The E3 Ubiquitin Ligase TRAF6 Intercedes in Starvation-Induced Skeletal Muscle Atrophy through Multiple Mechanisms

The Unfolded Protein Response Mediates Adaptation to Exercise in Skeletal Muscle through a PGC-1α/ATF6α Complex

(2011) Jun Wu et al.   Cell Metabolism

Identification of Genes that Elicit Disuse Muscle Atrophy via the Transcription Factors p50 and Bcl-3

(2011) Chia-Ling Wu et al.   PLoS One

Fasting-related autophagic response in slow- and fast-twitch skeletal muscle

(2010) Tomonori Ogata et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondrial fission and remodelling contributes to muscle atrophy

(2010) Vanina Romanello et al.   EMBO JOURNAL

Autophagy in skeletal muscle

(2010) Marco Sandri   FEBS LETTERS

The TWEAK–Fn14 system is a critical regulator of denervation-induced skeletal muscle atrophy in mice

(2010) Ashwani Mittal et al.   JOURNAL OF CELL BIOLOGY

Targeted ablation of TRAF6 inhibits skeletal muscle wasting in mice

(2010) Pradyut K. Paul et al.   JOURNAL OF CELL BIOLOGY

The Transcription Factor ATF4 Promotes Skeletal Myofiber Atrophy during Fasting

(2010) Scott M. Ebert et al.   MOLECULAR ENDOCRINOLOGY

TRAF6 and A20 Regulate Lysine 63-Linked Ubiquitination of Beclin-1 to Control TLR4-Induced Autophagy

(2010) C. S. Shi et al.   Science Signaling

Regulation of TNFRSF and innate immune signalling complexes by TRAFs and cIAPs

(2009) J Silke et al.   CELL DEATH AND DIFFERENTIATION

Translation Attenuation through eIF2α Phosphorylation Prevents Oxidative Stress and Maintains the Differentiated State in β Cells

(2009) Sung Hoon Back et al.   Cell Metabolism

Autophagy Is Required to Maintain Muscle Mass

(2009) Eva Masiero et al.   Cell Metabolism

PB1 Domain Interaction of p62/Sequestosome 1 and MEKK3 Regulates NF-κB Activation

(2009) Kazuhiro Nakamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation

(2009) Shenhav Cohen et al.   JOURNAL OF CELL BIOLOGY

Activation of the Akt-NF- B Pathway by Subtilase Cytotoxin through the ATF6 Branch of the Unfolded Protein Response

(2009) H. Yamazaki et al.   JOURNAL OF IMMUNOLOGY

The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis

(2009) Yiguo Wang et al.   NATURE

The E3 Ligase TRAF6 Regulates Akt Ubiquitination and Activation

(2009) W.-L. Yang et al.   SCIENCE

ATF4-dependent transcription mediates signaling of amino acid limitation

(2009) Michael S. Kilberg et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Dephosphorylation of Translation Initiation Factor 2α Enhances Glucose Tolerance and Attenuates Hepatosteatosis in Mice

(2008) Seiichi Oyadomari et al.   Cell Metabolism

UPR Pathways Combine to Prevent Hepatic Steatosis Caused by ER Stress-Mediated Suppression of Transcriptional Master Regulators

(2008) D. Thomas Rutkowski et al.   DEVELOPMENTAL CELL

The RING Domain and First Zinc Finger of TRAF6 Coordinate Signaling by Interleukin-1, Lipopolysaccharide, and RANKL

(2008) Betty Lamothe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear factor-kappa B signaling in skeletal muscle atrophy

(2008) Hong Li et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

TRAF6 Mediates Smad-Independent Activation of JNK and p38 by TGF-β

(2008) Motozo Yamashita et al.   MOLECULAR CELL

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

(2008) Inki Kim et al.   NATURE REVIEWS DRUG DISCOVERY

TRAF6 Autoubiquitination-Independent Activation of the NFκB and MAPK Pathways in Response to IL-1 and RANKL

(2008) Matthew C. Walsh et al.   PLoS One

Regulation of Hepatic Lipogenesis by the Transcription Factor XBP1

(2008) A.-H. Lee et al.   SCIENCE