Brain Insulin Resistance and Hippocampal Plasticity: Mechanisms and Biomarkers of Cognitive Decline
出版年份 2019 全文链接
标题
Brain Insulin Resistance and Hippocampal Plasticity: Mechanisms and Biomarkers of Cognitive Decline
作者
关键词
-
出版物
Frontiers in Neuroscience
Volume 13, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2019-07-31
DOI
10.3389/fnins.2019.00788
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Impact of Caffeine Consumption on Type 2 Diabetes-Induced Spatial Memory Impairment and Neurochemical Alterations in the Hippocampus
- (2019) João M. N. Duarte et al. Frontiers in Neuroscience
- Outcomes and clinical implications of intranasal insulin administration to the central nervous system
- (2019) João C.P. Santiago et al. EXPERIMENTAL NEUROLOGY
- The Medial Septum Is Insulin Resistant in the AD Presymptomatic Phase: Rescue by Nerve Growth Factor-Driven IRS1 Activation
- (2018) Valentina Sposato et al. MOLECULAR NEUROBIOLOGY
- Intranasal insulin in Alzheimer's disease: Food for thought
- (2018) Colin D. Chapman et al. NEUROPHARMACOLOGY
- Pro- and Anti-inflammatory Effects of High Cholesterol Diet on Aged Brain
- (2018) Yali Chen et al. Aging and Disease
- Obesity, Cognitive Functioning and Dementia: Back to the Future
- (2018) Merrill F. Elias et al. JOURNAL OF ALZHEIMERS DISEASE
- Cognitive Function and Decline in Obesity
- (2018) Kelly Stanek Sellbom et al. JOURNAL OF ALZHEIMERS DISEASE
- Type 2 diabetes mellitus, brain atrophy and cognitive decline in older people: a longitudinal study
- (2018) Michele L. Callisaya et al. DIABETOLOGIA
- High fat diet increases cognitive decline and neuroinflammation in a model of orexin loss
- (2018) C.M. Duffy et al. NEUROBIOLOGY OF LEARNING AND MEMORY
- Exosomal biomarkers of brain insulin resistance associated with regional atrophy in Alzheimer's disease
- (2017) Roger J. Mullins et al. HUMAN BRAIN MAPPING
- Effects of Regular and Long-Acting Insulin on Cognition and Alzheimer’s Disease Biomarkers: A Pilot Clinical Trial
- (2017) Suzanne Craft et al. JOURNAL OF ALZHEIMERS DISEASE
- Neuroprotective astrocyte-derived insulin/insulin-like growth factor 1 stimulates endocytic processing and extracellular release of neuron-bound Aβ oligomers
- (2017) Jason Pitt et al. MOLECULAR BIOLOGY OF THE CELL
- Alterations of Brain Energy Metabolism in Type 2 Diabetic Goto-Kakizaki Rats Measured In Vivo by 13C Magnetic Resonance Spectroscopy
- (2017) Freya-Merret Girault et al. NEUROTOXICITY RESEARCH
- Insulin-Like Growth Factor (IGF) Binding Protein-2, Independently of IGF-1, Induces GLUT-4 Translocation and Glucose Uptake in 3T3-L1 Adipocytes
- (2017) Biruhalem Assefa et al. Oxidative Medicine and Cellular Longevity
- Loss of Leptin-Induced Modulation of Hippocampal Synaptic Trasmission and Signal Transduction in High-Fat Diet-Fed Mice
- (2017) Marco Mainardi et al. Frontiers in Cellular Neuroscience
- Brain insulin resistance impairs hippocampal synaptic plasticity and memory by increasing GluA1 palmitoylation through FoxO3a
- (2017) Matteo Spinelli et al. Nature Communications
- Intranasal Insulin Administration Dose-Dependently Modulates Verbal Memory and Plasma Amyloid-β in Memory-Impaired Older Adults
- (2017) Mark A. Reger et al. JOURNAL OF ALZHEIMERS DISEASE
- Communication by Extracellular Vesicles: Where We Are and Where We Need to Go
- (2016) Mercedes Tkach et al. CELL
- Dementia onset, incidence and risk in type 2 diabetes: a matched cohort study with the Fremantle Diabetes Study Phase I
- (2016) Wendy A. Davis et al. DIABETOLOGIA
- Cargo proteins of plasma astrocyte-derived exosomes in Alzheimer’s disease
- (2016) Edward J. Goetzl et al. FASEB JOURNAL
- Animal models of metabolic syndrome: a review
- (2016) Sok Kuan Wong et al. Nutrition & Metabolism
- Brain Insulin Resistance at the Crossroads of Metabolic and Cognitive Disorders in Humans
- (2016) Stephanie Kullmann et al. PHYSIOLOGICAL REVIEWS
- A CREB-Sirt1-Hes1 Circuitry Mediates Neural Stem Cell Response to Glucose Availability
- (2016) Salvatore Fusco et al. Cell Reports
- Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study
- (2015) Massimo S. Fiandaca et al. Alzheimers & Dementia
- Impact of diabetes on cognitive function and brain structure
- (2015) Amir Moheet et al. Annals of the New York Academy of Sciences
- Hippocampal Insulin Resistance Impairs Spatial Learning and Synaptic Plasticity
- (2015) Claudia A. Grillo et al. DIABETES
- Type 2 Diabetes as a Risk Factor for Dementia in Women Compared With Men: A Pooled Analysis of 2.3 Million People Comprising More Than 100,000 Cases of Dementia
- (2015) Saion Chatterjee et al. DIABETES CARE
- Clinically Relevant Cognitive Impairment in Middle-Aged Adults With Childhood-Onset Type 1 Diabetes
- (2015) Karen A. Nunley et al. DIABETES CARE
- Dysfunctionally phosphorylated type 1 insulin receptor substrate in neural-derived blood exosomes of preclinical Alzheimer’s disease
- (2015) Dimitrios Kapogiannis et al. FASEB JOURNAL
- Reduced Uptake of 18F-FDG and 15O-H2O in Alzheimer'S Disease-Related Regions after Glucose Loading
- (2015) Kenji Ishibashi et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Alteration of mTOR signaling occurs early in the progression of Alzheimer disease (AD): analysis of brain from subjects with pre-clinical AD, amnestic mild cognitive impairment and late-stage AD
- (2015) Antonella Tramutola et al. JOURNAL OF NEUROCHEMISTRY
- Type 2 diabetes mellitus and biomarkers of neurodegeneration
- (2015) Chris Moran et al. NEUROLOGY
- The hippocampus in aging and disease: From plasticity to vulnerability
- (2015) T. Bartsch et al. NEUROSCIENCE
- Insulin resistance in brain alters dopamine turnover and causes behavioral disorders
- (2015) Andre Kleinridders et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Modulation of Hippocampal Neural Plasticity by Glucose-Related Signaling
- (2015) Marco Mainardi et al. NEURAL PLASTICITY
- Aberrant insulin signaling in Alzheimer's disease: current knowledge
- (2015) Gaurav Bedse et al. Frontiers in Neuroscience
- Insulin can induce the expression of a memory-related synaptic protein through facilitating AMPA receptor endocytosis in rat cortical neurons
- (2014) Tsan-Ju Chen et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- SIRT1 suppresses self-renewal of adult hippocampal neural stem cells
- (2014) C.-y. Ma et al. DEVELOPMENT
- Adult neurogenesis: mechanisms and functional significance
- (2014) S. M. G. Braun et al. DEVELOPMENT
- Repurposing Diabetes Drugs for Brain Insulin Resistance in Alzheimer Disease
- (2014) M. Yarchoan et al. DIABETES
- Association Between Polymorphisms of the Insulin-Degrading Enzyme Gene and Late-Onset Alzheimer Disease
- (2014) Shitao Wang et al. JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY
- Insulin induces phosphorylation of the AMPA receptor subunit GluR1, reversed by ZIP, and over-expression of Protein Kinase M zeta, reversed by amyloid beta
- (2014) Linda Adzovic et al. JOURNAL OF NEUROCHEMISTRY
- Early detection of Alzheimer's disease using PiB and FDG PET
- (2014) Ann D. Cohen et al. NEUROBIOLOGY OF DISEASE
- High fat diet produces brain insulin resistance, synaptodendritic abnormalities and altered behavior in mice
- (2014) Steven E. Arnold et al. NEUROBIOLOGY OF DISEASE
- Chronic Functional Bowel Syndrome Enhances Gut-Brain Axis Dysfunction, Neuroinflammation, Cognitive Impairment, and Vulnerability to Dementia
- (2014) Mak Adam Daulatzai NEUROCHEMICAL RESEARCH
- Blood-brain barrier disruption: mechanistic links between Western diet consumption and dementia
- (2014) Ted M. Hsu et al. Frontiers in Aging Neuroscience
- Evidence for altered transport of insulin across the blood–brain barrier in insulin-resistant humans
- (2013) Martin Heni et al. ACTA DIABETOLOGICA
- Activation of sirtuin 1 attenuates cerebral ventricular streptozotocin-induced tau hyperphosphorylation and cognitive injuries in rat hippocampi
- (2013) Lai-Ling Du et al. AGE
- Calorie restriction alleviates the age-related decrease in neural progenitor cell division in the aging brain
- (2013) June-Hee Park et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Insulin, cognition, and dementia
- (2013) Brenna Cholerton et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- SIRT1 regulates the neurogenic potential of neural precursors in the adult subventricular zone and hippocampus
- (2013) Sumiti Saharan et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Higher glucose levels associated with lower memory and reduced hippocampal microstructure
- (2013) L. Kerti et al. NEUROLOGY
- Glucose Levels and Risk of Dementia
- (2013) NEW ENGLAND JOURNAL OF MEDICINE
- The therapeutic potential of endogenous hippocampal stem cells for the treatment of neurological disorders
- (2013) Chanel J. Taylor et al. Frontiers in Cellular Neuroscience
- Diabetes mellitus and risk of dementia: A meta-analysis of prospective observational studies
- (2013) Kapil Gudala et al. Journal of Diabetes Investigation
- Hyperinsulinemia in rats causes impairment of spatial memory and learning with defects in hippocampal synaptic plasticity by involvement of postsynaptic mechanisms
- (2013) Amer Kamal et al. EXPERIMENTAL BRAIN RESEARCH
- Systematic review of the body of evidence for the use of biomarkers in the diagnosis of dementia
- (2012) Anna H. Noel-Storr et al. Alzheimers & Dementia
- Fueling and Imaging Brain Activation
- (2012) Gerald A Dienel ASN Neuro
- Ghrelin Signaling in the Ventral Hippocampus Stimulates Learned and Motivational Aspects of Feeding via PI3K-Akt Signaling
- (2012) Scott E. Kanoski et al. BIOLOGICAL PSYCHIATRY
- Sirt1: Def-eating senescence?
- (2012) Salvatore Fusco et al. CELL CYCLE
- Brain response to calorie restriction
- (2012) Salvatore Fusco et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Neuronal autophagy and neurodegenerative diseases
- (2012) Jin H. Son et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Juvenile, but not adult exposure to high-fat diet impairs relational memory and hippocampal neurogenesis in mice
- (2012) Chloe Boitard et al. HIPPOCAMPUS
- Updated Energy Budgets for Neural Computation in the Neocortex and Cerebellum
- (2012) Clare Howarth et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline
- (2012) Konrad Talbot et al. JOURNAL OF CLINICAL INVESTIGATION
- The many faces of insulin-like peptide signalling in the brain
- (2012) Ana M. Fernandez et al. NATURE REVIEWS NEUROSCIENCE
- Insulin Receptor β-Subunit Haploinsufficiency Impairs Hippocampal Late-Phase LTP and Recognition Memory
- (2012) Robert Nisticò et al. NEUROMOLECULAR MEDICINE
- Vascular β-amyloid and early astrocyte alterations impair cerebrovascular function and cerebral metabolism in transgenic arcAβ mice
- (2011) Mario Merlini et al. ACTA NEUROPATHOLOGICA
- The association between systemic inflammation and cognitive performance in the elderly: the Sydney Memory and Ageing Study
- (2011) Julian N. Trollor et al. AGE
- Sustained Activation of mTOR Pathway in Embryonic Neural Stem Cells Leads to Development of Tuberous Sclerosis Complex-Associated Lesions
- (2011) Laura Magri et al. Cell Stem Cell
- IRS-2 Deficiency Impairs NMDA Receptor-Dependent Long-term Potentiation
- (2011) Eduardo D. Martín et al. CEREBRAL CORTEX
- Insulin sensitivity of the human brain
- (2011) Caroline Ketterer et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Insulin biosynthesis in neuronal progenitors derived from adult hippocampus and the olfactory bulb
- (2011) Tomoko Kuwabara et al. EMBO Molecular Medicine
- Vascular Changes in Rat Hippocampus following a High Saturated Fat and Cholesterol Diet
- (2011) Linnea R Freeman et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Insulin receptor substrate 2 is a negative regulator of memory formation
- (2011) E. E. Irvine et al. LEARNING & MEMORY
- Fat cells reactivate quiescent neuroblasts via TOR and glial insulin relays in Drosophila
- (2011) Rita Sousa-Nunes et al. NATURE
- Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway
- (2011) Hyunkyung Jeong et al. NATURE MEDICINE
- CREB and the CRTC co-activators: sensors for hormonal and metabolic signals
- (2011) Judith Y. Altarejos et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Insulin promotes dendritic spine and synapse formation by the PI3K/Akt/mTOR and Rac1 signaling pathways
- (2011) Cheng-Che Lee et al. NEUROPHARMACOLOGY
- Insulin Promotes Glycogen Storage and Cell Proliferation in Primary Human Astrocytes
- (2011) Martin Heni et al. PLoS One
- A role for neuronal cAMP responsive-element binding (CREB)-1 in brain responses to calorie restriction
- (2011) S. Fusco et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Selective pharmacogenetic inhibition of mammalian target of Rapamycin complex I (mTORC1) blocks long-term synaptic plasticity and memory storage
- (2011) Loredana Stoica et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- When is adult hippocampal neurogenesis necessary for learning? Evidence from animal research
- (2011) Estela Castilla-Ortega et al. REVIEWS IN THE NEUROSCIENCES
- Vascular Contributions to Cognitive Impairment and Dementia
- (2011) Philip B. Gorelick et al. STROKE
- Insulin Resistance and Alzheimer-like Reductions in Regional Cerebral Glucose Metabolism for Cognitively Normal Adults With Prediabetes or Early Type 2 Diabetes
- (2010) Laura D. Baker et al. ARCHIVES OF NEUROLOGY
- Nutrition-Responsive Glia Control Exit of Neural Stem Cells from Quiescence
- (2010) James M. Chell et al. CELL
- Different patterns of memory impairments accompany short- and longer-term maintenance on a high-energy diet.
- (2010) Scott E. Kanoski et al. JOURNAL OF EXPERIMENTAL PSYCHOLOGY-ANIMAL LEARNING AND COGNITION
- Diabetes-Associated SorCS1 Regulates Alzheimer's Amyloid- Metabolism: Evidence for Involvement of SorL1 and the Retromer Complex
- (2010) R. F. Lane et al. JOURNAL OF NEUROSCIENCE
- Disrupted energy metabolism and neuronal circuit dysfunction in cognitive impairment and Alzheimer's disease
- (2010) Dimitrios Kapogiannis et al. LANCET NEUROLOGY
- The hippocampus in major depression: evidence for the convergence of the bench and bedside in psychiatric research?
- (2010) G MacQueen et al. MOLECULAR PSYCHIATRY
- Hippocampal memory processes are modulated by insulin and high-fat-induced insulin resistance
- (2010) Ewan C. McNay et al. NEUROBIOLOGY OF LEARNING AND MEMORY
- Hippocampal long-term depression is required for the consolidation of spatial memory
- (2010) Y. Ge et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- FoxO3 Regulates Neural Stem Cell Homeostasis
- (2009) Valérie M. Renault et al. Cell Stem Cell
- Insulin Receptor Isoforms and Insulin Receptor/Insulin-Like Growth Factor Receptor Hybrids in Physiology and Disease
- (2009) Antonino Belfiore et al. ENDOCRINE REVIEWS
- Deterioration of physical performance and cognitive function in rats with short-term high-fat feeding
- (2009) Andrew J. Murray et al. FASEB JOURNAL
- Blockade of insulin-like growth factor-I has complex effects on structural plasticity in the hippocampus
- (2009) Erica R. Glasper et al. HIPPOCAMPUS
- Enhanced NMDA Receptor-Mediated Synaptic Transmission, Enhanced Long-Term Potentiation, and Impaired Learning and Memory in Mice Lacking IRSp53
- (2009) M.-H. Kim et al. JOURNAL OF NEUROSCIENCE
- Analgesic, learning and memory and anxiolytic effects of insulin in mice
- (2008) Moses A. Akanmu et al. BEHAVIOURAL BRAIN RESEARCH
- Cognitive Dysfunction and Diabetes Mellitus
- (2008) Christopher T. Kodl et al. ENDOCRINE REVIEWS
- Inhibition of γ-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes
- (2008) Robyn A. Sharples et al. FASEB JOURNAL
- Diet-induced insulin resistance impairs hippocampal synaptic plasticity and cognition in middle-aged rats
- (2008) Alexis M. Stranahan et al. HIPPOCAMPUS
- High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice
- (2008) Lakshmi Thirumangalakudi et al. JOURNAL OF NEUROCHEMISTRY
- Sirt1 contributes critically to the redox-dependent fate of neural progenitors
- (2008) Timour Prozorovski et al. NATURE CELL BIOLOGY
- Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons
- (2008) Alexis M Stranahan et al. NATURE NEUROSCIENCE
- Effects of triglycerides, obesity, and starvation on ghrelin transport across the blood–brain barrier
- (2008) William A. Banks et al. PEPTIDES
- Genetic variant in the glucose transporter type 2 is associated with higher intakes of sugars in two distinct populations
- (2008) Karen M. Eny et al. PHYSIOLOGICAL GENOMICS
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