Astrocytic metabolic and inflammatory changes as a function of age

Lipoic acid restores age-associated impairment of brain energy metabolism through the modulation of Akt/JNK signaling and PGC1α transcriptional pathway

(2013) Tianyi Jiang et al.   AGING CELL

Metabolic triad in brain aging: mitochondria, insulin/IGF-1 signalling and JNK signalling: Figure 1

(2013) Fei Yin et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH

(2013) Guo Zhang et al.   NATURE

A quantitative study of the cell-type specific modulation of c-Rel by hydrogen peroxide and TNF-α

(2013) Virgínia Oliveira-Marques et al.   Redox Biology

Transcriptional control of mitochondrial biogenesis and its interface with inflammatory processes

(2012) Claude A. Piantadosi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The inflammation highway: metabolism accelerates inflammatory traffic in obesity

(2012) Amy R. Johnson et al.   IMMUNOLOGICAL REVIEWS

JNK Expression by Macrophages Promotes Obesity-Induced Insulin Resistance and Inflammation

(2012) M. S. Han et al.   SCIENCE

Astrocyte-Neuron Lactate Transport Is Required for Long-Term Memory Formation

(2011) Akinobu Suzuki et al.   CELL

Constitutive intestinal NF-κB does not trigger destructive inflammation unless accompanied by MAPK activation

(2011) Monica Guma et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Role of nitric oxide-mediated glutathionylation in neuronal function: potential regulation of energy utilization

(2010) Li-Peng Yap et al.   BIOCHEMICAL JOURNAL

Neuron-glia metabolic coupling and plasticity

(2010) Pierre J. Magistretti   EXPERIMENTAL PHYSIOLOGY

Nitric oxide synthase-2 regulates mitochondrial Hsp60 chaperone function during bacterial peritonitis in mice

(2010) Hagir B. Suliman et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidants Positively or Negatively Regulate Nuclear Factor κB in a Context-dependent Manner

(2010) Noureddine Loukili et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

JNK: A Stress-Activated Protein Kinase Therapeutic Strategies and Involvement in Alzheimer’s and Various Neurodegenerative Abnormalities

(2010) Sidharth Mehan et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

NOX Enzymes in the Central Nervous System: From Signaling to Disease

(2009) Silvia Sorce et al.   ANTIOXIDANTS & REDOX SIGNALING

Inflammatory cytokines stimulate the chemokines CCL2/MCP-1 and CCL7/MCP-7 through NFκB and MAPK dependent pathways in rat astrocytes

(2009) Wendy L. Thompson et al.   BRAIN RESEARCH

Activation of c-Jun-N-terminal kinase and decline of mitochondrial pyruvate dehydrogenase activity during brain aging

(2009) Qiongqiong Zhou et al.   FEBS LETTERS

Altered Brain Mitochondrial Metabolism in Healthy Aging as Assessed by in vivo Magnetic Resonance Spectroscopy

(2009) Fawzi Boumezbeur et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Increased levels of proinflammatory cytokines in the aged rat brain attenuate injury-induced cytokine response after excitotoxic damage

(2009) O. Campuzano et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Glycolysis: a bioenergetic or a survival pathway?

(2009) Juan P. Bolaños et al.   TRENDS IN BIOCHEMICAL SCIENCES

Dysfunction of astrocytes in senescence-accelerated mice SAMP8 reduces their neuroprotective capacity

(2008) Silvia García-Matas et al.   AGING CELL