Disruption of the Sleep-Wake Cycle and Diurnal Fluctuation of  -Amyloid in Mice with Alzheimer's Disease Pathology

EEG, Activity, and Sleep Architecture in a Transgenic AβPPswe/PSEN1A246E Alzheimer's Disease Mouse

(2017) Amar Jyoti et al.   JOURNAL OF ALZHEIMERS DISEASE

Trafficking and Proteolytic Processing of APP

(2013) C. Haass et al.   Cold Spring Harbor Perspectives in Medicine

Bidirectional Relationship between Functional Connectivity and Amyloid-  Deposition in Mouse Brain

(2012) A. W. Bero et al.   JOURNAL OF NEUROSCIENCE

Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Reisa A. Sperling et al.   Alzheimers & Dementia

Circadian activity rhythms and risk of incident dementia and mild cognitive impairment in older women

(2011) Gregory J. Tranah et al.   ANNALS OF NEUROLOGY

Effects of Age and Amyloid Deposition on Aβ Dynamics in the Human Central Nervous System

(2011) Yafei Huang   ARCHIVES OF NEUROLOGY

Sleep-Disordered Breathing, Hypoxia, and Risk of Mild Cognitive Impairment and Dementia in Older Women

(2011) Kristine Yaffe et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Dynamic Analysis of Amyloid  -Protein in Behaving Mice Reveals Opposing Changes in ISF versus Parenchymal A  during Age-Related Plaque Formation

(2011) S. Hong et al.   JOURNAL OF NEUROSCIENCE

Local sleep in awake rats

(2011) Vladyslav V. Vyazovskiy et al.   NATURE

Neuronal activity regulates the regional vulnerability to amyloid-β deposition

(2011) Adam W Bero et al.   NATURE NEUROSCIENCE

Sleep and waking modulate spine turnover in the adolescent mouse cortex

(2011) Stephanie Maret et al.   NATURE NEUROSCIENCE

Hypocretin (orexin) loss in Alzheimer's disease

(2011) Rolf Fronczek et al.   NEUROBIOLOGY OF AGING

Inducing Sleep by Remote Control Facilitates Memory Consolidation in Drosophila

(2011) J. M. Donlea et al.   SCIENCE

Mapping the Road Forward in Alzheimer's Disease

(2011) D. M. Holtzman et al.   Science Translational Medicine

Alzheimer's Disease: The Challenge of the Second Century

(2011) D. M. Holtzman et al.   Science Translational Medicine

Update on Sleep and Its Disorders

(2010) Allan I. Pack et al.   Annual Review of Medicine

The benefits and limitations of animal models for translational research in neurodegenerative diseases

(2010) Mathias Jucker   NATURE MEDICINE

Amyloid Plaques Disrupt Resting State Default Mode Network Connectivity in Cognitively Normal Elderly

(2009) Yvette I. Sheline et al.   BIOLOGICAL PSYCHIATRY

Cerebrospinal fluid tau and ptau181increase with cortical amyloid deposition in cognitively normal individuals: Implications for future clinical trials of Alzheimer's disease

(2009) Anne M. Fagan et al.   EMBO Molecular Medicine

Characterizing the Appearance and Growth of Amyloid Plaques in APP/PS1 Mice

(2009) P. Yan et al.   JOURNAL OF NEUROSCIENCE

Overexpression of Low-Density Lipoprotein Receptor in the Brain Markedly Inhibits Amyloid Deposition and Increases Extracellular Aβ Clearance

(2009) Jungsu Kim et al.   NEURON

Amyloid Deposition Is Associated with Impaired Default Network Function in Older Persons without Dementia

(2009) Reisa A. Sperling et al.   NEURON

Amyloid-  Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle

(2009) J.-E. Kang et al.   SCIENCE

Synchronous Hyperactivity and Intercellular Calcium Waves in Astrocytes in Alzheimer Mice

(2009) K. V. Kuchibhotla et al.   SCIENCE

Animal models of Alzheimer's disease and frontotemporal dementia

(2008) Jürgen Götz et al.   NATURE REVIEWS NEUROSCIENCE

Lactate production and neurotransmitters; evidence from microdialysis studies

(2008) Takashi Uehara et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease

(2008) M. A. Busche et al.   SCIENCE