N-terminal sequences in matrin 3 mediate phase separation into droplet-like structures that recruit TDP43 variants lacking RNA binding elements

The p.S85C-mutation in MATR3 impairs stress granule formation in Matrin-3 myopathy

(2018) Alexander Mensch et al.   EXPERIMENTAL NEUROLOGY

RNA buffers the phase separation behavior of prion-like RNA binding proteins

(2018) Shovamayee Maharana et al.   SCIENCE

Paraspeckles: Where Long Noncoding RNA Meets Phase Separation

(2018) Archa H. Fox et al.   TRENDS IN BIOCHEMICAL SCIENCES

Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy

(2018) M. Carolina Gallego Iradi et al.   Scientific Reports

Matrin 3-dependent neurotoxicity is modified by nucleic acid binding and nucleocytoplasmic localization

(2018) Ahmed M Malik et al.   eLife

Linking hnRNP Function to ALS and FTD Pathology

(2018) Maria D. Purice et al.   Frontiers in Neuroscience

Analysis of spinal and muscle pathology in transgenic mice overexpressing wild-type and ALS-linked mutant MATR3

(2018) Christina Moloney et al.   Acta Neuropathologica Communications

Matrin 3 variants are frequent in Italian ALS patients

(2017) Giuseppe Marangi et al.   NEUROBIOLOGY OF AGING

ALS Associated Mutations in Matrin 3 Alter Protein-Protein Interactions and Impede mRNA Nuclear Export

(2017) Ashley Boehringer et al.   Scientific Reports

Prion-like domains as epigenetic regulators, scaffolds for subcellular organization, and drivers of neurodegenerative disease

(2016) Zachary M. March et al.   BRAIN RESEARCH

Replication study of MATR3 in familial and sporadic amyotrophic lateral sclerosis

(2016) Claire S. Leblond et al.   NEUROBIOLOGY OF AGING

In Vivo Formation of Vacuolated Multi-phase Compartments Lacking Membranes

(2016) Hermann Broder Schmidt et al.   Cell Reports

Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization

(2015) Amandine Molliex et al.   CELL

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation

(2015) Avinash Patel et al.   CELL

Nuclear matrix protein Matrin3 regulates alternative splicing and forms overlapping regulatory networks with PTB

(2015) M. B. Coelho et al.   EMBO JOURNAL

Compartmentalization and Functionality of Nuclear Disorder: Intrinsic Disorder and Protein-Protein Interactions in Intra-Nuclear Compartments

(2015) Fanchi Meng et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Re-evaluation of the phenotype caused by the commonMATR3p.Ser85Cys mutation in a new family

(2015) Johanna Palmio et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Re-Opening the Critical Window for Estrogen Therapy

(2015) L. A. Bean et al.   JOURNAL OF NEUROSCIENCE

It’s Raining Liquids: RNA Tunes Viscoelasticity and Dynamics of Membraneless Organelles

(2015) Lin Guo et al.   MOLECULAR CELL

Mutational analysis of MATR3 in Taiwanese patients with amyotrophic lateral sclerosis

(2015) Kon-Ping Lin et al.   NEUROBIOLOGY OF AGING

Alterations in stress granule dynamics driven by TDP-43 and FUS: a link to pathological inclusions in ALS?

(2015) Anaïs Aulas et al.   Frontiers in Cellular Neuroscience

Subcellular Localization of Matrin 3 Containing Mutations Associated with ALS and Distal Myopathy

(2015) M. Carolina Gallego-Iradi et al.   PLoS One

Phenotype of matrin-3-related distal myopathy in 16 German patients

(2014) Tobias J. Müller et al.   ANNALS OF NEUROLOGY

Intrinsically disordered proteins as crucial constituents of cellular aqueous two phase systems and coacervates

(2014) Vladimir N. Uversky et al.   FEBS LETTERS

Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis

(2014) Janel O Johnson et al.   NATURE NEUROSCIENCE

Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS

(2013) Hong Joo Kim et al.   NATURE

The biophysics and cell biology of lipid droplets

(2013) Abdou Rachid Thiam et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Matrin 3 Binds and Stabilizes mRNA

(2011) Maayan Salton et al.   PLoS One

The proteins of intra-nuclear bodies: a data-driven analysis of sequence, interaction and expression

(2010) Nurul Mohamad et al.   BMC Systems Biology

ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS

(2010) S.-C. Ling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autosomal-Dominant Distal Myopathy Associated with a Recurrent Missense Mutation in the Gene Encoding the Nuclear Matrix Protein, Matrin 3

(2009) Jan Senderek et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation

(2009) C. P. Brangwynne et al.   SCIENCE