标题
Biomolecular condensates in neurodegeneration and cancer
作者
关键词
-
出版物
TRAFFIC
Volume 20, Issue 12, Pages 890-911
出版商
Wiley
发表日期
2019-10-13
DOI
10.1111/tra.12704
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Aberrant Phase Transitions: Side Effects and Novel Therapeutic Strategies in Human Disease
- (2019) Veronica Verdile et al. Frontiers in Genetics
- Cycles of protein condensation and discharge in nuclear organelles studied by fluorescence lifetime imaging
- (2019) Artem Pliss et al. Nature Communications
- Membraneless organelles: P granules in C. elegans
- (2019) Elisabeth A. Marnik et al. TRAFFIC
- A molecular assembly phase transition and kinetic proofreading modulate Ras activation by SOS
- (2019) William Y. C. Huang et al. SCIENCE
- Stoichiometry controls activity of phase-separated clusters of actin signaling proteins
- (2019) Lindsay B. Case et al. SCIENCE
- Phosphoregulated FMRP phase separation models activity-dependent translation through bidirectional control of mRNA granule formation
- (2019) Brian Tsang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Super-enhancers in cancer
- (2019) Palaniraja Thandapani PHARMACOLOGY & THERAPEUTICS
- Phase separation of ligand-activated enhancers licenses cooperative chromosomal enhancer assembly
- (2019) Sreejith J. Nair et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Bridging biophysics and neurology: aberrant phase transitions in neurodegenerative disease
- (2019) Natalia B. Nedelsky et al. Nature Reviews Neurology
- Matter over mind: Liquid phase separation and neurodegeneration
- (2019) Shana Elbaum-Garfinkle JOURNAL OF BIOLOGICAL CHEMISTRY
- Wnt/Beta-Catenin Signaling Regulation and a Role for Biomolecular Condensates
- (2019) Kristina N. Schaefer et al. DEVELOPMENTAL CELL
- PARylation regulates stress granule dynamics, phase separation, and neurotoxicity of disease-related RNA-binding proteins
- (2019) Yongjia Duan et al. CELL RESEARCH
- Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates
- (2019) Simon Alberti et al. CELL
- Regulation of Transmembrane Signaling by Phase Separation
- (2019) Lindsay B. Case et al. Annual Review of Biophysics
- Quantitative bioimage analytics enables measurement of targeted cellular stress response induced by celastrol-loaded nanoparticles
- (2019) Erik Niemelä et al. CELL STRESS & CHAPERONES
- Phase separation of RNA-binding proteins in physiology and disease: An introduction to the JBC Reviews thematic series
- (2019) James Shorter JOURNAL OF BIOLOGICAL CHEMISTRY
- Liquid-liquid phase separation of tau protein: The crucial role of electrostatic interactions
- (2019) Solomiia Boyko et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- N-terminal sequences in matrin 3 mediate phase separation into droplet-like structures that recruit TDP43 variants lacking RNA binding elements
- (2019) M. Carolina Gallego-Iradi et al. LABORATORY INVESTIGATION
- PARP-1 Activation Directs FUS to DNA Damage Sites to Form PARG-Reversible Compartments Enriched in Damaged DNA
- (2019) Anastasia S. Singatulina et al. Cell Reports
- Chronic optogenetic induction of stress granules is cytotoxic and reveals the evolution of ALS-FTD pathology
- (2019) Peipei Zhang et al. eLife
- Phase separation of 53 BP 1 determines liquid‐like behavior of DNA repair compartments
- (2019) Sinan Kilic et al. EMBO JOURNAL
- Clustered telomeres in phase-separated nuclear condensates engage mitotic DNA synthesis through BLM and RAD52
- (2019) Jaewon Min et al. GENES & DEVELOPMENT
- Engineered protein disaggregases mitigate toxicity of aberrant prion-like fusion proteins underlying sarcoma
- (2019) Jeremy J. Ryan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- m6A enhances the phase separation potential of mRNA
- (2019) Ryan J. Ries et al. NATURE
- Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD
- (2019) Mark Y. Fang et al. NEURON
- DAXX in cancer: phenomena, processes, mechanisms and regulation
- (2019) Iqbal Mahmud et al. NUCLEIC ACIDS RESEARCH
- Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites
- (2019) Marta Alenquer et al. Nature Communications
- A composition-dependent molecular clutch between T cell signaling condensates and actin
- (2019) Jonathon A Ditlev et al. eLife
- Proximity RNA Labeling by APEX-Seq Reveals the Organization of Translation Initiation Complexes and Repressive RNA Granules
- (2019) Alejandro Padrón et al. MOLECULAR CELL
- CPEB3 inhibits translation of mRNA targets by localizing them to P bodies
- (2019) Lenzie Ford et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phospho-dependent phase separation of FMRP and CAPRIN1 recapitulates regulation of translation and deadenylation
- (2019) Tae Hun Kim et al. SCIENCE
- Theories for Sequence-Dependent Phase Behaviors of Biomolecular Condensates
- (2018) Yi-Hsuan Lin et al. BIOCHEMISTRY
- P-Bodies: Composition, Properties, and Functions
- (2018) Yang Luo et al. BIOCHEMISTRY
- The physical forces mediating self-association and phase-separation in the C-terminal domain of TDP-43
- (2018) Hao-Ru Li et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- The physiological and pathological biophysics of phase separation and gelation of RNA binding proteins in amyotrophic lateral sclerosis and fronto-temporal lobar degeneration
- (2018) Peter St George-Hyslop et al. BRAIN RESEARCH
- Surface Properties Determining Passage Rates of Proteins through Nuclear Pores
- (2018) Steffen Frey et al. CELL
- Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites
- (2018) Takuya Yoshizawa et al. CELL
- Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation
- (2018) Mario Hofweber et al. CELL
- Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules
- (2018) Sebastian Markmiller et al. CELL
- A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins
- (2018) Jie Wang et al. CELL
- Stress Granule Assembly Disrupts Nucleocytoplasmic Transport
- (2018) Ke Zhang et al. CELL
- Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains
- (2018) Lin Guo et al. CELL
- FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions
- (2018) Seema Qamar et al. CELL
- Polyubiquitin chain-induced p62 phase separation drives autophagic cargo segregation
- (2018) Daxiao Sun et al. CELL RESEARCH
- Tau protein liquid–liquid phase separation can initiate tau aggregation
- (2018) Susanne Wegmann et al. EMBO JOURNAL
- Acetylation Disfavors Tau Phase Separation
- (2018) Josephine Ferreon et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- TAR DNA-binding protein 43 (TDP-43) liquid–liquid phase separation is mediated by just a few aromatic residues
- (2018) Hao-Ru Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Prion-like low-complexity sequences: Key regulators of protein solubility and phase behavior
- (2018) Titus Franzmann et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Aggregation, Phase Separation and Spatial Morphologies of the Assemblies of FG Nucleoporins
- (2018) Anton Zilman JOURNAL OF MOLECULAR BIOLOGY
- Is DNA damage indispensable for stress-induced senescence?
- (2018) Anna Bielak-Zmijewska et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Ubiquitin Modulates Liquid-Liquid Phase Separation of UBQLN2 via Disruption of Multivalent Interactions
- (2018) Thuy P. Dao et al. MOLECULAR CELL
- Protein Dynamics in Complex DNA Lesions
- (2018) Radoslav Aleksandrov et al. MOLECULAR CELL
- Mechanistic View of hnRNPA2 Low-Complexity Domain Structure, Interactions, and Phase Separation Altered by Mutation and Arginine Methylation
- (2018) Veronica H. Ryan et al. MOLECULAR CELL
- High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies
- (2018) Ji-Young Youn et al. MOLECULAR CELL
- Functional Domains of NEAT1 Architectural lncRNA Induce Paraspeckle Assembly through Phase Separation
- (2018) Tomohiro Yamazaki et al. MOLECULAR CELL
- The functional roles of PML nuclear bodies in genome maintenance
- (2018) Hae Ryung Chang et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD
- (2018) Ching-Chieh Chou et al. NATURE NEUROSCIENCE
- Controlling compartmentalization by non-membrane-bound organelles
- (2018) Richard J. Wheeler et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- RNA self-assembly contributes to stress granule formation and defining the stress granule transcriptome
- (2018) Briana Van Treeck et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RNA buffers the phase separation behavior of prion-like RNA binding proteins
- (2018) Shovamayee Maharana et al. SCIENCE
- mRNA structure determines specificity of a polyQ-driven phase separation
- (2018) Erin M. Langdon et al. SCIENCE
- Imaging dynamic and selective low-complexity domain interactions that control gene transcription
- (2018) Shasha Chong et al. SCIENCE
- A liquid phase of synapsin and lipid vesicles
- (2018) Dragomir Milovanovic et al. SCIENCE
- Coactivator condensation at super-enhancers links phase separation and gene control
- (2018) Benjamin R. Sabari et al. SCIENCE
- Mediator and RNA polymerase II clusters associate in transcription-dependent condensates
- (2018) Won-Ki Cho et al. SCIENCE
- Phase separation of a yeast prion protein promotes cellular fitness
- (2018) Titus M. Franzmann et al. SCIENCE
- Organization and Function of Non-dynamic Biomolecular Condensates
- (2018) Jeffrey B. Woodruff et al. TRENDS IN BIOCHEMICAL SCIENCES
- Paraspeckles: Where Long Noncoding RNA Meets Phase Separation
- (2018) Archa H. Fox et al. TRENDS IN BIOCHEMICAL SCIENCES
- Nuclear microtubule filaments mediate non-linear directional motion of chromatin and promote DNA repair
- (2018) Roxanne Oshidari et al. Nature Communications
- Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation
- (2018) Marcel Naumann et al. Nature Communications
- PML: Regulation and multifaceted function beyond tumor suppression
- (2018) Kuo-Sheng Hsu et al. Cell and Bioscience
- Pi-Pi contacts are an overlooked protein feature relevant to phase separation
- (2018) Robert McCoy Vernon et al. eLife
- Proteasome storage granules protect proteasomes from autophagic degradation upon carbon starvation
- (2018) Richard S Marshall et al. eLife
- A multicentre observational study on management of general anaesthesia in elderly patients at high-risk of postoperative adverse outcomes
- (2018) Serge Molliex et al. Anaesthesia Critical Care & Pain Medicine
- Protein Phase Separation Provides Long-Term Memory of Transient Spatial Stimuli
- (2018) Elliot Dine et al. Cell Systems
- Tdrd6a Regulates the Aggregation of Buc into Functional Subcellular Compartments that Drive Germ Cell Specification
- (2018) Elke F. Roovers et al. DEVELOPMENTAL CELL
- Who's In and Who's Out—Compositional Control of Biomolecular Condensates
- (2018) Jonathon A. Ditlev et al. JOURNAL OF MOLECULAR BIOLOGY
- The P Granules of C. elegans: A Genetic Model for the Study of RNA–Protein Condensates
- (2018) Geraldine Seydoux JOURNAL OF MOLECULAR BIOLOGY
- Cancer Mutations of the Tumor Suppressor SPOP Disrupt the Formation of Active, Phase-Separated Compartments
- (2018) Jill J. Bouchard et al. MOLECULAR CELL
- Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization
- (2018) Leeanne McGurk et al. MOLECULAR CELL
- α-Proteobacterial RNA Degradosomes Assemble Liquid-Liquid Phase-Separated RNP Bodies
- (2018) Nadra Al-Husini et al. MOLECULAR CELL
- C9orf72-mediated ALS and FTD: multiple pathways to disease
- (2018) Rubika Balendra et al. Nature Reviews Neurology
- RNA polymerase II clustering through carboxy-terminal domain phase separation
- (2018) Marc Boehning et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Phase separated microenvironments inside the cell nucleus are linked to disease and regulate epigenetic state, transcription and RNA processing
- (2018) Iain A. Sawyer et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Phase Transitions Drive the Formation of Vesicular Stomatitis Virus Replication Compartments
- (2018) Bianca S. Heinrich et al. mBio
- Mutant FUS causes DNA ligation defects to inhibit oxidative damage repair in Amyotrophic Lateral Sclerosis
- (2018) Haibo Wang et al. Nature Communications
- Stress-Induced Low Complexity RNA Activates Physiological Amyloidogenesis
- (2018) Miling Wang et al. Cell Reports
- Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains
- (2018) Ann Boija et al. CELL
- A Membraneless Organelle Associated with the Endoplasmic Reticulum Enables 3′UTR-Mediated Protein-Protein Interactions
- (2018) Weirui Ma et al. CELL
- Mapping Local and Global Liquid Phase Behavior in Living Cells Using Photo-Oligomerizable Seeds
- (2018) Dan Bracha et al. CELL
- Relation Between Stress Granules and Cytoplasmic Protein Aggregates Linked to Neurodegenerative Diseases
- (2018) Ioana Dobra et al. Current Neurology and Neuroscience Reports
- 53BP1: A key player of DNA damage response with critical functions in cancer
- (2018) Mohammad Mirza-Aghazadeh-Attari et al. DNA REPAIR
- Bacterial FtsZ protein forms phase‐separated condensates with its nucleoid‐associated inhibitor SlmA
- (2018) Begoña Monterroso et al. EMBO REPORTS
- Friend or foe — post-translational modifications as regulators of phase separation and RNP granule dynamics
- (2018) Mario Hofweber et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity
- (2018) Fionna E. Loughlin et al. MOLECULAR CELL
- Acetylation of intrinsically disordered regions regulates phase separation
- (2018) Makoto Saito et al. Nature Chemical Biology
- Membraneless nuclear organelles and the search for phases within phases
- (2018) Iain A. Sawyer et al. Wiley Interdisciplinary Reviews-RNA
- Protein gradients on the nucleoid position the carbon-fixing organelles of cyanobacteria
- (2018) Joshua S MacCready et al. eLife
- Phase separation as a mechanism for assembling dynamic postsynaptic density signalling complexes
- (2018) Zhe Feng et al. CURRENT OPINION IN NEUROBIOLOGY
- The glycolytic enzyme phosphofructokinase-1 assembles into filaments
- (2017) Bradley A. Webb et al. JOURNAL OF CELL BIOLOGY
- P-Body Purification Reveals the Condensation of Repressed mRNA Regulons
- (2017) Arnaud Hubstenberger et al. MOLECULAR CELL
- Phase separation drives heterochromatin domain formation
- (2017) Amy R. Strom et al. NATURE
- RNA phase transitions in repeat expansion disorders
- (2017) Ankur Jain et al. NATURE
- Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin
- (2017) Adam G. Larson et al. NATURE
- Biomolecular condensates: organizers of cellular biochemistry
- (2017) Salman F. Banani et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Polyglutamine-Expanded Huntingtin Exacerbates Age-Related Disruption of Nuclear Integrity and Nucleocytoplasmic Transport
- (2017) Fatima Gasset-Rosa et al. NEURON
- TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics
- (2017) Ian R. Mackenzie et al. NEURON
- Mutant Huntingtin Disrupts the Nuclear Pore Complex
- (2017) Jonathan C. Grima et al. NEURON
- Aberrant distributions of nuclear pore complex proteins in ALS mice and ALS patients
- (2017) Jingwei Shang et al. NEUROSCIENCE
- Nuclear speckles: molecular organization, biological function and role in disease
- (2017) Lukasz Galganski et al. NUCLEIC ACIDS RESEARCH
- Relationships between Stress Granules, Oxidative Stress, and Neurodegenerative Diseases
- (2017) Lihua Chen et al. Oxidative Medicine and Cellular Longevity
- Amyotrophic lateral sclerosis-linked mutations increase the viscosity of liquid-like TDP-43 RNP granules in neurons
- (2017) Pallavi P. Gopal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Toxic PRnpoly-dipeptides encoded by theC9orf72repeat expansion block nuclear import and export
- (2017) Kevin Y. Shi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Coordinating cell cycle-regulated histone gene expression through assembly and function of the Histone Locus Body
- (2017) Robert J. Duronio et al. RNA Biology
- ATP as a biological hydrotrope
- (2017) Avinash Patel et al. SCIENCE
- A New View into the Regulation of Purine Metabolism: The Purinosome
- (2017) Anthony M. Pedley et al. TRENDS IN BIOCHEMICAL SCIENCES
- Liquid–liquid phase separation of the microtubule-binding repeats of the Alzheimer-related protein Tau
- (2017) Susmitha Ambadipudi et al. Nature Communications
- Glycolytic Enzymes Coalesce in G Bodies under Hypoxic Stress
- (2017) Meiyan Jin et al. Cell Reports
- ALS/FTD-Associated C9ORF72 Repeat RNA Promotes Phase Transitions In Vitro and in Cells
- (2017) Marta M. Fay et al. Cell Reports
- Local Nucleation of Microtubule Bundles through Tubulin Concentration into a Condensed Tau Phase
- (2017) Amayra Hernández-Vega et al. Cell Reports
- Localizing order to boost signaling
- (2017) Štefan Bálint et al. eLife
- The synaptonemal complex has liquid crystalline properties and spatially regulates meiotic recombination factors
- (2017) Ofer Rog et al. eLife
- Role of Y Box Protein-1 in cancer: As potential biomarker and novel therapeutic target
- (2017) Pramod Kumar Maurya et al. Journal of Cancer
- Potential Role of Phase Separation of Repetitive DNA in Chromosomal Organization
- (2017) Shao-Jun Tang Genes
- Cajal body function in genome organization and transcriptome diversity
- (2016) Iain A. Sawyer et al. BIOESSAYS
- Amyloid-like Self-Assembly of a Cellular Compartment
- (2016) Elvan Boke et al. CELL
- Mechanisms and Consequences of Macromolecular Phase Separation
- (2016) Louis-Philippe Bergeron-Sandoval et al. CELL
- The Nuclear Pore Complex as a Flexible and Dynamic Gate
- (2016) Kevin E. Knockenhauer et al. CELL
- Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic Plasticity
- (2016) Menglong Zeng et al. CELL
- Mutant KRAS Enhances Tumor Cell Fitness by Upregulating Stress Granules
- (2016) Elda Grabocka et al. CELL
- Polar Positioning of Phase-Separated Liquid Compartments in Cells Regulated by an mRNA Competition Mechanism
- (2016) Shambaditya Saha et al. CELL
- ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure
- (2016) Saumya Jain et al. CELL
- Compositional Control of Phase-Separated Cellular Bodies
- (2016) Salman F. Banani et al. CELL
- Coexisting Liquid Phases Underlie Nucleolar Subcompartments
- (2016) Marina Feric et al. CELL
- Phase separation in biology; functional organization of a higher order
- (2016) Diana M. Mitrea et al. Cell Communication and Signaling
- Nucleation by rRNA Dictates the Precision of Nucleolus Assembly
- (2016) Hanieh Falahati et al. CURRENT BIOLOGY
- Liquid–liquid phase separation in cellular signaling systems
- (2016) P Andrew Chong et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Adaptation to Stressors by Systemic Protein Amyloidogenesis
- (2016) Timothy E. Audas et al. DEVELOPMENTAL CELL
- Higher‐order oligomerization promotes localization of SPOP to liquid nuclear speckles
- (2016) Melissa R Marzahn et al. EMBO JOURNAL
- Arginine Demethylation of G3BP1 Promotes Stress Granule Assembly
- (2016) Wei-Chih Tsai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mechanistic insights into mammalian stress granule dynamics
- (2016) Marc D. Panas et al. JOURNAL OF CELL BIOLOGY
- G3BP–Caprin1–USP10 complexes mediate stress granule condensation and associate with 40S subunits
- (2016) Nancy Kedersha et al. JOURNAL OF CELL BIOLOGY
- The C-Terminal RGG Domain of Human Lsm4 Promotes Processing Body Formation Stimulated by Arginine Dimethylation
- (2016) Marcos Arribas-Layton et al. MOLECULAR AND CELLULAR BIOLOGY
- A Surveillance Function of the HSPB8-BAG3-HSP70 Chaperone Complex Ensures Stress Granule Integrity and Dynamism
- (2016) Massimo Ganassi et al. MOLECULAR CELL
- Ki-67 acts as a biological surfactant to disperse mitotic chromosomes
- (2016) Sara Cuylen et al. NATURE
- Membraneless organelles can melt nucleic acid duplexes and act as biomolecular filters
- (2016) Timothy J. Nott et al. Nature Chemistry
- Glycolytic Enzymes Localize to Synapses under Energy Stress to Support Synaptic Function
- (2016) SoRi Jang et al. NEURON
- Mouse oocytes differentiate through organelle enrichment from sister cyst germ cells
- (2016) L. Lei et al. SCIENCE
- Phase separation of signaling molecules promotes T cell receptor signal transduction
- (2016) Xiaolei Su et al. SCIENCE
- ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain
- (2016) Alexander E. Conicella et al. STRUCTURE
- Transport Selectivity of Nuclear Pores, Phase Separation, and Membraneless Organelles
- (2016) H. Broder Schmidt et al. TRENDS IN BIOCHEMICAL SCIENCES
- Principles and Properties of Stress Granules
- (2016) David S.W. Protter et al. TRENDS IN CELL BIOLOGY
- Cross-β Polymerization of Low Complexity Sequence Domains
- (2016) Masato Kato et al. Cold Spring Harbor Perspectives in Biology
- PML nuclear body disruption impairs DNA double-strand break sensing and repair in APL
- (2016) A di Masi et al. Cell Death & Disease
- Cancer-associated DDX3X mutations drive stress granule assembly and impair global translation
- (2016) Yasmine A. Valentin-Vega et al. Scientific Reports
- In vivo vizualisation of mono-ADP-ribosylation by dPARP16 upon amino-acid starvation
- (2016) Angelica Aguilera-Gomez et al. eLife
- A pH-driven transition of the cytoplasm from a fluid- to a solid-like state promotes entry into dormancy
- (2016) Matthias Christoph Munder et al. eLife
- RNA Polymerase II cluster dynamics predict mRNA output in living cells
- (2016) Won-Ki Cho et al. eLife
- Nucleophosmin integrates within the nucleolus via multi-modal interactions with proteins displaying R-rich linear motifs and rRNA
- (2016) Diana M Mitrea et al. eLife
- Distinct stages in stress granule assembly and disassembly
- (2016) Joshua R Wheeler et al. eLife
- Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD
- (2016) Steven Boeynaems et al. Scientific Reports
- Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization
- (2015) Amandine Molliex et al. CELL
- A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
- (2015) Avinash Patel et al. CELL
- Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects
- (2015) Jerome Mertens et al. Cell Stem Cell
- Inverse Size Scaling of the Nucleolus by a Concentration-Dependent Phase Transition
- (2015) Stephanie C. Weber et al. CURRENT BIOLOGY
- Actin and Endocytosis in Budding Yeast
- (2015) Bruce L. Goode et al. GENETICS
- Intracellular Bacterial Pathogens Trigger the Formation of U Small Nuclear RNA Bodies (U Bodies) through Metabolic Stress Induction
- (2015) Jessica Tsalikis et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- YB-1 regulates stress granule formation and tumor progression by translationally activating G3BP1
- (2015) Syam Prakash Somasekharan et al. JOURNAL OF CELL BIOLOGY
- Prion-like domains in RNA binding proteins are essential for building subnuclear paraspeckles
- (2015) Sven Hennig et al. JOURNAL OF CELL BIOLOGY
- SPOP Promotes Ubiquitination and Degradation of the ERG Oncoprotein to Suppress Prostate Cancer Progression
- (2015) Wenjian Gan et al. MOLECULAR CELL
- RNA Controls PolyQ Protein Phase Transitions
- (2015) Huaiying Zhang et al. MOLECULAR CELL
- Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins
- (2015) Yuan Lin et al. MOLECULAR CELL
- Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II
- (2015) Kathleen A. Burke et al. MOLECULAR CELL
- Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles
- (2015) Timothy J. Nott et al. MOLECULAR CELL
- DNA damage in neurodegenerative diseases
- (2015) Fabio Coppedè et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- The C9orf72 repeat expansion disrupts nucleocytoplasmic transport
- (2015) Ke Zhang et al. NATURE
- Integration of actin dynamics and cell adhesion by a three-dimensional, mechanosensitive molecular clutch
- (2015) Lindsay B. Case et al. NATURE CELL BIOLOGY
- ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function
- (2015) Tetsuro Murakami et al. NEURON
- Conserved interdomain linker promotes phase separation of the multivalent adaptor protein Nck
- (2015) Sudeep Banjade et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RNA transcription modulates phase transition-driven nuclear body assembly
- (2015) Joel Berry et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing
- (2015) Saravana P. Selvanathan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics
- (2015) Shana Elbaum-Garfinkle et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulated assembly of a supramolecular centrosome scaffold in vitro
- (2015) J. B. Woodruff et al. SCIENCE
- Alterations in stress granule dynamics driven by TDP-43 and FUS: a link to pathological inclusions in ALS?
- (2015) Anaïs Aulas et al. Frontiers in Cellular Neuroscience
- Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)
- (2015) Matthias Altmeyer et al. Nature Communications
- Nup98 FG domains from diverse species spontaneously phase-separate into particles with nuclear pore-like permselectivity
- (2015) Hermann Broder Schmidt et al. eLife
- SPOP mutation leads to genomic instability in prostate cancer
- (2015) Gunther Boysen et al. eLife
- Actin and Endocytosis in Budding Yeast
- (2015) Bruce L. Goode et al. GENETICS
- The Role of Oxidative Stress in Neurodegenerative Diseases
- (2015) Geon Ha Kim et al. Experimental Neurobiology
- Liquid-Liquid Phase Separation in Biology
- (2014) Anthony A. Hyman et al. Annual Review of Cell and Developmental Biology
- SPOP Promotes Tumorigenesis by Acting as a Key Regulatory Hub in Kidney Cancer
- (2014) Guoqiang Li et al. CANCER CELL
- Speckle-type POZ protein, SPOP, is involved in the DNA damage response
- (2014) D. Zhang et al. CARCINOGENESIS
- Assemblages: Functional units formed by cellular phase separation
- (2014) Jeffrey A. Toretsky et al. JOURNAL OF CELL BIOLOGY
- ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects
- (2014) Haiyan Qiu et al. JOURNAL OF CLINICAL INVESTIGATION
- FUS is Phosphorylated by DNA-PK and Accumulates in the Cytoplasm after DNA Damage
- (2014) Q. Deng et al. JOURNAL OF NEUROSCIENCE
- Long Noncoding RNA NEAT1-Dependent SFPQ Relocation from Promoter Region to Paraspeckle Mediates IL8 Expression upon Immune Stimuli
- (2014) Katsutoshi Imamura et al. MOLECULAR CELL
- Axonal Transport of TDP-43 mRNA Granules Is Impaired by ALS-Causing Mutations
- (2014) Nael H. Alami et al. NEURON
- Pericentriolar material structure and dynamics
- (2014) J. B. Woodruff et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- mRNP granules
- (2014) J Ross Buchan RNA Biology
- RanBP2/Nup358 Potentiates the Translation of a Subset of mRNAs Encoding Secretory Proteins
- (2014) Kohila Mahadevan et al. PLOS BIOLOGY
- A stress assembly that confers cell viability by preserving ERES components during amino-acid starvation
- (2014) Margarita Zacharogianni et al. eLife
- Phase transitions of multivalent proteins can promote clustering of membrane receptors
- (2014) Sudeep Banjade et al. eLife
- Filament formation by metabolic enzymes is a specific adaptation to an advanced state of cellular starvation
- (2014) Ivana Petrovska et al. eLife
- PML nuclear bodies: Assembly and oxidative stress-sensitive sumoylation
- (2014) Umut Sahin et al. Nucleus
- Cytoplasmic RNA Granules and Viral Infection
- (2014) Wei-Chih Tsai et al. Annual Review of Virology
- Uncovering Nuclear Pore Complexity with Innovation
- (2013) Rebecca L. Adams et al. CELL
- Eukaryotic Stress Granules Are Cleared by Autophagy and Cdc48/VCP Function
- (2013) J. Ross Buchan et al. CELL
- Phosphorylation-Regulated Binding of RNA Polymerase II to Fibrous Polymers of Low-Complexity Domains
- (2013) Ilmin Kwon et al. CELL
- Altered Ribostasis: RNA-Protein Granules in Degenerative Disorders
- (2013) Mani Ramaswami et al. CELL
- Stress granules in neurodegeneration - lessons learnt from TAR DNA binding protein of 43 kDa and fused in sarcoma
- (2013) Eva Bentmann et al. FEBS Journal
- Compromised paraspeckle formation as a pathogenic factor in FUSopathies
- (2013) Tatyana A. Shelkovnikova et al. HUMAN MOLECULAR GENETICS
- The RNA-binding Protein Fused in Sarcoma (FUS) Functions Downstream of Poly(ADP-ribose) Polymerase (PARP) in Response to DNA Damage
- (2013) Adam S. Mastrocola et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies
- (2013) Tetsuro Hirose et al. MOLECULAR BIOLOGY OF THE CELL
- A nuclear F-actin scaffold stabilizes ribonucleoprotein droplets against gravity in large cells
- (2013) Marina Feric et al. NATURE CELL BIOLOGY
- Interaction of FUS and HDAC1 regulates DNA damage response and repair in neurons
- (2013) Wen-Yuan Wang et al. NATURE NEUROSCIENCE
- PARP-1 dependent recruitment of the amyotrophic lateral sclerosis-associated protein FUS/TLS to sites of oxidative DNA damage
- (2013) Stuart L. Rulten et al. NUCLEIC ACIDS RESEARCH
- Identification of Novel Stress Granule Components That Are Involved in Nuclear Transport
- (2013) Hicham Mahboubi et al. PLoS One
- Real-Time Dynamics of RNA Polymerase II Clustering in Live Human Cells
- (2013) I. I. Cisse et al. SCIENCE
- Differential Roles of PML Isoforms
- (2013) Sébastien Nisole et al. Frontiers in Oncology
- Receptor Signaling Clusters in the Immune Synapse
- (2012) Michael L. Dustin et al. Annual Review of Biophysics
- The Permeability of Reconstituted Nuclear Pores Provides Direct Evidence for the Selective Phase Model
- (2012) Bastian B. Hülsmann et al. CELL
- Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels
- (2012) Masato Kato et al. CELL
- Arginine methylation next to the PY-NLS modulates Transportin binding and nuclear import of FUS
- (2012) Dorothee Dormann et al. EMBO JOURNAL
- SRSF1 regulates the assembly of pre-mRNA processing factors in nuclear speckles
- (2012) Vidisha Tripathi et al. MOLECULAR BIOLOGY OF THE CELL
- Phase transitions in the assembly of multivalent signalling proteins
- (2012) Pilong Li et al. NATURE
- Mechanism of Oxidative Stress in Neurodegeneration
- (2012) Sonia Gandhi et al. Oxidative Medicine and Cellular Longevity
- Structural and energetic basis of ALS-causing mutations in the atypical proline–tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS)
- (2012) Zi Chao Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- P-Bodies and Stress Granules: Possible Roles in the Control of Translation and mRNA Degradation
- (2012) C. J. Decker et al. Cold Spring Harbor Perspectives in Biology
- Single Molecule Study of the Intrinsically Disordered FG-Repeat Nucleoporin 153
- (2011) Sigrid Milles et al. BIOPHYSICAL JOURNAL
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Gem formation upon constitutive Gemin3 overexpression inDrosophila
- (2011) Ruben J. Cauchi CELL BIOLOGY INTERNATIONAL
- A view of nuclear Polycomb bodies
- (2011) Vincenzo Pirrotta et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Beyond Stereospecificity: Liquids and Mesoscale Organization of Cytoplasm
- (2011) Anthony A. Hyman et al. DEVELOPMENTAL CELL
- Replication stress induces 53BP1-containing OPT domains in G1 cells
- (2011) Jeanine A. Harrigan et al. JOURNAL OF CELL BIOLOGY
- Poly(ADP-Ribose) Regulates Stress Responses and MicroRNA Activity in the Cytoplasm
- (2011) Anthony K.L. Leung et al. MOLECULAR CELL
- Nucleation of nuclear bodies by RNA
- (2011) Sergey P. Shevtsov et al. NATURE CELL BIOLOGY
- Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes
- (2011) C. P. Brangwynne et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- DNA repair deficiency in neurodegeneration
- (2011) Dennis Kjølhede Jeppesen et al. PROGRESS IN NEUROBIOLOGY
- The Postsynaptic Organization of Synapses
- (2011) M. Sheng et al. Cold Spring Harbor Perspectives in Biology
- RNA Granules in Germ Cells
- (2011) E. Voronina et al. Cold Spring Harbor Perspectives in Biology
- Identification of importin α1 as a novel constituent of RNA stress granules
- (2010) Ken Fujimura et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Two-step colocalization of MORC3 with PML nuclear bodies
- (2010) Y. Mimura et al. JOURNAL OF CELL SCIENCE
- The Perinucleolar Compartment
- (2010) C. Pollock et al. Cold Spring Harbor Perspectives in Biology
- Nuclear Stress Bodies
- (2010) G. Biamonti et al. Cold Spring Harbor Perspectives in Biology
- The Cajal Body and Histone Locus Body
- (2010) Z. Nizami et al. Cold Spring Harbor Perspectives in Biology
- Cell Biology of Prokaryotic Organelles
- (2010) D. Murat et al. Cold Spring Harbor Perspectives in Biology
- Nuclear Speckles
- (2010) D. L. Spector et al. Cold Spring Harbor Perspectives in Biology
- The Nucleolus
- (2010) T. Pederson Cold Spring Harbor Perspectives in Biology
- PML Nuclear Bodies
- (2010) V. Lallemand-Breitenbach et al. Cold Spring Harbor Perspectives in Biology
- Microtubules govern stress granule mobility and dynamics
- (2009) Elena S. Nadezhdina et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Role of Microtubules in Stress Granule Assembly
- (2009) Konstantin G. Chernov et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dynein and kinesin regulate stress-granule and P-body dynamics
- (2009) M. Loschi et al. JOURNAL OF CELL SCIENCE
- Nuclear Contour Irregularity and Abnormal Transporter Protein Distribution in Anterior Horn Cells in Amyotrophic Lateral Sclerosis
- (2009) Yoshimi Kinoshita et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- An Architectural Role for a Nuclear Noncoding RNA: NEAT1 RNA Is Essential for the Structure of Paraspeckles
- (2009) Christine M. Clemson et al. MOLECULAR CELL
- A role for transportin in deposition of TTP to cytoplasmic RNA granules and mRNA decay
- (2009) Wei-Lun Chang et al. NUCLEIC ACIDS RESEARCH
- Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation
- (2009) C. P. Brangwynne et al. SCIENCE
- PML Activates Transcription by Protecting HIPK2 and p300 from SCFFbx3-Mediated Degradation
- (2008) Y. Shima et al. MOLECULAR AND CELLULAR BIOLOGY
- 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility
- (2008) Nadya Dimitrova et al. NATURE
- Assessment of protein dynamics and DNA repair following generation of DNA double-strand breaks at defined genomic sites
- (2008) Elijahu Berkovich et al. Nature Protocols
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now