Stoichiometry controls activity of phase-separated clusters of actin signaling proteins

A molecular assembly phase transition and kinetic proofreading modulate Ras activation by SOS

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Switch-like Arp2/3 activation upon WASP and WIP recruitment to an apparent threshold level by multivalent linker proteins in vivo

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Phosphotyrosine-mediated LAT assembly on membranes drives kinetic bifurcation in recruitment dynamics of the Ras activator SOS

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Phase separation of signaling molecules promotes T cell receptor signal transduction

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Identification of an ATP-controlled allosteric switch that controls actin filament nucleation by Arp2/3 complex

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Conserved interdomain linker promotes phase separation of the multivalent adaptor protein Nck

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Visualizing the functional architecture of the endocytic machinery

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Phase transitions of multivalent proteins can promote clustering of membrane receptors

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Nck-mediated recruitment of BCAP to the BCR regulates the PI(3)K-Akt pathway in B cells

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Pathway of actin filament branch formation by Arp2/3 complex revealed by single-molecule imaging

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Three-color single molecule imaging shows WASP detachment from Arp2/3 complex triggers actin filament branch formation

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Stoichiometry of Nck-dependent actin polymerization in living cells

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Phase transitions in the assembly of multivalent signalling proteins

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Fast rebinding increases dwell time of Src homology 2 (SH2)-containing proteins near the plasma membrane

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Arp2/3 complex is bound and activated by two WASP proteins

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Hierarchical Regulation of WASP/WAVE Proteins

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