Nutritional Modulation of Immune and Central Nervous System Homeostasis: The Role of Diet in Development of Neuroinflammation and Neurological Disease

Vitamin D Supplementation in Central Nervous System Demyelinating Disease—Enough Is Enough

(2019) Darius Häusler et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Therapeutic Effect of Agmatine on Neurological Disease: Focus on Ion Channels and Receptors

(2019) Sumit Barua et al.   NEUROCHEMICAL RESEARCH

Metabolomics and Microbiomes as Potential Tools to Evaluate the Effects of the Mediterranean Diet

(2019) Qi Jin et al.   Nutrients

Dietary Vitamin E as a Protective Factor for Parkinson's Disease: Clinical and Experimental Evidence

(2019) Tommaso Schirinzi et al.   Frontiers in Neurology

Shaping the Infant Microbiome With Non-digestible Carbohydrates

(2019) Stella Verkhnyatskaya et al.   Frontiers in Microbiology

The Mediterranean Diet: From an Environment-Driven Food Culture to an Emerging Medical Prescription

(2019) Cristina-Mihaela Lăcătușu et al.   International Journal of Environmental Research and Public Health

Identification of the novel role of butyrate as AhR ligand in human intestinal epithelial cells

(2019) Ludovica Marinelli et al.   Scientific Reports

Absence of gut microbiota during early life affects anxiolytic Behaviors and monoamine neurotransmitters system in the hippocampal of mice

(2019) Jun-Xi Pan et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

The Alternate Consumption of Quercetin and Alliin in the Traditional Asian Diet Reshaped Microbiota and Altered Gene Expression of Colonic Epithelial Cells in Rats

(2019) Juntong Yu et al.   JOURNAL OF FOOD SCIENCE

Glutamatergic Signaling Along The Microbiota-Gut-Brain Axis

(2019) Andreina Baj et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Niacin in the Central Nervous System: An Update of Biological Aspects and Clinical Applications

(2019) Valeria Gasperi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effects of dietary fat on gut microbiota and faecal metabolites, and their relationship with cardiometabolic risk factors: a 6-month randomised controlled-feeding trial

(2019) Yi Wan et al.   GUT

The gut microbiota promotes the pathogenesis of schizophrenia via multiple pathways

(2019) Xiuxia Yuan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Taurine protects noradrenergic locus coeruleus neurons in a mouse Parkinson’s disease model by inhibiting microglial M1 polarization

(2018) Liyan Hou et al.   AMINO ACIDS

Wernicke-Korsakoff syndrome complicated by subacute beriberi neuropathy in an alcoholic patient

(2018) Salvatore Di Marco et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Neuroprotective effect of agmatine (decarboxylated l-arginine) against oxidative stress and neuroinflammation in rotenone model of Parkinson’s disease

(2018) E K El-Sayed et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Association of total zinc, iron, copper and selenium intakes with depression in the US adults

(2018) Zongyao Li et al.   JOURNAL OF AFFECTIVE DISORDERS

Vitamin K1 and Vitamin K2 immunopharmacological effects on the peripheral lymphocytes of healthy subjects and dialysis patients, as estimated by the lymphocyte immunosuppressant sensitivity test

(2018) Junichi Kusano et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Mind-altering with the gut: Modulation of the gut-brain axis with probiotics

(2018) Namhee Kim et al.   JOURNAL OF MICROBIOLOGY

Overexpression of aryl hydrocarbon receptor (AHR) signalling pathway in human meningioma

(2018) Noble Kumar Talari et al.   JOURNAL OF NEURO-ONCOLOGY

Vitamin K1 inversely correlates with glycemia and insulin resistance in patients with type 2 diabetes (T2D) and positively regulates SIRT1/AMPK pathway of glucose metabolism in liver of T2D mice and hepatocytes cultured in high glucose

(2018) Anjum Dihingia et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Vitamin A deficiency in mice alters host and gut microbial metabolism leading to altered energy homeostasis

(2018) Yuan Tian et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Gut Microbiota in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis: Current Applications and Future Perspectives

(2018) Fengna Chu et al.   MEDIATORS OF INFLAMMATION

Folic Acid Improves the Inflammatory Response in LPS-Activated THP-1 Macrophages

(2018) Mirian Samblas et al.   MEDIATORS OF INFLAMMATION

Is there a Link between Vitamin B and Multiple Sclerosis?

(2018) Natalie Nemazannikova et al.   Medicinal Chemistry

Gut microbiota modulate neurobehavior through changes in brain insulin sensitivity and metabolism

(2018) Marion Soto et al.   MOLECULAR PSYCHIATRY

Microglial control of astrocytes in response to microbial metabolites

(2018) Veit Rothhammer et al.   NATURE

AHR signaling in the development and function of intestinal immune cells and beyond

(2018) Luisa Cervantes-Barragan et al.   Seminars in Immunopathology

Vitamin K Antagonists and Cognitive Decline in Older Adults: A 24-Month Follow-Up

(2018) Antoine Brangier et al.   Nutrients

Vitamin C Fosters the In Vivo Differentiation of Peripheral CD4+ Foxp3− T Cells into CD4+ Foxp3+ Regulatory T Cells but Impairs Their Ability to Prolong Skin Allograft Survival

(2018) Karina Oyarce et al.   Frontiers in Immunology

High-protein diets for weight management: Interactions with the intestinal microbiota and consequences for gut health. A position paper by the my new gut study group

(2018) François Blachier et al.   CLINICAL NUTRITION

Diet quality in persons with and without depressive and anxiety disorders

(2018) Deborah Gibson-Smith et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Relevance of gutmicrobiota in cognition, behaviour and Alzheimer’s disease

(2018) Vanessa de J.R. De-Paula et al.   PHARMACOLOGICAL RESEARCH

Selenium, Selenoproteins, and Immunity

(2018) Joseph Avery et al.   Nutrients

The Synergy of Aging and LPS Exposure in a Mouse Model of Parkinson’s Disease

(2018) Yong-Fei Zhao et al.   Aging and Disease

Brain Kynurenine and BH4 Pathways: Relevance to the Pathophysiology and Treatment of Inflammation-Driven Depressive Symptoms

(2018) Sylvie Vancassel et al.   Frontiers in Neuroscience

One-Year Consumption of a Mediterranean-Like Dietary Pattern With Vitamin D3 Supplements Induced Small Scale but Extensive Changes of Immune Cell Phenotype, Co-receptor Expression and Innate Immune Responses in Healthy Elderly Subjects: Results From the United Kingdom Arm of the NU-AGE Trial

(2018) Monica Maijo et al.   Frontiers in Physiology

Short-chain fatty acids and gut microbiota in multiple sclerosis

(2018) Pernille Melbye et al.   ACTA NEUROLOGICA SCANDINAVICA

Dietary fat, the gut microbiota, and metabolic health – A systematic review conducted within the MyNewGut project

(2018) Maike Wolters et al.   CLINICAL NUTRITION

Blood Thiamine Level and Cognitive Function in Older Hospitalized Patients

(2018) Maryam Pourhassan et al.   JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY

Gut Microbiome Dysbiosis and Immunometabolism: New Frontiers for Treatment of Metabolic Diseases

(2018) José E. Belizário et al.   MEDIATORS OF INFLAMMATION

Polygenic disruption of retinoid signalling in schizophrenia and a severe cognitive deficit subtype

(2018) William R. Reay et al.   MOLECULAR PSYCHIATRY

Mediterranean diet adherence is related to reduced probability of prodromal Parkinson's disease

(2018) Maria I. Maraki et al.   MOVEMENT DISORDERS

Effect of vitamin D treatment in children with attention-deficit hyperactivity disorder

(2018) Nadia Dehbokri et al.   World Journal of Pediatrics

The Role of Vitamin E in Immunity

(2018) Ga Lee et al.   Nutrients

Brain Vitamin E Deficiency During Development Is Associated With Increased Glutamate Levels and Anxiety in Adult Mice

(2018) Catherine M. Desrumaux et al.   Frontiers in Behavioral Neuroscience

Protective roles of intestinal microbiota derived short chain fatty acids in Alzheimer’s disease-type beta-amyloid neuropathological mechanisms

(2017) Lap Ho et al.   Expert Review of Neurotherapeutics

Zinc Signals and Immunity

(2017) Martina Maywald et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Association Between Dietary Factors and Mortality From Heart Disease, Stroke, and Type 2 Diabetes in the United States

(2017) Renata Micha et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Impact of combined sodium chloride and saturated long-chain fatty acid challenge on the differentiation of T helper cells in neuroinflammation

(2017) Anna Hammer et al.   Journal of Neuroinflammation

Neuronal P2X7 Receptors Revisited: Do They Really Exist?

(2017) Peter Illes et al.   JOURNAL OF NEUROSCIENCE

Probiotics modulate gut microbiota and improve insulin sensitivity in DIO mice

(2017) Renata A. Bagarolli et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Health Benefits of the Mediterranean Diet: Metabolic and Molecular Mechanisms

(2017) Valeria Tosti et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Alzheimer’s disease pathogenesis: Is there a role for folate?

(2017) Natassia Robinson et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Vitamin D signaling in intestinal innate immunity and homeostasis

(2017) Vassil Dimitrov et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Extracellular ATP and adenosine: The Yin and Yang in immune responses?

(2017) M.M. Faas et al.   MOLECULAR ASPECTS OF MEDICINE

Bifidobacterium pseudocatenulatum CECT 7765 Ameliorates Neuroendocrine Alterations Associated with an Exaggerated Stress Response and Anhedonia in Obese Mice

(2017) Ana Agusti et al.   MOLECULAR NEUROBIOLOGY

High-fat diet and aging interact to produce neuroinflammation and impair hippocampal- and amygdalar-dependent memory

(2017) Sarah J. Spencer et al.   NEUROBIOLOGY OF AGING

Gla-rich protein function as an anti-inflammatory agent in monocytes/macrophages: Implications for calcification-related chronic inflammatory diseases

(2017) Carla S. B. Viegas et al.   PLoS One

The effects of micronutrient deficiencies on bacterial species from the human gut microbiota

(2017) Matthew C. Hibberd et al.   Science Translational Medicine

Vitamin C and Infections

(2017) Harri Hemilä   Nutrients

Does Vitamin C Influence Neurodegenerative Diseases and Psychiatric Disorders?

(2017) et al.   Nutrients

Vitamin C and Immune Function

(2017) Anitra Carr et al.   Nutrients

A maternal high-fat diet during pregnancy and lactation, in addition to a postnatal high-fat diet, leads to metabolic syndrome with spatial learning and memory deficits: beneficial effects of resveratrol

(2017) Shih-Wen Li et al.   Oncotarget

Protective roles of intestinal microbiota derived short chain fatty acids in Alzheimer’s disease-type beta-amyloid neuropathological mechanisms

(2017) Lap Ho et al.   Expert Review of Neurotherapeutics

The Alpha-Tocopherol Form of Vitamin E Boosts Elastase Activity of Human PMNs and Their Ability to Kill Streptococcus pneumoniae

(2017) Elsa N. Bou Ghanem et al.   Frontiers in Cellular and Infection Microbiology

Dietary and Microbial Metabolites in the Regulation of Host Immunity

(2017) Naoko Shibata et al.   Frontiers in Microbiology

Effects of Vitamin B6 Deficiency on the Composition and Functional Potential of T Cell Populations

(2017) Bingjun Qian et al.   Journal of Immunology Research

Enterotypes in the landscape of gut microbial community composition

(2017) Paul I. Costea et al.   Nature Microbiology

Vitamin B12 Levels in Alzheimer's Disease: Association with Clinical Features and Cytokine Production

(2017) Antonis Politis et al.   JOURNAL OF ALZHEIMERS DISEASE

AhR-deficiency as a cause of demyelinating disease and inflammation

(2017) Ludmila Juricek et al.   Scientific Reports

Complete Tetrasaccharide Repeat Unit Biosynthesis of the Immunomodulatory Bacteroides fragilis Capsular Polysaccharide A

(2016) Sunita Sharma et al.   ACS Chemical Biology

Human Milk Oligosaccharides Influence Neonatal Mucosal and Systemic Immunity

(2016) Sharon M. Donovan et al.   ANNALS OF NUTRITION AND METABOLISM

Microglial response to LPS increases in wild-type mice during aging but diminishes in an Alzheimer's mouse model: Implication of TLR4 signaling in disease progression

(2016) Michelle Go et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Biosynthesis of polyamines and polyamine-containing molecules

(2016) A. J. Michael   BIOCHEMICAL JOURNAL

Modulation of the human gut microbiota by dietary fibres occurs at the species level

(2016) Wing Sun Faith Chung et al.   BMC BIOLOGY

A Central Role for ATP Signalling in Glial Interactions in the CNS

(2016) Andrea Rivera et al.   CURRENT DRUG TARGETS

Adjuvant thiamine improved standard treatment in patients with major depressive disorder: results from a randomized, double-blind, and placebo-controlled clinical trial

(2016) Ali Ghaleiha et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Effects of bile acids on neurological function and disease

(2016) Matthew McMillin et al.   FASEB JOURNAL

Normalizing Microbiota-Induced Retinoic Acid Deficiency Stimulates Protective CD8 + T Cell-Mediated Immunity in Colorectal Cancer

(2016) Nupur Bhattacharya et al.   IMMUNITY

The Aryl Hydrocarbon Receptor Modulates Production of Cytokines and Reactive Oxygen Species and Development of Myocarditis during Trypanosoma cruzi Infection

(2016) Andréia Barroso et al.   INFECTION AND IMMUNITY

An Update on Type 2 Diabetes Mellitus as a Risk Factor for Dementia

(2016) Wei Li et al.   JOURNAL OF ALZHEIMERS DISEASE

Vitamin B6 Prevents IL-1β Protein Production by Inhibiting NLRP3 Inflammasome Activation

(2016) Peipei Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Yin and Yang of copper during infection

(2016) Angelique N. Besold et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

The Molecular Mechanisms of Vitamin A Deficiency in Multiple Sclerosis

(2016) Ahmad Reza Dorosty-Motlagh et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

High folic acid intake reduces natural killer cell cytotoxicity in aged mice

(2016) Hathairat Sawaengsri et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signals

(2016) Z Chen et al.   Mucosal Immunology

Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor

(2016) Veit Rothhammer et al.   NATURE MEDICINE

ATPergic signalling during seizures and epilepsy

(2016) Tobias Engel et al.   NEUROPHARMACOLOGY

Targeting demyelination and virtual hypoxia with high-dose biotin as a treatment for progressive multiple sclerosis

(2016) Frédéric Sedel et al.   NEUROPHARMACOLOGY

Alterations of Gut Microbiota After Roux-en-Y Gastric Bypass and Sleeve Gastrectomy in Sprague-Dawley Rats

(2016) Yikai Shao et al.   OBESITY SURGERY

Obeticholic acid, a synthetic bile acid agonist of the farnesoid X receptor, attenuates experimental autoimmune encephalomyelitis

(2016) Peggy P. Ho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quercetin, Inflammation and Immunity

(2016) Yao Li et al.   Nutrients

Bidirectional communication between the Aryl hydrocarbon Receptor (AhR) and the microbiome tunes host metabolism

(2016) Agata Korecka et al.   npj Biofilms and Microbiomes

Dietary Fiber Intake Regulates Intestinal Microflora and Inhibits Ovalbumin-Induced Allergic Airway Inflammation in a Mouse Model

(2016) Zhiyu Zhang et al.   PLoS One

Western diet induces a shift in microbiota composition enhancing susceptibility to Adherent-Invasive E. coli infection and intestinal inflammation.

(2016) Allison Agus et al.   Scientific Reports

Protectins and maresins: New pro-resolving families of mediators in acute inflammation and resolution bioactive metabolome

(2015) Charles N. Serhan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Regulation of immunological and inflammatory functions by biotin

(2015) Toshinobu Kuroishi   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling

(2015) Maayan Levy et al.   CELL

The emerging role of aryl hydrocarbon receptor in the activation and differentiation of Th17 cells

(2015) Eszter Baricza et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Dietary Fatty Acids Directly Impact Central Nervous System Autoimmunity via the Small Intestine

(2015) Aiden Haghikia et al.   IMMUNITY

Suppression of the HPA Axis During Cholestasis Can Be Attributed to Hypothalamic Bile Acid Signaling

(2015) Matthew McMillin et al.   MOLECULAR ENDOCRINOLOGY

Role of intestinal microbiota in the generation of polyphenol-derived phenolic acid mediated attenuation of Alzheimer's disease β-amyloid oligomerization

(2015) Dongjie Wang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The gut microbiota modulates host amino acid and glutathione metabolism in mice

(2015) A. Mardinoglu et al.   Molecular Systems Biology

Host microbiota constantly control maturation and function of microglia in the CNS

(2015) Daniel Erny et al.   NATURE NEUROSCIENCE

Amyloid-β pathology is attenuated by tauroursodeoxycholic acid treatment in APP/PS1 mice after disease onset

(2015) Pedro A. Dionísio et al.   NEUROBIOLOGY OF AGING

UDCA exerts beneficial effect on mitochondrial dysfunction inLRRK2G2019Scarriers and in vivo

(2015) Heather Mortiboys et al.   NEUROLOGY

How the Mediterranean diet and some of its components modulate inflammatory pathways in arthritis

(2015) F Oliviero et al.   SWISS MEDICAL WEEKLY

Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome

(2015) Laurence Macia et al.   Nature Communications

Enhanced Human Neutrophil Vitamin C Status, Chemotaxis and Oxidant Generation Following Dietary Supplementation with Vitamin C-Rich SunGold Kiwifruit

(2015) Stephanie Bozonet et al.   Nutrients

Mode of Bioenergetic Metabolism during B Cell Differentiation in the Intestine Determines the Distinct Requirement for Vitamin B 1

(2015) Jun Kunisawa et al.   Cell Reports

Deletion of mouse FXR gene disturbs multiple neurotransmitter systems and alters neurobehavior

(2015) Fei Huang et al.   Frontiers in Behavioral Neuroscience

Benfotiamine Attenuates Inflammatory Response in LPS Stimulated BV-2 Microglia

(2015) Iva Bozic et al.   PLoS One

High Percentage of Regulatory T Cells before and after Vitamin B12 Treatment in Patients with Pernicious Anemia

(2014) Satoru Watanabe et al.   ACTA HAEMATOLOGICA

Caecal environment of rats fed far East Asian-modelled diets

(2014) Choa An et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Thiamin Function, Metabolism, Uptake, and Transport

(2014) Sergio Manzetti et al.   BIOCHEMISTRY

Role of free fatty acid receptors in the regulation of energy metabolism

(2014) Takafumi Hara et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Diet-induced obesity progressively alters cognition, anxiety-like behavior and lipopolysaccharide-induced depressive-like behavior: Focus on brain indoleamine 2,3-dioxygenase activation

(2014) Caroline André et al.   BRAIN BEHAVIOR AND IMMUNITY

Bile acids permeabilize the blood brain barrier after bile duct ligation in rats via Rac1-dependent mechanisms

(2014) Matthew Quinn et al.   DIGESTIVE AND LIVER DISEASE

P2X7-dependent, but differentially regulated release of IL-6, CCL2, and TNF-α in cultured mouse microglia

(2014) Chu-Hsin Shieh et al.   GLIA

ATP-Gated Ionotropic P2X7 Receptor Controls Follicular T Helper Cell Numbers in Peyer’s Patches to Promote Host-Microbiota Mutualism

(2014) Michele Proietti et al.   IMMUNITY

Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis

(2014) Nagendra Singh et al.   IMMUNITY

Identification of a probiotic bacteria-derived activator of the aryl hydrocarbon receptor that inhibits colitis

(2014) Suguru Fukumoto et al.   IMMUNOLOGY AND CELL BIOLOGY

Comparative effect of fucoxanthin and vitamin C on oxidative and functional parameters of human lymphocytes

(2014) Nathalia Molina et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The short chain fatty acid propionate stimulates GLP-1 and PYY secretion via free fatty acid receptor 2 in rodents

(2014) A Psichas et al.   INTERNATIONAL JOURNAL OF OBESITY

A Gut Microbial Metabolite of Linoleic Acid, 10-Hydroxy-cis-12-octadecenoic Acid, Ameliorates Intestinal Epithelial Barrier Impairment Partially via GPR40-MEK-ERK Pathway

(2014) Junki Miyamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thiamine Deficiency Promotes T Cell Infiltration in Experimental Autoimmune Encephalomyelitis: The Involvement of CCL2

(2014) Zhe Ji et al.   JOURNAL OF IMMUNOLOGY

Green Tea, Black Tea, and Oolong Tea Polyphenols Reduce Visceral Fat and Inflammation in Mice Fed High-Fat, High-Sucrose Obesogenic Diets

(2014) David Heber et al.   JOURNAL OF NUTRITION

Aryl hydrocarbon receptor control of a disease tolerance defence pathway

(2014) Alban Bessede et al.   NATURE

Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis

(2014) Aurélien Trompette et al.   NATURE MEDICINE

Fast food fever: reviewing the impacts of the Western diet on immunity

(2014) Ian A Myles   Nutrition Journal

Effects of Bile Acids and the Bile Acid Receptor FXR Agonist on the Respiratory Rhythm in the In Vitro Brainstem Medulla Slice of Neonatal Sprague-Dawley Rats

(2014) Cong Zhao et al.   PLoS One

Control of appetite and energy intake by SCFA: what are the potential underlying mechanisms?

(2014) Edward S. Chambers et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Increasing Iron and Zinc in Pre-Menopausal Women and Its Effects on Mood and Cognition: A Systematic Review

(2014) Karla Lomagno et al.   Nutrients

Toward Understanding the Role of Aryl Hydrocarbon Receptor in the Immune System: Current Progress and Future Trends

(2014) Hamza Hanieh   Biomed Research International

Extracellular Adenosine-Mediated Modulation of Regulatory T Cells

(2014) Akio Ohta et al.   Frontiers in Immunology

Dietary Fiber Intake and Cardiometabolic Risks among US Adults, NHANES 1999-2010

(2013) Kya N. Grooms et al.   AMERICAN JOURNAL OF MEDICINE

Mediterranean diet, stroke, cognitive impairment, and depression: A meta-analysis

(2013) Theodora Psaltopoulou et al.   ANNALS OF NEUROLOGY

Long-Chain Acyl Coenzyme A Synthetase 1 Overexpression in Primary Cultured Schwann Cells Prevents Long Chain Fatty Acid-Induced Oxidative Stress and Mitochondrial Dysfunction

(2013) Lucy M. Hinder et al.   ANTIOXIDANTS & REDOX SIGNALING

Glucose Triggers ATP Secretion from Bacteria in a Growth-Phase-Dependent Manner

(2013) Ippei Hironaka et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Bile Acid Receptor TGR5 Agonism Induces NO Production and Reduces Monocyte Adhesion in Vascular Endothelial Cells

(2013) Taiki Kida et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Riboflavin deprivation inhibits macrophage viability and activity – a study on the RAW 264.7 cell line

(2013) Agnieszka Irena Mazur-Bialy et al.   BRITISH JOURNAL OF NUTRITION

Iron in Infection and Immunity

(2013) James E. Cassat et al.   Cell Host & Microbe

Clinical recognition and aspects of the cerebral folate deficiency syndromes

(2013) Vincent Ramaekers et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Riboflavin (vitamin B2) deficiency impairs NADPH oxidase 2 (Nox2) priming and defense againstListeria monocytogenes

(2013) Michael Schramm et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Serum levels of vitamin E forms and risk of cognitive impairment in a Finnish cohort of older adults

(2013) Francesca Mangialasche et al.   EXPERIMENTAL GERONTOLOGY

G Protein-Coupled Receptor 43 Moderates Gut Inflammation Through Cytokine Regulation from Mononuclear Cells

(2013) Ryuta Masui et al.   INFLAMMATORY BOWEL DISEASES

Aryl hydrocarbon receptor protects against bacterial infection by promoting macrophage survival and reactive oxygen species production

(2013) Akihiro Kimura et al.   INTERNATIONAL IMMUNOLOGY

High-fat diet alters gut microbiota physiology in mice

(2013) Hannelore Daniel et al.   ISME Journal

Extracellular adenosine regulates naive T cell development and peripheral maintenance

(2013) Caglar Cekic et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism

(2013) Gijs den Besten et al.   JOURNAL OF LIPID RESEARCH

Vitamin D Regulates the Gut Microbiome and Protects Mice from Dextran Sodium Sulfate–Induced Colitis

(2013) Jot Hui Ooi et al.   JOURNAL OF NUTRITION

Short-Chain Fatty Acids Stimulate Angiopoietin-Like 4 Synthesis in Human Colon Adenocarcinoma Cells by Activating Peroxisome Proliferator-Activated Receptor  

(2013) S. Alex et al.   MOLECULAR AND CELLULAR BIOLOGY

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

(2013) Nicholas Arpaia et al.   NATURE

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

Vitamin E is essential for Purkinje neuron integrity

(2013) L. Ulatowski et al.   NEUROSCIENCE

Intranasal LPS-Mediated Parkinson’s Model Challenges the Pathogenesis of Nasal Cavity and Environmental Toxins

(2013) Qing He et al.   PLoS One

Butyrate increases IL-23 production by stimulated dendritic cells

(2012) Bradford E. Berndt et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Butyrate interferes with the differentiation and function of human monocyte-derived dendritic cells

(2012) Lu Liu et al.   CELLULAR IMMUNOLOGY

Metabolic Dysfunction in Alzheimers Disease and Related Neurodegenerative Disorders

(2012) Huan Cai et al.   Current Alzheimer Research

Resveratrol Attenuates Obesity-Associated Peripheral and Central Inflammation and Improves Memory Deficit in Mice Fed a High-Fat Diet

(2012) B. T. Jeon et al.   DIABETES

Gut-derived lipopolysaccharide augments adipose macrophage accumulation but is not essential for impaired glucose or insulin tolerance in mice

(2012) Robert Caesar et al.   GUT

Adenosine and cAMP signalling skew human dendritic cell differentiation towards a tolerogenic phenotype with defective CD8+T-cell priming capacity

(2012) John Challier et al.   IMMUNOLOGY

Inhibition of P2X7 receptor ameliorates transient global cerebral ischemia/reperfusion injury via modulating inflammatory responses in the rat hippocampus

(2012) Ketan Chu et al.   Journal of Neuroinflammation

Receptor-specific regulation of ERK1/2 activation by members of the “free fatty acid receptor” family

(2012) Sandra Seljeset et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Functional interactions between the gut microbiota and host metabolism

(2012) Valentina Tremaroli et al.   NATURE

Structure, function and diversity of the healthy human microbiome

(2012)   NATURE

Microbes and the gut-brain axis

(2012) P. Bercik et al.   NEUROGASTROENTEROLOGY AND MOTILITY

An inhibitory effect of resveratrol in the mitotic clonal expansion and insulin signaling pathway in the early phase of adipogenesis

(2012) Jung Yeon Kwon et al.   NUTRITION RESEARCH

Green Tea Polyphenols Reduce Body Weight in Rats by Modulating Obesity-Related Genes

(2012) Chuanwen Lu et al.   PLoS One

Exogenous Stimuli Maintain Intraepithelial Lymphocytes via Aryl Hydrocarbon Receptor Activation

(2011) Ying Li et al.   CELL

TGR5 Activation Inhibits Atherosclerosis by Reducing Macrophage Inflammation and Lipid Loading

(2011) Thijs W.H. Pols et al.   Cell Metabolism

Short-Chain Fatty Acids Stimulate Glucagon-Like Peptide-1 Secretion via the G-Protein-Coupled Receptor FFAR2

(2011) G. Tolhurst et al.   DIABETES

The G-Protein-coupled bile acid receptor, Gpbar1 (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor kappa light-chain enhancer of activated B cells (NF-κB) in mice

(2011) Yan-Dong Wang et al.   HEPATOLOGY

The Aryl Hydrocarbon Receptor Regulates Gut Immunity through Modulation of Innate Lymphoid Cells

(2011) Ju Qiu et al.   IMMUNITY

TLR4 mutation reduces microglial activation, increases Aβ deposits and exacerbates cognitive deficits in a mouse model of Alzheimer's disease

(2011) Min Song et al.   Journal of Neuroinflammation

Resveratrol regulates lipolysis via adipose triglyceride lipase

(2011) Arrate Lasa et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

(−)-Epigallocatechin-3-gallate blocks 3T3-L1 adipose conversion by inhibition of cell proliferation and suppression of adipose phenotype expression

(2011) Cheuk Ying Chan et al.   LIFE SCIENCES

Enterotypes of the human gut microbiome

(2011) Manimozhiyan Arumugam et al.   NATURE

d-Arginine action against neurotoxicity induced by glucocorticoids in the brain

(2011) Canteros Maria Griselda   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The bile steroid chenodeoxycholate is a potent antagonist at NMDA and GABAA receptors

(2011) S.R. Schubring et al.   NEUROSCIENCE LETTERS

SCFAs Induce Mouse Neutrophil Chemotaxis through the GPR43 Receptor

(2011) Marco A. R. Vinolo et al.   PLoS One

The Bile Acid Receptor GPBAR-1 (TGR5) Modulates Integrity of Intestinal Barrier and Immune Response to Experimental Colitis

(2011) Sabrina Cipriani et al.   PLoS One

Linking Long-Term Dietary Patterns with Gut Microbial Enterotypes

(2011) G. D. Wu et al.   SCIENCE

Intestinal health functions of colonic microbial metabolites: a review

(2011) R. Havenaar   Beneficial Microbes

Resveratrol modulates adipokine expression and improves insulin sensitivity in adipocytes: Relative to inhibition of inflammatory responses

(2010) Liu Kang et al.   BIOCHIMIE

Butyrate in vitro immune-modulatory effects might be mediated through a proliferation-related induction of apoptosis

(2010) Elvira Bailón et al.   IMMUNOBIOLOGY

G-protein-coupled receptor for short-chain fatty acids suppresses colon cancer

(2010) Yong Tang et al.   INTERNATIONAL JOURNAL OF CANCER

Central Nervous System Demyelinating Disease Protection by the Human Commensal Bacteroides fragilis Depends on Polysaccharide A Expression

(2010) J. Ochoa-Reparaz et al.   JOURNAL OF IMMUNOLOGY

Efficient Induction of CCR9 on T Cells Requires Coactivation of Retinoic Acid Receptors and Retinoid X Receptors (RXRs): Exaggerated T Cell Homing to the Intestine by RXR Activation with Organotins

(2010) H. Takeuchi et al.   JOURNAL OF IMMUNOLOGY

Development of a grape seed polyphenolic extract with anti-oligomeric activity as a novel treatment in progressive supranuclear palsy and other tauopathies

(2010) Giulio Maria Pasinetti et al.   JOURNAL OF NEUROCHEMISTRY

Curcumin inhibits adipocyte differentiation through modulation of mitotic clonal expansion

(2010) Choon Young Kim et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Suppressive effect of short-chain fatty acids on production of proinflammatory mediators by neutrophils

(2010) Marco A.R. Vinolo et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

Vitamin D controls T cell antigen receptor signaling and activation of human T cells

(2010) Marina Rode von Essen et al.   NATURE IMMUNOLOGY

Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa

(2010) C. De Filippo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The new ‘5-HT’ hypothesis of depression: Cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression

(2010) M. Maes et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Therapeutic potential of n-3 polyunsaturated fatty acids in disease

(2009) J. W. Fetterman et al.   AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY

Curcumin, a Potential Inhibitor of Up-regulation of TNF-alpha and IL-6 Induced by Palmitate in 3T3-L1 Adipocytes through NF-kappaB and JNK Pathway

(2009) Shao-Ling WANG et al.   BIOMEDICAL AND ENVIRONMENTAL SCIENCES

Hematopoietic Cell-Specific Deletion of Toll-like Receptor 4 Ameliorates Hepatic and Adipose Tissue Insulin Resistance in High-Fat-Fed Mice

(2009) Maziyar Saberi et al.   Cell Metabolism

Short chain fatty acids exchange across the gut and liver in humans measured at surgery

(2009) Johanne G. Bloemen et al.   CLINICAL NUTRITION

Influence of breast milk polyamines on suckling rat immune system maturation

(2009) Francisco J. Pérez-Cano et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

High-Fat Diet Determines the Composition of the Murine Gut Microbiome Independently of Obesity

(2009) Marie A. Hildebrandt et al.   GASTROENTEROLOGY

Adenosine regulates CD8 T-cell priming by inhibition of membrane-proximal T-cell receptor signalling

(2009) Carsten Linnemann et al.   IMMUNOLOGY

The Bile Acid Receptor FXR Is a Modulator of Intestinal Innate Immunity

(2009) P. Vavassori et al.   JOURNAL OF IMMUNOLOGY

The A2B Adenosine Receptor Impairs the Maturation and Immunogenicity of Dendritic Cells

(2009) J. M. Wilson et al.   JOURNAL OF IMMUNOLOGY

Western-Style Diets Induce Oxidative Stress and Dysregulate Immune Responses in the Colon in a Mouse Model of Sporadic Colon Cancer

(2009) Ildiko Erdelyi et al.   JOURNAL OF NUTRITION

Activation of the AMP activated protein kinase by short-chain fatty acids is the main mechanism underlying the beneficial effect of a high fiber diet on the metabolic syndrome

(2009) Guo-Xin Hu et al.   MEDICAL HYPOTHESES

Hypersensitivity of Aryl Hydrocarbon Receptor-Deficient Mice to Lipopolysaccharide-Induced Septic Shock

(2009) H. Sekine et al.   MOLECULAR AND CELLULAR BIOLOGY

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(2009) Shu Zhu et al.   MOLECULAR MEDICINE

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

(2009) Kendle M. Maslowski et al.   NATURE

The multi-faceted basis of vitamin B12 (cobalamin) neurotrophism in adult central nervous system: Lessons learned from its deficiency

(2009) G. Scalabrino   PROGRESS IN NEUROBIOLOGY

Short-chain fatty acids act as antiinflammatory mediatorsby regulating prostaglandin E2 and cytokines

(2009) Mary Ann Cox et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Arginase-1–Expressing Macrophages Suppress Th2 Cytokine–Driven Inflammation and Fibrosis

(2009) John T. Pesce et al.   PLoS Pathogens

Inhibition of circulating immune cell activation: a molecular antiinflammatory effect of the Mediterranean diet

(2008) Mari-Pau Mena et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Dietary resistant starch upregulates total GLP-1 and PYY in a sustained day-long manner through fermentation in rodents

(2008) June Zhou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Anti-inflammatory effect of resveratrol on TNF-α-induced MCP-1 expression in adipocytes

(2008) Jian Zhu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Adenosine receptors in regulation of dendritic cell differentiation and function

(2008) S. V. Novitskiy et al.   BLOOD

Grape-Derived Polyphenolics Prevent A  Oligomerization and Attenuate Cognitive Deterioration in a Mouse Model of Alzheimer's Disease

(2008) J. Wang et al.   JOURNAL OF NEUROSCIENCE

A microbial symbiosis factor prevents intestinal inflammatory disease

(2008) Sarkis K. Mazmanian et al.   NATURE

ATP drives lamina propria TH17 cell differentiation

(2008) Koji Atarashi et al.   NATURE

Quercetin Ameliorates Metabolic Syndrome and Improves the Inflammatory Status in Obese Zucker Rats

(2008) Leonor Rivera et al.   Obesity