Reactive astrocytes: The nexus of pathological and clinical hallmarks of Alzheimer’s disease
出版年份 2021 全文链接
标题
Reactive astrocytes: The nexus of pathological and clinical hallmarks of Alzheimer’s disease
作者
关键词
Astrocytes, Reactive astrocytes, Alzheimer’s disease, Dementia, Neuroinflammation, Neurodegeneration
出版物
AGEING RESEARCH REVIEWS
Volume 68, Issue -, Pages 101335
出版商
Elsevier BV
发表日期
2021-04-01
DOI
10.1016/j.arr.2021.101335
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Reactive astrocyte nomenclature, definitions, and future directions
- (2021) Carole Escartin et al. NATURE NEUROSCIENCE
- Amyloid Fibril–Induced Astrocytic Glutamate Transporter Disruption Contributes to Complement C1q-Mediated Microglial Pruning of Glutamatergic Synapses
- (2020) Jiang Wu et al. MOLECULAR NEUROBIOLOGY
- MAFG-driven astrocytes promote CNS inflammation
- (2020) Michael A. Wheeler et al. NATURE
- Complex roles for reactive astrocytes in the triple transgenic mouse model of Alzheimer disease
- (2020) Océane Guillemaud et al. NEUROBIOLOGY OF AGING
- Metabolic Regulation of Glial Phenotypes: Implications in Neuron–Glia Interactions and Neurological Disorders
- (2020) Ruqayya Afridi et al. Frontiers in Cellular Neuroscience
- Identification of region-specific astrocyte subtypes at single cell resolution
- (2020) Mykhailo Y. Batiuk et al. Nature Communications
- APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline
- (2020) Axel Montagne et al. NATURE
- Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation
- (2020) Erik C. B. Johnson et al. NATURE MEDICINE
- Going the Extra (Synaptic) Mile: Excitotoxicity as the Road Toward Neurodegenerative Diseases
- (2020) Adam Armada-Moreira et al. Frontiers in Cellular Neuroscience
- Astroglia and Tau: New Perspectives
- (2020) Gabor G. Kovacs Frontiers in Aging Neuroscience
- Reconstruction of the human blood–brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes
- (2020) Joel W. Blanchard et al. NATURE MEDICINE
- CD49f Is a Novel Marker of Functional and Reactive Human iPSC-Derived Astrocytes
- (2020) Lilianne Barbar et al. NEURON
- The Role of Astrocytes in CNS Inflammation
- (2020) Federico Giovannoni et al. TRENDS IN IMMUNOLOGY
- Astrocytic Ca2+ signaling is reduced during sleep and is involved in the regulation of slow wave sleep
- (2020) Laura Bojarskaite et al. Nature Communications
- Astrocyte Reactivity: Subtypes, States, and Functions in CNS Innate Immunity
- (2020) Michael V. Sofroniew TRENDS IN IMMUNOLOGY
- Inhibition of Stat3‐mediated astrogliosis ameliorates pathology in an Alzheimer's disease model
- (2019) Nicole Reichenbach et al. EMBO Molecular Medicine
- Reduced non–rapid eye movement sleep is associated with tau pathology in early Alzheimer’s disease
- (2019) Brendan P. Lucey et al. Science Translational Medicine
- The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans
- (2019) Jerrah K. Holth et al. SCIENCE
- Modulation of SPARC/Hevin Proteins in Alzheimer’s Disease Brain Injury
- (2019) Maximilian Strunz et al. JOURNAL OF ALZHEIMERS DISEASE
- Targeting pericytes for neurovascular regeneration
- (2019) Mohammad Hossein Geranmayeh et al. Cell Communication and Signaling
- Glymphatic System Function in Relation to Anesthesia and Sleep States
- (2019) Helene Benveniste et al. ANESTHESIA AND ANALGESIA
- Molecularly defined cortical astroglia subpopulation modulates neurons via secretion of Norrin
- (2019) Sean J. Miller et al. NATURE NEUROSCIENCE
- Astroglial Calcium Signaling in Aging and Alzheimer's Disease
- (2019) Alexei Verkhratsky Cold Spring Harbor Perspectives in Biology
- The overlap between epilepsy and Alzheimer’s disease and the consequences for treatment
- (2019) Graham Powell et al. Expert Review of Neurotherapeutics
- The astrocyte transcriptome in EAE optic neuritis shows complement activation and reveals a sex difference in astrocytic C3 expression
- (2019) Alessia Tassoni et al. Scientific Reports
- Astrocyte Function Is Affected by Aging and Not Alzheimer’s Disease: A Preliminary Investigation in Hippocampi of 3xTg-AD Mice
- (2019) Maria Rosanna Bronzuoli et al. Frontiers in Pharmacology
- Questions and (some) answers on reactive astrocytes
- (2019) Carole Escartin et al. GLIA
- NMDA Receptor Antagonists: Repositioning of Memantine as a Multitargeting Agent for Alzheimer's Therapy
- (2019) Md. Tanvir Kabir et al. CURRENT PHARMACEUTICAL DESIGN
- Time course of neuropathological events in hyperhomocysteinemic amyloid depositing mice reveals early neuroinflammatory changes that precede amyloid changes and cerebrovascular events
- (2019) Erica M. Weekman et al. Journal of Neuroinflammation
- Cerebral amyloid angiopathy and Alzheimer disease — one peptide, two pathways
- (2019) Steven M. Greenberg et al. Nature Reviews Neurology
- Effect of sleep on overnight cerebrospinal fluid amyloid β kinetics
- (2018) Brendan P. Lucey et al. ANNALS OF NEUROLOGY
- Two Classes of Secreted Synaptic Organizers in the Central Nervous System
- (2018) Michisuke Yuzaki Annual Review of Physiology
- Neuronal and Extraneuronal Nicotinic Acetylcholine Receptors
- (2018) Michele Zoli et al. Current Neuropharmacology
- An emerging role of astrocytes in vascular contributions to cognitive impairment and dementia
- (2018) Brittani R. Price et al. JOURNAL OF NEUROCHEMISTRY
- Gliotransmission: Beyond Black-and-White
- (2018) Iaroslav Savtchouk et al. JOURNAL OF NEUROSCIENCE
- Multiple Lines of Evidence Indicate That Gliotransmission Does Not Occur under Physiological Conditions
- (2018) Todd A. Fiacco et al. JOURNAL OF NEUROSCIENCE
- Specific deletion connexin43 in astrocyte ameliorates cognitive dysfunction in APP/PS1 mice
- (2018) Ren Runan et al. LIFE SCIENCES
- Astroglial Responses to Amyloid-Beta Progression in a Mouse Model of Alzheimer’s Disease
- (2018) Malin Olsen et al. MOLECULAR IMAGING AND BIOLOGY
- Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders
- (2018) Melanie D. Sweeney et al. Nature Reviews Neurology
- Attenuation of reactive gliosis in stroke-injured mouse brain does not affect neurogenesis from grafted human iPSC-derived neural progenitors
- (2018) Cecilia Laterza et al. PLoS One
- β-Amyloid accumulation in the human brain after one night of sleep deprivation
- (2018) Ehsan Shokri-Kojori et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Aging Astrocyte Transcriptome from Multiple Regions of the Mouse Brain
- (2018) Matthew M. Boisvert et al. Cell Reports
- Ca2+, Astrocyte Activation and Calcineurin/NFAT Signaling in Age-Related Neurodegenerative Diseases
- (2018) Pradoldej Sompol et al. Frontiers in Aging Neuroscience
- Deciphering the Astrocyte Reaction in Alzheimer’s Disease
- (2018) Beatriz G. Perez-Nievas et al. Frontiers in Aging Neuroscience
- Genetic variation in Aquaporin-4 moderates the relationship between sleep and brain Aβ-amyloid burden
- (2018) Stephanie R. Rainey-Smith et al. Translational Psychiatry
- Region- and Age-Specific Changes in Glutamate Transport in the AβPP23 Mouse Model for Alzheimer's Disease
- (2018) Anneleen Schallier et al. JOURNAL OF ALZHEIMERS DISEASE
- Identification of SPARC-like 1 Protein as Part of a Biomarker Panel for Alzheimer's Disease in Cerebrospinal Fluid
- (2018) Baharak Vafadar-Isfahani et al. JOURNAL OF ALZHEIMERS DISEASE
- Seizure in Alzheimer’s Disease: An Underestimated Phenomenon
- (2018) Marjan Asadollahi et al. American Journal of Alzheimers Disease and Other Dementias
- Basal fatty acid oxidation increases after recurrent low glucose in human primary astrocytes
- (2018) Paul G. Weightman Potter et al. DIABETOLOGIA
- Ceftriaxone Improves Cognitive Function and Upregulates GLT-1-Related Glutamate-Glutamine Cycle in APP/PS1 Mice
- (2018) ShuJuan Fan et al. JOURNAL OF ALZHEIMERS DISEASE
- AP‐1 and the injury response of the GFAP gene
- (2018) Michael Brenner et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Astrocyte expression of the Drosophila TNF-alpha homologue, Eiger, regulates sleep in flies
- (2018) William M. Vanderheyden et al. PLoS Genetics
- Glycolysis Paradigm Shift Dictates a Reevaluation of Glucose and Oxygen Metabolic Rates of Activated Neural Tissue
- (2018) Avital Schurr Frontiers in Neuroscience
- Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer’s disease
- (2018) Kelly Ceyzériat et al. Acta Neuropathologica Communications
- Alpha 7 nicotinic acetylcholine receptor and its effects on Alzheimer's disease
- (2018) Kai-Ge Ma et al. NEUROPEPTIDES
- AQP4 Association with Amyloid Deposition and Astrocyte Pathology in the Tg-ArcSwe Mouse Model of Alzheimer’s Disease
- (2017) Jing Yang et al. JOURNAL OF ALZHEIMERS DISEASE
- Role of Glutamate and NMDA Receptors in Alzheimer’s Disease
- (2017) Rui Wang et al. JOURNAL OF ALZHEIMERS DISEASE
- Regional astrocyte IFN signaling restricts pathogenesis during neurotropic viral infection
- (2017) Brian P. Daniels et al. JOURNAL OF CLINICAL INVESTIGATION
- Neuroinflammatory responses in Alzheimer’s disease
- (2017) Cira Dansokho et al. JOURNAL OF NEURAL TRANSMISSION
- Calcineurin/NFAT Signaling in Activated Astrocytes Drives Network Hyperexcitability in Aβ-Bearing Mice
- (2017) Pradoldej Sompol et al. JOURNAL OF NEUROSCIENCE
- Epileptic activity in Alzheimer's disease: causes and clinical relevance
- (2017) Keith A Vossel et al. LANCET NEUROLOGY
- Subtle blood-brain barrier leakage rate and spatial extent: Considerations for dynamic contrast-enhanced MRI
- (2017) Harm J. van de Haar et al. MEDICAL PHYSICS
- Neurotoxic reactive astrocytes are induced by activated microglia
- (2017) Shane A. Liddelow et al. NATURE
- Therapeutic potential of α7 nicotinic receptor agonists to regulate neuroinflammation in neurodegenerative diseases
- (2017) Laura Foucault-Fruchard et al. Neural Regeneration Research
- Early hippocampal hyperexcitability in PS2APP mice: role of mutant PS2 and APP
- (2017) Roberto Fontana et al. NEUROBIOLOGY OF AGING
- Peripheral administration of the soluble TNF inhibitor XPro1595 modifies brain immune cell profiles, decreases beta-amyloid plaque load, and rescues impaired long-term potentiation in 5xFAD mice
- (2017) Kathryn P. MacPherson et al. NEUROBIOLOGY OF DISEASE
- Sex differences in Alzheimer risk
- (2017) Lisa Mosconi et al. NEUROLOGY
- The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease
- (2017) Costantino Iadecola NEURON
- Cell Biology of Astrocyte-Synapse Interactions
- (2017) Nicola J. Allen et al. NEURON
- Ageing causes prominent neurovascular dysfunction associated with loss of astrocytic contacts and gliosis
- (2017) J. Duncombe et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Cell-specific and region-specific transcriptomics in the multiple sclerosis model: Focus on astrocytes
- (2017) Noriko Itoh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Three-dimensional Ca2+imaging advances understanding of astrocyte biology
- (2017) Erika Bindocci et al. SCIENCE
- Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice
- (2017) Qiaoqiao Shi et al. Science Translational Medicine
- Association of Perivascular Localization of Aquaporin-4 With Cognition and Alzheimer Disease in Aging Brains
- (2017) Douglas M. Zeppenfeld et al. JAMA Neurology
- Perimenopause and emergence of an Alzheimer’s bioenergetic phenotype in brain and periphery
- (2017) Lisa Mosconi et al. PLoS One
- The role of glial-specific Kir4.1 in normal and pathological states of the CNS
- (2016) Sinifunanya E. Nwaobi et al. ACTA NEUROPATHOLOGICA
- Fatty acid-induced astrocyte ketone production and the control of food intake
- (2016) Christelle Le Foll et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Can ketones compensate for deteriorating brain glucose uptake during aging? Implications for the risk and treatment of Alzheimer's disease
- (2016) Stephen C. Cunnane et al. Annals of the New York Academy of Sciences
- Calcineurin proteolysis in astrocytes: Implications for impaired synaptic function
- (2016) Melanie M. Pleiss et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- The role of cerebrovascular disease when there is concomitant Alzheimer disease
- (2016) Prashanthi Vemuri et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Vascular contributions to cognitive impairment, clinical Alzheimer's disease, and dementia in older persons
- (2016) A. Kapasi et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Neurovascular dysfunction and neurodegeneration in dementia and Alzheimer's disease
- (2016) Amy R. Nelson et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Diverging longitudinal changes in astrocytosis and amyloid PET in autosomal dominant Alzheimer’s disease
- (2016) Elena Rodriguez-Vieitez et al. BRAIN
- Astroglial connexin43 contributes to neuronal suffering in a mouse model of Alzheimer’s disease
- (2016) C Yi et al. CELL DEATH AND DIFFERENTIATION
- Modulatory effects of α7 nAChRs on the immune system and its relevance for CNS disorders
- (2016) Hans O. Kalkman et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The Science of Vascular Contributions to Cognitive Impairment and Dementia (VCID): A Framework for Advancing Research Priorities in the Cerebrovascular Biology of Cognitive Decline
- (2016) Roderick A. Corriveau et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Expression of A152T human tau causes age‐dependent neuronal dysfunction and loss in transgenic mice
- (2016) Sumihiro Maeda et al. EMBO REPORTS
- Blockade of the Interaction of Calcineurin with FOXO in Astrocytes Protects Against Amyloid-β-Induced Neuronal Death
- (2016) Ana M. Fernandez et al. JOURNAL OF ALZHEIMERS DISEASE
- The Translational Significance of the Neurovascular Unit
- (2016) Heather L. McConnell et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Role of transient receptor potential ankyrin 1 channels in Alzheimer’s disease
- (2016) Kuan-I Lee et al. Journal of Neuroinflammation
- Neuroprotective Effects of the Glutamate Transporter Activator (R)-(−)-5-methyl-1-nicotinoyl-2-pyrazoline (MS-153) following Traumatic Brain Injury in the Adult Rat
- (2016) Andréia Cristina Karklin Fontana et al. JOURNAL OF NEUROTRAUMA
- The 'selfish brain' is regulated by aquaporins and autophagy under nutrient deprivation
- (2016) QIAO YE et al. Molecular Medicine Reports
- Age and Alzheimer’s disease gene expression profiles reversed by the glutamate modulator riluzole
- (2016) A C Pereira et al. MOLECULAR PSYCHIATRY
- Astrocytes mediate neurovascular signaling to capillary pericytes but not to arterioles
- (2016) Anusha Mishra et al. NATURE NEUROSCIENCE
- Inhibiting tumor necrosis factor-α before amyloidosis prevents synaptic deficits in an Alzheimer's disease model
- (2016) Chelsea Cavanagh et al. NEUROBIOLOGY OF AGING
- Astroglial glutamate transporters coordinate excitatory signaling and brain energetics
- (2016) Michael B. Robinson et al. NEUROCHEMISTRY INTERNATIONAL
- Imaging brain aerobic glycolysis as a marker of synaptic plasticity
- (2016) Pierre J. Magistretti PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Astrocytes regulate cortical state switching in vivo
- (2016) Kira E. Poskanzer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Blood-Brain Barrier Leakage in Patients with Early Alzheimer Disease
- (2016) Harm J. van de Haar et al. RADIOLOGY
- Complement and microglia mediate early synapse loss in Alzheimer mouse models
- (2016) S. Hong et al. SCIENCE
- Emerging Evidence for Pathogenesis of Sporadic Cerebral Small Vessel Disease
- (2016) Masafumi Ihara et al. STROKE
- Mapping synaptic glutamate transporter dysfunction in vivo to regions surrounding Aβ plaques by iGluSnFR two-photon imaging
- (2016) J. K. Hefendehl et al. Nature Communications
- Role of NMDA Receptor-Mediated Glutamatergic Signaling in Chronic and Acute Neuropathologies
- (2016) Francisco J. Carvajal et al. NEURAL PLASTICITY
- Establishment and Dysfunction of the Blood-Brain Barrier
- (2015) Zhen Zhao et al. CELL
- Astrocytosis precedes amyloid plaque deposition in Alzheimer APPswe transgenic mouse brain: a correlative positron emission tomography and in vitro imaging study
- (2015) Elena Rodriguez-Vieitez et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Blood–brain barrier endogenous transporters as therapeutic targets: a new model for small molecule CNS drug discovery
- (2015) William M Pardridge EXPERT OPINION ON THERAPEUTIC TARGETS
- The dynamic blood-brain barrier
- (2015) James Keaney et al. FEBS Journal
- Mechanisms underlying AQP4 accumulation in astrocyte endfeet
- (2015) Laura Maria Azzurra Camassa et al. GLIA
- GFAP and vimentin deficiency alters gene expression in astrocytes and microglia in wild-type mice and changes the transcriptional response of reactive glia in mouse model for Alzheimer's disease
- (2015) Willem Kamphuis et al. GLIA
- What is a pericyte?
- (2015) David Attwell et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Restored glial glutamate transporter EAAT2 function as a potential therapeutic approach for Alzheimer’s disease
- (2015) Kou Takahashi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The JAK/STAT3 Pathway Is a Common Inducer of Astrocyte Reactivity in Alzheimer's and Huntington's Diseases
- (2015) L. Ben Haim et al. JOURNAL OF NEUROSCIENCE
- Conditional Deletion of the Glutamate Transporter GLT-1 Reveals That Astrocytic GLT-1 Protects against Fatal Epilepsy While Neuronal GLT-1 Contributes Significantly to Glutamate Uptake into Synaptosomes
- (2015) G. T. Petr et al. JOURNAL OF NEUROSCIENCE
- Integration and Modulation of Intercellular Signaling Underlying Blood Flow Control
- (2015) Steven S. Segal JOURNAL OF VASCULAR RESEARCH
- Vascular Inward Rectifier K+Channels as External K+Sensors in the Control of Cerebral Blood Flow
- (2015) Thomas A. Longden et al. MICROCIRCULATION
- Dissecting the Contribution of Vascular Alterations and Aging to Alzheimer’s Disease
- (2015) Cátia Janota et al. MOLECULAR NEUROBIOLOGY
- Neutrophils promote Alzheimer's disease–like pathology and cognitive decline via LFA-1 integrin
- (2015) Elena Zenaro et al. NATURE MEDICINE
- Perimenopause as a neurological transition state
- (2015) Roberta D. Brinton et al. Nature Reviews Endocrinology
- Clearance systems in the brain—implications for Alzheimer disease
- (2015) Jenna M. Tarasoff-Conway et al. Nature Reviews Neurology
- Ceftriaxone ameliorates tau pathology and cognitive decline via restoration of glial glutamate transporter in a mouse model of Alzheimer's disease
- (2015) Joannee Zumkehr et al. NEUROBIOLOGY OF AGING
- Thrombospondin-1 prevents amyloid beta–mediated synaptic pathology in Alzheimer's disease
- (2015) Sung Min Son et al. NEUROBIOLOGY OF AGING
- The perimenopausal aging transition in the female rat brain: decline in bioenergetic systems and synaptic plasticity
- (2015) Fei Yin et al. NEUROBIOLOGY OF AGING
- Blood-Brain Barrier Breakdown in the Aging Human Hippocampus
- (2015) Axel Montagne et al. NEURON
- NFκB-Activated Astroglial Release of Complement C3 Compromises Neuronal Morphology and Function Associated with Alzheimer’s Disease
- (2015) Hong Lian et al. NEURON
- Contribution of reactive oxygen species to cerebral amyloid angiopathy, vasomotor dysfunction, and microhemorrhage in aged Tg2576 mice
- (2015) Byung Hee Han et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Topological analyses in APP/PS1 mice reveal that astrocytes do not migrate to amyloid-β plaques
- (2015) Elena Galea et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Altered intrinsic excitability of hippocampal CA1 pyramidal neurons in aged PDAPP mice
- (2015) Francesco Tamagnini et al. Frontiers in Cellular Neuroscience
- Role of amyloid peptides in vascular dysfunction and platelet dysregulation in Alzheimer’s disease
- (2015) Ilaria Canobbio et al. Frontiers in Cellular Neuroscience
- Elusive roles for reactive astrocytes in neurodegenerative diseases
- (2015) Lucile Ben Haim et al. Frontiers in Cellular Neuroscience
- Astrocyte Regulation of Blood Flow in the Brain
- (2015) Brian A. MacVicar et al. Cold Spring Harbor Perspectives in Biology
- Altered Theta Oscillations and Aberrant Cortical Excitatory Activity in the 5XFAD Model of Alzheimer’s Disease
- (2015) Magdalena Elisabeth Siwek et al. NEURAL PLASTICITY
- White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer's Disease
- (2015) Lauren P. Klosinski et al. EBioMedicine
- Astrocytic metabolic and inflammatory changes as a function of age
- (2014) Tianyi Jiang et al. AGING CELL
- Impairment of paravascular clearance pathways in the aging brain
- (2014) Benjamin T. Kress et al. ANNALS OF NEUROLOGY
- Epidemiologic studies of modifiable factors associated with cognition and dementia: systematic review and meta-analysis
- (2014) May A Beydoun et al. BMC PUBLIC HEALTH
- Sustained Down-regulation of β-Dystroglycan and Associated Dysfunctions of Astrocytic Endfeet in Epileptic Cerebral Cortex
- (2014) Asako Gondo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Neuronal activity regulates extracellular tau in vivo
- (2014) Kaoru Yamada et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Calcineurin and glial signaling: neuroinflammation and beyond
- (2014) Jennifer L Furman et al. Journal of Neuroinflammation
- Synaptic Glutamate Spillover Due to Impaired Glutamate Uptake Mediates Heroin Relapse
- (2014) H.-w. Shen et al. JOURNAL OF NEUROSCIENCE
- Dendritic Structural Degeneration Is Functionally Linked to Cellular Hyperexcitability in a Mouse Model of Alzheimer’s Disease
- (2014) Zuzana Šišková et al. NEURON
- Extrasynaptic NMDA Receptor in Excitotoxicity
- (2014) Xianju Zhou et al. NEUROSCIENTIST
- Astroglial cradle in the life of the synapse
- (2014) A. Verkhratsky et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Fatty Acids in Energy Metabolism of the Central Nervous System
- (2014) Alexander Panov et al. Biomed Research International
- Effect of 1 Night of Total Sleep Deprivation on Cerebrospinal Fluid β-Amyloid 42 in Healthy Middle-Aged Men
- (2014) Sharon Ooms et al. JAMA Neurology
- Astrocyte-Secreted Matricellular Proteins in CNS Remodelling during Development and Disease
- (2014) Emma V. Jones et al. NEURAL PLASTICITY
- Calcium dysregulation and neuroinflammation: Discrete and integrated mechanisms for age-related synaptic dysfunction
- (2013) Diana M. Sama et al. AGEING RESEARCH REVIEWS
- A Phenotypic Change But Not Proliferation Underlies Glial Responses in Alzheimer Disease
- (2013) Alberto Serrano-Pozo et al. AMERICAN JOURNAL OF PATHOLOGY
- A cytokine network involving brain-borne IL-1β, IL-1ra, IL-18, IL-6, and TNFα operates during long-term potentiation and learning
- (2013) Adriana del Rey et al. BRAIN BEHAVIOR AND IMMUNITY
- Inflammation-Induced Alteration of Astrocyte Mitochondrial Dynamics Requires Autophagy for Mitochondrial Network Maintenance
- (2013) Elisa Motori et al. Cell Metabolism
- Amyloid beta deregulates astroglial mGluR5-mediated calcium signaling via calcineurin and Nf-kB
- (2013) Dmitry Lim et al. GLIA
- Induction of Hyperhomocysteinemia Models Vascular Dementia by Induction of Cerebral Microhemorrhages and Neuroinflammation
- (2013) Tiffany L Sudduth et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Why does Brain Metabolism not Favor Burning of Fatty Acids to Provide Energy? - Reflections on Disadvantages of the Use of Free Fatty Acids as Fuel for Brain
- (2013) Peter Schönfeld et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- The APOE ε4/ε4 Genotype Potentiates Vascular Fibrin(Ogen) Deposition in Amyloid-Laden Vessels in the Brains of Alzheimer's Disease Patients
- (2013) Karin Hultman et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Amyloid- 1-42 Slows Clearance of Synaptically Released Glutamate by Mislocalizing Astrocytic GLT-1
- (2013) A. Scimemi et al. JOURNAL OF NEUROSCIENCE
- A Phase 3 Trial of Semagacestat for Treatment of Alzheimer's Disease
- (2013) Rachelle S. Doody et al. NEW ENGLAND JOURNAL OF MEDICINE
- Early Decline in Glucose Transport and Metabolism Precedes Shift to Ketogenic System in Female Aging and Alzheimer's Mouse Brain: Implication for Bioenergetic Intervention
- (2013) Fan Ding et al. PLoS One
- α7 Nicotinic Receptor-Mediated Astrocytic Gliotransmitter Release: Aβ Effects in a Preclinical Alzheimer’s Mouse Model
- (2013) Tiina Maria Pirttimaki et al. PLoS One
- A induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss
- (2013) M. Talantova et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sleep Drives Metabolite Clearance from the Adult Brain
- (2013) L. Xie et al. SCIENCE
- Polysomnographic and Subjective Sleep Markers of Mild Cognitive Impairment
- (2013) Eva Hita-Yañez et al. SLEEP
- Genes Involved in the Astrocyte-Neuron Lactate Shuttle (ANLS) Are Specifically Regulated in Cortical Astrocytes Following Sleep Deprivation in Mice
- (2013) Jean-Marie Petit et al. SLEEP
- Targeting norepinephrine in mild cognitive impairment and Alzheimer's disease
- (2013) Termpanit Chalermpalanupap et al. Alzheimers Research & Therapy
- The Complement System: An Unexpected Role in Synaptic Pruning During Development and Disease
- (2012) Alexander H. Stephan et al. Annual Review of Neuroscience
- Prevalence of Sleep Disturbances in Mild Cognitive Impairment and Dementing Disorders: A Multicenter Italian Clinical Cross-Sectional Study on 431 Patients
- (2012) B. Guarnieri et al. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
- Attenuating astrocyte activation accelerates plaque pathogenesis in APP/PS1 mice
- (2012) Andrew W. Kraft et al. FASEB JOURNAL
- Updated Energy Budgets for Neural Computation in the Neocortex and Cerebellum
- (2012) Clare Howarth et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Pathophysiology of the Neurovascular Unit: Disease Cause or Consequence?
- (2012) Danica B Stanimirovic et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Sleep/wake dependent changes in cortical glucose concentrations
- (2012) Michael B Dash et al. JOURNAL OF NEUROCHEMISTRY
- The chemokine, macrophage inflammatory protein-2γ, reduces the expression of glutamate transporter-1 on astrocytes and increases neuronal sensitivity to glutamate excitotoxicity
- (2012) Jie Fang et al. Journal of Neuroinflammation
- Early Stage Drug Treatment That Normalizes Proinflammatory Cytokine Production Attenuates Synaptic Dysfunction in a Mouse Model That Exhibits Age-Dependent Progression of Alzheimer's Disease-Related Pathology
- (2012) A. D. Bachstetter et al. JOURNAL OF NEUROSCIENCE
- Targeting Astrocytes Ameliorates Neurologic Changes in a Mouse Model of Alzheimer's Disease
- (2012) J. L. Furman et al. JOURNAL OF NEUROSCIENCE
- Genomic Analysis of Reactive Astrogliosis
- (2012) J. L. Zamanian et al. JOURNAL OF NEUROSCIENCE
- Evidence for Astrocytosis in Prodromal Alzheimer Disease Provided by 11C-Deuterium-L-Deprenyl: A Multitracer PET Paradigm Combining 11C-Pittsburgh Compound B and 18F-FDG
- (2012) S. F. Carter et al. JOURNAL OF NUCLEAR MEDICINE
- Apolipoprotein E controls cerebrovascular integrity via cyclophilin A
- (2012) Robert D. Bell et al. NATURE
- Neuroinflammation and Blood-Brain Barrier Changes in Capillary Amyloid Angiopathy
- (2012) Anna Carrano et al. Neurodegenerative Diseases
- Synaptic Energy Use and Supply
- (2012) Julia J. Harris et al. NEURON
- Synaptic changes in Alzheimer’s disease and its models
- (2012) J. Pozueta et al. NEUROSCIENCE
- Inhibition of Soluble Tumor Necrosis Factor Ameliorates Synaptic Alterations and Ca2+ Dysregulation in Aged Rats
- (2012) Diana M. Sama et al. PLoS One
- A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid
- (2012) J. J. Iliff et al. Science Translational Medicine
- Disruption of the Sleep-Wake Cycle and Diurnal Fluctuation of -Amyloid in Mice with Alzheimer's Disease Pathology
- (2012) J. H. Roh et al. Science Translational Medicine
- Vascular β-amyloid and early astrocyte alterations impair cerebrovascular function and cerebral metabolism in transgenic arcAβ mice
- (2011) Mario Merlini et al. ACTA NEUROPATHOLOGICA
- Mild cognitive impairment: pathology and mechanisms
- (2011) Elliott J. Mufson et al. ACTA NEUROPATHOLOGICA
- Glial molecular alterations with mouse brain development and aging: up-regulation of the Kir4.1 and aquaporin-4
- (2011) Rajaneesh Kumar Gupta et al. AGE
- Cerebral amyloid angiopathy in the elderly
- (2011) Anand Viswanathan et al. ANNALS OF NEUROLOGY
- Evidence for a role of dystroglycan regulating the membrane architecture of astroglial endfeet
- (2011) Susan Noell et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Cerebral glucose and lactate consumption during cerebral activation by physical activity in humans
- (2011) Peter Rasmussen et al. FASEB JOURNAL
- FOXO3a inhibits TNF-α- and IL-1β-induced astrocyte proliferation:Implication for reactive astrogliosis
- (2011) Min Cui et al. GLIA
- Impact of aquaporin-4 channels on K+ buffering and gap junction coupling in the hippocampus
- (2011) Susan Strohschein et al. GLIA
- Glial glutamate transporters: New actors in brain signaling
- (2011) Esther López-Bayghen et al. IUBMB LIFE
- Contribution of complement activation pathways to neuropathology differs among mouse models of Alzheimer's disease
- (2011) Maria I Fonseca et al. Journal of Neuroinflammation
- Astrocytes Control Glutamate Receptor Levels at Developing Synapses through SPARC- -Integrin Interactions
- (2011) E. V. Jones et al. JOURNAL OF NEUROSCIENCE
- Neuron-Specific Effects of Interleukin-1 Are Mediated by a Novel Isoform of the IL-1 Receptor Accessory Protein
- (2011) Y. Huang et al. JOURNAL OF NEUROSCIENCE
- In Vivo Evidence for Lactate as a Neuronal Energy Source
- (2011) M. T. Wyss et al. JOURNAL OF NEUROSCIENCE
- Regulation of the phosphatase calcineurin by insulin-like growth factor I unveils a key role of astrocytes in Alzheimer's pathology
- (2011) A M Fernandez et al. MOLECULAR PSYCHIATRY
- Central nervous system pericytes in health and disease
- (2011) Ethan A Winkler et al. NATURE NEUROSCIENCE
- Neuronal activity regulates the regional vulnerability to amyloid-β deposition
- (2011) Adam W Bero et al. NATURE NEUROSCIENCE
- Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
- (2011) Berislav V. Zlokovic NATURE REVIEWS NEUROSCIENCE
- Control of excitatory CNS synaptogenesis by astrocyte-secreted proteins Hevin and SPARC
- (2011) Hakan Kucukdereli et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Synthetic gelatinases inhibitor attenuates electromagnetic pulse-induced blood–brain barrier disruption by inhibiting gelatinases-mediated ZO-1 degradation in rats
- (2011) Lian-Bo Qiu et al. TOXICOLOGY
- Amyloid imaging in the differential diagnosis of dementia: review and potential clinical applications
- (2011) Robert Laforce et al. Alzheimers Research & Therapy
- Spines, Plasticity, and Cognition in Alzheimer's Model Mice
- (2011) Tara Spires-Jones et al. NEURAL PLASTICITY
- Proteolysis of calcineurin is increased in human hippocampus during mild cognitive impairment and is stimulated by oligomeric Abeta in primary cell culture
- (2010) Hafiz Mohmmad Abdul et al. AGING CELL
- Decline in mitochondrial bioenergetics and shift to ketogenic profile in brain during reproductive senescence
- (2010) Jia Yao et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Changes with Age in the Activities of β-Secretase and the Aβ-Degrading Enzymes Neprilysin, Insulin-Degrading Enzyme and Angiotensin-Converting Enzyme
- (2010) J. Scott Miners et al. BRAIN PATHOLOGY
- Potassium Channels and Neurovascular Coupling
- (2010) Kathryn M. Dunn et al. CIRCULATION JOURNAL
- Response of transcription factor NFATc3 to excitotoxic and traumatic brain insults: Identification of a subpopulation of reactive astrocytes
- (2010) María C. Serrano-Pérez et al. GLIA
- Homocysteine is associated with hippocampal and white matter atrophy in older subjects with mild hypertension
- (2010) Michael J. Firbank et al. INTERNATIONAL PSYCHOGERIATRICS
- Predominant Enhancement of Glucose Uptake in Astrocytes versus Neurons during Activation of the Somatosensory Cortex
- (2010) J. Chuquet et al. JOURNAL OF NEUROSCIENCE
- Norepinephrine Promotes Microglia to Uptake and Degrade Amyloid Peptide through Upregulation of Mouse Formyl Peptide Receptor 2 and Induction of Insulin-Degrading Enzyme
- (2010) Y. Kong et al. JOURNAL OF NEUROSCIENCE
- Amyloid Induces the Morphological Neurodegenerative Triad of Spine Loss, Dendritic Simplification, and Neuritic Dystrophies through Calcineurin Activation
- (2010) H.-Y. Wu et al. JOURNAL OF NEUROSCIENCE
- Amyloid- Aggregates Cause Alterations of Astrocytic Metabolic Phenotype: Impact on Neuronal Viability
- (2010) I. Allaman et al. JOURNAL OF NEUROSCIENCE
- TNF-α potentiates glutamate-induced spinal cord motoneuron death via NF-κB
- (2010) Laia Tolosa et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Pericytes regulate the blood–brain barrier
- (2010) Annika Armulik et al. NATURE
- Brain fuel metabolism, aging, and Alzheimer’s disease
- (2010) Stephen Cunnane et al. NUTRITION
- A Role for Thrombospondin-1 Deficits in Astrocyte-Mediated Spine and Synaptic Pathology in Down's Syndrome
- (2010) Octavio Garcia et al. PLoS One
- Astrocytic endfoot Ca2+ and BK channels determine both arteriolar dilation and constriction
- (2010) Hélène Girouard et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Spatial correlation between brain aerobic glycolysis and amyloid-β (Aβ) deposition
- (2010) Andrei G. Vlassenko et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Decreased Clearance of CNS -Amyloid in Alzheimer's Disease
- (2010) K. G. Mawuenyega et al. SCIENCE
- Where Vascular Meets Neurodegenerative Disease
- (2010) J. A. Schneider et al. STROKE
- Alterations of matrix metalloproteinases in the healthy elderly with increased risk of prodromal Alzheimer's disease
- (2010) Erik Stomrud et al. Alzheimers Research & Therapy
- Blood Lactate is an Important Energy Source for the Human Brain
- (2009) Gerrit van Hall et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Long-Term Homeostasis of Extracellular Glutamate in the Rat Cerebral Cortex across Sleep and Waking States
- (2009) M. B. Dash et al. JOURNAL OF NEUROSCIENCE
- Cognitive Decline in Alzheimer's Disease Is Associated with Selective Changes in Calcineurin/NFAT Signaling
- (2009) H. M. Abdul et al. JOURNAL OF NEUROSCIENCE
- Uniquely Hominid Features of Adult Human Astrocytes
- (2009) N. A. Oberheim et al. JOURNAL OF NEUROSCIENCE
- Vascular amyloid alters astrocytic water and potassium channels in mouse models and humans with Alzheimer's disease
- (2009) D.M. Wilcock et al. NEUROSCIENCE
- Amyloid- Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle
- (2009) J.-E. Kang et al. SCIENCE
- Cyclooxygenase-2 inhibition improves amyloid-β-mediated suppression of memory and synaptic plasticity
- (2008) Linda A. Kotilinek et al. BRAIN
- Advances in measuring cellular bioenergetics using extracellular flux
- (2008) David A. Ferrick et al. DRUG DISCOVERY TODAY
- Interleukin-1β-dependent Signaling between Astrocytes and Neurons Depends Critically on Astrocytic Calcineurin/NFAT Activity
- (2008) Michelle A. Sama et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The inflammatory cytokine, interleukin-1 beta, mediates loss of astroglial glutamate transport and drives excitotoxic motor neuron injury in the spinal cord during acute viral encephalomyelitis
- (2008) Natalie A. Prow et al. JOURNAL OF NEUROCHEMISTRY
- Proteomics-Determined Differences in the Concanavalin-A-Fractionated Proteome of Hippocampus and Inferior Parietal Lobule in Subjects with Alzheimer’s Disease and Mild Cognitive Impairment: Implications for Progression of AD
- (2008) Joshua B. Owen et al. JOURNAL OF PROTEOME RESEARCH
- Brain metabolism dictates the polarity of astrocyte control over arterioles
- (2008) Grant R. J. Gordon et al. NATURE
- Astrocyte phenotype in relation to Alzheimer-type pathology in the ageing brain
- (2008) J.E. Simpson et al. NEUROBIOLOGY OF AGING
- A new blood–brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes
- (2008) Shinsuke Nakagawa et al. NEUROCHEMISTRY INTERNATIONAL
- Hippocampal hypometabolism predicts cognitive decline from normal aging
- (2007) Lisa Mosconi et al. NEUROBIOLOGY OF AGING
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