Heparan sulfate inhibitors and their therapeutic implications in inflammatory illnesses
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Heparan sulfate inhibitors and their therapeutic implications in inflammatory illnesses
Authors
Keywords
-
Journal
EXPERT OPINION ON THERAPEUTIC TARGETS
Volume 17, Issue 8, Pages 965-975
Publisher
Informa Healthcare
Online
2013-06-24
DOI
10.1517/14728222.2013.811491
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Sulfated Hexasaccharides Attenuate Metastasis by Inhibition of P-selectin and Heparanase
- (2015) Lubor Borsig et al. NEOPLASIA
- Antitumor efficacy of the heparanase inhibitor SST0001 alone and in combination with antiangiogenic agents in the treatment of human pediatric sarcoma models
- (2013) G. Cassinelli et al. BIOCHEMICAL PHARMACOLOGY
- The heparanase/syndecan-1 axis in cancer: mechanisms and therapies
- (2013) Vishnu C. Ramani et al. FEBS Journal
- Heparanase in inflammation and inflammation-associated cancer
- (2013) Amichay Meirovitz et al. FEBS Journal
- Synthesized Multiple Antigenic Polypeptide Vaccine Based on B-Cell Epitopes of Human Heparanase Could Elicit a Potent Antimetastatic Effect on Human Hepatocellular Carcinoma In Vivo
- (2013) Jun Zhang et al. PLoS One
- Heparanase overexpression impairs inflammatory response and macrophage-mediated clearance of amyloid-β in murine brain
- (2012) Xiao Zhang et al. ACTA NEUROPATHOLOGICA
- Deciphering Mode of Action of Heparanase Using Structurally Defined Oligosaccharides
- (2012) Sherket Peterson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Discovery of PG545: A Highly Potent and Simultaneous Inhibitor of Angiogenesis, Tumor Growth, and Metastasis
- (2012) Vito Ferro et al. JOURNAL OF MEDICINAL CHEMISTRY
- Heparosan-Derived Heparan Sulfate/Heparin-Like Compounds: One Kind of Potential Therapeutic Agents
- (2012) Pingli Li et al. MEDICINAL RESEARCH REVIEWS
- Multiple Antigenic Peptides Based on H-2Kb-Restricted CTL Epitopes from Murine Heparanase Induce a Potent Antitumor Immune Response In Vivo
- (2012) X.-D. Tang et al. MOLECULAR CANCER THERAPEUTICS
- Anti-metastatic Semi-synthetic Sulfated Maltotriose C-C Linked Dimers. Synthesis and Characterisation
- (2012) Elena Vismara et al. MOLECULES
- The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis
- (2012) Eric P Schmidt et al. NATURE MEDICINE
- Heparanase overexpression reduces carrageenan-induced mechanical and cold hypersensitivity in mice
- (2012) Lili Li et al. NEUROSCIENCE LETTERS
- Small RNAs Targeting Transcription Start Site Induce Heparanase Silencing through Interference with Transcription Initiation in Human Cancer Cells
- (2012) Guosong Jiang et al. PLoS One
- Development of Novel Single-Stranded Nucleic Acid Aptamers against the Pro-Angiogenic and Metastatic Enzyme Heparanase (HPSE1)
- (2012) Suzanne C. Simmons et al. PLoS One
- An Artificial miRNA against HPSE Suppresses Melanoma Invasion Properties, Correlating with a Down-Regulation of Chemokines and MAPK Phosphorylation
- (2012) Xiaoyan Liu et al. PLoS One
- PG545, a Heparan Sulfate Mimetic, Reduces Heparanase Expression In Vivo, Blocks Spontaneous Metastases and Enhances Overall Survival in the 4T1 Breast Carcinoma Model
- (2012) Edward Hammond et al. PLoS One
- Heparanase DNA vaccine delivered by electroporation induces humoral immunity and cytoimmunity in animal models
- (2012) Jie Fu et al. VACCINE
- Glycosaminoglycan analogs as a novel anti-inflammatory strategy
- (2012) India C. Severin et al. Frontiers in Immunology
- Molecular model of human heparanase with proposed binding mode of a heparan sulfate oligosaccharide and catalytic amino acids
- (2011) Nicolas Sapay et al. BIOPOLYMERS
- PG545, a dual heparanase and angiogenesis inhibitor, induces potent anti-tumour and anti-metastatic efficacy in preclinical models
- (2011) K Dredge et al. BRITISH JOURNAL OF CANCER
- MicroRNA-1258 Suppresses Breast Cancer Brain Metastasis by Targeting Heparanase
- (2011) L. Zhang et al. CANCER RESEARCH
- Role of Heparanase in Radiation-Enhanced Invasiveness of Pancreatic Carcinoma
- (2011) A. Meirovitz et al. CANCER RESEARCH
- SST0001, a Chemically Modified Heparin, Inhibits Myeloma Growth and Angiogenesis via Disruption of the Heparanase/Syndecan-1 Axis
- (2011) Joseph P. Ritchie et al. CLINICAL CANCER RESEARCH
- Heparanase Is Essential for the Development of Diabetic Nephropathy in Mice
- (2011) N. Gil et al. DIABETES
- Heparanase: a universal immunotherapeutic target in human cancers
- (2011) Ya-Fei Zhang et al. DRUG DISCOVERY TODAY
- Computational analyses of the catalytic and heparin-binding sites and their interactions with glycosaminoglycans in glycoside hydrolase family 79 endo-β-d-glucuronidase (heparanase)
- (2011) Neha S Gandhi et al. GLYCOBIOLOGY
- Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in mice
- (2011) Immanuel Lerner et al. JOURNAL OF CLINICAL INVESTIGATION
- Heparan sulfate and heparanase play key roles in mouse β cell survival and autoimmune diabetes
- (2011) Andrew F. Ziolkowski et al. JOURNAL OF CLINICAL INVESTIGATION
- Heparanase Levels Are Elevated in the Urine and Plasma of Type 2 Diabetes Patients and Associate with Blood Glucose Levels
- (2011) Itay Shafat et al. PLoS One
- M402, a Novel Heparan Sulfate Mimetic, Targets Multiple Pathways Implicated in Tumor Progression and Metastasis
- (2011) He Zhou et al. PLoS One
- Novel glycosaminoglycan biosynthetic inhibitors affect tumor-associated angiogenesis
- (2010) Karthik Raman et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- 4-Deoxy-4-fluoro-xyloside derivatives as inhibitors of glycosaminoglycan biosynthesis
- (2010) Yasuhiro Tsuzuki et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- A chemotactic gradient sequestered on endothelial heparan sulfate induces directional intraluminal crawling of neutrophils
- (2010) S. Massena et al. BLOOD
- Retinal heparanase expression in streptozotocin-induced diabetic rats
- (2010) Pingping Ma et al. CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE
- Attenuation of Tumor Growth by Formation of Antiproliferative Glycosaminoglycans Correlates with Low Acetylation of Histone H3
- (2010) Ulrika Nilsson et al. CANCER RESEARCH
- Heparin/heparan sulphate-based drugs
- (2010) Neha S. Gandhi et al. DRUG DISCOVERY TODAY
- A 4-deoxy analogue of N-acetyl-d-glucosamine inhibits heparan sulphate expression and growth factor binding in vitro
- (2010) Xander M.R. van Wijk et al. EXPERIMENTAL CELL RESEARCH
- Endothelial Heparan Sulfate Controls Chemokine Presentation in Recruitment of Lymphocytes and Dendritic Cells to Lymph Nodes
- (2010) Xingfeng Bao et al. IMMUNITY
- Trapped versus Soluble Chemokines: Functions in Leukocyte Adhesion and Motility
- (2010) Ronen Alon IMMUNITY
- Unraveling the Specificity of Heparanase Utilizing Synthetic Substrates
- (2010) Sherket B. Peterson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cross-talk between the p38α and JNK MAPK Pathways Mediated by MAP Kinase Phosphatase-1 Determines Cellular Sensitivity to UV Radiation
- (2010) Christopher J. Staples et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Synthesis and Biological Evaluation of Polysulfated Oligosaccharide Glycosides as Inhibitors of Angiogenesis and Tumor Growth
- (2010) Ken D. Johnstone et al. JOURNAL OF MEDICINAL CHEMISTRY
- Heparanase upregulates Th2 cytokines, ameliorating experimental autoimmune encephalitis
- (2010) Menachem Bitan et al. MOLECULAR IMMUNOLOGY
- Heparanase Promotes Engraftment and Prevents Graft versus Host Disease in Stem Cell Transplantation
- (2010) Menachem Bitan et al. PLoS One
- Development of a colorimetric assay for heparanase activity suitable for kinetic analysis and inhibitor screening
- (2009) Edward Hammond et al. ANALYTICAL BIOCHEMISTRY
- Phosphomannopentaose sulfate (PI-88) inhibits retinal leukostasis in diabetic rat
- (2009) Pingping Ma et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Structure-Function Approach Identifies a COOH-Terminal Domain That Mediates Heparanase Signaling
- (2009) L. Fux et al. CANCER RESEARCH
- Heparanase inhibitor PI-88 as adjuvant therapy for hepatocellular carcinoma after curative resection: A randomized phase II trial for safety and optimal dosage
- (2009) Chun-Jen Liu et al. JOURNAL OF HEPATOLOGY
- Comparison of Anticoagulant and Anti-Inflammatory Responses Using Enoxaparin Versus Unfractionated Heparin for Transesophageal Echocardiography-Guided Cardioversion of Atrial Fibrillation††A list of participating clinical sites appears in the Appendix.
- (2008) Debra Hoppensteadt et al. AMERICAN JOURNAL OF CARDIOLOGY
- Dramatic regulation of heparanase activity and angiogenesis gene expression in synovium from patients with rheumatoid arthritis
- (2008) Rachel W. Li et al. ARTHRITIS AND RHEUMATISM
- PI-88: a novel inhibitor of angiogenesis
- (2008) Ragini Kudchadkar et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Molecular Structure of Heparan Sulfate fromSpalax
- (2008) Elina Sandwall et al. JOURNAL OF BIOLOGICAL CHEMISTRY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started