Applications of carbonic anhydrases inhibitors in renal and central nervous system diseases

Evaluating off-label uses of acetazolamide

(2018) Megan A. Van Berkel et al.   AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY

Results, meta-analysis and a first evaluation of UNOxR, the urinary nitrate-to-nitrite molar ratio, as a measure of nitrite reabsorption in experimental and clinical settings

(2018) Dimitrios Tsikas et al.   AMINO ACIDS

GC-MS determination of nitrous anhydrase activity of bovine and human carbonic anhydrase II and IV

(2018) Erik Hanff et al.   ANALYTICAL BIOCHEMISTRY

Carbonic anhydrase activators

(2018) Claudiu T Supuran   Future Medicinal Chemistry

Carbon- versus sulphur-based zinc binding groups for carbonic anhydrase inhibitors?

(2018) Claudiu T. Supuran   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Inhibition of carbonic anhydrase IX targets primary tumors, metastases, and cancer stem cells: Three for the price of one

(2018) Claudiu T. Supuran et al.   MEDICINAL RESEARCH REVIEWS

Determining the Rate of Carbonic Anhydrase Reaction in the Human Brain

(2018) Shizhe Li et al.   Scientific Reports

Psychoactive substances belonging to the amphetamine class potently activate brain carbonic anhydrase isoforms VA, VB, VII, and XII

(2017) Andrea Angeli et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Design and Synthesis of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs–CAIs) for the Treatment of Rheumatoid Arthritis

(2017) Silvia Bua et al.   JOURNAL OF MEDICINAL CHEMISTRY

Carbonic anhydrase activation enhances object recognition memory in mice through phosphorylation of the extracellular signal-regulated kinase in the cortex and the hippocampus

(2017) Lucas Canto de Souza et al.   NEUROPHARMACOLOGY

Acetazolamide lowers intracranial pressure and modulates the cerebrospinal fluid secretion pathway in healthy rats

(2017) Maria Uldall et al.   NEUROSCIENCE LETTERS

Structure and function of carbonic anhydrases

(2016) C. T. Supuran   BIOCHEMICAL JOURNAL

Advances in structure-based drug discovery of carbonic anhydrase inhibitors

(2016) Claudiu T. Supuran   Expert Opinion on Drug Discovery

Drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors

(2016) Claudiu T. Supuran   Expert Opinion on Drug Metabolism & Toxicology

Carbonic anhydrase inhibition and the management of neuropathic pain

(2016) Claudiu T. Supuran   Expert Review of Neurotherapeutics

Topiramate in Migraine Prevention: A 2016 Perspective

(2016) Stephen D. Silberstein   HEADACHE

The carbonic anhydrase inhibitor methazolamide prevents amyloid beta-induced mitochondrial dysfunction and caspase activation protecting neuronal and glial cells in vitro and in the mouse brain

(2016) Silvia Fossati et al.   NEUROBIOLOGY OF DISEASE

Carbonic anhydrase inhibition and the management of neuropathic pain

(2016) Claudiu T. Supuran   Expert Review of Neurotherapeutics

Methazolamide improves neurological behavior by inhibition of neuron apoptosis in subarachnoid hemorrhage mice

(2016) Mingchang Li et al.   Scientific Reports

Discovery and microassay of a nitrite-dependent carbonic anhydrase activity by stable-isotope dilution gas chromatography–mass spectrometry

(2015) Maximilian Zinke et al.   AMINO ACIDS

A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects

(2015) Fabrizio Carta et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Acetazolamide for the treatment of idiopathic intracranial hypertension

(2015) Claudiu T Supuran   Expert Review of Neurotherapeutics

Acetazolamide during acute hypoxia improves tissue oxygenation in the human brain

(2015) Kang Wang et al.   JOURNAL OF APPLIED PHYSIOLOGY

Carbonic anhydrase inhibition for the management of cerebral ischemia: in vivo evaluation of sulfonamide and coumarin inhibitors

(2015) Lorenzo Di Cesare Mannelli et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

How many carbonic anhydrase inhibition mechanisms exist?

(2015) Claudiu T. Supuran   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Carbonic anhydrase inhibition by acetazolamide reduces in vitro epileptiform synchronization

(2015) Shabnam Hamidi et al.   NEUROPHARMACOLOGY

Acetazolamide for the treatment of idiopathic intracranial hypertension

(2015) Claudiu T Supuran   Expert Review of Neurotherapeutics

An overview of the alpha-, beta- and gamma-carbonic anhydrases fromBacteria: can bacterial carbonic anhydrases shed new light on evolution of bacteria?

(2014) Clemente Capasso et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Impact of Acetazolamide and CPAP on Cortical Activity in Obstructive Sleep Apnea Patients

(2014) Katrin Stadelmann et al.   PLoS One

Anticonvulsant/antiepileptic carbonic anhydrase inhibitors: a patent review

(2013) Mayank Aggarwal et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Antiglaucoma carbonic anhydrase inhibitors: a patent review

(2013) Emanuela Masini et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Anticancer carbonic anhydrase inhibitors: a patent review (2008 – 2013)

(2013) Simona Maria Monti et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Antiobesity carbonic anhydrase inhibitors: a literature and patent review

(2013) Andrea Scozzafava et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Diuretics with carbonic anhydrase inhibitory action: a patent and literature review (2005 – 2013)

(2013) Fabrizio Carta et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?

(2012) Vincenzo Alterio et al.   CHEMICAL REVIEWS

Update on carbonic anhydrase inhibitors: a patent review (2008 – 2011)

(2012) Mayank Aggarwal et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Secondary and tertiary sulfonamides: a patent review (2008 – 2012)

(2012) Andrea Scozzafava et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Sulfonamides: a patent review (2008 – 2012)

(2012) Fabrizio Carta et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Structure-based drug discovery of carbonic anhydrase inhibitors

(2012) Claudiu T. Supuran   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Renal carbonic anhydrases are involved in the reabsorption of endogenous nitrite

(2012) Kristine Chobanyan-Jürgens et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Novel therapies for glaucoma: a patent review 2007 – 2011

(2011) Fabrizio Carta et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Interfering with pH regulation in tumours as a therapeutic strategy

(2011) Dario Neri et al.   NATURE REVIEWS DRUG DISCOVERY

Timolol Activates the Enzyme Activities of Human Carbonic Anhydrase I and II

(2010) Ayako Sugimoto et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Sildenafil is a strong activator of mammalian carbonic anhydrase isoforms I–XIV

(2009) T. Abdülkadir Coban et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Acetazolamide and midazolam act synergistically to inhibit neuropathic pain

(2009) Marina Asiedu et al.   PAIN

Carbonic anhydrase activators: Kinetic and X-ray crystallographic study for the interaction of d- and l-tryptophan with the mammalian isoforms I–XIV

(2008) Claudia Temperini et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

(2008) Claudiu T. Supuran   NATURE REVIEWS DRUG DISCOVERY