SUV420H2-Mediated H4K20 Trimethylation Enforces RNA Polymerase II Promoter-Proximal Pausing by Blocking hMOF-Dependent H4K16 Acetylation

Promoter-proximal Pol II: When stalling speeds things up

(2011) Sergei Nechaev et al.   CELL CYCLE

Structural and Biochemical Studies on the Chromo-barrel Domain of Male Specific Lethal 3 (MSL3) Reveal a Binding Preference for Mono- or Dimethyllysine 20 on Histone H4

(2010) Stanley A. Moore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PR-Set7-mediated monomethylation of histone H4 lysine 20 at specific genomic regions induces transcriptional repression

(2010) Lauren M. Congdon et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Long-term Stability of Demethylation after Transient Exposure to 5-Aza-2'-Deoxycytidine Correlates with Sustained RNA Polymerase II Occupancy

(2010) J. D. Kagey et al.   MOLECULAR CANCER RESEARCH

Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET

(2010) Toshiyuki Matsui et al.   NATURE

Corecognition of DNA and a methylated histone tail by the MSL3 chromodomain

(2010) Daesung Kim et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The multiple facets of histone H4-lysine 20 methylationThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting – Epigenetics and Chromatin Dynamics, and has undergone the Journal’s usual peer review process.

(2009) Hongbo Yang et al.   Biochemistry and Cell Biology

Silencing of TMS1/ASC Promotes Resistance to Anoikis in Breast Epithelial Cells

(2009) M. J. Parsons et al.   CANCER RESEARCH

Genome-wide Mapping of HATs and HDACs Reveals Distinct Functions in Active and Inactive Genes

(2009) Zhibin Wang et al.   CELL

Histone Crosstalk between H3S10ph and H4K16ac Generates a Histone Code that Mediates Transcription Elongation

(2009) Alessio Zippo et al.   CELL

Cancer DNA Methylation: Molecular Mechanisms and Clinical Implications

(2009) M. T. McCabe et al.   CLINICAL CANCER RESEARCH

The presence of RNA polymerase II, active or stalled, predicts epigenetic fate of promoter CpG islands

(2009) H. Takeshima et al.   GENOME RESEARCH

Human Negative Elongation Factor Activates Transcription and Regulates Alternative Transcription Initiation

(2009) Jianlong Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Subunit Composition and Substrate Specificity of a MOF-containing Histone Acetyltransferase Distinct from the Male-specific Lethal (MSL) Complex

(2009) Yong Cai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Two Mammalian MOF Complexes Regulate Transcription Activation by Distinct Mechanisms

(2009) Xiangzhi Li et al.   MOLECULAR CELL

Impaired recruitment of the histone methyltransferase DOT1L contributes to the incomplete reactivation of tumor suppressor genes upon DNA demethylation

(2009) F V Jacinto et al.   ONCOGENE

Role of hMOF-Dependent Histone H4 Lysine 16 Acetylation in the Maintenance of TMS1/ASC Gene Activity

(2008) P. Kapoor-Vazirani et al.   CANCER RESEARCH

Promoter proximal pausing on genes in metazoans

(2008) David S. Gilmour   CHROMOSOMA

Loss of Histone H4K20 Trimethylation Occurs in Preneoplasia and Influences Prognosis of Non-Small Cell Lung Cancer

(2008) A. Van Den Broeck et al.   CLINICAL CANCER RESEARCH

A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse

(2008) G. Schotta et al.   GENES & DEVELOPMENT

NELF-mediated stalling of Pol II can enhance gene expression by blocking promoter-proximal nucleosome assembly

(2008) D. A. Gilchrist et al.   GENES & DEVELOPMENT

Preferential Dimethylation of Histone H4 Lysine 20 by Suv4-20

(2008) Hongbo Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bromodomain 4 activation predicts breast cancer survival

(2008) N. P. S. Crawford et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nascent RNA Sequencing Reveals Widespread Pausing and Divergent Initiation at Human Promoters

(2008) Leighton J. Core et al.   SCIENCE