Relationships between Stress Granules, Oxidative Stress, and Neurodegenerative Diseases

ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure

(2016) Saumya Jain et al.   CELL

G3BP–Caprin1–USP10 complexes mediate stress granule condensation and associate with 40S subunits

(2016) Nancy Kedersha et al.   JOURNAL OF CELL BIOLOGY

C9ORF72 interaction with cofilin modulates actin dynamics in motor neurons

(2016) Rajeeve Sivadasan et al.   NATURE NEUROSCIENCE

YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression

(2016) Shawn M. Lyons et al.   NUCLEIC ACIDS RESEARCH

Principles and Properties of Stress Granules

(2016) David S.W. Protter et al.   TRENDS IN CELL BIOLOGY

TIA1 oxidation inhibits stress granule assembly and sensitizes cells to stress-induced apoptosis

(2016) Kyoko Arimoto-Matsuzaki et al.   Nature Communications

Distinct stages in stress granule assembly and disassembly

(2016) Joshua R Wheeler et al.   eLife

Stress granules, P-bodies and cancer

(2015) Paul Anderson et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Reversible, Specific, Active Aggregates of Endogenous Proteins Assemble upon Heat Stress

(2015) Edward W.J. Wallace et al.   CELL

Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization

(2015) Amandine Molliex et al.   CELL

YB-1 regulates stress granule formation and tumor progression by translationally activating G3BP1

(2015) Syam Prakash Somasekharan et al.   JOURNAL OF CELL BIOLOGY

G3BP1 promotes stress-induced RNA granule interactions to preserve polyadenylated mRNA

(2015) Anaïs Aulas et al.   JOURNAL OF CELL BIOLOGY

Promiscuous interactions and protein disaggregases determine the material state of stress-inducible RNP granules

(2015) Sonja Kroschwald et al.   eLife

The Role of Oxidative Stress in Neurodegenerative Diseases

(2015) Geon Ha Kim et al.   Experimental Neurobiology

Characterization of a homolog of DEAD-box RNA helicases in Toxoplasma gondii as a marker of cytoplasmic mRNP stress granules

(2014) Ahmed Adnan Cherry et al.   GENE

ALS-Linked Mutations Enlarge TDP-43-Enriched Neuronal RNA Granules in the Dendritic Arbor

(2014) L. Liu-Yesucevitz et al.   JOURNAL OF NEUROSCIENCE

Axonal Transport of TDP-43 mRNA Granules Is Impaired by ALS-Causing Mutations

(2014) Nael H. Alami et al.   NEURON

mRNP granules

(2014) J Ross Buchan   RNA Biology

Stress Granule-Defective Mutants Deregulate Stress Responsive Transcripts

(2014) Xiaoxue Yang et al.   PLoS Genetics

Roles of eIF2α kinases in the pathogenesis of Alzheimer’s disease

(2014) Masuo Ohno   Frontiers in Molecular Neuroscience

Treadmill exercise represses neuronal cell death and inflammation during Aβ-induced ER stress by regulating unfolded protein response in aged presenilin 2 mutant mice

(2013) Eun-Bum Kang et al.   APOPTOSIS

Functional diversity of protein fibrillar aggregates from physiology to RNA granules to neurodegenerative diseases

(2013) Yoshiaki Furukawa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Eukaryotic Stress Granules Are Cleared by Autophagy and Cdc48/VCP Function

(2013) J. Ross Buchan et al.   CELL

Inhibition of mTORC1 by Astrin and Stress Granules Prevents Apoptosis in Cancer Cells

(2013) Kathrin Thedieck et al.   CELL

Altered Ribostasis: RNA-Protein Granules in Degenerative Disorders

(2013) Mani Ramaswami et al.   CELL

Coordination of Translational Control and Protein Homeostasis during Severe Heat Stress

(2013) Valeria Cherkasov et al.   CURRENT BIOLOGY

Role of Stress Granules and RNA-Binding Proteins in Neurodegeneration: A Mini-Review

(2013) Tara Vanderweyde et al.   GERONTOLOGY

Stress granules as crucibles of ALS pathogenesis

(2013) Yun R. Li et al.   JOURNAL OF CELL BIOLOGY

A cellular model for sporadic ALS using patient-derived induced pluripotent stem cells

(2013) Matthew F. Burkhardt et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

HDAC6 as a target for neurodegenerative diseases: what makes it different from the other HDACs?

(2013) Claudia Simões-Pires et al.   Molecular Neurodegeneration

Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS

(2013) Hong Joo Kim et al.   NATURE

Stress granules and cell signaling: more than just a passing phase?

(2013) Nancy Kedersha et al.   TRENDS IN BIOCHEMICAL SCIENCES

Prediction of Functional Loss of Human Angiogenin Mutants Associated with ALS by Molecular Dynamics Simulations

(2013) Aditya K. Padhi et al.   Scientific Reports

Hydrogen peroxide induces stress granule formation independent of eIF2α phosphorylation

(2012) Mohamed M. Emara et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels

(2012) Masato Kato et al.   CELL

Metazoan Hsp70 machines use Hsp110 to power protein disaggregation

(2012) Heike Rampelt et al.   EMBO JOURNAL

Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease

(2012) Nambirajan Govindarajan et al.   EMBO Molecular Medicine

Neurodegeneration-associated TDP-43 Interacts with Fragile X Mental Retardation Protein (FMRP)/Staufen (STAU1) and Regulates SIRT1 Expression in Neuronal Cells

(2012) Zhipeng Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Requirements for Stress Granule Recruitment of Fused in Sarcoma (FUS) and TAR DNA-binding Protein of 43 kDa (TDP-43)

(2012) Eva Bentmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Contrasting Pathology of the Stress Granule Proteins TIA-1 and G3BP in Tauopathies

(2012) T. Vanderweyde et al.   JOURNAL OF NEUROSCIENCE

Stress Granules Inhibit Apoptosis by Reducing Reactive Oxygen Species Production

(2012) M. Takahashi et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulated protein aggregation: stress granules and neurodegeneration

(2012) Benjamin Wolozin   Molecular Neurodegeneration

Sustained translational repression by eIF2α-P mediates prion neurodegeneration

(2012) Julie A. Moreno et al.   NATURE

Global analysis of yeast mRNPs

(2012) Sarah F Mitchell et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Recent Advances in the Treatment of Neurodegenerative Diseases Based on GSH Delivery Systems

(2012) Ivana Cacciatore et al.   Oxidative Medicine and Cellular Longevity

Therapeutic Approach to Neurodegenerative Diseases by Medical Gases: Focusing on Redox Signaling and Related Antioxidant Enzymes

(2012) Kyota Fujita et al.   Oxidative Medicine and Cellular Longevity

Mechanism of Oxidative Stress in Neurodegeneration

(2012) Sonia Gandhi et al.   Oxidative Medicine and Cellular Longevity

Neuronal mRNAs travel singly into dendrites

(2012) M. Batish et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and molecular insights into the mechanism of action of human angiogenin-ALS variants in neurons

(2012) Nethaji Thiyagarajan et al.   Nature Communications

Angiogenin variants in Parkinson disease and amyotrophic lateral sclerosis

(2011) Michael A. van Es et al.   ANNALS OF NEUROLOGY

Critical roles of RNA helicase DDX3 and its interactions with eIF4E/PABP1 in stress granule assembly and stress response

(2011) Jing-Wen Shih et al.   BIOCHEMICAL JOURNAL

TAR DNA-binding protein 43 (TDP-43) regulates stress granule dynamics via differential regulation of G3BP and TIA-1

(2011) Karli K. McDonald et al.   HUMAN MOLECULAR GENETICS

Progranulin and TDP-43: Mechanistic Links and Future Directions

(2011) Samir Kumar-Singh   JOURNAL OF MOLECULAR NEUROSCIENCE

HDAC6 α-tubulin deacetylase: A potential therapeutic target in neurodegenerative diseases

(2011) Guoyi Li et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

A Novel Role for hSMG-1 in Stress Granule Formation

(2011) J. A. L. Brown et al.   MOLECULAR AND CELLULAR BIOLOGY

The DEAD-Box Protein Ded1 Modulates Translation by the Formation and Resolution of an eIF4F-mRNA Complex

(2011) Angela Hilliker et al.   MOLECULAR CELL

HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1–induced Charcot-Marie-Tooth disease

(2011) Constantin d'Ydewalle et al.   NATURE MEDICINE

Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS

(2011) Mariely DeJesus-Hernandez et al.   NEURON

The Mammalian Disaggregase Machinery: Hsp110 Synergizes with Hsp70 and Hsp40 to Catalyze Protein Disaggregation and Reactivation in a Cell-Free System

(2011) James Shorter   PLoS One

The Ataxin-2 protein is required for microRNA function and synapse-specific long-term olfactory habituation

(2011) C. McCann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulation of Tau Phosphorylation by the Kinase PKR: Implications in Alzheimer's Disease

(2010) Anindita Bose et al.   BRAIN PATHOLOGY

Depletion of GSH in glial cells induces neurotoxicity: relevance to aging and degenerative neurological diseases

(2010) Moonhee Lee et al.   FASEB JOURNAL

Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granules

(2010) Daryl A. Bosco et al.   HUMAN MOLECULAR GENETICS

Angiogenin-induced tRNA-derived Stress-induced RNAs Promote Stress-induced Stress Granule Assembly

(2010) Mohamed M. Emara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plakophilin 1 stimulates translation by promoting eIF4A1 activity

(2010) Annika Wolf et al.   JOURNAL OF CELL BIOLOGY

Stress-specific composition, assembly and kinetics of stress granules in Saccharomyces cerevisiae

(2010) J. R. Buchan et al.   JOURNAL OF CELL SCIENCE

Modulation of Stress Granules and P Bodies during Dicistrovirus Infection

(2010) A. Khong et al.   JOURNAL OF VIROLOGY

Stable Formation of Compositionally Unique Stress Granules in Virus-Infected Cells

(2010) J. Piotrowska et al.   JOURNAL OF VIROLOGY

Amyotrophic lateral sclerosis and frontotemporal lobar degeneration: A spectrum of TDP-43 proteinopathies

(2010) Felix Geser et al.   NEUROPATHOLOGY

Tar DNA Binding Protein-43 (TDP-43) Associates with Stress Granules: Analysis of Cultured Cells and Pathological Brain Tissue

(2010) Liqun Liu-Yesucevitz et al.   PLoS One

Defining the Human Deubiquitinating Enzyme Interaction Landscape

(2009) Mathew E. Sowa et al.   CELL

Oxidative Stress Increases the Number of Stress Granules in Senescent Cells and Triggers a Rapid Decrease in p21waf1/cip1Translation

(2009) Xian Jin Lian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucose deprivation-induced metabolic oxidative stress and cancer therapy

(2009) DouglasR Spitz et al.   Journal of Cancer Research and Therapeutics

Angiogenin cleaves tRNA and promotes stress-induced translational repression

(2009) Satoshi Yamasaki et al.   JOURNAL OF CELL BIOLOGY

Unravelling the ultrastructure of stress granules and associated P-bodies in human cells

(2009) S. Souquere et al.   JOURNAL OF CELL SCIENCE

Cross-Seeding Fibrillation of Q/N-Rich Proteins Offers New Pathomechanism of Polyglutamine Diseases

(2009) Y. Furukawa et al.   JOURNAL OF NEUROSCIENCE

Eukaryotic Stress Granules: The Ins and Outs of Translation

(2009) J. Ross Buchan et al.   MOLECULAR CELL

P bodies promote stress granule assembly inSaccharomyces cerevisiae

(2008) J. Ross Buchan et al.   JOURNAL OF CELL BIOLOGY

Protein:protein aggregation induced by protein oxidation

(2008) Hamid Mirzaei et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Histone deacetylase 6 interacts with the microtubule-associated protein tau

(2008) Huiping Ding et al.   JOURNAL OF NEUROCHEMISTRY

Direct Binding with Histone Deacetylase 6 Mediates the Reversible Recruitment of Parkin to the Centrosome

(2008) Q. Jiang et al.   JOURNAL OF NEUROSCIENCE

Translationally Repressed mRNA Transiently Cycles through Stress Granules during Stress

(2008) Stephanie Mollet et al.   MOLECULAR BIOLOGY OF THE CELL

HDAC6 is a specific deacetylase of peroxiredoxins and is involved in redox regulation

(2008) R. B. Parmigiani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA