A novel patient-derived tumorgraft model with TRAF1-ALK anaplastic large-cell lymphoma translocation

Gene expression signatures delineate biological and prognostic subgroups in peripheral T-cell lymphoma

(2014) J. Iqbal et al.   BLOOD

Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas

(2014) Teresa Palomero et al.   NATURE GENETICS

The Potent Oncogene NPM-ALK Mediates Malignant Transformation of Normal Human CD4 + T Lymphocytes

(2013) Qian Zhang et al.   AMERICAN JOURNAL OF PATHOLOGY

PRDM1/BLIMP1 is commonly inactivated in anaplastic large T-cell lymphoma

(2013) M. Boi et al.   BLOOD

Genome-wide high resolution DNA profiling of hairy cell leukaemia

(2013) Andrea Rinaldi et al.   BRITISH JOURNAL OF HAEMATOLOGY

NovelTRAF1-ALKfusion identified by deep RNA sequencing of anaplastic large cell lymphoma

(2013) Andrew L. Feldman et al.   GENES CHROMOSOMES & CANCER

The PD-1/PD-L1 axis contributes to T-cell dysfunction in chronic lymphocytic leukemia

(2013) D. Brusa et al.   HAEMATOLOGICA

Dual ALK and MYC Rearrangements Leading to an Aggressive Variant of Anaplastic Large Cell Lymphoma

(2013) Xiayuan Liang et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Bellerophontes: an RNA-Seq data analysis framework for chimeric transcripts discovery based on accurate fusion model

(2012) F. Abate et al.   BIOINFORMATICS

Genome-wide analysis reveals recurrent structural abnormalities of TP63 and other p53-related genes in peripheral T-cell lymphomas

(2012) G. Vasmatzis et al.   BLOOD

Identification of a 3-gene model as a powerful diagnostic tool for the recognition of ALK-negative anaplastic large-cell lymphoma

(2012) L. Agnelli et al.   BLOOD

Anaplastic large cell lymphoma, ALK-positive

(2012) Andrés J.M. Ferreri et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Preclinical activity of LBH589 alone or in combination with chemotherapy in a xenogeneic mouse model of human acute lymphoblastic leukemia

(2012) A Vilas-Zornoza et al.   LEUKEMIA

PDGFR blockade is a rational and effective therapy for NPM-ALK–driven lymphomas

(2012) Daniela Laimer et al.   NATURE MEDICINE

Patient-derived tumour xenografts as models for oncology drug development

(2012) John J. Tentler et al.   Nature Reviews Clinical Oncology

Transforming Fusions of FGFR and TACC Genes in Human Glioblastoma

(2012) D. Singh et al.   SCIENCE

ALK signaling and target therapy in anaplastic large cell lymphoma

(2012) Fabrizio Tabbó   Frontiers in Oncology

ChimeraScan: a tool for identifying chimeric transcription in sequencing data

(2011) Matthew K. Iyer et al.   BIOINFORMATICS

Clonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapse

(2011) Emmanuelle Clappier et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Anaplastic lymphoma kinase in human cancer

(2011) Antonella Barreca et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

CEP-28122, a Highly Potent and Selective Orally Active Inhibitor of Anaplastic Lymphoma Kinase with Antitumor Activity in Experimental Models of Human Cancers

(2011) M. Cheng et al.   MOLECULAR CANCER THERAPEUTICS

Context-Specific Regulation of NF-κB Target Gene Expression by EZH2 in Breast Cancers

(2011) Shuet Theng Lee et al.   MOLECULAR CELL

deFuse: An Algorithm for Gene Fusion Discovery in Tumor RNA-Seq Data

(2011) Andrew McPherson et al.   PLoS Computational Biology

C-MYC rearrangement may induce an aggressive phenotype in anaplastic lymphoma kinase positive anaplastic large cell lymphoma: Identification of a novel fusion gene ALO17/C-MYC

(2010) Hiroshi Moritake et al.   AMERICAN JOURNAL OF HEMATOLOGY

Treatment and prognosis of mature T-cell and NK-cell lymphoma: an analysis of patients with T-cell lymphoma treated in studies of the German High-Grade Non-Hodgkin Lymphoma Study Group

(2010) N. Schmitz et al.   BLOOD

Gene Expression Profiling Uncovers Molecular Classifiers for the Recognition of Anaplastic Large-Cell Lymphoma Within Peripheral T-Cell Neoplasms

(2010) Roberto Piva et al.   JOURNAL OF CLINICAL ONCOLOGY

TNF Activates a NF- B-Regulated Cellular Program in Human CD45RA- Regulatory T Cells that Modulates Their Suppressive Function

(2010) M. Nagar et al.   JOURNAL OF IMMUNOLOGY

Increased signaling through p62 in the marrow microenvironment increases myeloma cell growth and osteoclast formation

(2009) Y. Hiruma et al.   BLOOD

Bortezomib induces canonical nuclear factor- B activation in multiple myeloma cells

(2009) T. Hideshima et al.   BLOOD

Anaplastic large cell lymphoma: changes in the World Health Organization classification and perspectives for targeted therapy

(2009) B. Falini et al.   HAEMATOLOGICA

Gene expression profiling of isolated tumour cells from anaplastic large cell lymphomas: insights into its cellular origin, pathogenesis and relation to Hodgkin lymphoma

(2009) S Eckerle et al.   LEUKEMIA

Mutations of multiple genes cause deregulation of NF-κB in diffuse large B-cell lymphoma

(2009) Mara Compagno et al.   NATURE

ALK- anaplastic large-cell lymphoma is clinically and immunophenotypically different from both ALK+ ALCL and peripheral T-cell lymphoma, not otherwise specified: report from the International Peripheral T-Cell Lymphoma Project

(2008) K. J. Savage et al.   BLOOD

The enzymatic activity of 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase is enhanced by NPM-ALK: new insights in ALK-mediated pathogenesis and the treatment of ALCL

(2008) F. E. Boccalatte et al.   BLOOD

From Human to Mouse and Back: 'Tumorgraft' Models Surge in Popularity

(2008) K. Garber   JNCI-Journal of the National Cancer Institute

Efficient tumour formation by single human melanoma cells

(2008) Elsa Quintana et al.   NATURE

Stromal Gene Signatures in Large-B-Cell Lymphomas

(2008) G. Lenz et al.   NEW ENGLAND JOURNAL OF MEDICINE