标题
Epigenetic regulation of epithelial–mesenchymal transition
作者
关键词
Epithelial–mesenchymal transition, Tumor progression, Epigenetics, Histone modifications, Transcription regulation
出版物
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 73, Issue 23, Pages 4493-4515
出版商
Springer Nature
发表日期
2016-07-08
DOI
10.1007/s00018-016-2303-1
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Enhanced Histone Deacetylase Activity in Malignant Melanoma Provokes RAD51 and FANCD2-Triggered Drug Resistance
- (2016) A. Krumm et al. CANCER RESEARCH
- Mechanisms of long noncoding RNA function in development and disease
- (2016) Sandra U. Schmitz et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- From junk to master regulators of invasion: lncRNA functions in migration, EMT and metastasis
- (2016) Sonam Dhamija et al. INTERNATIONAL JOURNAL OF CANCER
- Epigenetic regulation of E-cadherin expression by the histone demethylase UTX in colon cancer cells
- (2016) Lin Zha et al. MEDICAL ONCOLOGY
- A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1
- (2016) Jacob I Stuckey et al. Nature Chemical Biology
- Screen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance
- (2016) Molly Gale et al. Oncotarget
- HDAC1 promoted migration and invasion binding with TCF12 by promoting EMT progress in gallbladder cancer
- (2016) Junyi He et al. Oncotarget
- Setdb1, a novel interactor of ΔNp63, is involved in breast tumorigenesis
- (2016) Carla Regina et al. Oncotarget
- The dual function of PRMT1 in modulating epithelial-mesenchymal transition and cellular senescence in breast cancer cells through regulation of ZEB1
- (2016) Yanyan Gao et al. Scientific Reports
- MicroRNA Regulation of Epithelial to Mesenchymal Transition
- (2016) Mohammed Abba et al. Journal of Clinical Medicine
- DNMT1 and EZH2 mediated methylation silences the microRNA-200b/a/429 gene and promotes tumor progression
- (2015) Xianghong Ning et al. CANCER LETTERS
- TWIST1-Induced miR-424 Reversibly Drives Mesenchymal Programming while Inhibiting Tumor Initiation
- (2015) D. J. Drasin et al. CANCER RESEARCH
- ZEB1-associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat
- (2015) S. Meidhof et al. EMBO Molecular Medicine
- MPP8 and SIRT1 crosstalk in E-cadherin gene silencing and epithelial-mesenchymal transition
- (2015) L. Sun et al. EMBO REPORTS
- UTX inhibits EMT-induced breast CSC properties by epigenetic repression of EMT genes in cooperation with LSD1 and HDAC1
- (2015) H.-J. Choi et al. EMBO REPORTS
- SUV420H2 suppresses breast cancer cell invasion through down regulation of the SH2 domain-containing focal adhesion protein tensin-3
- (2015) Yoshimi Shinchi et al. EXPERIMENTAL CELL RESEARCH
- Brg1 promotes both tumor-suppressive and oncogenic activities at distinct stages of pancreatic cancer formation
- (2015) Nilotpal Roy et al. GENES & DEVELOPMENT
- BRD4 Inhibitor Inhibits Colorectal Cancer Growth and Metastasis
- (2015) Yuan Hu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Long Non-coding RNAs (LncRNA) Regulated by Transforming Growth Factor (TGF) β
- (2015) Edward J. Richards et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SET8 induces epithelial-mesenchymal transition and enhances prostate cancer cell metastasis by cooperating with ZEB1
- (2015) LIEJUN HOU et al. Molecular Medicine Reports
- Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
- (2015) Xiaofeng Zheng et al. NATURE
- Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance
- (2015) Kari R. Fischer et al. NATURE
- Sound of silence: the properties and functions of repressive Lys methyltransferases
- (2015) Chiara Mozzetta et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Epithelial–Mesenchymal Plasticity: A Central Regulator of Cancer Progression
- (2015) Xin Ye et al. TRENDS IN CELL BIOLOGY
- SUZ12 promotes gastric cancer cell proliferation and metastasis by regulating KLF2 and E-cadherin
- (2015) Rui Xia et al. TUMOR BIOLOGY
- DOT1L cooperates with the c-Myc-p300 complex to epigenetically derepress CDH1 transcription factors in breast cancer progression
- (2015) Min-Hyung Cho et al. Nature Communications
- Histone methyltransferase SETDB1 regulates liver cancer cell growth through methylation of p53
- (2015) Qi Fei et al. Nature Communications
- Targeting the SIN3A-PF1 interaction inhibits epithelial to mesenchymal transition and maintenance of a stem cell phenotype in triple negative breast cancer
- (2015) Nidhi Bansal et al. Oncotarget
- Histone demethylase RBP2 promotes malignant progression of gastric cancer through TGF-β1-(p-Smad3)-RBP2-E-cadherin-Smad3 feedback circuit
- (2015) Xiuming Liang et al. Oncotarget
- JARID1B promotes metastasis and epithelial-mesenchymal transition via PTEN/AKT signaling in hepatocellular carcinoma cells
- (2015) Bo Tang et al. Oncotarget
- Kaiso, a transcriptional repressor, promotes cell migration and invasion of prostate cancer cells through regulation of miR-31 expression
- (2015) Honghe Wang et al. Oncotarget
- Snail and Slug collaborate on EMT and tumor metastasis through miR-101-mediated EZH2 axis in oral tongue squamous cell carcinoma
- (2015) Min Zheng et al. Oncotarget
- G9a is essential for EMT-mediated metastasis and maintenance of cancer stem cell-like characters in head and neck squamous cell carcinoma
- (2015) Shuli Liu et al. Oncotarget
- G9a orchestrates PCL3 and KDM7A to promote histone H3K27 methylation
- (2015) Mei-Ren Pan et al. Scientific Reports
- Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics
- (2015) C. Kadoch et al. Science Advances
- The histone demethylase JMJD1A induces cell migration and invasion by up-regulating the expression of the long noncoding RNA MALAT1
- (2015) Andrew E. Tee et al. Oncotarget
- Inhibition of histone H3K79 methylation selectively inhibits proliferation, self-renewal and metastatic potential of breast cancer
- (2015) Li Zhang et al. Oncotarget
- Disrupting the Interaction of BRD4 with Diacetylated Twist Suppresses Tumorigenesis in Basal-like Breast Cancer
- (2014) Jian Shi et al. CANCER CELL
- H3K9 Histone Methyltransferase, KMT1E/SETDB1, Cooperates with the SMAD2/3 Pathway to Suppress Lung Cancer Metastasis
- (2014) P.-C. Wu et al. CANCER RESEARCH
- A Comprehensive DNA Methylation Profile of Epithelial-to-Mesenchymal Transition
- (2014) F. J. Carmona et al. CANCER RESEARCH
- PRMT7 Induces Epithelial-to-Mesenchymal Transition and Promotes Metastasis in Breast Cancer
- (2014) R. Yao et al. CANCER RESEARCH
- UTX and MLL4 Coordinately Regulate Transcriptional Programs for Cell Proliferation and Invasiveness in Breast Cancer Cells
- (2014) Jae-Hwan Kim et al. CANCER RESEARCH
- Small Molecule Control of Chromatin Remodeling
- (2014) Aidan Finley et al. CHEMISTRY & BIOLOGY
- Mind the Methyl: Methyllysine Binding Proteins in Epigenetic Regulation
- (2014) Tobias Wagner et al. ChemMedChem
- Nuclear localization of Kaiso promotes the poorly differentiated phenotype and EMT in infiltrating ductal carcinomas
- (2014) Jacqueline Jones et al. CLINICAL & EXPERIMENTAL METASTASIS
- Expression of PRMT5 in lung adenocarcinoma and its significance in epithelial-mesenchymal transition
- (2014) Reem Ibrahim et al. HUMAN PATHOLOGY
- New and emerging HDAC inhibitors for cancer treatment
- (2014) Alison C. West et al. JOURNAL OF CLINICAL INVESTIGATION
- The Mechanisms behind the Therapeutic Activity of BET Bromodomain Inhibition
- (2014) Junwei Shi et al. MOLECULAR CELL
- The high mobility group A2 protein epigenetically silences the Cdh1 gene during epithelial-to-mesenchymal transition
- (2014) E-Jean Tan et al. NUCLEIC ACIDS RESEARCH
- MiR-7, Inhibited Indirectly by LincRNA HOTAIR, Directly Inhibits SETDB1 and Reverses the EMT of Breast Cancer Stem Cells by Downregulating the STAT3 Pathway
- (2014) Hongyi Zhang et al. STEM CELLS
- A Brief History of Epigenetics
- (2014) G. Felsenfeld Cold Spring Harbor Perspectives in Biology
- LincRNA-ROR induces epithelial-to-mesenchymal transition and contributes to breast cancer tumorigenesis and metastasis
- (2014) P Hou et al. Cell Death & Disease
- Histone Demethylase RBP2 Is Critical for Breast Cancer Progression and Metastasis
- (2014) Jian Cao et al. Cell Reports
- δEF1 associates with DNMT1 and maintains DNA methylation of the E-cadherin promoter in breast cancer cells
- (2014) Akihiko Fukagawa et al. Cancer Medicine
- The role of chromatin modifiers in normal and malignant hematopoiesis
- (2013) J. S. Butler et al. BLOOD
- Histone deacetylase inhibitor entinostat reverses epithelial to mesenchymal transition of breast cancer cells by reversing the repression of E-cadherin
- (2013) Preeti Shah et al. BREAST CANCER RESEARCH AND TREATMENT
- Histone Demethylase RBP2 Promotes Lung Tumorigenesis and Cancer Metastasis
- (2013) Y.-C. Teng et al. CANCER RESEARCH
- Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers
- (2013) Jakob Lovén et al. CELL
- Poised Chromatin at the ZEB1 Promoter Enables Breast Cancer Cell Plasticity and Enhances Tumorigenicity
- (2013) Christine L. Chaffer et al. CELL
- KDM5B histone demethylase controls epithelial-mesenchymal transition of cancer cells by regulating the expression of the microRNA-200 family
- (2013) Zanabazar Enkhbaatar et al. CELL CYCLE
- JMJD2B Promotes Epithelial-Mesenchymal Transition by Cooperating with -Catenin and Enhances Gastric Cancer Metastasis
- (2013) L. Zhao et al. CLINICAL CANCER RESEARCH
- Identification of a long non-coding RNA-associated RNP complex regulating metastasis at the translational step
- (2013) Kiranmai Gumireddy et al. EMBO JOURNAL
- Kindlin 2 promotes breast cancer invasion via epigenetic silencing of the microRNA200 gene family
- (2013) Yu Yu et al. INTERNATIONAL JOURNAL OF CANCER
- The Malignant Brain Tumor (MBT) Domain Protein SFMBT1 Is an Integral Histone Reader Subunit of the LSD1 Demethylase Complex for Chromatin Association and Epithelial-to-mesenchymal Transition
- (2013) Ming Tang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SWI/SNF Chromatin-Remodeling Factor Smarcd3/Baf60c Controls Epithelial-Mesenchymal Transition by Inducing Wnt5a Signaling
- (2013) N. V. Jordan et al. MOLECULAR AND CELLULAR BIOLOGY
- A General Molecular Affinity Strategy for Global Detection and Proteomic Analysis of Lysine Methylation
- (2013) Kaitlyn E. Moore et al. MOLECULAR CELL
- TET enzymes, TDG and the dynamics of DNA demethylation
- (2013) Rahul M. Kohli et al. NATURE
- Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain
- (2013) Lindsey I James et al. Nature Chemical Biology
- The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF complex
- (2013) John R Prensner et al. NATURE GENETICS
- The epigenetics of epithelial-mesenchymal plasticity in cancer
- (2013) Wai Leong Tam et al. NATURE MEDICINE
- Histone lysine demethylases as targets for anticancer therapy
- (2013) Jonas W. Højfeldt et al. NATURE REVIEWS DRUG DISCOVERY
- Transcriptional regulation by Polycomb group proteins
- (2013) Luciano Di Croce et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- DNA methylation dynamics in health and disease
- (2013) Yehudit Bergman et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis
- (2013) M Rodriguez-Paredes et al. ONCOGENE
- Multilayer control of the EMT master regulators
- (2013) H Zheng et al. ONCOGENE
- A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth
- (2013) Lei Wang et al. Nature Communications
- Architecture of epigenetic reprogramming following Twist1-mediated epithelial-mesenchymal transition
- (2013) Gabriel G Malouf et al. GENOME BIOLOGY
- The mutational landscape of chromatin regulatory factors across 4,623 tumor samples
- (2013) Abel Gonzalez-Perez et al. GENOME BIOLOGY
- Global Decrease of Histone H3K27 Acetylation in ZEB1-Induced Epithelial to Mesenchymal Transition in Lung Cancer Cells
- (2013) Joëlle Roche et al. Cancers
- Nuclear Kaiso Indicates Aggressive Prostate Cancers and Promotes Migration and Invasiveness of Prostate Cancer Cells
- (2012) Jacqueline Jones et al. AMERICAN JOURNAL OF PATHOLOGY
- Programming of DNA Methylation Patterns
- (2012) Howard Cedar et al. Annual Review of Biochemistry
- Histone deacetylase inhibitor induction of epithelial–mesenchymal transitions via up-regulation of Snail facilitates cancer progression
- (2012) Guan-Min Jiang et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Inhibiting Interactions of Lysine Demethylase LSD1 with Snail/Slug Blocks Cancer Cell Invasion
- (2012) G. Ferrari-Amorotti et al. CANCER RESEARCH
- Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family
- (2012) Panagis Filippakopoulos et al. CELL
- Cancer epigenomics: beyond genomics
- (2012) Juan Sandoval et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Trans-tail regulation of MLL4-catalyzed H3K4 methylation by H4R3 symmetric dimethylation is mediated by a tandem PHD of MLL4
- (2012) S. S. Dhar et al. GENES & DEVELOPMENT
- Histone Demethylase KDM6B Promotes Epithelial-Mesenchymal Transition
- (2012) Sivakumar Ramadoss et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Interactions Between β-Catenin and Transforming Growth Factor-β Signaling Pathways Mediate Epithelial-Mesenchymal Transition and Are Dependent on the Transcriptional Co-activator cAMP-response Element-binding Protein (CREB)-binding Protein (CBP)
- (2012) Beiyun Zhou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A PHD12–Snail2 repressive complex epigenetically mediates neural crest epithelial-to-mesenchymal transition
- (2012) Pablo H. Strobl-Mazzulla et al. JOURNAL OF CELL BIOLOGY
- G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer
- (2012) Chenfang Dong et al. JOURNAL OF CLINICAL INVESTIGATION
- Histone Recognition by Human Malignant Brain Tumor Domains
- (2012) Nataliya Nady et al. JOURNAL OF MOLECULAR BIOLOGY
- SIRT1 induces EMT by cooperating with EMT transcription factors and enhances prostate cancer cell migration and metastasis
- (2012) V Byles et al. ONCOGENE
- Interaction with Suv39H1 is critical for Snail-mediated E-cadherin repression in breast cancer
- (2012) C Dong et al. ONCOGENE
- Mutant p53 gain-of-function induces epithelial–mesenchymal transition through modulation of the miR-130b–ZEB1 axis
- (2012) P Dong et al. ONCOGENE
- Cooperation of p300 and PCAF in the Control of MicroRNA 200c/141 Transcription and Epithelial Characteristics
- (2012) Yoshiaki Mizuguchi et al. PLoS One
- Over-Expression of LSD1 Promotes Proliferation, Migration and Invasion in Non-Small Cell Lung Cancer
- (2012) Tangfeng Lv et al. PLoS One
- Histone Deacetylase Inhibitors Induce Epithelial-to-Mesenchymal Transition in Prostate Cancer Cells
- (2012) Dejuan Kong et al. PLoS One
- PRC2/EED-EZH2 Complex Is Up-Regulated in Breast Cancer Lymph Node Metastasis Compared to Primary Tumor and Correlates with Tumor Proliferation In Situ
- (2012) Hongxiang Yu et al. PLoS One
- The Ins and Outs of the Epithelial to Mesenchymal Transition in Health and Disease
- (2011) M. Angela Nieto Annual Review of Cell and Developmental Biology
- Binding of the JmjC Demethylase JARID1B to LSD1/NuRD Suppresses Angiogenesis and Metastasis in Breast Cancer Cells by Repressing Chemokine CCL14
- (2011) Q. Li et al. CANCER RESEARCH
- Snail2 is an Essential Mediator of Twist1-Induced Epithelial Mesenchymal Transition and Metastasis
- (2011) E. Casas et al. CANCER RESEARCH
- BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc
- (2011) Jake E. Delmore et al. CELL
- MicroRNAs as regulators of epithelial-mesenchymal transition
- (2011) Philip A. Gregory et al. CELL CYCLE
- SET8 promotes epithelial-mesenchymal transition and confers TWIST dual transcriptional activities
- (2011) Fen Yang et al. EMBO JOURNAL
- Recruitment of histone deacetylases HDAC1 and HDAC2 by the transcriptional repressor ZEB1 downregulates E-cadherin expression in pancreatic cancer
- (2011) Ali Aghdassi et al. GUT
- miR-200a Regulates SIRT1 Expression and Epithelial to Mesenchymal Transition (EMT)-like Transformation in Mammary Epithelial Cells
- (2011) Gabriel Eades et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Functional Cooperation between Snail1 and Twist in the Regulation ofZEB1Expression during Epithelial to Mesenchymal Transition
- (2011) Natàlia Dave et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial–mesenchymal transition
- (2011) Nam Hee Kim et al. JOURNAL OF CELL BIOLOGY
- p53 regulates epithelial–mesenchymal transition through microRNAs targeting ZEB1 and ZEB2
- (2011) Taewan Kim et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Structural Insights for MPP8 Chromodomain Interaction with Histone H3 Lysine 9: Potential Effect of Phosphorylation on Methyl-Lysine Binding
- (2011) Yanqi Chang et al. JOURNAL OF MOLECULAR BIOLOGY
- Targeted Inhibition of -Catenin/CBP Signaling Ameliorates Renal Interstitial Fibrosis
- (2011) S. Hao et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- SUV420H2-Mediated H4K20 Trimethylation Enforces RNA Polymerase II Promoter-Proximal Pausing by Blocking hMOF-Dependent H4K16 Acetylation
- (2011) P. Kapoor-Vazirani et al. MOLECULAR AND CELLULAR BIOLOGY
- Interplay between HDAC3 and WDR5 Is Essential for Hypoxia-Induced Epithelial-Mesenchymal Transition
- (2011) Min-Zu Wu et al. MOLECULAR CELL
- TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
- (2011) Kristine Williams et al. NATURE
- The Polycomb complex PRC2 and its mark in life
- (2011) Raphaël Margueron et al. NATURE
- The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset
- (2011) Craig J. Ceol et al. NATURE
- A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells
- (2011) Masoud Vedadi et al. Nature Chemical Biology
- Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia
- (2011) Xiao-Jing Yan et al. NATURE GENETICS
- Genome-scale epigenetic reprogramming during epithelial-to-mesenchymal transition
- (2011) Oliver G McDonald et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion
- (2011) M Björkman et al. ONCOGENE
- Dynamic epigenetic regulation of the microRNA-200 family mediates epithelial and mesenchymal transitions in human tumorigenesis
- (2011) V Davalos et al. ONCOGENE
- The Transcription Factors Snail and Slug Activate the Transforming Growth Factor-Beta Signaling Pathway in Breast Cancer
- (2011) Archana Dhasarathy et al. PLoS One
- Structural Basis for Specific Binding of Human MPP8 Chromodomain to Histone H3 Methylated at Lysine 9
- (2011) Jing Li et al. PLoS One
- Deletion of the de novo DNA methyltransferase Dnmt3a promotes lung tumor progression
- (2011) Q. Gao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Histone H4 Lys 20 monomethylation by histone methylase SET8 mediates Wnt target gene activation
- (2011) Z. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis
- (2011) L. Shi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a
- (2011) Yanqi Chang et al. Nature Communications
- Coordinated Chromatin Control: Structural and Functional Linkage of DNA and Histone Methylation
- (2010) Xiaodong Cheng et al. BIOCHEMISTRY
- Smad Signaling Is Required to Maintain Epigenetic Silencing during Breast Cancer Progression
- (2010) P. Papageorgis et al. CANCER RESEARCH
- H3K9 Histone Methyltransferase G9a Promotes Lung Cancer Invasion and Metastasis by Silencing the Cell Adhesion Molecule Ep-CAM
- (2010) M.-W. Chen et al. CANCER RESEARCH
- Long Noncoding RNAs with Enhancer-like Function in Human Cells
- (2010) Ulf Andersson Ørom et al. CELL
- The TWIST/Mi2/NuRD protein complex and its essential role in cancer metastasis
- (2010) Junjiang Fu et al. CELL RESEARCH
- Methyl-H3K9-binding protein MPP8 mediates E-cadherin gene silencing and promotes tumour cell motility and invasion
- (2010) Kenji Kokura et al. EMBO JOURNAL
- The SNAG domain of Snail1 functions as a molecular hook for recruiting lysine-specific demethylase 1
- (2010) Yiwei Lin et al. EMBO JOURNAL
- The ZEB/miR-200 feedback loop—a motor of cellular plasticity in development and cancer?
- (2010) Simone Brabletz et al. EMBO REPORTS
- Coordinated epigenetic repression of the miR-200 family and miR-205 in invasive bladder cancer
- (2010) Erik D. Wiklund et al. INTERNATIONAL JOURNAL OF CANCER
- The Dnmt3a PWWP Domain Reads Histone 3 Lysine 36 Trimethylation and Guides DNA Methylation
- (2010) Arunkumar Dhayalan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MS-275 Sensitizes TRAIL-Resistant Breast Cancer Cells, Inhibits Angiogenesis and Metastasis, and Reverses Epithelial-Mesenchymal Transition In vivo
- (2010) R. K. Srivastava et al. MOLECULAR CANCER THERAPEUTICS
- Loss of miR-200 Inhibition of Suz12 Leads to Polycomb-Mediated Repression Required for the Formation and Maintenance of Cancer Stem Cells
- (2010) Dimitrios Iliopoulos et al. MOLECULAR CELL
- Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
- (2010) Rajnish A. Gupta et al. NATURE
- Selective inhibition of BET bromodomains
- (2010) Panagis Filippakopoulos et al. NATURE
- Bmi1 is essential in Twist1-induced epithelial–mesenchymal transition
- (2010) Muh-Hwa Yang et al. NATURE CELL BIOLOGY
- miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis
- (2010) Li Ma et al. NATURE CELL BIOLOGY
- DNMT3AMutations in Acute Myeloid Leukemia
- (2010) Timothy J. Ley et al. NEW ENGLAND JOURNAL OF MEDICINE
- Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail
- (2010) Yingying Zhang et al. NUCLEIC ACIDS RESEARCH
- ERα signaling through slug regulates E-cadherin and EMT
- (2010) Y Ye et al. ONCOGENE
- ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1
- (2010) E Sánchez-Tilló et al. ONCOGENE
- Role for DNA Methylation in the Regulation of miR-200c and miR-141 Expression in Normal and Cancer Cells
- (2010) Lukas Vrba et al. PLoS One
- Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes
- (2010) M.-C. Tsai et al. SCIENCE
- The Biology of Chromatin Remodeling Complexes
- (2009) Cedric R. Clapier et al. Annual Review of Biochemistry
- miR-200a-mediated downregulation of ZEB2 and CTNNB1 differentially inhibits nasopharyngeal carcinoma cell growth, migration and invasion
- (2009) Hongping Xia et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The multiple facets of histone H4-lysine 20 methylationThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting – Epigenetics and Chromatin Dynamics, and has undergone the Journal’s usual peer review process.
- (2009) Hongbo Yang et al. Biochemistry and Cell Biology
- E-cadherin, β-catenin, and ZEB1 in malignant progression of cancer
- (2009) Otto Schmalhofer et al. CANCER AND METASTASIS REVIEWS
- Hijacking the Chromatin Remodeling Machinery: Impact of SWI/SNF Perturbations in Cancer
- (2009) B. Weissman et al. CANCER RESEARCH
- LSD1 Is a Subunit of the NuRD Complex and Targets the Metastasis Programs in Breast Cancer
- (2009) Yan Wang et al. CELL
- MicroRNAs: Target Recognition and Regulatory Functions
- (2009) David P. Bartel CELL
- Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells
- (2009) Yohei Shimono et al. CELL
- Epithelial-Mesenchymal Transitions in Development and Disease
- (2009) Jean Paul Thiery et al. CELL
- The role of microRNAs in metastasis and epithelial-mesenchymal transition
- (2009) C. P. Bracken et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Cancer DNA Methylation: Molecular Mechanisms and Clinical Implications
- (2009) M. T. McCabe et al. CLINICAL CANCER RESEARCH
- Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX–DNMT3–DNMT3L domain
- (2009) Junji Otani et al. EMBO REPORTS
- Epigenetics and cancer treatment
- (2009) Lasse Sommer Kristensen et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- EMT: When epithelial cells decide to become mesenchymal-like cells
- (2009) Raghu Kalluri JOURNAL OF CLINICAL INVESTIGATION
- The basics of epithelial-mesenchymal transition
- (2009) Raghu Kalluri et al. JOURNAL OF CLINICAL INVESTIGATION
- Role of the polycomb protein EED in the propagation of repressive histone marks
- (2009) Raphael Margueron et al. NATURE
- Biogenesis of small RNAs in animals
- (2009) V. Narry Kim et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294
- (2009) Yanqi Chang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- A homogeneous method for investigation of methylation-dependent protein-protein interactions in epigenetics
- (2009) A. M. Quinn et al. NUCLEIC ACIDS RESEARCH
- Reexpression of epigenetically silenced AML tumor suppressor genes by SUV39H1 inhibition
- (2009) A Lakshmikuttyamma et al. ONCOGENE
- Epigenome Microarray Platform for Proteome-Wide Dissection of Chromatin-Signaling Networks
- (2009) Dennis J. Bua et al. PLoS One
- Loss of E-Cadherin Promotes Metastasis via Multiple Downstream Transcriptional Pathways
- (2008) T. T. Onder et al. CANCER RESEARCH
- A Double-Negative Feedback Loop between ZEB1-SIP1 and the microRNA-200 Family Regulates Epithelial-Mesenchymal Transition
- (2008) C. P. Bracken et al. CANCER RESEARCH
- Role of hMOF-Dependent Histone H4 Lysine 16 Acetylation in the Maintenance of TMS1/ASC Gene Activity
- (2008) P. Kapoor-Vazirani et al. CANCER RESEARCH
- Crosstalk among Histone Modifications
- (2008) Tamaki Suganuma et al. CELL
- Ajuba LIM Proteins Are Snail/Slug Corepressors Required for Neural Crest Development in Xenopus
- (2008) Ellen M. Langer et al. DEVELOPMENTAL CELL
- Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis
- (2008) Jing Yang et al. DEVELOPMENTAL CELL
- A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
- (2008) Ulrike Burk et al. EMBO REPORTS
- The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
- (2008) S.-M. Park et al. GENES & DEVELOPMENT
- The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional RepressorsZEB1andZEB2
- (2008) Manav Korpal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- 30 nm Chromatin Fibre Decompaction Requires both H4-K16 Acetylation and Linker Histone Eviction
- (2008) Philip J.J. Robinson et al. JOURNAL OF MOLECULAR BIOLOGY
- Polycomb Complex 2 Is Required for E-cadherin Repression by the Snail1 Transcription Factor
- (2008) N. Herranz et al. MOLECULAR AND CELLULAR BIOLOGY
- The LIM Protein AJUBA Recruits Protein Arginine Methyltransferase 5 To Mediate SNAIL-Dependent Transcriptional Repression
- (2008) Z. Hou et al. MOLECULAR AND CELLULAR BIOLOGY
- Direct regulation of TWIST by HIF-1α promotes metastasis
- (2008) Muh-Hwa Yang et al. NATURE CELL BIOLOGY
- The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
- (2008) Philip A. Gregory et al. NATURE CELL BIOLOGY
- The ankyrin repeats of G9a and GLP histone methyltransferases are mono- and dimethyllysine binding modules
- (2008) Robert E Collins et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes
- (2008) Silvina Epsztejn-Litman et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Repression of E-cadherin by the polycomb group protein EZH2 in cancer
- (2008) Q Cao et al. ONCOGENE
- Histone H4 lysine 20 monomethylation promotes transcriptional repression by L3MBTL1
- (2008) N Kalakonda et al. ONCOGENE
- Deacetylation of cortactin by SIRT1 promotes cell migration
- (2008) Y Zhang et al. ONCOGENE
- Genomic Loss of microRNA-101 Leads to Overexpression of Histone Methyltransferase EZH2 in Cancer
- (2008) S. Varambally et al. SCIENCE
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