARCH
- ZO-1 controls endothelial adherens junctions, cell–cell tension, angiogenesis, and barrier formation
- (2015) Olga Tornavaca et al. JOURNAL OF CELL BIOLOGY
- Endothelial LRP1 transports amyloid-β1–42 across the blood-brain barrier
- (2015) Steffen E. Storck et al. JOURNAL OF CLINICAL INVESTIGATION
- Aβ1-42oligomer-induced leakage in anin vitroblood-brain barrier model is associated with up-regulation of RAGE and metalloproteinases, and down-regulation of tight junction scaffold proteins
- (2015) Wenbin Wan et al. JOURNAL OF NEUROCHEMISTRY
- Neuroinflammation in Alzheimer's disease
- (2015) Michael T Heneka et al. LANCET NEUROLOGY
- Neutrophils promote Alzheimer's disease–like pathology and cognitive decline via LFA-1 integrin
- (2015) Elena Zenaro et al. NATURE MEDICINE
- GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration
- (2015) Ethan A Winkler et al. NATURE NEUROSCIENCE
- Blood-Brain Barrier Breakdown in the Aging Human Hippocampus
- (2015) Axel Montagne et al. NEURON
- Early changes in extracellular matrix in Alzheimer's disease
- (2015) F.-X. Lepelletier et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- The Molecular Constituents of the Blood–Brain Barrier
- (2015) Brian Wai Chow et al. TRENDS IN NEUROSCIENCES
- The Blood–Brain Barrier
- (2015) Richard Daneman et al. Cold Spring Harbor Perspectives in Biology
- Cardiovascular risk factors and future risk of Alzheimer’s disease
- (2014) Renée FAG de Bruijn et al. BMC Medicine
- Ablation of MMP9 Gene Ameliorates Paracellular Permeability and Fibrinogen–Amyloid Beta Complex Formation during Hyperhomocysteinemia
- (2014) Nino Muradashvili et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease
- (2014) Tara L. Spires-Jones et al. NEURON
- Aβ1–42 reduces P-glycoprotein in the blood–brain barrier through RAGE–NF-κB signaling
- (2014) R Park et al. Cell Death & Disease
- The Cerebrovascular Basement Membrane: Role in the Clearance of β-amyloid and Cerebral Amyloid Angiopathy
- (2014) Alan W. J. Morris et al. Frontiers in Aging Neuroscience
- The low-density lipoprotein receptor-related protein 1 and amyloid-β clearance in Alzheimer’s disease
- (2014) Takahisa Kanekiyo et al. Frontiers in Aging Neuroscience
- Regional differences in the morphological and functional effects of aging on cerebral basement membranes and perivascular drainage of amyloid-β from the mouse brain
- (2013) Cheryl A. Hawkes et al. AGING CELL
- Blood–Brain Barrier Dysfunction as a Cause and Consequence of Alzheimer's Disease
- (2013) Michelle A Erickson et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- RAGE regulation and signaling in inflammation and beyond
- (2013) Katrin Kierdorf et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy
- (2013) Chia-Chen Liu et al. Nature Reviews Neurology
- Alzheimer disease in the United States (2010-2050) estimated using the 2010 census
- (2013) L. E. Hebert et al. NEUROLOGY
- Innate Immunity in the CNS: Redefining the Relationship between the CNS and Its Environment
- (2013) Antoine Lampron et al. NEURON
- Claudins and the Modulation of Tight Junction Permeability
- (2013) Dorothee Günzel et al. PHYSIOLOGICAL REVIEWS
- GLUT1 deficiency syndrome 2013: Current state of the art
- (2013) Valentina De Giorgis et al. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
- Pericyte loss influences Alzheimer-like neurodegeneration in mice
- (2013) Abhay P. Sagare et al. Nature Communications
- Laminin isoforms in endothelial and perivascular basement membranes
- (2013) Lema F. Yousif et al. Cell Adhesion & Migration
- Neuropathological Alterations in Alzheimer Disease
- (2013) A. Serrano-Pozo et al. Cold Spring Harbor Perspectives in Medicine
- Proteolytic Degradation of Amyloid -Protein
- (2013) T. Saido et al. Cold Spring Harbor Perspectives in Medicine
- The blood-brain barrier in health and disease
- (2012) Richard Daneman ANNALS OF NEUROLOGY
- Cerebrovascular atherosclerosis correlates with Alzheimer pathology in neurodegenerative dementias
- (2012) M. Yarchoan et al. BRAIN
- Deficiency in Mural Vascular Cells Coincides with Blood-Brain Barrier Disruption in Alzheimer's Disease
- (2012) Jesse D. Sengillo et al. BRAIN PATHOLOGY
- Immunologic Privilege in the Central Nervous System and the Blood–Brain Barrier
- (2012) Leslie L Muldoon et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- A multimodal RAGE-specific inhibitor reduces amyloid β–mediated brain disorder in a mouse model of Alzheimer disease
- (2012) Rashid Deane et al. JOURNAL OF CLINICAL INVESTIGATION
- Characteristics of Aquaporin Expression Surrounding Senile Plaques and Cerebral Amyloid Angiopathy in Alzheimer Disease
- (2012) Akihiko Hoshi et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- A 1-42-RAGE Interaction Disrupts Tight Junctions of the Blood-Brain Barrier Via Ca2+-Calcineurin Signaling
- (2012) S.-Y. Kook et al. JOURNAL OF NEUROSCIENCE
- Neuroinflammation and Blood-Brain Barrier Changes in Capillary Amyloid Angiopathy
- (2012) Anna Carrano et al. Neurodegenerative Diseases
- Disruption of Arterial Perivascular Drainage of Amyloid-β from the Brains of Mice Expressing the Human APOE ε4 Allele
- (2012) Cheryl A. Hawkes et al. PLoS One
- A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid
- (2012) J. J. Iliff et al. Science Translational Medicine
- Vascular β-amyloid and early astrocyte alterations impair cerebrovascular function and cerebral metabolism in transgenic arcAβ mice
- (2011) Mario Merlini et al. ACTA NEUROPATHOLOGICA
- Amyloid Beta Induces Oxidative Stress-Mediated Blood–Brain Barrier Changes in Capillary Amyloid Angiopathy
- (2011) Anna Carrano et al. ANTIOXIDANTS & REDOX SIGNALING
- Blood–brain barrier P-glycoprotein function in Alzheimer's disease
- (2011) Daniëlle M. E. van Assema et al. BRAIN
- Extracellular matrix and matrix receptors in blood-brain barrier formation and stroke
- (2011) Kim M. Baeten et al. Developmental Neurobiology
- Bidirectional control of arteriole diameter by astrocytes
- (2011) Grant R. J. Gordon et al. EXPERIMENTAL PHYSIOLOGY
- Endocrine cells and blood vessels work in tandem to generate hormone pulses
- (2011) Marie Schaeffer et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- Neurovascular dysfunction, inflammation and endothelial activation: Implications for the pathogenesis of Alzheimer's disease
- (2011) Paula Grammas Journal of Neuroinflammation
- Central nervous system pericytes in health and disease
- (2011) Ethan A Winkler et al. NATURE NEUROSCIENCE
- Blood-brain barrier disturbance in patients with Alzheimer's disease is related to vascular factors
- (2010) K. Blennow et al. ACTA NEUROLOGICA SCANDINAVICA
- Effect of cAMP derivates on assembly and maintenance of tight junctions in human umbilical vein endothelial cells
- (2010) Michaela Beese et al. BMC CELL BIOLOGY
- The RAGE Axis
- (2010) Shi Fang Yan et al. CIRCULATION RESEARCH
- Reduction of Brain β-Amyloid (Aβ) by Fluvastatin, a Hydroxymethylglutaryl-CoA Reductase Inhibitor, through Increase in Degradation of Amyloid Precursor Protein C-terminal Fragments (APP-CTFs) and Aβ Clearance
- (2010) Mitsuru Shinohara et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Vascular inflammation in central nervous system diseases: adhesion receptors controlling leukocyte-endothelial interactions
- (2010) B. Rossi et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Lack of brain-to-blood efflux transport activity of low-density lipoprotein receptor-related protein-1 (LRP-1) for amyloid-β peptide(1-40) in mouse: involvement of an LRP-1-independent pathway
- (2010) Shingo Ito et al. JOURNAL OF NEUROCHEMISTRY
- Aquaporin Expression in the Brains of Patients With or Without Cerebral Amyloid Angiopathy
- (2010) Parham Moftakhar et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Restoring Blood-Brain Barrier P-Glycoprotein Reduces Brain Amyloid- in a Mouse Model of Alzheimer's Disease
- (2010) A. M. S. Hartz et al. MOLECULAR PHARMACOLOGY
- Glial and neuronal control of brain blood flow
- (2010) David Attwell et al. NATURE
- Pericytes regulate the blood–brain barrier
- (2010) Annika Armulik et al. NATURE
- Pericytes are required for blood–brain barrier integrity during embryogenesis
- (2010) Richard Daneman et al. NATURE
- LRP1 mediates bidirectional transcytosis of amyloid-β across the blood-brain barrier
- (2010) Thorsten Pflanzner et al. NEUROBIOLOGY OF AGING
- Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging
- (2010) Robert D. Bell et al. NEURON
- The Mouse Blood-Brain Barrier Transcriptome: A New Resource for Understanding the Development and Function of Brain Endothelial Cells
- (2010) Richard Daneman et al. PLoS One
- Role of Astrocytes in Brain Function and Disease
- (2010) Marta Sidoryk-Wegrzynowicz et al. TOXICOLOGIC PATHOLOGY
- The expanding phenotype of GLUT1-deficiency syndrome
- (2009) Knut Brockmann BRAIN & DEVELOPMENT
- Uniquely Hominid Features of Adult Human Astrocytes
- (2009) N. A. Oberheim et al. JOURNAL OF NEUROSCIENCE
- ABCG2 Is Upregulated in Alzheimer's Brain with Cerebral Amyloid Angiopathy and May Act as a Gatekeeper at the Blood-Brain Barrier for A 1-40 Peptides
- (2009) H. Xiong et al. JOURNAL OF NEUROSCIENCE
- Is it appropriate to use albumin CSF/plasma ratio to assess blood brain barrier permeability?
- (2009) Ruo-Li Chen NEUROBIOLOGY OF AGING
- Vascular amyloid alters astrocytic water and potassium channels in mouse models and humans with Alzheimer's disease
- (2009) D.M. Wilcock et al. NEUROSCIENCE
- Wnt/ -catenin signaling is required for CNS, but not non-CNS, angiogenesis
- (2009) R. Daneman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Blood–brain barrier permeability in Alzheimer's disease: a case–control MRI study
- (2009) John M. Starr et al. PSYCHIATRY RESEARCH-NEUROIMAGING
- Hippocampal RAGE immunoreactivity in early and advanced Alzheimer's disease
- (2008) Miles C. Miller et al. BRAIN RESEARCH
- Structural Changes in Alzheimers Disease Brain Microvessels
- (2008) Alexander Christov et al. Current Alzheimer Research
- The Low Density Lipoprotein Receptor-related Protein 1 Mediates Uptake of Amyloid β Peptides in anin VitroModel of the Blood-Brain Barrier Cells
- (2008) Kaoru Yamada et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The role of adherens junctions and VE-cadherin in the control of vascular permeability
- (2008) E. Dejana et al. JOURNAL OF CELL SCIENCE
- Perivascular Spaces and the Two Steps to Neuroinflammation
- (2008) Trevor Owens et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- LRP promotes endocytosis and degradation, but not transcytosis, of the amyloid-β peptide in a blood–brain barrier in vitro model
- (2008) Babak Nazer et al. NEUROBIOLOGY OF DISEASE
- The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
- (2008) Berislav V. Zlokovic NEURON
- VE-Cadherin
- (2007) Dietmar Vestweber ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Blood–brain barrier: Ageing and microvascular disease – systematic review and meta-analysis
- (2007) Andrew J. Farrall et al. NEUROBIOLOGY OF AGING
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started