Obeticholic acid, a synthetic bile acid agonist of the farnesoid X receptor, attenuates experimental autoimmune encephalomyelitis
出版年份 2016 全文链接
标题
Obeticholic acid, a synthetic bile acid agonist of the farnesoid X receptor, attenuates experimental autoimmune encephalomyelitis
作者
关键词
-
出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 113, Issue 6, Pages 1600-1605
出版商
Proceedings of the National Academy of Sciences
发表日期
2016-01-26
DOI
10.1073/pnas.1524890113
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial
- (2015) Brent A Neuschwander-Tetri et al. LANCET
- Obeticholic acid for the treatment of primary biliary cirrhosis
- (2015) Palak J Trivedi et al. Expert Review of Clinical Pharmacology
- Beyond CTLA-4 and PD-1, the Generation Z of Negative Checkpoint Regulators
- (2015) Isabelle Le Mercier et al. Frontiers in Immunology
- Natalizumab: A Review of Its Use in the Management of Relapsing-Remitting Multiple Sclerosis
- (2013) Paul L. McCormack DRUGS
- Efficacy and Safety of the Farnesoid X Receptor Agonist Obeticholic Acid in Patients With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease
- (2013) Sunder Mudaliar et al. GASTROENTEROLOGY
- A Role of the Bile Salt Receptor FXR in Atherosclerosis
- (2010) Jurre Hageman et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Bile acids and their nuclear receptor FXR: Relevance for hepatobiliary and gastrointestinal disease
- (2010) Raffaella M. Gadaleta et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- The PD-1 pathway in tolerance and autoimmunity
- (2010) Loise M. Francisco et al. IMMUNOLOGICAL REVIEWS
- Immune regulatory CNS-reactive CD8+T cells in experimental autoimmune encephalomyelitis
- (2010) Nathan R. York et al. JOURNAL OF AUTOIMMUNITY
- Peroxisome proliferator–activated receptor δ limits the expansion of pathogenic Th cells during central nervous system autoimmunity
- (2010) Shannon E. Dunn et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Functional Characterization of the Semisynthetic Bile Acid Derivative INT-767, a Dual Farnesoid X Receptor and TGR5 Agonist
- (2010) G. Rizzo et al. MOLECULAR PHARMACOLOGY
- Inflammation Impairs Reverse Cholesterol Transport In Vivo
- (2009) Fiona C. McGillicuddy et al. CIRCULATION
- Yin-Yang of costimulation: crucial controls of immune tolerance and function
- (2009) Roza I. Nurieva et al. IMMUNOLOGICAL REVIEWS
- PD-1 signaling in primary T cells
- (2009) James L. Riley IMMUNOLOGICAL REVIEWS
- The nuclear receptor PPARγ selectively inhibits Th17 differentiation in a T cell–intrinsic fashion and suppresses CNS autoimmunity
- (2009) Luisa Klotz et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The Bile Acid Sensor Farnesoid X Receptor Is a Modulator of Liver Immunity in a Rodent Model of Acute Hepatitis
- (2009) A. Mencarelli et al. JOURNAL OF IMMUNOLOGY
- The Bile Acid Receptor FXR Is a Modulator of Intestinal Innate Immunity
- (2009) P. Vavassori et al. JOURNAL OF IMMUNOLOGY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started