Quantitative bioimage analytics enables measurement of targeted cellular stress response induced by celastrol-loaded nanoparticles

Sugar-decorated mesoporous silica nanoparticles as delivery vehicles for the poorly soluble drug celastrol enables targeted induction of apoptosis in cancer cells

(2015) Erik Niemelä et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Unexpected low-dose toxicity of the universal solvent DMSO

(2013) Joana Galvao et al.   FASEB JOURNAL

Amyotrophic lateral sclerosis-linked FUS/TLS alters stress granule assembly and dynamics

(2013) Desiree M Baron et al.   Molecular Neurodegeneration

Transcriptional response to stress in the dynamic chromatin environment of cycling and mitotic cells

(2013) Anniina Vihervaara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HSF1 Drives a Transcriptional Program Distinct from Heat Shock to Support Highly Malignant Human Cancers

(2012) Marc L. Mendillo et al.   CELL

Canonical Transient Receptor Potential Channel 2 (TRPC2) as a Major Regulator of Calcium Homeostasis in Rat Thyroid FRTL-5 Cells

(2012) Pramod Sukumaran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Why bioimage informatics matters

(2012) Gene Myers   NATURE METHODS

BioImageXD: an open, general-purpose and high-throughput image-processing platform

(2012) Pasi Kankaanpää et al.   NATURE METHODS

A call for bioimaging software usability

(2012) Anne E Carpenter et al.   NATURE METHODS

Current challenges in open-source bioimage informatics

(2012) Albert Cardona et al.   NATURE METHODS

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

(2011) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Targeted drug delivery to tumors: Myths, reality and possibility

(2011) You Han Bae et al.   JOURNAL OF CONTROLLED RELEASE

Celastrol: Molecular targets of Thunder God Vine

(2010) Antero Salminen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Towards multifunctional, targeted drug delivery systems using mesoporous silica nanoparticles – opportunities & challenges

(2010) Jessica M. Rosenholm et al.   Nanoscale

Heat shock factors: integrators of cell stress, development and lifespan

(2010) Malin Åkerfelt et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Natural Product Celastrol Destabilizes Tubulin Heterodimer and Facilitates Mitotic Cell Death Triggered by Microtubule-Targeting Anti-Cancer Drugs

(2010) Hakryul Jo et al.   PLoS One

Nuclear Stress Bodies

(2010) G. Biamonti et al.   Cold Spring Harbor Perspectives in Biology

Nanoparticle-based targeted drug delivery

(2009) Rajesh Singh et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Heterotrimerization of Heat-Shock Factors 1 and 2 Provides a Transcriptional Switch in Response to Distinct Stimuli

(2009) Anton Sandqvist et al.   MOLECULAR BIOLOGY OF THE CELL

Stress-Inducible Regulation of Heat Shock Factor 1 by the Deacetylase SIRT1

(2009) S. D. Westerheide et al.   SCIENCE

Targeting of Porous Hybrid Silica Nanoparticles to Cancer Cells

(2008) Jessica M. Rosenholm et al.   ACS Nano

Apoptosis and necrosis: Detection, discrimination and phagocytosis

(2008) Dmitri V. Krysko et al.   METHODS

Activation of Heat Shock and Antioxidant Responses by the Natural Product Celastrol: Transcriptional Signatures of a Thiol-targeted Molecule

(2008) Amy Trott et al.   MOLECULAR BIOLOGY OF THE CELL

A Raft-derived, Pak1-regulated Entry Participates in α2β1 Integrin-dependent Sorting to Caveosomes

(2008) Mikko Karjalainen et al.   MOLECULAR BIOLOGY OF THE CELL

Hyperbranching Surface Polymerization as a Tool for Preferential Functionalization of the Outer Surface of Mesoporous Silica†

(2007) Jessica M. Rosenholm et al.   CHEMISTRY OF MATERIALS