标题
FTY720/Fingolimod, a Sphingosine Analogue, Reduces Amyloid-β Production in Neurons
作者
关键词
-
出版物
PLoS One
Volume 8, Issue 5, Pages e64050
出版商
Public Library of Science (PLoS)
发表日期
2013-05-08
DOI
10.1371/journal.pone.0064050
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Effects of Membrane Lipids on the Activity and Processivity of Purified γ-Secretase
- (2012) Oliver Holmes et al. BIOCHEMISTRY
- The β-Arrestin-Like Protein Rim8 Is Hyperphosphorylated and Complexes with Rim21 and Rim101 To Promote Adaptation to Neutral-Alkaline pH
- (2012) Jonathan Gomez-Raja et al. EUKARYOTIC CELL
- Internal Amino Acids Promote Gap1 Permease Ubiquitylation via TORC1/Npr1/14-3-3-Dependent Control of the Bul Arrestin-Like Adaptors
- (2012) A. Merhi et al. MOLECULAR AND CELLULAR BIOLOGY
- β-arrestin 2 regulates Aβ generation and γ-secretase activity in Alzheimer's disease
- (2012) Amantha Thathiah et al. NATURE MEDICINE
- Activity-Dependent Proteolytic Cleavage of Neuroligin-1
- (2012) Kunimichi Suzuki et al. NEURON
- BACE1 Activity Is Modulated by Cell-Associated Sphingosine-1-Phosphate
- (2011) N. Takasugi et al. JOURNAL OF NEUROSCIENCE
- The role of APP proteolytic processing in lipid metabolism
- (2011) Marcus O. W. Grimm et al. EXPERIMENTAL BRAIN RESEARCH
- Roles for dysfunctional sphingolipid metabolism in Alzheimer's disease neuropathogenesis
- (2010) Norman J. Haughey et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Membrane rafts in Alzheimer's disease beta-amyloid production
- (2010) Kulandaivelu S. Vetrivel et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis
- (2010) Volker Brinkmann et al. NATURE REVIEWS DRUG DISCOVERY
- Fingolimod is a potential novel therapy for multiple sclerosis
- (2010) Orhan Aktas et al. Nature Reviews Neurology
- The secretases: enzymes with therapeutic potential in Alzheimer disease
- (2010) Bart De Strooper et al. Nature Reviews Neurology
- FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation
- (2010) J. W. Choi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Secretase inhibitors and modulators for Alzheimer’s disease treatment
- (2009) Taisuke Tomita Expert Review of Neurotherapeutics
- A Immunotherapy: Intracerebral Sequestration of A by an Anti-A Monoclonal Antibody 266 with High Affinity to Soluble A
- (2009) K. Yamada et al. JOURNAL OF NEUROSCIENCE
- The -Secretase Enzyme BACE in Health and Alzheimer's Disease: Regulation, Cell Biology, Function, and Therapeutic Potential
- (2009) R. Vassar et al. JOURNAL OF NEUROSCIENCE
- Inhibition of γ-Secretase Activity by Helical β-Peptide Foldamers
- (2009) Yuki Imamura et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Pivotal role of cerebral interleukin-17–producing γδT cells in the delayed phase of ischemic brain injury
- (2009) Takashi Shichita et al. NATURE MEDICINE
- The Orphan G Protein-Coupled Receptor 3 Modulates Amyloid-Beta Peptide Generation in Neurons
- (2009) A. Thathiah et al. SCIENCE
- Phosphorylation by Sphingosine Kinase 2 is Essential for in vivo Potency of FTY720 Analogues
- (2008) Klemens Högenauer et al. ChemMedChem
- Phosphoinositides Suppress γ-Secretase in Both the Detergent-soluble and -insoluble States
- (2008) Satoko Osawa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Direct and Potent Regulation of γ-Secretase by Its Lipid Microenvironment
- (2008) Pamela Osenkowski et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Deregulation of sphingolipid metabolism in Alzheimer's disease
- (2008) Xingxuan He et al. NEUROBIOLOGY OF AGING
- "Inside-Out" Signaling of Sphingosine-1-Phosphate: Therapeutic Targets
- (2008) K. Takabe et al. PHARMACOLOGICAL REVIEWS
- FTY720 modulates human oligodendrocyte progenitor process extension and survival
- (2007) Veronique E. Miron et al. ANNALS OF NEUROLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started