The G-Protein-coupled bile acid receptor, Gpbar1 (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor kappa light-chain enhancer of activated B cells (NF-κB) in mice

NF-κB and STAT3 – key players in liver inflammation and cancer

(2010) Guobin He et al.   CELL RESEARCH

Shilianhua extract inhibits GSK-3β and promotes glucose metabolism

(2009) Jun Yin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity

(2009) Takeshi Yoshizaki et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology

TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis

(2009) Charles Thomas et al.   Cell Metabolism

Inflammation and endoplasmic reticulum stress in obesity and diabetes

(2009) G S Hotamisligil   INTERNATIONAL JOURNAL OF OBESITY

Lipopolysaccharide triggered TNF-α-induced hepatocyte apoptosis in a murine non-alcoholic steatohepatitis model

(2009) Hiroshi Kudo et al.   JOURNAL OF HEPATOLOGY

Bile-acid-activated receptors: targeting TGR5 and farnesoid-X-receptor in lipid and glucose disorders

(2009) Stefano Fiorucci et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Expression and function of the bile acid receptor TGR5 in Kupffer cells

(2008) Verena Keitel et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

NF-κB and cancer—identifying targets and mechanisms

(2008) Willscott E Naugler et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Farnesoid X receptor antagonizes nuclear factor κB in hepatic inflammatory response

(2008) Yan-Dong Wang et al.   HEPATOLOGY

G Protein–Coupled Receptor Connectivity to NF-κB in Inflammation and Cancer

(2008) Christopher C. Fraser   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Constitutive activation of G protein-coupled receptors and diseases: Insights into mechanisms of activation and therapeutics

(2008) Y TAO   PHARMACOLOGY & THERAPEUTICS

Bile Acids and the Membrane Bile Acid Receptor TGR5—Connecting Nutrition and Metabolism

(2008) Charles Thomas et al.   THYROID

NF-kappaB: a potential target for cancer chemoprevention and therapy

(2007) Fazlul et al.   Frontiers in Bioscience-Landmark