Genome-wide in vivo screen identifies novel host regulators of metastatic colonization

Functional and molecular characterisation of EO771.LMB tumours, a new C57BL/6-mouse-derived model of spontaneously metastatic mammary cancer

(2015) C. N. Johnstone et al.   Disease Models & Mechanisms

The role of sphingosine-1-phosphate in endothelial barrier function

(2014) Brent A. Wilkerson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Gray platelet syndrome: proinflammatory megakaryocytes and  -granule loss cause myelofibrosis and confer metastasis resistance in mice

(2014) J. A. Guerrero et al.   BLOOD

Sphingosine-1-phosphate receptor 1 signalling in T cells: trafficking and beyond

(2014) Christopher S. Garris et al.   IMMUNOLOGY

Export of sphingosine-1-phosphate and cancer progression

(2014) Kazuaki Takabe et al.   JOURNAL OF LIPID RESEARCH

Ultraviolet-radiation-induced inflammation promotes angiotropism and metastasis in melanoma

(2014) Tobias Bald et al.   NATURE

Full-length RNA-seq from single cells using Smart-seq2

(2014) Simone Picelli et al.   Nature Protocols

Impact of Temporal Variation on Design and Analysis of Mouse Knockout Phenotyping Studies

(2014) Natasha A. Karp et al.   PLoS One

Genome-wide Generation and Systematic Phenotyping of Knockout Mice Reveals New Roles for Many Genes

(2013) Jacqueline K. White et al.   CELL

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

Smart-seq2 for sensitive full-length transcriptome profiling in single cells

(2013) Simone Picelli et al.   NATURE METHODS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Communication between host organism and cancer cells is transduced by systemic sphingosine kinase 1/sphingosine 1-phosphate signalling to regulate tumour metastasis

(2012) Suriyan Ponnusamy et al.   EMBO Molecular Medicine

Spns2, a transporter of phosphorylated sphingoid bases, regulates their blood and lymph levels, and the lymphatic network

(2012) Masayuki Nagahashi et al.   FASEB JOURNAL

The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice

(2012) Shigetomo Fukuhara et al.   JOURNAL OF CLINICAL INVESTIGATION

The Role of Sphingosine-1-Phosphate Transporter Spns2 in Immune System Function

(2012) A. Nijnik et al.   JOURNAL OF IMMUNOLOGY

Spontaneous mutation of the Dock2 gene in Irf5-/- mice complicates interpretation of type I interferon production and antibody responses

(2012) W. E. Purtha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Transporter Spns2 Is Required for Secretion of Lymph but Not Plasma Sphingosine-1-Phosphate

(2012) Alejandra Mendoza et al.   Cell Reports

Targeted inhibition of mitochondrial Hsp90 suppresses localised and metastatic prostate cancer growth in a genetic mouse model of disease

(2011) B H Kang et al.   BRITISH JOURNAL OF CANCER

P-Rex1 is required for efficient melanoblast migration and melanoma metastasis

(2011) Colin R. Lindsay et al.   Nature Communications

CD39/ENTPD1 Expression by CD4+Foxp3+ Regulatory T Cells Promotes Hepatic Metastatic Tumor Growth in Mice

(2010) Xiaofeng Sun et al.   GASTROENTEROLOGY

An improved Flp deleter mouse in C57Bl/6 based on Flpo recombinase

(2010) Andrea Kranz et al.   GENESIS

The S1P1-mTOR axis directs the reciprocal differentiation of TH1 and Treg cells

(2010) Guangwei Liu et al.   NATURE IMMUNOLOGY

Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

(2010) Carol Kilkenny et al.   PLOS BIOLOGY

Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning

(2009) Trung H.M. Pham et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antigen Specificity Determines the Pro- or Antitumoral Nature of CD8+ T Cells

(2009) S. Cuff et al.   JOURNAL OF IMMUNOLOGY

Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate

(2009) N. C. Hait et al.   SCIENCE