EGFR phosphorylation of DCBLD2 recruits TRAF6 and stimulates AKT-promoted tumorigenesis

Transmembrane protein ESDN promotes endothelial VEGF signaling and regulates angiogenesis

(2013) Lei Nie et al.   JOURNAL OF CLINICAL INVESTIGATION

Recent molecular discoveries in angiogenesis and antiangiogenic therapies in cancer

(2013) Jonathan Welti et al.   JOURNAL OF CLINICAL INVESTIGATION

Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor–Resistant Disease

(2013) Kadoaki Ohashi et al.   JOURNAL OF CLINICAL ONCOLOGY

RETRACTED ARTICLE: TNF receptor-associated factor 6 regulates proliferation, apoptosis, and invasion of glioma cells

(2013) Zhang Peng et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Nanofiber-mediated inhibition of focal adhesion kinase sensitizes glioma stemlike cells to epidermal growth factor receptor inhibition

(2013) Maya Srikanth et al.   NEURO-ONCOLOGY

Ensemble of Gene Signatures Identifies Novel Biomarkers in Colorectal Cancer Activated through PPARγ and TNFα Signaling

(2013) Stefano Maria Pagnotta et al.   PLoS One

Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3

(2013) P. Mao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Skp2-SCF E3 Ligase Regulates Akt Ubiquitination, Glycolysis, Herceptin Sensitivity, and Tumorigenesis

(2012) Chia-Hsin Chan et al.   CELL

Targeting the EGFR signaling pathway in cancer therapy

(2012) Parthasarathy Seshacharyulu et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Emerging insights into the molecular and cellular basis of glioblastoma

(2012) G. P. Dunn et al.   GENES & DEVELOPMENT

TRAF6 Protein Couples Toll-like Receptor 4 Signaling to Src Family Kinase Activation and Opening of Paracellular Pathway in Human Lung Microvascular Endothelia

(2012) Anguo Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

P14ARF inhibits human glioblastoma–induced angiogenesis by upregulating the expression of TIMP3

(2012) Abdessamad Zerrouqi et al.   JOURNAL OF CLINICAL INVESTIGATION

DCBLD2 Gene Variations Correlate with Nasal Polyposis in Korean Asthma Patients

(2012) Charisse Flerida A. Pasaje et al.   LUNG

ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect

(2012) Weiwei Yang et al.   NATURE CELL BIOLOGY

Phosphorylation of dedicator of cytokinesis 1 (Dock180) at tyrosine residue Y722 by Src family kinases mediates EGFRvIII-driven glioblastoma tumorigenesis

(2012) H. Feng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of TRAF6 on the biological behavior of human lung adenocarcinoma cell

(2012) Lou Zhong et al.   TUMOR BIOLOGY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

SHP-2/PTPN11 mediates gliomagenesis driven by PDGFRA and INK4A/ARF aberrations in mice and humans

(2011) Kun-Wei Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer

(2011) Daniel T. Starczynowski et al.   JOURNAL OF CLINICAL INVESTIGATION

Activation of Rac1 by Src-dependent phosphorylation of Dock180Y1811 mediates PDGFRα-stimulated glioma tumorigenesis in mice and humans

(2011) Haizhong Feng et al.   JOURNAL OF CLINICAL INVESTIGATION

Platelet-derived growth factor receptor alpha in glioma: a bad seed

(2011) Kun-Wei Liu et al.   Chinese Journal of Cancer

Therapeutic targeting of epidermal growth factor receptor in human cancer: successes and limitations

(2011) Jill Wykosky et al.   Chinese Journal of Cancer

Exciting New Advances in Neuro-Oncology: The Avenue to a Cure for Malignant Glioma

(2010) E. G. Van Meir et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma

(2010) M.-d.-M. Inda et al.   GENES & DEVELOPMENT

Epidermal growth factor receptor targeted therapy of squamous cell carcinoma of the head and neck

(2010) Mark E. Sharafinski et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

TRAF6 is autoinhibited by an intramolecular interaction which is counteracted by trans-ubiquitination

(2010) Kent Z.Q. Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

ZD6474, a Multitargeted Inhibitor for Receptor Tyrosine Kinases, Suppresses Growth of Gliomas Expressing an Epidermal Growth Factor Receptor Mutant, EGFRvIII, in the Brain

(2010) Jia-Jean Yiin et al.   MOLECULAR CANCER THERAPEUTICS

Targeting the EGFR and the PKB pathway in cancer

(2009) Shoshana Klein et al.   CURRENT OPINION IN CELL BIOLOGY

Endothelial and Smooth Muscle-derived Neuropilin-like Protein Regulates Platelet-derived Growth Factor Signaling in Human Vascular Smooth Muscle Cells by Modulating Receptor Ubiquitination

(2009) Xiaojia Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The E3 Ligase TRAF6 Regulates Akt Ubiquitination and Activation

(2009) W.-L. Yang et al.   SCIENCE

Identification of novel neuroendocrine-specific tumour genes

(2008) E Hofsli et al.   BRITISH JOURNAL OF CANCER

Epigenetic Down-Regulation and Suppressive Role of DCBLD2 in Gastric Cancer Cell Proliferation and Invasion

(2008) M. Kim et al.   MOLECULAR CANCER RESEARCH

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

Signaling networks assembled by oncogenic EGFR and c-Met

(2008) A. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA