Perspectives and opportunities for nanomedicine in the management of atherosclerosis

Immunosuppressive Therapy with Oral Prednisone to Prevent Restenosis after PCI. A Multicenter Randomized Trial

(2011) Flavio Ribichini et al.   AMERICAN JOURNAL OF MEDICINE

Detection of Macrophages in Aortic Aneurysms by Nanoparticle Positron Emission Tomography–Computed Tomography

(2011) Matthias Nahrendorf et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Report of the National Heart, Lung, and Blood Institute Working Group on the Translation of Cardiovascular Molecular Imaging

(2011) Denis B. Buxton et al.   CIRCULATION

Cardiovascular Molecular Imaging

(2011) Ian Y. Chen et al.   CIRCULATION

Molecular Imaging of Coronary Atherosclerosis and Myocardial Infarction

(2011) Florian Leuschner et al.   CIRCULATION RESEARCH

The Pathology of Neoatherosclerosis in Human Coronary Implants

(2011) Gaku Nakazawa et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Thrombin-inhibiting perfluorocarbon nanoparticles provide a novel strategy for the treatment and magnetic resonance imaging of acute thrombosis

(2011) J. MYERSON et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Biomimetic High Density Lipoprotein Nanoparticles For Nucleic Acid Delivery

(2011) Kaylin M. McMahon et al.   NANO LETTERS

Progress and challenges in translating the biology of atherosclerosis

(2011) Peter Libby et al.   NATURE

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

(2011) Kasey C. Vickers et al.   NATURE CELL BIOLOGY

HDL and cardiovascular disease: atherogenic and atheroprotective mechanisms

(2011) Mohamad Navab et al.   Nature Reviews Cardiology

Novel HDL-directed pharmacotherapeutic strategies

(2011) Emil M. deGoma et al.   Nature Reviews Cardiology

Anti-inflammatory therapeutics for the treatment of atherosclerosis

(2011) Israel F. Charo et al.   NATURE REVIEWS DRUG DISCOVERY

Cholesterol Efflux Capacity, High-Density Lipoprotein Function, and Atherosclerosis

(2011) Amit V. Khera et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives

(2011) Jeng-Jiann Chiu et al.   PHYSIOLOGICAL REVIEWS

Standardization of Models and Methods Used to Assess Nanoparticles in Cardiovascular Applications

(2011) Kathleen T. Fitzgerald et al.   Small

Efficient Cytosolic Delivery of siRNA Using HDL-Mimicking Nanoparticles

(2011) Mi Yang et al.   Small

Microfabrication and nanotechnology in stent design

(2011) Adam W. Martinez et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Coronary Atherosclerosis Imaging by Coronary CT Angiography

(2011) Szilard Voros et al.   JACC-Cardiovascular Imaging

Target-specific delivery of peptide-based probes for PET imaging

(2010) Kai Chen et al.   ADVANCED DRUG DELIVERY REVIEWS

The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect

(2010) Jun Fang et al.   ADVANCED DRUG DELIVERY REVIEWS

The BioImage Study: Novel approaches to risk assessment in the primary prevention of atherosclerotic cardiovascular disease—study design and objectives

(2010) Pieter Muntendam et al.   AMERICAN HEART JOURNAL

Computed Tomography in Color: NanoK-Enhanced Spectral CT Molecular Imaging

(2010) Dipanjan Pan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Poly(ethylene glycol) in Drug Delivery: Pros and Cons as Well as Potential Alternatives

(2010) Katrin Knop et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Annexin A5-Functionalized Bimodal Nanoparticles for MRI and Fluorescence Imaging of Atherosclerotic Plaques

(2010) Geralda A. F. van Tilborg et al.   BIOCONJUGATE CHEMISTRY

The biological properties of iron oxide core high-density lipoprotein in experimental atherosclerosis

(2010) Torjus Skajaa et al.   BIOMATERIALS

Shear stress and the endothelial transport barrier

(2010) John M. Tarbell   CARDIOVASCULAR RESEARCH

Multimodality Imaging Probes: Design and Challenges

(2010) Angelique Louie   CHEMICAL REVIEWS

Challenges for Molecular Magnetic Resonance Imaging

(2010) Enzo Terreno et al.   CHEMICAL REVIEWS

Autonomic Denervation With Magnetic Nanoparticles

(2010) Lilei Yu et al.   CIRCULATION

Heart Disease and Stroke Statistics—2011 Update

(2010) Véronique L. Roger et al.   CIRCULATION

Contrast enhancement by differently sized paramagnetic MRI contrast agents in mice with two phenotypes of atherosclerotic plaque

(2010) Glenda S. van Bochove et al.   Contrast Media & Molecular Imaging

Atherosclerotic lesions in mouse and man: is it the same disease?

(2010) Jacob Fog Bentzon et al.   CURRENT OPINION IN LIPIDOLOGY

Angiogenesis imaging with vascular-constrained particles: the why and how

(2010) Gregory M. Lanza et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Local arterial nanoparticle delivery of siRNA for NOX2 knockdown to prevent restenosis in an atherosclerotic rat model

(2010) J M Li et al.   GENE THERAPY

An ultrasound-responsive nano delivery system of tissue-type plasminogen activator for thrombolytic therapy

(2010) Yoshiko Uesugi et al.   JOURNAL OF CONTROLLED RELEASE

In Vivo Imaging of Macrophage Activity in the Coronary Arteries Using 68Ga-DOTATATE PET/CT: Correlation with Coronary Calcium Burden and Risk Factors

(2010) A. Rominger et al.   JOURNAL OF NUCLEAR MEDICINE

In-Stent Restenosis in the Drug-Eluting Stent Era

(2010) George D. Dangas et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Imaging Atherosclerotic Plaque Inflammation by Fluorodeoxyglucose With Positron Emission Tomography

(2010) James H.F. Rudd et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Targeted Iron Oxide Particles for In Vivo Magnetic Resonance Detection of Atherosclerotic Lesions With Antibodies Directed to Oxidation-Specific Epitopes

(2010) Karen C. Briley-Saebo et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Intensive lowering of LDL cholesterol with 80 mg versus 20 mg simvastatin daily in 12 064 survivors of myocardial infarction: a double-blind randomised trial

(2010)   LANCET

Multimodal Clinical Imaging To Longitudinally Assess a Nanomedical Anti-Inflammatory Treatment in Experimental Atherosclerosis

(2010) Mark E. Lobatto et al.   MOLECULAR PHARMACEUTICS

Quantum Dot and Cy5.5 Labeled Nanoparticles to Investigate Lipoprotein Biointeractions via Förster Resonance Energy Transfer

(2010) Torjus Skajaa et al.   NANO LETTERS

Targeted Delivery of Nanoparticles to Ischemic Muscle for Imaging and Therapeutic Angiogenesis

(2010) Jaeyun Kim et al.   NANO LETTERS

Rational design of cationic lipids for siRNA delivery

(2010) Sean C Semple et al.   NATURE BIOTECHNOLOGY

Nanotechnological strategies for engineering complex tissues

(2010) Tal Dvir et al.   Nature Nanotechnology

MRI of carotid atherosclerosis: clinical implications and future directions

(2010) Hunter R. Underhill et al.   Nature Reviews Cardiology

Monocytes in atherosclerosis: subsets and functions

(2010) Kevin J. Woollard et al.   Nature Reviews Cardiology

Strategies in the design of nanoparticles for therapeutic applications

(2010) Robby A. Petros et al.   NATURE REVIEWS DRUG DISCOVERY

Nanomedicine

(2010) Betty Y.S. Kim et al.   NEW ENGLAND JOURNAL OF MEDICINE

Targeting stents with local delivery of paclitaxel-loaded magnetic nanoparticles using uniform fields

(2010) M. Chorny et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipid-like materials for low-dose, in vivo gene silencing

(2010) K. T. Love et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spatiotemporal controlled delivery of nanoparticles to injured vasculature

(2010) J. M. Chan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atherosclerotic Plaque Composition: Analysis with Multicolor CT and Targeted Gold Nanoparticles

(2010) David P. Cormode et al.   RADIOLOGY

A Light-Activated Theranostic Nanoagent for Targeted Macrophage Ablation in Inflammatory Atherosclerosis

(2010) Jason R. McCarthy et al.   Small

Rationale for a Nanomedicine Approach to Thrombolytic Therapy

(2010) G. M. Lanza et al.   STROKE

Nanoparticulate Assemblies of Amphiphiles and Diagnostically Active Materials for Multimodality Imaging

(2009) Willem J. M. Mulder et al.   ACCOUNTS OF CHEMICAL RESEARCH

Impact of Nanotechnology on Drug Delivery

(2009) Omid C. Farokhzad et al.   ACS Nano

Hybrid In Vivo FMT-CT Imaging of Protease Activity in Atherosclerosis With Customized Nanosensors

(2009) Matthias Nahrendorf et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Optical and Multimodality Molecular Imaging

(2009) Farouc A. Jaffer et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Structure and Function of HDL Mimetics

(2009) Mohamad Navab et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

High-Density Lipoprotein–Based Contrast Agents for Multimodal Imaging of Atherosclerosis

(2009) Torjus Skajaa et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Comparison of Synthetic High Density Lipoprotein (HDL) Contrast Agents for MR Imaging of Atherosclerosis

(2009) David P. Cormode et al.   BIOCONJUGATE CHEMISTRY

New Strategies for Fluorescent Probe Design in Medical Diagnostic Imaging

(2009) Hisataka Kobayashi et al.   CHEMICAL REVIEWS

The First-Generation Drug-Eluting Stents and Coronary Endothelial Dysfunction

(2009) Lakshmana K. Pendyala et al.   JACC-Cardiovascular Interventions

Formulation of Nanoparticle-Eluting Stents by a Cationic Electrodeposition Coating Technology

(2009) Kaku Nakano et al.   JACC-Cardiovascular Interventions

Fluorescent pegylated nanoparticles demonstrate fluid-phase pinocytosis by macrophages in mouse atherosclerotic lesions

(2009) Chiara Buono et al.   JOURNAL OF CLINICAL INVESTIGATION

Extracellular matrix binding mixed micelles for drug delivery applications

(2009) Conlin P. O'Neil et al.   JOURNAL OF CONTROLLED RELEASE

Templated Spherical High Density Lipoprotein Nanoparticles

(2009) C. Shad Thaxton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The ATHEROMA (Atorvastatin Therapy: Effects on Reduction of Macrophage Activity) Study

(2009) Tjun Y. Tang et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Iron Oxide Magnetic Resonance Imaging for Atherosclerosis Therapeutic Evaluation

(2009) Zahi A. Fayad et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Prolonged Targeting of Ischemic/Reperfused Myocardium by Liposomal Adenosine Augments Cardioprotection in Rats

(2009) Hiroyuki Takahama et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Promoting Mechanisms of Vascular Health

(2009) Pedro R. Moreno et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Inflammation in Atherosclerosis

(2009) Peter Libby et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Understanding biophysicochemical interactions at the nano–bio interface

(2009) Andre E. Nel et al.   NATURE MATERIALS

A highly sensitive and selective diagnostic assay based on virus nanoparticles

(2009) Jin-Seung Park et al.   Nature Nanotechnology

Molecular imaging of cardiovascular disease with contrast-enhanced ultrasonography

(2009) Jonathan R. Lindner   Nature Reviews Cardiology

Biodegradable dendritic positron-emitting nanoprobes for the noninvasive imaging of angiogenesis

(2009) Adah Almutairi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting atherosclerosis by using modular, multifunctional micelles

(2009) D. Peters et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intramural Delivery of Rapamycin With α v β 3 -Targeted Paramagnetic Nanoparticles Inhibits Stenosis After Balloon Injury

(2008) Tillmann Cyrus et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Site-Specific Targeting of Nanoparticle Prednisolone Reduces In-Stent Restenosis in a Rabbit Model of Established Atheroma

(2008) Michael Joner et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

In Vivo Monitoring of Inflammation After Cardiac and Cerebral Ischemia by Fluorine Magnetic Resonance Imaging

(2008) Ulrich Flögel et al.   CIRCULATION

Safety, pharmacokinetics, and pharmacodynamics of oral apoA-I mimetic peptide D-4F in high-risk cardiovascular patients

(2008) LeAnne T. Bloedon et al.   JOURNAL OF LIPID RESEARCH

Rapid Change in Plaque Size, Composition, and Molecular Footprint After Recombinant Apolipoprotein A-IMilano (ETC-216) Administration

(2008) Borja Ibanez et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Molecular Imaging of Matrix Metalloproteinase in Atherosclerotic Lesions

(2008) Shinichiro Fujimoto et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles

(2008) Frank Alexis et al.   MOLECULAR PHARMACEUTICS

Nanocrystal Core High-Density Lipoproteins: A Multimodality Contrast Agent Platform

(2008) David P. Cormode et al.   NANO LETTERS

Plasmonic Intravascular Photoacoustic Imaging for Detection of Macrophages in Atherosclerotic Plaques

(2008) Bo Wang et al.   NANO LETTERS

Imaging of atherosclerotic cardiovascular disease

(2008) Javier Sanz et al.   NATURE

Translating molecular discoveries into new therapies for atherosclerosis

(2008) Daniel J. Rader et al.   NATURE

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE

Physical approaches to biomaterial design

(2008) Samir Mitragotri et al.   NATURE MATERIALS

Nanoparticle-mediated cellular response is size-dependent

(2008) Wen Jiang et al.   Nature Nanotechnology

Nanoparticle therapeutics: an emerging treatment modality for cancer

(2008) Mark E. Davis et al.   NATURE REVIEWS DRUG DISCOVERY

Form to function: current and future roles for atherosclerosis imaging in drug development

(2008) Alistair C. Lindsay et al.   NATURE REVIEWS DRUG DISCOVERY

High field gradient targeting of magnetic nanoparticle-loaded endothelial cells to the surfaces of steel stents

(2008) B. Polyak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antiangiogenic Synergism of Integrin-Targeted Fumagillin Nanoparticles and Atorvastatin in Atherosclerosis

(2008) Patrick M. Winter et al.   JACC-Cardiovascular Imaging

Nanoparticle PET-CT Imaging of Macrophages in Inflammatory Atherosclerosis

(2007) Matthias Nahrendorf et al.   CIRCULATION