Diverging longitudinal changes in astrocytosis and amyloid PET in autosomal dominant Alzheimer’s disease

Increased Cortical Thickness and Caudate Volume Precede Atrophy in PSEN1 Mutation Carriers

(2017) Juan Fortea et al.   JOURNAL OF ALZHEIMERS DISEASE

Astrocytes in physiological aging and Alzheimer’s disease

(2016) J.J. Rodríguez-Arellano et al.   NEUROSCIENCE

Imaging neuroinflammation in Alzheimer's disease and other dementias: Recent advances and future directions

(2015) James Varley et al.   Alzheimers & Dementia

Astrocytosis precedes amyloid plaque deposition in Alzheimer APPswe transgenic mouse brain: a correlative positron emission tomography and in vitro imaging study

(2015) Elena Rodriguez-Vieitez et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Longitudinal assessment of neuroimaging and clinical markers in autosomal dominant Alzheimer's disease: a prospective cohort study

(2015) Wai-Ying Wendy Yau et al.   LANCET NEUROLOGY

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Innate immunity in Alzheimer's disease

(2015) Michael T Heneka et al.   NATURE IMMUNOLOGY

Evolving brain structural changes in PSEN1 mutation carriers

(2015) Roser Sala-Llonch et al.   NEUROBIOLOGY OF AGING

Early astrocytosis in autosomal dominant Alzheimer’s disease measured in vivo by multi-tracer positron emission tomography

(2015) Michael Schöll et al.   Scientific Reports

Brain Imaging and Blood Biomarker Abnormalities in Children With Autosomal Dominant Alzheimer Disease

(2015) Yakeel T. Quiroz et al.   JAMA Neurology

Associations Between Biomarkers and Age in the Presenilin 1 E280A Autosomal Dominant Alzheimer Disease Kindred

(2015) Adam S. Fleisher et al.   JAMA Neurology

Regional distribution of synaptic markers and APP correlate with distinct clinicopathological features in sporadic and familial Alzheimer’s disease

(2014) Mitsuru Shinohara et al.   BRAIN

Genetic Heterogeneity in Alzheimer Disease and Implications for Treatment Strategies

(2014) John M. Ringman et al.   Current Neurology and Neuroscience Reports

Astrocytosis measured by 11C-deprenyl PET correlates with decrease in gray matter density in the parahippocampus of prodromal Alzheimer’s patients

(2014) IL Han Choo et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Tracking neuroinflammation in Alzheimer’s disease: the role of positron emission tomography imaging

(2014) Eduardo Zimmer et al.   Journal of Neuroinflammation

Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria

(2014) Bruno Dubois et al.   LANCET NEUROLOGY

Symptom onset in autosomal dominant Alzheimer disease: A systematic review and meta-analysis

(2014) D. C. Ryman et al.   NEUROLOGY

Glial Asthenia and Functional Paralysis

(2014) Alexei Verkhratsky et al.   NEUROSCIENTIST

The Value of Biomarker Comparisons Between Autosomal Dominant and Late-Onset Alzheimer Disease

(2014) Adam S. Fleisher   JAMA Neurology

Functional Connectivity in Autosomal Dominant and Late-Onset Alzheimer Disease

(2014) Jewell B. Thomas et al.   JAMA Neurology

Reply: Implications of presymptomatic change in thalamus and caudate in Alzheimer’s disease

(2013) Natalie S. Ryan et al.   BRAIN

Magnetic resonance imaging evidence for presymptomatic change in thalamus and caudate in familial Alzheimer’s disease

(2013) Natalie S. Ryan et al.   BRAIN

3H-Deprenyl and 3H-PIB autoradiography show different laminar distributions of astroglia and fibrillar β-amyloid in Alzheimer brain

(2013) Amelia Marutle et al.   Journal of Neuroinflammation

Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study

(2013) Victor L Villemagne et al.   LANCET NEUROLOGY

Aβ-independent processes—rethinking preclinical AD

(2013) Gaël Chételat   Nature Reviews Neurology

Biomarker Modeling of Alzheimer’s Disease

(2013) Clifford R. Jack et al.   NEURON

Heterogeneity of reactive astrocytes

(2013) Mark A. Anderson et al.   NEUROSCIENCE LETTERS

Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease

(2013) T. L. S. Benzinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterizing the normative profile of 18F-FDG PET brain imaging: Sex difference, aging effect, and cognitive reserve

(2013) Hiroshi Yoshizawa et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

Increased in Vivo Amyloid- 42 Production, Exchange, and Loss in Presenilin Mutation Carriers

(2013) R. Potter et al.   Science Translational Medicine

A European multicentre PET study of fibrillar amyloid in Alzheimer’s disease

(2012) Agneta Nordberg et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

The role of astrocytes in amyloid β-protein toxicity and clearance

(2012) Dietmar Rudolf Thal   EXPERIMENTAL NEUROLOGY

Noninvasive Molecular Imaging of Neuroinflammation

(2012) Andreas H Jacobs et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Region-Specific Hierarchy between Atrophy, Hypometabolism, and  -Amyloid (A ) Load in Alzheimer's Disease Dementia

(2012) R. La Joie et al.   JOURNAL OF NEUROSCIENCE

Targeting Astrocytes Ameliorates Neurologic Changes in a Mouse Model of Alzheimer's Disease

(2012) J. L. Furman et al.   JOURNAL OF NEUROSCIENCE

Evidence for Astrocytosis in Prodromal Alzheimer Disease Provided by 11C-Deuterium-L-Deprenyl: A Multitracer PET Paradigm Combining 11C-Pittsburgh Compound B and 18F-FDG

(2012) S. F. Carter et al.   JOURNAL OF NUCLEAR MEDICINE

Florbetapir PET analysis of amyloid-β deposition in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional study

(2012) Adam S Fleisher et al.   LANCET NEUROLOGY

Low PiB PET retention in presence of pathologic CSF biomarkers in Arctic APP mutation carriers

(2012) M. Scholl et al.   NEUROLOGY

Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease

(2012) Randall J. Bateman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Amyloid-Dependent and Amyloid-Independent Stages of Alzheimer Disease

(2011) Bradley T. Hyman   ARCHIVES OF NEUROLOGY

In vivo imaging of astrocytosis in Alzheimer’s disease: an 11C-L-deuteriodeprenyl and PIB PET study

(2011) Alexander Frizell Santillo et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

The effect of amyloid associated proteins on the expression of genes involved in amyloid-β clearance by adult human astrocytes

(2011) Sandra D. Mulder et al.   EXPERIMENTAL NEUROLOGY

Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders

(2011) Berislav V. Zlokovic   NATURE REVIEWS NEUROSCIENCE

Alzheimer's Disease: The Challenge of the Second Century

(2011) D. M. Holtzman et al.   Science Translational Medicine

Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease

(2011) Randall J Bateman et al.   Alzheimers Research & Therapy

Positron emission tomography imaging and clinical progression in relation to molecular pathology in the first Pittsburgh Compound B positron emission tomography patient with Alzheimer’s disease

(2010) Ahmadul Kadir et al.   BRAIN

Astrocyte heterogeneity: an underappreciated topic in neurobiology

(2010) Ye Zhang et al.   CURRENT OPINION IN NEUROBIOLOGY

The PSEN1 I143T mutation in a Swedish family with Alzheimer's disease: clinical report and quantification of Aβ in different brain regions

(2010) Lina Keller et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Amyloid-  Aggregates Cause Alterations of Astrocytic Metabolic Phenotype: Impact on Neuronal Viability

(2010) I. Allaman et al.   JOURNAL OF NEUROSCIENCE

Activated MAO-B in the brain of Alzheimer patients, demonstrated by [11C]-l-deprenyl using whole hemisphere autoradiography

(2010) Balázs Gulyás et al.   NEUROCHEMISTRY INTERNATIONAL

High Striatal Amyloid β-Peptide Deposition Across Different Autosomal Alzheimer Disease Mutation Types

(2009) Victor L. Villemagne et al.   ARCHIVES OF NEUROLOGY

Activated astrocytes: a therapeutic target in Alzheimer’s disease?

(2009) Stacey Fuller et al.   Expert Review of Neurotherapeutics

Glucose metabolism and PIB binding in carriers of a His163Tyr presenilin 1 mutation

(2009) Michael Schöll et al.   NEUROBIOLOGY OF AGING

PET amyloid ligand [11C]PIB uptake shows predominantly striatal increase in variant Alzheimer's disease

(2008) J. Koivunen et al.   BRAIN

The Mystery and Magic of Glia: A Perspective on Their Roles in Health and Disease

(2008) Ben A. Barres   NEURON