标题
Genetic Alterations of TRAF Proteins in Human Cancers
作者
关键词
-
出版物
Frontiers in Immunology
Volume 9, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2018-09-20
DOI
10.3389/fimmu.2018.02111
参考文献
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- TRAF2 is an NF-κB-activating oncogene in epithelial cancers
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- Downregulation of TRAF2 Mediates NIK-Induced Pancreatic Cancer Cell Proliferation and Tumorigenicity
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- Genomic Analysis of Non-NF2 Meningiomas Reveals Mutations in TRAF7, KLF4, AKT1, and SMO
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- Integrative Genomic Characterization of Oral Squamous Cell Carcinoma Identifies Frequent Somatic Drivers
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- The Genetic Landscape of Clinical Resistance to RAF Inhibition in Metastatic Melanoma
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- IKKε-Mediated Tumorigenesis Requires K63-Linked Polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 Ubiquitin Ligase Complex
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- TRAF4 Is a Novel Phosphoinositide-Binding Protein Modulating Tight Junctions and Favoring Cell Migration
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- Attenuation of TNFSF10/TRAIL-induced apoptosis by an autophagic survival pathway involving TRAF2- and RIPK1/RIP1-mediated MAPK8/JNK activation
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- Genetic lesions of the TRAF3 and MAP3K14 genes in classical Hodgkin lymphoma
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- A Landscape of Driver Mutations in Melanoma
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- Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing
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- NLRP12 Suppresses Colon Inflammation and Tumorigenesis through the Negative Regulation of Noncanonical NF-κB Signaling
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- Tumor Necrosis Factor (TNF) Receptor-associated Factor 7 Is Required for TNFα-induced Jun NH2-terminal Kinase Activation and Promotes Cell Death by Regulating Polyubiquitination and Lysosomal Degradation of c-FLIP Protein
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- Opposing Roles for TRAF1 in the AlternativeversusClassical NF-κB Pathway in T Cells
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- Tumor Necrosis Factor Receptor-associated Factor Family Protein 2 Is a Key Mediator of the Epidermal Growth Factor-induced Ribosomal S6 Kinase 2/cAMP-responsive Element-binding Protein/Fos Protein Signaling Pathway
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- The coding genome of splenic marginal zone lymphoma: activation ofNOTCH2and other pathways regulating marginal zone development
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- TNFR-Associated Factor 2 Deficiency in B Lymphocytes Predisposes to Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma in Mice
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- Identification of Molecular Pathway Aberrations in Uterine Serous Carcinoma by Genome-wide Analyses
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- The E3 Ubiquitin Ligase TRAF6 Intercedes in Starvation-Induced Skeletal Muscle Atrophy through Multiple Mechanisms
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- Reciprocal Interaction between TRAF6 and Notch Signaling Regulates Adult Myofiber Regeneration upon Injury
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- I B Kinase Phosphorylates TRAF2 To Promote Mammary Epithelial Cell Transformation
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- Numbl inhibits glioma cell migration and invasion by suppressing TRAF5-mediated NF-κB activation
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- TRAF2 Sets a Threshold for Extrinsic Apoptosis by Tagging Caspase-8 with a Ubiquitin Shutoff Timer
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- Recurrent R-spondin fusions in colon cancer
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- The mutational landscape of lethal castration-resistant prostate cancer
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- The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
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- OX40 signaling favors the induction of TH9 cells and airway inflammation
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- Autocrine IL-1β-TRAF6 signalling promotes squamous cell carcinoma invasion through paracrine TNFα signalling to carcinoma-associated fibroblasts
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- Downregulation of ubiquitin E3 ligase TNF receptor-associated factor 7 leads to stabilization of p53 in breast cancer
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- In Vivo Evidence That TRAF4 Is Required for Central Nervous System Myelin Homeostasis
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- Deletion of cIAP1 and cIAP2 in murine B lymphocytes constitutively activates cell survival pathways and inactivates the germinal center response
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- TRAF6 directs commitment to regulatory T cells in thymocytes
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- TRAF7 Protein Promotes Lys-29-linked Polyubiquitination of IκB Kinase (IKKγ)/NF-κB Essential Modulator (NEMO) and p65/RelA Protein and Represses NF-κB Activation
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- Tumor Necrosis Factor Receptor-associated Factor (TRAF) 2 Controls Homeostasis of the Colon to Prevent Spontaneous Development of Murine Inflammatory Bowel Disease
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- The seventh ring: Exploring TRAF7 functions
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- TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer
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- Loss of the signaling adaptor TRAF1 causes CD8+T cell dysregulation during human and murine chronic infection
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- Keratinocyte sensitization to tumour necrosis factor-induced nuclear factor kappa B activation by the E2 regulatory protein of human papillomaviruses
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- Enhanced Toll-like receptor (TLR) responses of TNFR-associated factor 3 (TRAF3)-deficient B lymphocytes
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- Specific deletion of TRAF3 in B lymphocytes leads to B-lymphoma development in mice
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- Analysis of the coding genome of diffuse large B-cell lymphoma
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- Distinct patterns of somatic alterations in a lymphoblastoid and a tumor genome derived from the same individual
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- Epstein-Barr Virus Latent Membrane Protein 1 Modulates Distinctive NF- B Pathways through C-Terminus-Activating Region 1 To Regulate Epidermal Growth Factor Receptor Expression
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- Lysine 63 Polyubiquitination in Immunotherapy and in Cancer-promoting Inflammation
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- TRAF1 is involved in the classical NF-κB activation and CD30-induced alternative activity in Hodgkin's lymphoma cells
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- The E3 Ligase TRAF6 Regulates Akt Ubiquitination and Activation
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- Involvement of endoplasmic reticulum stress in Docetaxel-induced JNK-dependent apoptosis of human melanoma
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- Lymphocyte-specific TRAF3 transgenic mice have enhanced humoral responses and develop plasmacytosis, autoimmunity, inflammation, and cancer
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- The Signaling Adaptor p62 Is an Important NF-κB Mediator in Tumorigenesis
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- Growth Inhibition and Radiosensitization of Glioblastoma and Lung Cancer Cells by Small Interfering RNA Silencing of Tumor Necrosis Factor Receptor-Associated Factor 2
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- TRAF2 and TRAF3 Signal Adapters Act Cooperatively to Control the Maturation and Survival Signals Delivered to B Cells by the BAFF Receptor
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- Characterization of immune functions in TRAF4-deficient mice
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- Comprehensive genomic characterization defines human glioblastoma genes and core pathways
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- Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-κB signaling
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- Noncanonical NF-κB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK
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- Viruses associated with human cancer
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