Synthesized Multiple Antigenic Polypeptide Vaccine Based on B-Cell Epitopes of Human Heparanase Could Elicit a Potent Antimetastatic Effect on Human Hepatocellular Carcinoma In Vivo

Hepatocellular carcinoma with extrahepatic metastasis

(2011) Koji Uchino et al.   CANCER

Cancer immunotherapy: Progress and challenges in the clinical setting

(2011)   EUROPEAN JOURNAL OF IMMUNOLOGY

Critical role of c-Jun N-terminal kinase in regulating bFGF-induced angiogenesis in vitro

(2011) Shen Kaikai et al.   JOURNAL OF BIOCHEMISTRY

Screening and identification of novel B cell epitopes in human heparanase and their anti-invasion property for hepatocellular carcinoma

(2009) Jian-min Yang et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Hepatocellular Carcinoma – Epidemiological Trends and Risk Factors

(2009) Kerstin Schütte et al.   DIGESTIVE DISEASES

Cell surface heparan sulfate released by heparanase promotes melanoma cell migration and angiogenesis

(2009) Madhuchhanda Roy et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Alternatively spliced Spalax heparanase inhibits extracellular matrix degradation, tumor growth, and metastasis

(2009) N. J. Nasser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heparanase: One Molecule with Multiple Functions in Cancer Progression

(2008) Israel Vlodavsky et al.   CONNECTIVE TISSUE RESEARCH

Molecular targeted therapies in hepatocellular carcinoma

(2008) Josep M. Llovet et al.   HEPATOLOGY

Heparanase Facilitates Cell Adhesion and Spreading by Clustering of Cell Surface Heparan Sulfate Proteoglycans

(2008) Flonia Levy-Adam et al.   PLoS One

Basement Membrane Proteins Play an Important Role in the Invasive Processes of Human Pancreatic Cancer Cells

(2007) Hirozumi Sawai et al.   JOURNAL OF SURGICAL RESEARCH