Monocytes and macrophages as nanomedicinal targets for improved diagnosis and treatment of disease

Nr4a1-Dependent Ly6Clow Monocytes Monitor Endothelial Cells and Orchestrate Their Disposal

(2013) Leo M. Carlin et al.   CELL

Multifunctional Gold Nanoparticles for Diagnosis and Therapy of Disease

(2013) Aneta J. Mieszawska et al.   MOLECULAR PHARMACEUTICS

Leukocyte Behavior in Atherosclerosis, Myocardial Infarction, and Heart Failure

(2013) F. K. Swirski et al.   SCIENCE

The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems

(2012) Alexandre Albanese et al.   Annual Review of Biomedical Engineering

Nanobody-Based Targeting of the Macrophage Mannose Receptor for EffectiveIn VivoImaging of Tumor-Associated Macrophages

(2012) Kiavash Movahedi et al.   CANCER RESEARCH

Surface functionalization of nanoparticles for nanomedicine

(2012) Rubul Mout et al.   CHEMICAL SOCIETY REVIEWS

Ly6Chi Monocytes in the Inflamed Colon Give Rise to Proinflammatory Effector Cells and Migratory Antigen-Presenting Cells

(2012) Ehud Zigmond et al.   IMMUNITY

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

(2012) Simon Yona et al.   IMMUNITY

Early window of diabetes determinism in NOD mice, dependent on the complement receptor CRIg, identified by noninvasive imaging

(2012) Wenxian Fu et al.   NATURE IMMUNOLOGY

Origins of tumor-associated macrophages and neutrophils

(2012) V. Cortez-Retamozo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting monocytes/macrophages in the treatment of rheumatoid arthritis

(2012) J.-L. Davignon et al.   RHEUMATOLOGY

Preclinical Development and Clinical Translation of a PSMA-Targeted Docetaxel Nanoparticle with a Differentiated Pharmacological Profile

(2012) J. Hrkach et al.   Science Translational Medicine

Carcinoma origin dictates differential skewing of monocyte function

(2012) Marijn Bögels et al.   OncoImmunology

Protein Cage Nanoparticles Bearing the LyP-1 Peptide for Enhanced Imaging of Macrophage-Rich Vascular Lesions

(2011) Masaki Uchida et al.   ACS Nano

Nanoparticle Delivery of Cancer Drugs

(2011) Andrew Z. Wang et al.   Annual Review of Medicine

Tuberculosis Pathogenesis and Immunity

(2011) Jennifer A. Philips et al.   Annual Review of Pathology-Mechanisms of Disease

Detection of Macrophages in Aortic Aneurysms by Nanoparticle Positron Emission Tomography–Computed Tomography

(2011) Matthias Nahrendorf et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Folate-targeted nanoparticles show efficacy in the treatment of inflammatory arthritis

(2011) Thommey P. Thomas et al.   ARTHRITIS AND RHEUMATISM

89Zr-Labeled Dextran Nanoparticles Allow in Vivo Macrophage Imaging

(2011) Edmund J. Keliher et al.   BIOCONJUGATE CHEMISTRY

Macrophages in the Pathogenesis of Atherosclerosis

(2011) Kathryn J. Moore et al.   CELL

MRI of Tumor-Associated Macrophages with Clinically Applicable Iron Oxide Nanoparticles

(2011) H. E. Daldrup-Link et al.   CLINICAL CANCER RESEARCH

Osteoclast Activity and Subtypes as a Function of Physiology and Pathology—Implications for Future Treatments of Osteoporosis

(2011) K. Henriksen et al.   ENDOCRINE REVIEWS

Macrophages in skin injury and repair

(2011) Babak Mahdavian Delavary et al.   IMMUNOBIOLOGY

Progress and challenges in translating the biology of atherosclerosis

(2011) Peter Libby et al.   NATURE

Therapeutic siRNA silencing in inflammatory monocytes in mice

(2011) Florian Leuschner et al.   NATURE BIOTECHNOLOGY

Atherosclerosis: current pathogenesis and therapeutic options

(2011) Christian Weber et al.   NATURE MEDICINE

Perspectives and opportunities for nanomedicine in the management of atherosclerosis

(2011) Mark E. Lobatto et al.   NATURE REVIEWS DRUG DISCOVERY

No Need to Coax Monocytes

(2011) G. J. Randolph   SCIENCE

Target-specific delivery of peptide-based probes for PET imaging

(2010) Kai Chen et al.   ADVANCED DRUG DELIVERY REVIEWS

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

Identification of a Novel Macrophage Phenotype That Develops in Response to Atherogenic Phospholipids via Nrf2

(2010) Alexandra Kadl et al.   CIRCULATION RESEARCH

Noninvasive imaging of pancreatic islet inflammation in type 1A diabetes patients

(2010) Jason L. Gaglia et al.   JOURNAL OF CLINICAL INVESTIGATION

Physicochemical parameters affecting liposomal bisphosphonates bioactivity for restenosis therapy: Internalization, cell inhibition, activation of cytokines and complement, and mechanism of cell death

(2010) Hila Epstein-Barash et al.   JOURNAL OF CONTROLLED RELEASE

Tumor-associated macrophages infiltration is associated with peritumoral lymphangiogenesis and poor prognosis in lung adenocarcinoma

(2010) Bi Cheng Zhang et al.   MEDICAL ONCOLOGY

Multimodal Clinical Imaging To Longitudinally Assess a Nanomedical Anti-Inflammatory Treatment in Experimental Atherosclerosis

(2010) Mark E. Lobatto et al.   MOLECULAR PHARMACEUTICS

Doxorubicin-conjugated quantum dots to target alveolar macrophages and inflammation

(2010) Krishnan V. Chakravarthy et al.   Nanomedicine-Nanotechnology Biology and Medicine

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

(2010) Subhra K Biswas et al.   NATURE IMMUNOLOGY

Delivering nanomedicine to solid tumors

(2010) Rakesh K. Jain et al.   Nature Reviews Clinical Oncology

Strategies in the design of nanoparticles for therapeutic applications

(2010) Robby A. Petros et al.   NATURE REVIEWS DRUG DISCOVERY

Targeting nanoparticles to cancer

(2010) M. Wang et al.   PHARMACOLOGICAL RESEARCH

Macrophages: Master Regulators of Inflammation and Fibrosis

(2010) Thomas Wynn et al.   SEMINARS IN LIVER DISEASE

A Light-Activated Theranostic Nanoagent for Targeted Macrophage Ablation in Inflammatory Atherosclerosis

(2010) Jason R. McCarthy et al.   Small

Immune and Inflammatory Mechanisms of Atherosclerosis

(2009) Elena Galkina et al.   Annual Review of Immunology

Regulation of the Migration and Survival of Monocyte Subsets by Chemokine Receptors and Its Relevance to Atherosclerosis

(2009) Emmanuel L. Gautier et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Biodegradable polymeric nanoparticles based drug delivery systems

(2009) Avnesh Kumari et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Monocytes: subsets, origins, fates and functions

(2009) Simon Yona et al.   CURRENT OPINION IN HEMATOLOGY

Nanoparticle-based targeted drug delivery

(2009) Rajesh Singh et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

The role of macrophages in inflammatory bowel diseases

(2009) Sigrid E.M. Heinsbroek et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Superparamagnetic Iron Oxide Nanoparticles: Diagnostic Magnetic Resonance Imaging and Potential Therapeutic Applications in Neurooncology and Central Nervous System Inflammatory Pathologies, a Review

(2009) Jason S Weinstein et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease

(2009) Andrew M. Smith et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites

(2009) F. K. Swirski et al.   SCIENCE

Dendrimer-based nanoparticles for cancer therapy

(2009) J. R. Baker   Hematology-American Society of Hematology Education Program

Nanoshell-Enabled Photothermal Cancer Therapy: Impending Clinical Impact

(2008) Surbhi Lal et al.   ACCOUNTS OF CHEMICAL RESEARCH

Mannan-coated gelatin nanoparticles for sustained and targeted delivery of didanosine: In vitro and in vivo evaluation

(2008) Amandeep Kaur et al.   ACTA PHARMACEUTICA

Nanotechnology in Medical Imaging

(2008) David P. Cormode et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The inflammatory chemokines CCL2 and CCL5 in breast cancer

(2008) Gali Soria et al.   CANCER LETTERS

“Re-educating” tumor-associated macrophages by targeting NF-κB

(2008) Thorsten Hagemann et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Enhanced Anti-Inflammation of Inhaled Dexamethasone Palmitate Using Mannosylated Liposomes in an Endotoxin-Induced Lung Inflammation Model

(2008) W. Wijagkanalan et al.   MOLECULAR PHARMACOLOGY

Chitosan/siRNA Nanoparticle–mediated TNF-α Knockdown in Peritoneal Macrophages for Anti-inflammatory Treatment in a Murine Arthritis Model

(2008) Kenneth A Howard et al.   MOLECULAR THERAPY

Nanocrystal Core High-Density Lipoproteins: A Multimodality Contrast Agent Platform

(2008) David P. Cormode et al.   NANO LETTERS

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE

Nanoparticle PET-CT Imaging of Macrophages in Inflammatory Atherosclerosis

(2007) Matthias Nahrendorf et al.   CIRCULATION

Macrophage activation by endogenous danger signals

(2007) X Zhang et al.   JOURNAL OF PATHOLOGY