Lipid transporter Spns2 promotes microglia pro-inflammatory activation in response to amyloid-beta peptide
出版年份 2018 全文链接
标题
Lipid transporter Spns2 promotes microglia pro-inflammatory activation in response to amyloid-beta peptide
作者
关键词
-
出版物
GLIA
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2018-11-29
DOI
10.1002/glia.23558
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- MFSD2B is a sphingosine 1-phosphate transporter in erythroid cells
- (2018) Naoki Kobayashi et al. Scientific Reports
- Platycodin D Inhibits Inflammatory Response in LPS-Stimulated Primary Rat Microglia Cells through Activating LXRα–ABCA1 Signaling Pathway
- (2018) Yunhe Fu et al. Frontiers in Immunology
- Microglia and C9orf72 in neuroinflammation and ALS and frontotemporal dementia
- (2017) Deepti Lall et al. JOURNAL OF CLINICAL INVESTIGATION
- Genome-wide in vivo screen identifies novel host regulators of metastatic colonization
- (2017) Louise van der Weyden et al. NATURE
- Lymphatic endothelial S1P promotes mitochondrial function and survival in naive T cells
- (2017) Alejandra Mendoza et al. NATURE
- Mfsd2b is essential for the sphingosine-1-phosphate export in erythrocytes and platelets
- (2017) Thiet M. Vu et al. NATURE
- Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
- (2017) Rebecca Sims et al. NATURE GENETICS
- Production of proinflammatory mediators in activated microglia is synergistically regulated by Notch-1, glycogen synthase kinase (GSK-3β) and NF-κB/p65 signalling
- (2017) Qiong Cao et al. PLoS One
- Sphingosine 1-phosphate receptor modulation suppresses pathogenic astrocyte activation and chronic progressive CNS inflammation
- (2017) Veit Rothhammer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An environment-dependent transcriptional network specifies human microglia identity
- (2017) David Gosselin et al. SCIENCE
- Microglia Responses in Acute and Chronic Neurological Diseases: What Microglia-Specific Transcriptomic Studies Taught (and did Not Teach) Us
- (2017) Hélène E. Hirbec et al. Frontiers in Aging Neuroscience
- Cognitive and behavioral evaluation of nutritional interventions in rodent models of brain aging and dementia
- (2017) Devin Wahl et al. Clinical Interventions in Aging
- Toll-Like Receptor 4 Is Essential for the Expression of Sphingosine-1-Phosphate-Dependent Asthma-Like Disease in Mice
- (2017) Fiorentina Roviezzo et al. Frontiers in Immunology
- Conditional rod photoreceptor ablation revealsSall1as a microglial marker and regulator of microglial morphology in the retina
- (2016) Hideto Koso et al. GLIA
- Targeting microglia for the treatment of Alzheimer's Disease
- (2016) Paul D. Wes et al. GLIA
- Sphingosine kinase 1/sphingosine-1-phosphate regulates the expression of interleukin-17A in activated microglia in cerebral ischemia/reperfusion
- (2016) Manhua Lv et al. INFLAMMATION RESEARCH
- Microglial immunophenotype in dementia with Alzheimer’s pathology
- (2016) Thais Minett et al. Journal of Neuroinflammation
- M1 and M2 Functional Imprinting of Primary Microglia: Role of P2X7 Activation and miR-125b
- (2016) Chiara Parisi et al. MEDIATORS OF INFLAMMATION
- Fingolimod modulates multiple neuroinflammatory markers in a mouse model of Alzheimer’s disease
- (2016) Nurgul Aytan et al. Scientific Reports
- TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
- (2015) Yaming Wang et al. CELL
- Spinster 2, a sphingosine-1-phosphate transporter, plays a critical role in inflammatory and autoimmune diseases
- (2015) Michael S. Donoviel et al. FASEB JOURNAL
- Transient activation of microglia following acute alcohol exposure in developing mouse neocortex is primarily driven by BAX-dependent neurodegeneration
- (2015) Katelin E. Ahlers et al. GLIA
- MSX3 Switches Microglia Polarization and Protects from Inflammation-Induced Demyelination
- (2015) Z. Yu et al. JOURNAL OF NEUROSCIENCE
- Exogenous S1P Exposure Potentiates Ischemic Stroke Damage That Is Reduced Possibly by Inhibiting S1P Receptor Signaling
- (2015) Eunjung Moon et al. MEDIATORS OF INFLAMMATION
- TREM2 in CNS homeostasis and neurodegenerative disease
- (2015) Meghan M. Painter et al. Molecular Neurodegeneration
- Depletion of microglia and inhibition of exosome synthesis halt tau propagation
- (2015) Hirohide Asai et al. NATURE NEUROSCIENCE
- Targeting microglia for the treatment of Alzheimer’s disease
- (2014) Patrick L McGeer et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Export of sphingosine-1-phosphate and cancer progression
- (2014) Kazuaki Takabe et al. JOURNAL OF LIPID RESEARCH
- An update on the biology of sphingosine 1-phosphate receptors
- (2014) Victoria A. Blaho et al. JOURNAL OF LIPID RESEARCH
- Microglia receptors and their implications in the response to amyloid β for Alzheimer’s disease pathogenesis
- (2014) Deborah Doens et al. Journal of Neuroinflammation
- Neuroinflammation and M2 microglia: the good, the bad, and the inflamed
- (2014) Jonathan D Cherry et al. Journal of Neuroinflammation
- Sphingolipid metabolites in inflammatory disease
- (2014) Michael Maceyka et al. NATURE
- Evidence of Trem2 Variant Associated with Triple Risk of Alzheimer’s Disease
- (2014) Zainularifeen Abduljaleel et al. PLoS One
- Critical Role of Spns2, a Sphingosine-1-Phosphate Transporter, in Lung Cancer Cell Survival and Migration
- (2014) Eric Bradley et al. PLoS One
- Synergy between Sphingosine 1-Phosphate and Lipopolysaccharide Signaling Promotes an Inflammatory, Angiogenic and Osteogenic Response in Human Aortic Valve Interstitial Cells
- (2014) Isabel Fernández-Pisonero et al. PLoS One
- Preconditioning provides neuroprotection in models of CNS disease: Paradigms and clinical significance
- (2014) R. Anne Stetler et al. PROGRESS IN NEUROBIOLOGY
- Spinster Homolog 2 (Spns2) Deficiency Causes Early Onset Progressive Hearing Loss
- (2014) Jing Chen et al. PLoS Genetics
- Loss of the neuroprotective factor Sphingosine 1-phosphate early in Alzheimer’s disease pathogenesis
- (2014) Timothy A Couttas et al. Acta Neuropathologica Communications
- Reduced sphingosine kinase-1 and enhanced sphingosine 1-phosphate lyase expression demonstrate deregulated sphingosine 1-phosphate signaling in Alzheimer’s disease
- (2014) Johnatan Ceccom et al. Acta Neuropathologica Communications
- A new metabolomic workflow for early detection of Alzheimer's disease
- (2013) Clara Ibáñez et al. JOURNAL OF CHROMATOGRAPHY A
- Fingolimod phosphate promotes the neuroprotective effects of microglia
- (2013) Hiromi Noda et al. JOURNAL OF NEUROIMMUNOLOGY
- Cytokines and Chemokines at the Crossroads of Neuroinflammation, Neurodegeneration, and Neuropathic Pain
- (2013) Geeta Ramesh et al. MEDIATORS OF INFLAMMATION
- Identification of a unique TGF-β–dependent molecular and functional signature in microglia
- (2013) Oleg Butovsky et al. NATURE NEUROSCIENCE
- FTY720/Fingolimod, a Sphingosine Analogue, Reduces Amyloid-β Production in Neurons
- (2013) Nobumasa Takasugi et al. PLoS One
- Sphingosine-1-Phosphate Links Persistent STAT3 Activation, Chronic Intestinal Inflammation, and Development of Colitis-Associated Cancer
- (2012) Jie Liang et al. CANCER CELL
- Spns2, a transporter of phosphorylated sphingoid bases, regulates their blood and lymph levels, and the lymphatic network
- (2012) Masayuki Nagahashi et al. FASEB JOURNAL
- Regulation of microglia activation and deactivation by nuclear receptors
- (2012) Kaoru Saijo et al. GLIA
- Regulation of microglia development and homeostasis
- (2012) Melanie Greter et al. GLIA
- Microglia and neurodegeneration: The role of systemic inflammation
- (2012) Colm Cunningham GLIA
- The functional roles of S1P in immunity
- (2012) Y. Hisano et al. JOURNAL OF BIOCHEMISTRY
- The Role of Sphingosine-1-Phosphate Transporter Spns2 in Immune System Function
- (2012) A. Nijnik et al. JOURNAL OF IMMUNOLOGY
- Lipopolysaccharide-Induced Microglial Activation and Neuroprotection against Experimental Brain Injury Is Independent of Hematogenous TLR4
- (2012) Z. Chen et al. JOURNAL OF NEUROSCIENCE
- Mechanisms Underlying the Rapid Peroxisome Proliferator-Activated Receptor- -Mediated Amyloid Clearance and Reversal of Cognitive Deficits in a Murine Model of Alzheimer's Disease
- (2012) S. Mandrekar-Colucci et al. JOURNAL OF NEUROSCIENCE
- Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer
- (2012) Zhenfeng Zhang et al. NATURE GENETICS
- Variant of TREM2 Associated with the Risk of Alzheimer's Disease
- (2012) Thorlakur Jonsson et al. NEW ENGLAND JOURNAL OF MEDICINE
- ApoE-Directed Therapeutics Rapidly Clear -Amyloid and Reverse Deficits in AD Mouse Models
- (2012) P. E. Cramer et al. SCIENCE
- The Transporter Spns2 Is Required for Secretion of Lymph but Not Plasma Sphingosine-1-Phosphate
- (2012) Alejandra Mendoza et al. Cell Reports
- Sphingosine-1-phosphate links glycosphingolipid metabolism to neurodegeneration via a calpain-mediated mechanism
- (2011) N Hagen et al. CELL DEATH AND DIFFERENTIATION
- BACE1 Activity Is Modulated by Cell-Associated Sphingosine-1-Phosphate
- (2011) N. Takasugi et al. JOURNAL OF NEUROSCIENCE
- Oral fingolimod (FTY720) in relapsing multiple sclerosis: impact on health-related quality of life in a phase II study
- (2011) X Montalban et al. Multiple Sclerosis Journal
- Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
- (2011) Adam C Naj et al. NATURE GENETICS
- Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
- (2011) Paul Hollingworth et al. NATURE GENETICS
- Sphingosine-1-phosphate signaling and its role in disease
- (2011) Michael Maceyka et al. TRENDS IN CELL BIOLOGY
- CNS expression of anti-inflammatory cytokine interleukin-4 attenuates Alzheimer’s disease-like pathogenesis in APP+PS1 bigenic mice
- (2010) Tomomi Kiyota et al. FASEB JOURNAL
- Cathepsin S release from primary cultured microglia is regulated by the P2X7 receptor
- (2010) Anna K. Clark et al. GLIA
- Microglial activation depends on beta-amyloid conformation: role of the formylpeptide receptor 2
- (2010) Tony Heurtaux et al. JOURNAL OF NEUROCHEMISTRY
- Tyk2/STAT3 Signaling Mediates -Amyloid-Induced Neuronal Cell Death: Implications in Alzheimer's Disease
- (2010) J. Wan et al. JOURNAL OF NEUROSCIENCE
- Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2
- (2010) Sergio E. Alvarez et al. NATURE
- Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis
- (2010) Volker Brinkmann et al. NATURE REVIEWS DRUG DISCOVERY
- Distinct mechanisms for the impact of distraction and interruption on working memory in aging
- (2010) Wesley C. Clapp et al. NEUROBIOLOGY OF AGING
- Anti-inflammatory drugs and risk of Parkinson disease: A meta-analysis
- (2010) J. J. Gagne et al. NEUROLOGY
- Export and functions of sphingosine-1-phosphate
- (2009) Roger H. Kim et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Sphingosine-1-Phosphate Induces an Antiinflammatory Phenotype in Macrophages
- (2008) Jeniter E. Hughes et al. CIRCULATION RESEARCH
- The Spinster Homolog, Two of Hearts, Is Required for Sphingosine 1-Phosphate Signaling in Zebrafish
- (2008) Nick Osborne et al. CURRENT BIOLOGY
- TLR4 and S1P receptors cooperate to enhance inflammatory cytokine production in human gingival epithelial cells
- (2008) Mehmet A. Eskan et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- TREM2 is upregulated in amyloid plaque-associated microglia in aged APP23 transgenic mice
- (2008) Stefanie Frank et al. GLIA
- Neuro-inflammation induced by lipopolysaccharide causes cognitive impairment through enhancement of beta-amyloid generation
- (2008) Jae Lee et al. Journal of Neuroinflammation
- Deregulation of sphingolipid metabolism in Alzheimer's disease
- (2008) Xingxuan He et al. NEUROBIOLOGY OF AGING
- Protective effects of NSAIDs on the development of Alzheimer disease
- (2008) Steven C. Vlad et al. NEUROLOGY
- The Sphingolipid Transporter Spns2 Functions in Migration of Zebrafish Myocardial Precursors
- (2008) A. Kawahara et al. SCIENCE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started