The coding genome of splenic marginal zone lymphoma: activation ofNOTCH2and other pathways regulating marginal zone development

Early Growth Response Genes Regulate B Cell Development, Proliferation, and Immune Response

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Over 30% of patients with splenic marginal zone lymphoma express the same immunoglobulin heavy variable gene: ontogenetic implications

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Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

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Splenic marginal zone lymphoma with VH1-02 gene rearrangement expresses poly- and self-reactive antibodies with similar reactivity

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CD19-independent instruction of murine marginal zone B-cell development by constitutive Notch2 signaling

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Whole transcriptome sequencing reveals recurrent NOTCH1 mutations in mantle cell lymphoma

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Alteration of BIRC3 and multiple other NF- B pathway genes in splenic marginal zone lymphoma

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CD73-generated extracellular adenosine in chronic lymphocytic leukemia creates local conditions counteracting drug-induced cell death

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Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia

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Simple genetic diagnosis of hairy cell leukemia by sensitive detection of the BRAF-V600E mutation

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Splenic marginal zone B-cell lymphoma

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Fine tuning of IRF-4 expression by SWAP-70 controls the initiation of plasma cell development

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BCR and TLR signaling pathways are recurrently targeted by genetic changes in splenic marginal zone lymphomas

(2011) Q. Yan et al.   HAEMATOLOGICA

Transcriptional Repression in the Notch Pathway

(2011) Bradley D. VanderWielen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analysis of the chronic lymphocytic leukemia coding genome: role ofNOTCH1mutational activation

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CREBBP mutations in relapsed acute lymphoblastic leukaemia

(2011) Charles G. Mullighan et al.   NATURE

Inactivating mutations of acetyltransferase genes in B-cell lymphoma

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Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

(2011) Ryan D. Morin et al.   NATURE

Analysis of the coding genome of diffuse large B-cell lymphoma

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Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder

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Mutations in NOTCH2 cause Hajdu-Cheney syndrome, a disorder of severe and progressive bone loss

(2011) Michael A Simpson et al.   NATURE GENETICS

Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia

(2011) Víctor Quesada et al.   NATURE GENETICS

Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery

(2011) Jasmeen Oberoi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

SF3B1and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia

(2011) Lili Wang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Molecular Characterization of the Region 7q22.1 in Splenic Marginal Zone Lymphomas

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Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma

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Functions of Notch Signaling in the Immune System: Consensus and Controversies

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Cytogenetic aberrations and their prognostic value in a series of 330 splenic marginal zone B-cell lymphomas: a multicenter study of the Splenic B-Cell Lymphoma Group

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Genome-wide DNA profiling of marginal zone lymphomas identifies subtype-specific lesions with an impact on the clinical outcome

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B cells lacking the tumor suppressor TNFAIP3/A20 display impaired differentiation and hyperactivation and cause inflammation and autoimmunity in aged mice

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Constitutive Canonical NF-κB Activation Cooperates with Disruption of BLIMP1 in the Pathogenesis of Activated B Cell-like Diffuse Large Cell Lymphoma

(2010) Dinis Pedro Calado et al.   CANCER CELL

SWAP-70 controls formation of the splenic marginal zone through regulating T1B-cell differentiation

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Oncogenically active MYD88 mutations in human lymphoma

(2010) Vu N. Ngo et al.   NATURE

ARID1AMutations in Endometriosis-Associated Ovarian Carcinomas

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COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

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The Genetic Landscape of the Childhood Cancer Medulloblastoma

(2010) D. W. Parsons et al.   SCIENCE

Non-Canonical NF-κB Activation and Abnormal B Cell Accumulation in Mice Expressing Ubiquitin Protein Ligase-Inactive c-IAP2

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Sin3: Master scaffold and transcriptional corepressor

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Gain-of-function mutations and copy number increases of Notch2 in diffuse large B-cell lymphoma

(2009) Suk-young Lee et al.   CANCER SCIENCE

NOTCH2 mutations in marginal zone lymphoma

(2008) G. Troen et al.   HAEMATOLOGICA

TBL1 and TBLR1 Phosphorylation on Regulated Gene Promoters Overcomes Dual CtBP and NCoR/SMRT Transcriptional Repression Checkpoints

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γ-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia

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NIK overexpression amplifies, whereas ablation of its TRAF3-binding domain replaces BAFF:BAFF-R-mediated survival signals in B cells

(2008) Y. Sasaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oncogenic CARD11 Mutations in Human Diffuse Large B Cell Lymphoma

(2008) G. Lenz et al.   SCIENCE