M402, a Novel Heparan Sulfate Mimetic, Targets Multiple Pathways Implicated in Tumor Progression and Metastasis

PG545, a dual heparanase and angiogenesis inhibitor, induces potent anti-tumour and anti-metastatic efficacy in preclinical models

(2011) K Dredge et al.   BRITISH JOURNAL OF CANCER

SST0001, a Chemically Modified Heparin, Inhibits Myeloma Growth and Angiogenesis via Disruption of the Heparanase/Syndecan-1 Axis

(2011) Joseph P. Ritchie et al.   CLINICAL CANCER RESEARCH

Non-Invasive Detection of a Small Number of Bioluminescent Cancer Cells In Vivo

(2010) Jae-Beom Kim et al.   PLoS One

Multicentre phase I/II study of PI-88, a heparanase inhibitor in combination with docetaxel in patients with metastatic castrate-resistant prostate cancer

(2009) M. Khasraw et al.   ANNALS OF ONCOLOGY

FRAGMATIC: A randomised phase III clinical trial investigating the effect of fragmin® added to standard therapy in patients with lung cancer

(2009) Gareth O Griffiths et al.   BMC CANCER

Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis

(2009) John M.L. Ebos et al.   CANCER CELL

Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis

(2009) Marta Pàez-Ribes et al.   CANCER CELL

Impact of Venous Thromboembolism and Anticoagulation on Cancer and Cancer Survival

(2009) Nicole M. Kuderer et al.   JOURNAL OF CLINICAL ONCOLOGY

Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer

(2009) S. Ostrand-Rosenberg et al.   JOURNAL OF IMMUNOLOGY

Targeted Therapy for Advanced Colorectal Cancer — More Is Not Always Better

(2009) Robert J. Mayer   NEW ENGLAND JOURNAL OF MEDICINE

Abrogation of TGFβ Signaling in Mammary Carcinomas Recruits Gr-1+CD11b+ Myeloid Cells that Promote Metastasis

(2008) Li Yang et al.   CANCER CELL

Migratory neighbors and distant invaders: tumor-associated niche cells

(2008) J. Wels et al.   GENES & DEVELOPMENT

Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers

(2008) R. J. Leary et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

(2008) S. Jones et al.   SCIENCE