Arginine Demethylation of G3BP1 Promotes Stress Granule Assembly

Biochemistry and regulation of the protein arginine methyltransferases (PRMTs)

(2016) Yalemi Morales et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure

(2016) Saumya Jain et al.   CELL

G3BP–Caprin1–USP10 complexes mediate stress granule condensation and associate with 40S subunits

(2016) Nancy Kedersha et al.   JOURNAL OF CELL BIOLOGY

Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5

(2016) Konstantinos J. Mavrakis et al.   SCIENCE

MTAPdeletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells

(2016) Gregory V. Kryukov et al.   SCIENCE

TIA1 oxidation inhibits stress granule assembly and sensitizes cells to stress-induced apoptosis

(2016) Kyoko Arimoto-Matsuzaki et al.   Nature Communications

A Potent, Selective, and Cell-Active Inhibitor of Human Type I Protein Arginine Methyltransferases

(2015) Mohammad S. Eram et al.   ACS Chemical Biology

The oxygenase Jmjd6–a case study in conflicting assignments

(2015) Angelika Böttger et al.   BIOCHEMICAL JOURNAL

Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization

(2015) Amandine Molliex et al.   CELL

Chemical Biology of Protein Arginine Modifications in Epigenetic Regulation

(2015) Jakob Fuhrmann et al.   CHEMICAL REVIEWS

Jumonji Domain Containing Protein 6: A Novel Oxygen Sensor in the Human Placenta

(2015) Sruthi Alahari et al.   ENDOCRINOLOGY

PRMT1-mediated arginine methylation controls ATXN2L localization

(2015) Christian Kaehler et al.   EXPERIMENTAL CELL RESEARCH

G3BP1 promotes stress-induced RNA granule interactions to preserve polyadenylated mRNA

(2015) Anaïs Aulas et al.   JOURNAL OF CELL BIOLOGY

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins

(2015) Yuan Lin et al.   MOLECULAR CELL

Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles

(2015) Timothy J. Nott et al.   MOLECULAR CELL

A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models

(2015) Elayne Chan-Penebre et al.   Nature Chemical Biology

The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics

(2015) Shana Elbaum-Garfinkle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stress Granules Regulate Double-Stranded RNA-Dependent Protein Kinase Activation through a Complex Containing G3BP1 and Caprin1

(2015) Lucas C. Reineke et al.   mBio

PRMT9 is a Type II methyltransferase that methylates the splicing factor SAP145

(2015) Yanzhong Yang et al.   Nature Communications

JMJD6 Regulates ERα Methylation on Arginine

(2014) Coralie Poulard et al.   PLoS One

Inhibition of mTORC1 by Astrin and Stress Granules Prevents Apoptosis in Cancer Cells

(2013) Kathrin Thedieck et al.   CELL

Localization of SERBP1 in stress granules and nucleoli

(2013) Yu-Jen Lee et al.   FEBS Journal

Stress granules as crucibles of ALS pathogenesis

(2013) Yun R. Li et al.   JOURNAL OF CELL BIOLOGY

Stress granules and cell signaling: more than just a passing phase?

(2013) Nancy Kedersha et al.   TRENDS IN BIOCHEMICAL SCIENCES

Diversion of stress granules and P-bodies during viral infection

(2013) Lucas C. Reineke et al.   VIROLOGY

Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels

(2012) Masato Kato et al.   CELL

Cell-free Formation of RNA Granules: Bound RNAs Identify Features and Components of Cellular Assemblies

(2012) Tina W. Han et al.   CELL

Stress Granules Inhibit Apoptosis by Reducing Reactive Oxygen Species Production

(2012) M. Takahashi et al.   MOLECULAR AND CELLULAR BIOLOGY

Large G3BP-induced granules trigger eIF2α phosphorylation

(2012) Lucas C. Reineke et al.   MOLECULAR BIOLOGY OF THE CELL

Endogenous TDP-43, but not FUS, contributes to stress granule assembly via G3BP

(2012) Anaïs Aulas et al.   Molecular Neurodegeneration

PKCα Binds G3BP2 and Regulates Stress Granule Formation Following Cellular Stress

(2012) Tamae Kobayashi et al.   PLoS One

The Effect of PRMT1-Mediated Arginine Methylation on the Subcellular Localization, Stress Granules, and Detergent-Insoluble Aggregates of FUS/TLS

(2012) Atsushi Yamaguchi et al.   PLoS One

Roles of protein arginine methylation in DNA damage signaling pathways

(2011) Young-Ho Lee et al.   CELL CYCLE

Calcineurin Colocalizes with P-Bodies and Stress Granules during Thermal Stress in Cryptococcus neoformans

(2011) Lukasz Kozubowski et al.   EUKARYOTIC CELL

Arginine methylation by PRMT1 regulates nuclear-cytoplasmic localization and toxicity of FUS/TLS harbouring ALS-linked mutations

(2011) Miranda L. Tradewell et al.   HUMAN MOLECULAR GENETICS

TAR DNA-binding protein 43 (TDP-43) regulates stress granule dynamics via differential regulation of G3BP and TIA-1

(2011) Karli K. McDonald et al.   HUMAN MOLECULAR GENETICS

Arginine methylation of G3BP1 in response to Wnt3a regulates  -catenin mRNA

(2011) R. K. Bikkavilli et al.   JOURNAL OF CELL SCIENCE

A Novel Role for hSMG-1 in Stress Granule Formation

(2011) J. A. L. Brown et al.   MOLECULAR AND CELLULAR BIOLOGY

Poly(ADP-Ribose) Regulates Stress Responses and MicroRNA Activity in the Cytoplasm

(2011) Anthony K.L. Leung et al.   MOLECULAR CELL

Deciphering arginine methylation: Tudor tells the tale

(2011) Chen Chen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Wnt signalling antagonizes stress granule assembly through a Dishevelled-dependent mechanism

(2011) P. K. Sahoo et al.   Biology Open

Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granules

(2010) Daryl A. Bosco et al.   HUMAN MOLECULAR GENETICS

Protein Arginine Methylation in Mammals: Who, What, and Why

(2009) Mark T. Bedford et al.   MOLECULAR CELL

Tdrd3 is a novel stress granule-associated protein interacting with the Fragile-X syndrome protein FMRP

(2008) Bastian Linder et al.   HUMAN MOLECULAR GENETICS

TDRD3, a novel Tudor domain-containing protein, localizes to cytoplasmic stress granules

(2008) I. Goulet et al.   HUMAN MOLECULAR GENETICS

Interaction with 14-3-3 Adaptors Regulates the Sorting of hMex-3B RNA-binding Protein to Distinct Classes of RNA Granules

(2008) Julien Courchet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A role for Q/N-rich aggregation-prone regions in P-body localization

(2008) M. A. M. Reijns et al.   JOURNAL OF CELL SCIENCE

Codependent Functions of RSK2 and the Apoptosis-Promoting Factor TIA-1 in Stress Granule Assembly and Cell Survival

(2008) T.S. Karin Eisinger-Mathason et al.   MOLECULAR CELL

Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways

(2008) Kyoko Arimoto et al.   NATURE CELL BIOLOGY

A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly

(2008) Takbum Ohn et al.   NATURE CELL BIOLOGY

Stress granules: the Tao of RNA triage

(2008) Paul Anderson et al.   TRENDS IN BIOCHEMICAL SCIENCES