Regulation of microglia activation and deactivation by nuclear receptors

Inflammasomes in health and disease

(2012) Till Strowig et al.   NATURE

ApoE-Directed Therapeutics Rapidly Clear  -Amyloid and Reverse Deficits in AD Mouse Models

(2012) P. E. Cramer et al.   SCIENCE

Inflammation: a role for NR4A orphan nuclear receptors?

(2011) Jason P. McMorrow et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

An ADIOL-ERβ-CtBP Transrepression Pathway Negatively Regulates Microglia-Mediated Inflammation

(2011) Kaoru Saijo et al.   CELL

Toll-like receptors in health and disease in the brain: mechanisms and therapeutic potential

(2011) Mark L. Hanke et al.   CLINICAL SCIENCE

The brain tumor microenvironment

(2011) Nikki A. Charles et al.   GLIA

TLR2 Is a Primary Receptor for Alzheimer's Amyloid   Peptide To Trigger Neuroinflammatory Activation

(2011) S. Liu et al.   JOURNAL OF IMMUNOLOGY

TLR4 mutation reduces microglial activation, increases Aβ deposits and exacerbates cognitive deficits in a mouse model of Alzheimer's disease

(2011) Min Song et al.   Journal of Neuroinflammation

Physiology of Microglia

(2011) Helmut Kettenmann et al.   PHYSIOLOGICAL REVIEWS

Microglial glucocorticoid receptors play a pivotal role in regulating dopaminergic neurodegeneration in parkinsonism

(2011) F. Ros-Bernal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toll-like receptor signaling in neural plasticity and disease

(2011) Eitan Okun et al.   TRENDS IN NEUROSCIENCES

Mechanisms Establishing TLR4-Responsive Activation States of Inflammatory Response Genes

(2011) Laure Escoubet-Lozach et al.   PLoS Genetics

HMGB1 and RAGE in Inflammation and Cancer

(2010) Gary P. Sims et al.   Annual Review of Immunology

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Control of Macrophage Activation and Function by PPARs

(2010) Ajay Chawla   CIRCULATION RESEARCH

Intracellular Toll-like Receptors

(2010) Amanda L. Blasius et al.   IMMUNITY

Microglial action in glioma: A boon turns bane

(2010) Anirban Ghosh et al.   IMMUNOLOGY LETTERS

Long-term Cognitive Impairment and Functional Disability Among Survivors of Severe Sepsis

(2010) Theodore J. Iwashyna et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Toll-Like Receptor-3 Agonist Polyinosinic:Polycytidylic Acid Triggers Nigrostriatal Dopaminergic Degeneration

(2010) M. Deleidi et al.   JOURNAL OF NEUROSCIENCE

IL-10 and TGF-β2 are overexpressed in tumor spheres cultured from human gliomas

(2010) Bo Qiu et al.   MOLECULAR BIOLOGY REPORTS

The myeloid cells of the central nervous system parenchyma

(2010) Richard M. Ransohoff et al.   NATURE

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

A Nurr1/CoREST Pathway in Microglia and Astrocytes Protects Dopaminergic Neurons from Inflammation-Induced Death

(2009) Kaoru Saijo et al.   CELL

Apoptotic Cells Promote Their Own Clearance and Immune Tolerance through Activation of the Nuclear Receptor LXR

(2009) Noelia A-Gonzalez et al.   IMMUNITY

CD14 and Toll-Like Receptors 2 and 4 Are Required for Fibrillar A -Stimulated Microglial Activation

(2009) E. G. Reed-Geaghan et al.   JOURNAL OF NEUROSCIENCE

Extracellular histones are major mediators of death in sepsis

(2009) Jun Xu et al.   NATURE MEDICINE

Activation of Liver X Receptors Promotes Neuroprotection and Reduces Brain Inflammation in Experimental Stroke

(2008) Jesús R. Morales et al.   CIRCULATION

Coordination of inflammation and metabolism by PPAR and LXR nuclear receptors

(2008) Cynthia Hong et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Expression of Amyotrophic Lateral Sclerosis-linked SOD1 Mutant Increases the Neurotoxic Potential of Microglia via TLR2

(2008) Yang Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid-β oligomers set fire to inflammasomes and induce Alzheimer's pathology

(2008) Antero Salminen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease

(2008) Jing-Ji Jin et al.   Journal of Neuroinflammation

Toll-Like Receptor 2 Acts as a Natural Innate Immune Receptor to Clear Amyloid  1-42 and Delay the Cognitive Decline in a Mouse Model of Alzheimer's Disease

(2008) K. L. Richard et al.   JOURNAL OF NEUROSCIENCE

Macrophage activation and polarization

(2007) Fernando Oneissi Martinez   Frontiers in Bioscience-Landmark