Molecular model of human heparanase with proposed binding mode of a heparan sulfate oligosaccharide and catalytic amino acids

PG545, a dual heparanase and angiogenesis inhibitor, induces potent anti-tumour and anti-metastatic efficacy in preclinical models

(2011) K Dredge et al.   BRITISH JOURNAL OF CANCER

Heparanase 2 Interacts with Heparan Sulfate with High Affinity and Inhibits Heparanase Activity

(2010) Flonia Levy-Adam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heparanase coagulation and cancer progression

(2009) Yona Nadir et al.   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

Structure-Function Approach Identifies a COOH-Terminal Domain That Mediates Heparanase Signaling

(2009) L. Fux et al.   CANCER RESEARCH

Basement membrane proteoglycans: Modulators Par Excellence of cancer growth and angiogenesis

(2009) Renato V. Iozzo et al.   MOLECULES AND CELLS

Protein structure prediction on the Web: a case study using the Phyre server

(2009) Lawrence A Kelley et al.   Nature Protocols

The Pfam protein families database

(2009) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

The Universal Protein Resource (UniProt) in 2010

(2009)   NUCLEIC ACIDS RESEARCH

Interactions between extracellular matrix and growth factors in wound healing

(2009) Gregory S. Schultz et al.   WOUND REPAIR AND REGENERATION

Heparin/Heparan Sulfate Biosynthesis

(2008) Pernilla Carlsson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cathepsin L Is Responsible for Processing and Activation of Proheparanase through Multiple Cleavages of a Linker Segment

(2008) Ghada Abboud-Jarrous et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Jpred 3 secondary structure prediction server

(2008) C. Cole et al.   NUCLEIC ACIDS RESEARCH

The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics

(2008) B. L. Cantarel et al.   NUCLEIC ACIDS RESEARCH